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Utility of Cytochrome P450 4F2 Genotyping to Assess Drug Interaction Risk for Brincidovovir, a Cytochrome P450 4F2 Substrate.
Published in:
Clinical Pharmacology in Drug Development, 2024, v. 13, n. 3, p. 288, doi. 10.1002/cpdd.1356
By:
- Tippin, Tim;
- Faison, Shamia;
- Schuck, Virna;
- Dunn, John;
- Naderer, Odin
Publication type:
Article
Improving the Efficiency of Clinical Pharmacology Studies.
Published in:
Clinical Pharmacology in Drug Development, 2023, v. 12, n. 8, p. 771, doi. 10.1002/cpdd.1274
By:
- Polasek, Thomas M.;
- Schuck, Virna
Publication type:
Article
Corrigendum: Responding to the challenge of untreatable gonorrhea: ETX0914, a first-in-class agent with a distinct mechanism-of-action against bacterial Type II topoisomerases.
Published in:
Scientific Reports, 2015, p. 14157, doi. 10.1038/srep14157
By:
- Basarab, Gregory S.;
- Kern, Gunther H.;
- McNulty, John;
- Mueller, John P.;
- Lawrence, Kenneth;
- Vishwanathan, Karthick;
- Alm, Richard A.;
- Barvian, Kevin;
- Doig, Peter;
- Galullo, Vincent;
- Gardner, Humphrey;
- Gowravaram, Madhusudhan;
- Huband, Michael;
- Kimzey, Amy;
- Morningstar, Marshall;
- Kutschke, Amy;
- Lahiri, Sushmita D.;
- Perros, Manos;
- Singh, Renu;
- Schuck, Virna J. A.
Publication type:
Article
Preclinical Pharmacokinetic/Pharmacodynamic Modeling and Simulation in the Pharmaceutical Industry: An IQ Consortium Survey Examining the Current Landscape.
Published in:
AAPS Journal, 2015, v. 17, n. 2, p. 462, doi. 10.1208/s12248-014-9716-2
By:
- Schuck, Edgar;
- Bohnert, Tonika;
- Chakravarty, Arijit;
- Damian-Iordache, Valeriu;
- Gibson, Christopher;
- Hsu, Cheng-Pang;
- Heimbach, Tycho;
- Krishnatry, Anu;
- Liederer, Bianca;
- Lin, Jing;
- Maurer, Tristan;
- Mettetal, Jerome;
- Mudra, Daniel;
- Nijsen, Marjoleen;
- Raybon, Joseph;
- Schroeder, Patricia;
- Schuck, Virna;
- Suryawanshi, Satyendra;
- Su, Yaming;
- Trapa, Patrick
Publication type:
Article
Translational Population‐Pharmacodynamic Modeling of a Novel Long‐Acting siRNA Therapy, Inclisiran, for the Treatment of Hypercholesterolemia.
Published in:
Clinical Pharmacology & Therapeutics, 2023, v. 113, n. 2, p. 328, doi. 10.1002/cpt.2774
By:
- Gosselin, Nathalie H.;
- Schuck, Virna J. A.;
- Barriere, Olivier;
- Kulmatycki, Kenneth;
- Margolskee, Alison;
- Smith, Patrick;
- He, YanLing
Publication type:
Article
Model‐Informed Drug Development for Anti‐Infectives: State of the Art and Future.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 867, doi. 10.1002/cpt.2198
By:
- Rayner, Craig R.;
- Smith, Patrick F.;
- Andes, David;
- Andrews, Kayla;
- Derendorf, Hartmut;
- Friberg, Lena E.;
- Hanna, Debra;
- Lepak, Alex;
- Mills, Edward;
- Polasek, Thomas M.;
- Roberts, Jason A.;
- Schuck, Virna;
- Shelton, Mark J.;
- Wesche, David;
- Rowland‐Yeo, Karen
Publication type:
Article
Translating slow-binding inhibition kinetics into cellular and in vivo effects.
Published in:
Nature Chemical Biology, 2015, v. 11, n. 6, p. 416, doi. 10.1038/nchembio.1796
By:
- Walkup, Grant K;
- You, Zhiping;
- Ross, Philip L;
- Allen, Eleanor K H;
- Daryaee, Fereidoon;
- Hale, Michael R;
- O'Donnell, John;
- Ehmann, David E;
- Schuck, Virna J A;
- Buurman, Ed T;
- Choy, Allison L;
- Hajec, Laurel;
- Murphy-Benenato, Kerry;
- Marone, Valerie;
- Patey, Sara A;
- Grosser, Lena A;
- Johnstone, Michele;
- Walker, Stephen G;
- Tonge, Peter J;
- Fisher, Stewart L
Publication type:
Article
A mathematical model-based analysis of the time-kill kinetics of ceftazidime/avibactam against Pseudomonas aeruginosa.
Published in:
2018
By:
- Sy, Sherwin K. B.;
- Luning Zhuang;
- Huiming Xia;
- Beaudoin, Marie-Eve;
- Schuck, Virna J.;
- Nichols, Wright W.;
- Derendorf, Hartmut;
- Zhuang, Luning;
- Xia, Huiming
Publication type:
journal article
Potentiation of ceftazidime by avibactam against β-lactam-resistant Pseudomonas aeruginosa in an in vitro infection model.
Published in:
2017
By:
- Sy, Sherwin K. B.;
- Luning Zhuang;
- Beaudoin, Marie-Eve;
- Kircher, Philipp;
- Tabosa, Maria A. M.;
- Cavalcanti, Noely C. T.;
- Grunwitz, Christian;
- Pieper, Sebastian;
- Schuck, Virna J.;
- Nichols, Wright W.;
- Derendorf, Hartmut;
- Zhuang, Luning
Publication type:
journal article
In vitro pharmacokinetics/pharmacodynamics of the combination of avibactam and aztreonam against MDR organisms.
Published in:
2016
By:
- Sy, Sherwin K. B.;
- Beaudoin, Marie-Eve;
- Luning Zhuang;
- Löblein, Kathrin I.;
- Lux, Clemens;
- Kissel, Marlene;
- Tremmel, Robin;
- Frank, Christian;
- Strasser, Severin;
- Heuberger, Jules A. A. C.;
- Mulder, Midas B.;
- Schuck, Virna J.;
- Derendorf, Hartmut;
- Zhuang, Luning
Publication type:
journal article

Found: 10