Title: The treatment of SSRI-Resistant Depression in Adolescents (TORDIA): in search of the best next step.
Authors: Brent, David A.
Abstract: The article presents information on the Treatment of SSRI-Resistant Depression in Adolescents study (TORDIA) which aimed to inform clinicians on the best next step in the treatment after a depressed adolescent did not respond to an adequate trial with a selective serotonin re-uptake inhibitor (SSRI). Treatment-resistant adolescents were randomized to four treatment strategies. The outcomes of acute treatment response and suicidal events are described. Clinical implications and recommendations for further research are discussed.
Subjects: DEPRESSION in adolescence; DEPRESSED persons; MENTAL depression; SEROTONIN uptake inhibitors; TEENAGER attitudes; SUICIDAL behavior
Publication: Depression & Anxiety (1091-4269), 2009, Vol 26, Issue 10, p871
ISSN: 1091-4269
Publication type: Academic Journal
DOI: 10.1002/da.20617

The treatment of SSRI-Resistant Depression in Adolescents (TORDIA): in search of the best next step.

Brent, David A.