Works matching IS 18607179 AND DT 2021 AND VI 16 AND IP 18

Results: 18

Front Cover: Albumin Conjugates of Thiosemicarbazone and Imidazole‐2‐thione Prochelators: Iron Coordination and Antiproliferative Activity (ChemMedChem 18/2021).

Published in:

ChemMedChem, 2021, v. 16, n. 18, p. 2731, doi. 10.1002/cmdc.202100579

By:

Sung, Yu‐Shien;
Wu, Wangbin;
Ewbank, Megan A.;
Utterback, Rachel D.;
Marty, Michael T.;
Tomat, Elisa

Publication type:

Article

Functionalized Cyclopentenones and an Oxime Ether as Antimicrobial Agents.

Published in:

ChemMedChem, 2021, v. 16, n. 18, p. 2781, doi. 10.1002/cmdc.202100369

By:

Gomes, Rafael F. A.;
Isca, Vera M. S.;
Andrade, Késsia;
Rijo, Patrícia;
Afonso, Carlos A. M.

Publication type:

Article

1,3‐Benzodioxole‐Modified Noscapine Analogues: Synthesis, Antiproliferative Activity, and Tubulin‐Bound Structure.

Published in:

ChemMedChem, 2021, v. 16, n. 18, p. 2882, doi. 10.1002/cmdc.202100363

By:

Yong, Cassandra;
Devine, Shane M.;
Abel, Anne‐Catherine;
Tomlins, Stefan D.;
Muthiah, Divya;
Gao, Xuexin;
Callaghan, Richard;
Steinmetz, Michel O.;
Prota, Andrea E.;
Capuano, Ben;
Scammells, Peter J.

Publication type:

Article

What We Learned in 25 Years of Interactive Molecular Design Sessions.

Published in:

ChemMedChem, 2021, v. 16, n. 18, p. 2760, doi. 10.1002/cmdc.202100351

By:

Kuhn, Bernd;
Haap, Wolfgang;
Obst‐Sander, Ulrike;
Kramer, Christian;
Stahl, Martin

Publication type:

Article

A Computer‐Driven Scaffold‐Hopping Approach Generating New PTP1B Inhibitors from the Pyrrolo[1,2‐a]quinoxaline Core.

Published in:

ChemMedChem, 2021, v. 16, n. 18, p. 2895, doi. 10.1002/cmdc.202100338

By:

García‐Marín, Javier;
Griera, Mercedes;
Alajarín, Ramón;
Rodríguez‐Puyol, Manuel;
Rodríguez‐Puyol, Diego;
Vaquero, Juan J.

Publication type:

Article

Chemical and Structural Strategies to Selectively Target mTOR Kinase.

Published in:

ChemMedChem, 2021, v. 16, n. 18, p. 2744, doi. 10.1002/cmdc.202100332

By:

Borsari, Chiara;
De Pascale, Martina;
Wymann, Matthias P.

Publication type:

Article

A Fluorometric CYP19A1 (Aromatase) Activity Assay in Live Cells.

Published in:

ChemMedChem, 2021, v. 16, n. 18, p. 2845, doi. 10.1002/cmdc.202100326

By:

Heidary, David K.;
Kriger, Sarah M.;
Hachey, Austin C.;
Glazer, Edith C.

Publication type:

Article

Pyrazole‐Thiazole Core‐Containing Analogs Exhibit Adjunctive Activity with Meropenem against Carbapenem‐Resistant Enterobacteriaceae (CRE).

Published in:

ChemMedChem, 2021, v. 16, n. 18, p. 2775, doi. 10.1002/cmdc.202100321

By:

Kim, Chungsik;
Kassu, Mintesinot;
Smith, Kenneth P.;
Kirby, James E.;
Manetsch, Roman

Publication type:

Article

One Key and Multiple Locks: Substrate Binding in Structures of Tryptophan Dioxygenases and Hydroxylases.

Published in:

ChemMedChem, 2021, v. 16, n. 18, p. 2732, doi. 10.1002/cmdc.202100312

By:

Mammoli, Andrea;
Riccio, Alessandra;
Bianconi, Elisa;
Coletti, Alice;
Camaioni, Emidio;
Macchiarulo, Antonio

Publication type:

Article

Structure‐Activity Relationship and Mode‐Of‐Action Studies Highlight 1‐(4‐Biphenylylmethyl)‐1H‐imidazole‐Derived Small Molecules as Potent CYP121 Inhibitors.

Published in:

ChemMedChem, 2021, v. 16, n. 18, p. 2786, doi. 10.1002/cmdc.202100283

By:

Walter, Isabell;
Adam, Sebastian;
Gentilini, Maria Virginia;
Kany, Andreas M.;
Brengel, Christian;
Thomann, Andreas;
Sparwasser, Tim;
Köhnke, Jesko;
Hartmann, Rolf W.

