Works matching DE "DRUG development"

Results: 5000

Abstracts.

Published in:

2008

By:

Srivastava, S.

Publication type:

Abstract

Genomic approach to biomarker identification and its recent applications.

Published in:

Cancer Biomarkers, 2006, v. 2, n. 3/4, p. 103, doi. 10.3233/CBM-2006-23-404

By:

He, Yudong D.

Publication type:

Article

The process chain for peptidomic biomarker discovery.

Published in:

Cancer Biomarkers, 2005, v. 1, n. 4/5, p. 235

By:

Schrader, Michael;
Selle, Hartmut

Publication type:

Article

Evaluating Protocols for Assessing Toxicological Effects of Ethnopharmacological Agents on the Central Nervous System.

Published in:

Tropical Journal of Health Sciences, 2025, v. 32, n. 1, p. 31, doi. 10.4314/tjhc.v32i1.5

By:

Umukoro, E. K.;
Elijah, O. B.;
Moke, E. G.

Publication type:

Article

Optimizing Chemotherapy Dose and Schedule by Norton-Simon Mathematical Modeling.

Published in:

Breast Disease, 2010, v. 31, n. 1, p. 7, doi. 10.3233/BD-2009-0290

By:

Traina, Tiffany A.;
Dugan, Ute;
Higgins, Brian;
Kolinsky, Kenneth;
Theodoulou, Maria;
Hudis, Clifford A.;
Norton, Larry

Publication type:

Article

Editorial: Striking the Right Balance for Eligibility Criteria for Clinical Trials in Inflammatory Bowel Disease.

Published in:

2025

By:

Solitano, Virginia;
Jairath, Vipul;
Danese, Silvio

Publication type:

Editorial

Efficient synthesis and characterization of imidazo[1,2‐a]pyridine‐8‐carboxamide derivatives: A promising scaffold for drug development.

Published in:

Vietnam Journal of Chemistry, 2024, v. 62, n. 4, p. 556, doi. 10.1002/vjch.202300362

By:

Bhatt, Keval;
Patel, Dhara;
Rathod, Mrudangsinh;
Patel, Ashish;
Shah, Drashti

Publication type:

Article

A Coalition to Advance Treatments for Parkinson's Disease, Dementia with Lewy Bodies, and Related Disorders.

Published in:

Journal of Parkinson's Disease, 2024, v. 14, n. 6, p. 1105, doi. 10.3233/JPD-230257

By:

Kopil, Catherine M.;
Asis, Angelica;
Campbell, Clyde;
Chowdhury, Sohini;
Dexter, David T.;
Fargo, Keith N.;
Lee, Karen K.;
Matthews, Helen;
Taylor, Angela;
Xiao, Yuge;
Stephenson, Diane

Publication type:

Article

This is NOT the End for Immunotherapy in Parkinson's Disease – A Perspective from Early Drug Development Scientists.

Published in:

Journal of Parkinson's Disease, 2022, v. 12, n. 8, p. 2293, doi. 10.3233/JPD-229008

By:

Brundin, Patrik;
Svoboda, Hanno;
Bonni, Azad;
Pagano, Gennaro

Publication type:

Article

Parkinson's Disease Drug Therapies in the Clinical Trial Pipeline: 2022 Update.

Published in:

Journal of Parkinson's Disease, 2022, v. 12, n. 4, p. 1073, doi. 10.3233/JPD-229002

By:

McFarthing, Kevin;
Rafaloff, Gary;
Baptista, Marco;
Mursaleen, Leah;
Fuest, Rosie;
Wyse, Richard K.;
Stott, Simon R.W.

Publication type:

Article

Parkinson's Disease Drug Therapies in the Clinical Trial Pipeline: 2021 Update.

Published in:

Journal of Parkinson's Disease, 2021, v. 11, n. 3, p. 891, doi. 10.3233/JPD-219006

By:

McFarthing, Kevin;
Rafaloff, Gary;
Baptista, Marco A.S.;
Wyse, Richard K.;
Stott, Simon R. W.

Publication type:

Article

Parkinson's Disease Drug Development Since 1999: A Story of Repurposing and Relative Success.

