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Cover Image, Volume 85, Issue 1.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22176
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Early investigation of a novel SI306 theranostic prodrug for glioblastoma treatment.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22158
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Influence of β‐catenin signaling on neurogenesis in neuropsychiatric disorders: Anxiety and depression.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22157
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Bazedoxifene analogs as potential WDHD1 degraders and antitumor agents: Synthesis, evaluation and molecular dynamics simulation studies.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22155
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Tri‐substituted 1,3,5‐triazine‐based analogs as effective HIV‐1 non‐nucleoside reverse transcriptase inhibitors (NNRTIs): A systematic review.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22154
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N‐Substituted piperazine‐coupled imidazo[2,1‐b]thiazoles as inhibitors of Mycobacterium tuberculosis: Synthesis, evaluation, and docking studies.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22153
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- Article
Dendrobine regulates STAT3 to attenuate mitochondrial dysfunction and senescence in vascular endothelial cells triggered by oxidized low‐density lipoprotein.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22152
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Drug upgrade: A complete methodology from old drug to new chemical entities using Nematic Protein Organization Technique.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22151
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Costunolide attenuates high‐fat diet‐induced inflammation and oxidative stress in non‐alcoholic fatty liver disease.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22150
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- Article
FGF12 restrains mitochondria‐dependent ferroptosis in doxorubicin‐induced cardiomyocytes through the activation of FGFR1/AMPK/NRF2 signaling.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22149
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Design and synthesis of vancomycin‐functionalized ZnFe<sub>2</sub>O<sub>4</sub> nanoparticles as an effective antibacterial agent against methicillin‐resistant Staphylococcus aureus.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22148
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Combined chemotherapy of zoledronic acid and pamidronate in the treatment of bone metastases from nonsmall cell lung cancer and the effects on pain stress and bone metabolic indices.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22147
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- Article
Development and evaluation of multi‐functionalized sialic acid conjugated asiatic acid nanoconstruct to mitigate cognitive deficits in Alzheimer's disease.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22146
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- Article
Proteolysis‐targeting chimeras in antiviral therapy: Leveraging influenza virus and exosome‐mediated delivery for targeted protein degradation and therapeutic advancements.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22145
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- Article
Issue Information.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22144
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- Article
2‐Thioxo‐3,4‐dihydropyrimidine and thiourea endowed with sulfonamide moieties as dual EGFR<sup>T790M</sup> and VEGFR‐2 inhibitors: Design, synthesis, docking, and anticancer evaluations.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22143
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- Article
AKR1C3 silencing inhibits autophagy‐dependent glycolysis in thyroid cancer cells by inactivating ERK signaling.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22142
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- Article
Mechanism of gambogic acid repressing invasion and metastasis of colorectal cancer by regulating macrophage polarization via tumor cell‐derived extracellular vesicle‐shuttled miR‐21.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22141
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- Article
Everolimus inhibits hepatoblastoma by inducing autophagy‐dependent ferroptosis.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22140
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Comprehensive characterization and preclinical assessment of an imidazopyridine‐based anticancer lead molecule.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22139
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Exploring the potential of radiolabeled duramycin as an infection imaging probe.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22138
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- Article
CALCRL knockdown suppresses cancer stemness and chemoresistance in acute myeloid leukemia with FLT3‐ITD and DNM3TA‐R882 double mutations.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22137
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<sup>68</sup>Ga‐labeled, imatinib encapsulated, theranostic liposomes: Formulation, characterization, and in vitro evaluation of anticancer activity.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22136
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Novel sulfonamide‐phosphonate conjugates as carbonic anhydrase isozymes inhibitors.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22135
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- Article
Anti‐allodynic and anti‐hyperalgesic activity of (±)‐licarin A in neuropathic rats via NO‐cyclic‐GMP‐ATP‐sensitive K+ channel pathway.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22134
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Design, synthesis of novel chromene‐based scaffolds targeting hepatocellular carcinoma: Cell cycle arrest, cytotoxic effect against resistant cancer cells, apoptosis induction, and c‐Src inhibition.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22133
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Covalent inhibitors: An ambitious approach for the discovery of newer oncotherapeutics.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22132
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Function of proprotein convertase subtilisin/kexin type 9 and its role in central nervous system diseases: An update on clinical evidence.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22131
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- Article
AS602801 treatment suppresses breast cancer metastasis to the brain by interfering with gap‐junction communication by regulating Cx43 expression.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22124
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- Article
Heat‐shock protein A12A attenuates oxygen‐glucose deprivation/reoxygenation‐induced human brain microvascular endothelial cell dysfunction via PGC‐1α/SIRT3 pathway.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22130
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Discovery of N‐(phenylsulfonyl)thiazole‐2‐carboxamides as potent α‐glucosidase inhibitors.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22128
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Design, synthesis, and in‐silico study of novel triarylethylene analogs with dual anti‐estrogenic and serotonergic activity.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22127
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- Article
Nitroimidazole derivatives potentiated against tumor hypoxia: Design, synthesis, antitumor activity, molecular docking study, and QSAR study.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22126
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Medicinal polypharmacology: Exploration and exploitation of the polypharmacolome in modern drug development.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22125
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Investigation of the activity of a novel tropolone in osteosarcoma.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22129
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Indole‐based aryl sulfides target the cell wall of Staphylococcus aureus without detectable resistance.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22123
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- Article
A growth‐based assay using fluorescent protein emission to screen for S‐adenosylmethionine synthetase inhibitors.
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- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22122
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- Article