Publication type:

Article

Albumin Conjugates of Thiosemicarbazone and Imidazole‐2‐thione Prochelators: Iron Coordination and Antiproliferative Activity.

Published in:

ChemMedChem, 2021, v. 16, n. 18, p. 2764, doi. 10.1002/cmdc.202100278

By:

Sung, Yu‐Shien;
Wu, Wangbin;
Ewbank, Megan A.;
Utterback, Rachel D.;
Marty, Michael T.;
Tomat, Elisa

Publication type:

Article

Structural Development of Salicylanilide‐Based SPAK Inhibitors as Candidate Antihypertensive Agents.

Published in:

ChemMedChem, 2021, v. 16, n. 18, p. 2817, doi. 10.1002/cmdc.202100273

By:

Fujii, Shinya;
Kikuchi, Eriko;
Suzuyama, Honoka;
Watanabe, Yuko;
Ishigami‐Yuasa, Mari;
Masuno, Hiroyuki;
Mori, Takayasu;
Isobe, Kiyoshi;
Uchida, Shinichi;
Kagechika, Hiroyuki

Publication type:

Article

Identification of the FDA‐Approved Drug Pyrvinium as a Small‐Molecule Inhibitor of the PD‐1/PD‐L1 Interaction.

Published in:

ChemMedChem, 2021, v. 16, n. 18, p. 2769, doi. 10.1002/cmdc.202100264

By:

Fattakhova, Elena;
Hofer, Jeremy;
DiFlumeri, Juliette;
Cobb, Madison;
Dando, Timothy;
Romisher, Zachary;
Wellington, Justin;
Oravic, Michael;
Radnoff, Madison;
Patil, Sachin P.

Publication type:

Article

Polysubstituted Pyrimidines as Potent Inhibitors of Prostaglandin E<sub>2</sub> Production: Increasing Aqueous Solubility.

Published in:

ChemMedChem, 2021, v. 16, n. 18, p. 2802, doi. 10.1002/cmdc.202100263

By:

Kalčic, Filip;
Kolman, Viktor;
Zídek, Zdeněk;
Janeba, Zlatko

Publication type:

Article

Design, Synthesis and Evaluation of a Series of 1,5‐Diaryl‐1,2,3‐triazole‐4‐carbohydrazones as Inhibitors of the YAP‐TAZ/TEAD Complex.

Published in:

ChemMedChem, 2021, v. 16, n. 18, p. 2823, doi. 10.1002/cmdc.202100153

By:

Gibault, Floriane;
Sturbaut, Manon;
Coevoet, Mathilde;
Pugnière, Martine;
Burtscher, Ashley;
Allemand, Frédéric;
Melnyk, Patricia;
Hong, Wanjin;
Rubin, Brian P.;
Pobbati, Ajaybabu V.;
Guichou, Jean‐François;
Cotelle, Philippe;
Bailly, Fabrice

Publication type:

Article

Synthesis and Biological Evaluation of Dantrolene‐Like Hydrazide and Hydrazone Analogues as Multitarget Agents for Neurodegenerative Diseases.

Published in:

ChemMedChem, 2021, v. 16, n. 18, p. 2807, doi. 10.1002/cmdc.202100209

By:

Bolognino, Isabella;
Giangregorio, Nicola;
Tonazzi, Annamaria;
Martínez, Antón L.;
Altomare, Cosimo D.;
Loza, María I.;
Sablone, Sara;
Cellamare, Saverio;
Catto, Marco

Publication type:

Article

Cytotoxic 1,2,3‐Triazoles as Potential Leads Targeting the S100A2‐p53 Complex: Synthesis and Cytotoxicity.

Published in:

ChemMedChem, 2021, v. 16, n. 18, p. 2864, doi. 10.1002/cmdc.202000950

By:

Sun, Jufeng;
Baker, Jennifer R.;
Russell, Cecilia C.;
Cossar, Peter J.;
Ngoc Thuy Pham, Hong;
Sakoff, Jennette A.;
Scarlett, Christopher J.;
McCluskey, Adam

Publication type:

Article

Targeting the S100A2‐p53 Interaction with a Series of 3,5‐Bis(trifluoromethyl)benzene Sulfonamides: Synthesis and Cytotoxicity.

Published in:

ChemMedChem, 2021, v. 16, n. 18, p. 2851, doi. 10.1002/cmdc.202000949

By:

Sun, Jufeng;
Ambrus, Joey I.;
Russell, Cecilia C.;
Baker, Jennifer R.;
Cossar, Peter J.;
Pirinen, Melanie J.;
Sakoff, Jennette A.;
Scarlett, Christopher J.;
McCluskey, Adam

Publication type:

Article