Published in:

Journal of Parkinson's Disease, 2021, v. 11, n. 2, p. 421, doi. 10.3233/JPD-202184

By:

Boucherie, Deirdre M.;
Duarte, Gonçalo S.;
Machado, Tiago;
Faustino, Patrícia R.;
Sampaio, Cristina;
Rascol, Olivier;
Ferreira, Joaquim J.

Publication type:

Article

Modeling Parkinson's Disease Using Patient-specific Induced Pluripotent Stem Cells.

Published in:

Journal of Parkinson's Disease, 2018, v. 8, n. 4, p. 479, doi. 10.3233/JPD-181353

By:

Li, Hong;
Jiang, Houbo;
Zhang, Boyang;
Feng, Jian

Publication type:

Article

Stomaching the Possibility of a Pathogenic Role for Helicobacter pylori in Parkinson’s Disease.

Published in:

Journal of Parkinson's Disease, 2018, v. 8, n. 3, p. 367, doi. 10.3233/JPD-181327

By:

McGee, David J.;
Lu, Xiao-Hong;
Disbrow, Elizabeth A.

Publication type:

Article

Rising to the Challenges of Clinical Trial Improvement in Parkinson's Disease.

Published in:

Journal of Parkinson's Disease, 2015, v. 5, n. 2, p. 263, doi. 10.3233/JPD-150541

By:

Mathur, Soania;
DeWitte, Steve;
Robledo, Israel;
Isaacs, Tom;
Stamford, Jon

Publication type:

Article

Drug discovery in the context of precision medicine and artificial intelligence.

Published in:

Expert Review of Precision Medicine & Drug Development, 2024, v. 9, n. 1, p. 42, doi. 10.1080/23808993.2024.2393089

By:

Hasanzad, Mandana;
Nosrati, Marzieh;
Khatami, Fatemeh;
Rahmani, Parham;
Sarhangi, Negar;
Nikfar, Shekoufeh;
Abdollahi, Mohammad

Publication type:

Article

Synthesis and Molecular Docking Study of Benzimidazole-Triazole Derivatives as Antifungal Agents.

Published in:

Journal of the Chemical Society of Pakistan, 2025, v. 47, n. 3, p. 267

By:

Maryam, Zahra;
Çevik, Ulviye Acar;
Kapavarapu, Ravikumar;
Guzel, Emir;
Kayis, Ugur;
Gul, Ülkuye Dudu;
Özkay, Yusuf;
Kaplancikli, Zafer Asim

Publication type:

Article

Elucidation of B-cell specific drug immunogenicity liabilities via a novel ex vivo assay.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1589483

By:

Looney, Cary M.;
Ducret, Axel;
Steiner, Guido;
Dernick, Karen;
Hartman, Katharina;
Siegel, Michel;
Hickling, Timothy;
Odermatt, Alex;
Marban-Doran, Céline

Publication type:

Article

ANTINOCICEPTIVE EFFECT OF P-CYMENE AND CINNAMALDEHYDE: THEIR RELATIONSHIP WITH THE L-ARGININE-NITRIC OXIDE PATHWAY IN RATS.

Published in:

Acta Veterinaria, 2025, v. 75, n. 2, p. 193, doi. 10.2478/acve-2025-0016

By:

MILOVANOVIĆ, Mirjana;
MARJANOVIĆ, Đorđe S.;
TRAILOVIĆ, Saša M.;
STOJANOVIĆ, Danilo

Publication type:

Article

Sex differences in the pharmacotherapy of neurological patients.

Published in:

Egyptian Journal of Neurology, Psychiatry & Neurosurgery, 2025, v. 61, n. 1, p. 1, doi. 10.1186/s41983-025-00990-5

By:

Ćorić, Lejla;
Gadže, Željka Petelin;
Hodžić, Asja;
Bošnjak, Jelena;
Papić, Karlo

Publication type:

Article

Multitarget inhibition of CDK2, EGFR, and tubulin by phenylindole derivatives: Insights from 3D-QSAR, molecular docking, and dynamics for cancer therapy.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0326245

By:

Al-Zaydi, Khadijah M.;
Baammi, Soukayna;
Moussaoui, Mohamed

Publication type:

Article

β‐Glucuronidase Inhibition in Drug Development: Emerging Strategies for Mitigating Drug‐Induced Toxicity and Enhancing Therapeutic Outcomes.

