Results: 21
SEP‐363856 exerts neuroprotection through the PI3K/AKT/GSK‐3β signaling pathway in a dual‐hit neurodevelopmental model of schizophrenia‐like mice.
- Published in:
- Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22225
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- Publication type:
- Article
2‐(Methyl(phenyl)amino)‐N‐(phenyloxyphenyl)acetamide structural motif representing a framework for selective SIRT2 inhibition.
- Published in:
- Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22224
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- Publication type:
- Article
Validating linalool as a potential drug for breast cancer treatment based on machine learning and molecular docking.
- Published in:
- Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22223
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- Publication type:
- Article
Downregulation of HIGD1B induces mitochondria‐mediated apoptosis in gastric cancer cells by inactivating Akt and ERK pathways.
- Published in:
- Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22221
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- Publication type:
- Article
Vedolizumab in the treatment of Crohn's disease: A promising therapeutic approach.
- Published in:
- Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22220
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- Publication type:
- Article
Oxymatrine attenuates sepsis‐induced inflammation and organ injury via inhibition of HMGB1/RAGE/NF‐κB signaling pathway.
- Published in:
- Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22219
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- Publication type:
- Article
New benzimidazole‐oxadiazole derivatives as potent VEGFR‐2 inhibitors: Synthesis, anticancer evaluation, and docking study.
- Published in:
- Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22218
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- Publication type:
- Article
Vicinal diaryl pyrazole with tetrazole/urea scaffolds as selective angiotensin converting enzyme‐1/cyclooxygenase‐2 inhibitors: Design, synthesis, anti‐hypertensive, anti‐fibrotic, and anti‐inflammatory.
- Published in:
- Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22217
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- Publication type:
- Article
Explore new quinoxaline pharmacophore tethered sulfonamide fragments as in vitro α‐glucosidase, α‐amylase, and acetylcholinesterase inhibitors with ADMET and molecular modeling simulation.
- Published in:
- Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22216
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- Publication type:
- Article
Glucosyltriazole amphiphile treatment attenuates breast cancer by modulating the AMPK signaling.
- Published in:
- Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22215
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- Publication type:
- Article
Synthesis of new N‐(5,6‐methylenedioxybenzothiazole‐2‐yl)‐2‐[(substituted)thio/piperazine]acetamide/propanamide derivatives and evaluation of their AChE, BChE, and BACE‐1 inhibitory activities.
- Published in:
- Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22214
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- Publication type:
- Article
Asprosin aggravates nonalcoholic fatty liver disease via inflammation and lipid metabolic disturbance mediated by reactive oxygen species.
- Published in:
- Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22213
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- Publication type:
- Article
Newly synthesized acridone derivatives targeting lung cancer: A toxicity and xenograft model study.
- Published in:
- Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22212
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- Publication type:
- Article
Repurposing of drugs against bacterial infections: A pharmacovigilance‐based data mining approach.
- Published in:
- Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22211
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- Publication type:
- Article
Apigenin alleviates doxorubicin‐induced myocardial pyroptosis by inhibiting glycogen synthase kinase‐3β in vitro and in vivo.
- Published in:
- Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22196
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- Publication type:
- Article
Issue Information.
- Published in:
- Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22209
- Publication type:
- Article
Hesperidin, vanillic acid, and sinapic acid attenuate atorvastatin‐induced mitochondrial dysfunction via inhibition of mitochondrial swelling and maintenance of mitochondrial function in pancreas isolated mitochondria.
- Published in:
- Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22199
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- Publication type:
- Article
Pantoprazole suppresses carcinogenesis and growth of hepatocellular carcinoma by inhibiting glycolysis and Na<sup>+</sup>/H<sup>+</sup> exchange.
- Published in:
- Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22198
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- Publication type:
- Article
Design and synthesis of novel tetrabromophthalimide derivatives as potential tubulin inhibitors endowed with apoptotic induction for cancer treatment.
- Published in:
- Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22197
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- Publication type:
- Article
Modafinil lightens apoptosis and inflammatory response in hepatic ischemia‐reperfusion injury through inactivation of TLR9/Myd88/p38 signaling.
- Published in:
- Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22210
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- Publication type:
- Article
Unveiling the potential of antisense oligonucleotides: Mechanisms, therapies, and safety insights.
- Published in:
- Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22187
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- Publication type:
- Article