Title: A combination of faecal and intratumour microbial community profiling reveals novel diagnostic and prognostic biomarkers for pancreatic tumours.
Authors: Wang, Wei; Qian, Cheng; Wang, Ting; Jiang, Yuetong; Zhou, Yiran; Liu, Kaiyu; Ma, Zhiyang; Liu, Pengyi; Wu, Yichi; Chen, Leying; Wang, Huaizhi; Zhou, Tingting
Abstract: A study published in the journal Clinical & Translational Medicine suggests that analyzing microbial communities could be a useful tool for diagnosing and predicting the prognosis of pancreatic tumors. The researchers examined fecal and intratumor microbial samples from patients with pancreatic tumors and healthy volunteers. They discovered that specific bacteria in fecal samples could potentially serve as non-invasive biomarkers for early detection of pancreatic tumors. Furthermore, they observed differences in the microbial composition of pancreatic tissues between malignant and non-malignant tumors. These findings indicate that microbial profiling may offer a promising approach for improving the early detection and treatment of pancreatic tumors.
Subjects: PANCREATIC tumors; PROGNOSIS; TUMOR markers; PANCREATIC cysts; MICROBIAL communities; FISHER discriminant analysis; DISEASE risk factors
Publication: Clinical & Translational Medicine, 2024, Vol 14, Issue 6, p1
ISSN: 2001-1326
Publication type: Academic Journal
DOI: 10.1002/ctm2.1726

A combination of faecal and intratumour microbial community profiling reveals novel diagnostic and prognostic biomarkers for pancreatic tumours.

Wang, Wei; Qian, Cheng; Wang, Ting; Jiang, Yuetong; Zhou, Yiran; Liu, Kaiyu; Ma, Zhiyang; Liu, Pengyi; Wu, Yichi; Chen, Leying; Wang, Huaizhi; Zhou, Tingting