Published in:

Drug Development Research, 2025, v. 86, n. 4, p. 1, doi. 10.1002/ddr.70118

By:

Allam, Ahmed A.;
Rudayni, Hassan A.;
Ahmed, Noha A.;
Alkhayl, Faris F. Aba;
Lamsabhi, Al Mokhtar;
Kamel, Emadeldin M.

Publication type:

Article

Exploring 2‐Thioxo‐1,2,3,4‐tetrahydropyrimidines as Dual Acting GSK‐3β/Aβ Aggregation Inhibitors: Implications for Alzheimer's Disease Treatment.

Published in:

Drug Development Research, 2025, v. 86, n. 4, p. 1, doi. 10.1002/ddr.70112

By:

Sukanya, Sukanya;
Bellver‐Sanchis, Aina;
Choudhary, Bhanwar Singh;
Kumar, Sunil;
Pérez, Belén;
Rodríguez, Antón Leandro Martínez;
Brea, Jose;
Escolano, Carmen;
Griñán‐Ferré, Christian;
Malik, Ruchi

Publication type:

Article

A Multiple Imputation Workflow for Handling Missing Covariate Data in Pharmacometrics Modeling.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 6, p. 991, doi. 10.1002/psp4.70039

By:

Vuong, My‐Luong;
Verbeke, Geert;
Dreesen, Erwin

Publication type:

Article

Development of a Joint Tumor Size–Overall Survival Modeling and Simulation Framework Supporting Oncology Development Decision‐Making.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 6, p. 1006, doi. 10.1002/psp4.70002

By:

Struemper, Herbert;
Rathi, Chetan;
Muliaditan, Morris;
Goulooze, Sebastiaan C.;
Franzese, Richard C.;
Mantero, Alejandro;
Melhem, Murad;
Post, Teun M.;
Visser, Sandra A. G.

Publication type:

Article

Harnessing dual variational autoencoders to decode microbe roles in diseases for traditional medicine discovery.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1578140

By:

Ye, Qing;
Sun, Yaxin

Publication type:

Article

Contribution of multimodal ultrasound in evaluating the efficacy of lumbricus protein fast dissolving tablets against atherosclerotic plaques in ApoE<sup>(−/−)</sup> mice.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1551833

By:

Lu, Zhihao;
Wang, Ning;
Yu, Quanlin;
Feng, Jing;
Dong, Jianteng;
Zhao, Xu;
Cai, Chengke;
Li, Jian;
Zhong, Liqun

Publication type:

Article

Analyzing collaboration dynamics in new drug R&D: A case study of two lipid-lowering drugs.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1516882

By:

Zhang, Nan;
Guo, Huaqing;
Zhang, Mengchao;
Wang, Chen;
Tian, Ruonan;
Shi, Yan;
Duan, Zhiguang

Publication type:

Article

Advances on cancer vaccine trials registered in China and the USA in 2014-2024.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1557253

By:

Shi, Wei;
Chen, Zhuo;
Yu, Qin;
Zhang, Lingli

Publication type:

Article

Investigation of GPR137C as a promising novel marker for the progression of prostate cancer through G4 screen and bioinformatics analyses.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1576835

By:

Hou, Yue;
Lu, Haowen;
Chen, Saisai;
Mao, Likai;
Huang, Xuan;
Xu, Feng;
Shu, Chuanjun

Publication type:

Article

Research progress of B7-H3 in malignant tumors.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1586759

By:

Zhao, Shuaixiang;
Zhang, He;
Shang, Guanning

Publication type:

Article

In this Issue.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 118, n. 1, p. 9, doi. 10.1002/cpt.3710

By:

Gerding, Alethea

Publication type:

Article

Use of Real‐World Claims Data to Assess the Prevalence of Concomitant Medications to Inform Drug–Drug Interaction Risk in Target Patient Populations.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 118, n. 1, p. 146, doi. 10.1002/cpt.3652

By:

Tang, Alice S.;
Brooks, Logan;
Boudreau, Denise M.;
Chanu, Pascal;
Joshi, Amita;
Vora, Bianca;
Zhu, Rui

Publication type:

Article

Challenges and Possible Strategies to Address Them in Rare Disease Drug Development: A Statistical Perspective.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 118, n. 1, p. 62, doi. 10.1002/cpt.3631

By:

Chen, Jie;
Nie, Lei;
Lee, Shiowjen;
Chu, Haitao;
Tian, Haijun;
Wang, Yan;
He, Weili;
Jemielita, Thomas;
Gruber, Susan;
Song, Yang;
Tamura, Roy;
Tian, Lu;
Zhao, Yihua;
Chen, Yong;
van der Laan, Mark;
Lee, Hana

Publication type:

Article

Regulatory Perspective Based on Survey of Relationship Between Biopharmaceutical Characteristics and Food Effects on Systemic Pharmacokinetics.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 118, n. 1, p. 29, doi. 10.1002/cpt.3622

By:

Honma, Naoko;
Yamagishi, Kota;
Ideno, Yasuhisa;
Takaoka, Ryota;
Ishiguro, Akihiro

Publication type:

Article

Development and Validation of a Robust LC-MS/MS Method for Quantitation of a Novel Kinase Inhibitor, Ritlecitinib, in Rat Plasma: Application in Pharmacokinetic Study.

Published in:

Journal of Pharmacology & Pharmacotherapeutics, 2025, v. 16, n. 3, p. 302, doi. 10.1177/0976500X241289642

By:

Kumar, Katari Pavan;
Rao, Areti Anka

Publication type:

Article

Systematic Identification of Candidate Genes for Inherited Retinal Disease Gene Therapy Integrating Worldwide IRD Cohort and Single‐Cell Analysis.

Published in:

Journal of Ophthalmology, 2025, v. 2025, p. 1, doi. 10.1155/joph/7014745

By:

Wang, Ching-Yun;
Chen, Lawrence;
Lin, Ting-Yi;
Huang, Shun-Ping;
Ahmadieh, Hamid

Publication type:

Article

Recent progress in the development of localized drug delivery systems for oral mucosal disorders using mucoadhesive patches.

Published in:

Journal of Research in Pharmacy, 2025, v. 29, n. 3, p. 1350, doi. 10.12991/jrespharm.1712426

By:

TÜKÜÇ, Tuna Barkin;
ALARÇIN, Emine;
ÖZTÜRK, Ayça BAL

Publication type:

Article

Applying Machine Learning Techniques to Predict Drug-Related Side Effect: A Policy Brief.

Published in:

Inquiry (00469580), 2025, v. 62, p. 1, doi. 10.1177/00469580251335805

By:

Toni, Esmaeel;
Ayatollahi, Haleh

Publication type:

Article

Evaluation of the α-amylase, α-glucosidase, and tyrosinase inhibitory and photoprotective activities of organic solvent and aqueous Extracts of Retama monosperma stem.

Published in:

Tropical Journal of Natural Product Research, 2025, v. 9, n. 5, p. 2357, doi. 10.26538/tjnpr/v9i5.66

By:

Benkhouili, Fatima Zahra;
Moutawalli, Amina;
Benzeid, Hanane;
Doukkali, Anass;
Zahidi, Ahmed

Publication type:

Article

Antirheumatic Potential of Araucaria-Derived Biflavonoids through In Silico Docking to 20S Proteasome.

Published in:

Tropical Journal of Natural Product Research, 2025, v. 9, n. 5, p. 2043, doi. 10.26538/tjnpr/v9i5.24

By:

Irfana, Luthfan;
Suryawan, Chinesia P.;
Arifin, Budi;
Achmadi, Suminar S.;
Wahyudi, Setyanto T.;
Sugita, Purwantiningsih

Publication type:

Article

The Premise of the Paradox: Examining the Evidence That Motivated GIPR Agonist and Antagonist Drug Development Programs.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 11, p. 3812, doi. 10.3390/jcm14113812

By:

Douros, Jonathan D.;
Mowery, Stephanie A.;
Knerr, Patrick J.

Publication type:

Article

Prediction of Interspecies Translation for Targeting Delivery Coefficients of GalNAc-siRNA Silencing Apolipoprotein C-III Using a Mechanistic Minimal Physiologically Based Pharmacokinetic/Pharmacodynamic Model.

Published in:

Clinical Pharmacokinetics, 2025, v. 64, n. 6, p. 865, doi. 10.1007/s40262-025-01513-4

By:

Tian, Zhiteng;
Luo, Hui;
Chu, Yantao;
Liu, Yanhong;
Gao, Shan;
Song, Ling;
Yang, Zhenzhen;
Liu, Dongyang

Publication type:

Article

槲皮素防治肝细胞癌相关信号通路研究进展.

Published in:

Evaluation & Analysis of Drug-Use in Hospitals of China / Zhongguo Yiyuan Yongyao Pingjia yu Fenxi, 2025, v. 25, n. 5, p. 632, doi. 10.14009/j.issn.1672-2124.2025.05.025

By:

姚三飞;
刘江凯

Publication type:

Article

A State-of-the-Art Review on Recent Biomedical Application of Polysaccharide-Based Niosomes as Drug Delivery Systems.

Published in:

Polymers (20734360), 2025, v. 17, n. 11, p. 1566, doi. 10.3390/polym17111566

By:

Iacob, Andreea-Teodora;
Ababei-Bobu, Andra;
Chirliu, Oana-Maria;
Lupascu, Florentina Geanina;
Vasincu, Ioana-Mirela;
Apotrosoaei, Maria;
Profire, Bianca-Stefania;
Tauser, Georgiana-Roxana;
Lupascu, Dan;
Profire, Lenuta

Publication type:

Article

Lymphatic Metastasis of Esophageal Squamous Cell Carcinoma: The Role of NRF2 and Therapeutic Strategies.

Published in:

Cancers, 2025, v. 17, n. 11, p. 1853, doi. 10.3390/cancers17111853

By:

Li, Yahui;
Ladd, Zachary;
Xiong, Zhaohui;
Bui-Linh, Candice;
Paiboonrungruang, Chorlada;
Subramaniyan, Boopathi;
Li, Huan;
Wang, Haining;
Balch, Curt;
Shersher, David D.;
Spitz, Francis;
Chen, Xiaoxin

Publication type:

Article

Personalized Treatment in Ovarian Cancer: A Review of Disease Monitoring, Biomarker Expression, and Targeted Treatments for Advanced, Recurrent Ovarian Cancers.

Published in:

Cancers, 2025, v. 17, n. 11, p. 1822, doi. 10.3390/cancers17111822

By:

Ettorre, Victoria M.;
AlAshqar, Abdelrahman;
Sethi, Namrata;
Santin, Alessandro D.

Publication type:

Article

Bacopa monnieri : Preclinical and Clinical Evidence of Neuroactive Effects, Safety of Use and the Search for Improved Bioavailability.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1939, doi. 10.3390/nu17111939

By:

Gościniak, Anna;
Stasiłowicz-Krzemień, Anna;
Szeląg, Marta;
Pawlak, Jakub;
Skiera, Izabela;
Kwiatkowska, Hanna;
Nowak, Natasza;
Bernady, Krzysztof;
Trzaskoma, Piotr;
Zimak-Krótkopad, Oskar;
Cielecka-Piontek, Judyta

Publication type:

Article

Aqueous Extract of Freshwater Clam Increases Alcohol Metabolism in Rats in a Preclinical Model.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1915, doi. 10.3390/nu17111915

By:

Chung, Pei-Ying;
Chiu, I-Chen;
Kuan, Ching-Yi;
Wu, Tsung-Meng;
Tseng, Kuo-Chan;
Chuang, Shu-Ting;
Tsai, Sen-Wei;
Chen, Yu-Kuo

Publication type:

Article

Anti-Inflammatory Potential of Essential Oil from the Heart-Wood of the Folk Medicinal Tree Cinnamomum kanehirai Hayata in Macrophages.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5419, doi. 10.3390/ijms26115419

By:

Liu, May-Lan;
Liu, Pang-Yen;
Chao, Louis Kuoping;
Yang, Tzu-Jung;
Li, Lan-Hui;
Weng, Yih-Ming;
Sommano, Sarana Rose;
Unpaprom, Yuwalee;
Ramaraj, Rameshprabu;
Ho, Chen-Lung;
Hua, Kuo-Feng

Publication type:

Article