Works matching IS 18607179 AND DT 2021 AND VI 16 AND IP 11

Results: 15

Front Cover: E7766, a Macrocycle‐Bridged Stimulator of Interferon Genes (STING) Agonist with Potent Pan‐Genotypic Activity (ChemMedChem 11/2021).

Published in:

ChemMedChem, 2021, v. 16, n. 11, p. 1680, doi. 10.1002/cmdc.202100346

By:

Kim, Dae‐Shik;
Endo, Atsushi;
Fang, Francis G.;
Huang, Kuan‐Chun;
Bao, Xingfeng;
Choi, Hyeong‐wook;
Majumder, Utpal;
Shen, Young Y.;
Mathieu, Steven;
Zhu, Xiaojie;
Sanders, Kristen;
Noland, Thomas;
Hao, Ming‐Hong;
Chen, Yu;
Wang, John Y.;
Yasui, So;
TenDyke, Karen;
Wu, Jiayi;
Ingersoll, Christy;
Loiacono, Kara A.

Publication type:

Article

Thiazolidinediones: An In–Depth Study of Their Synthesis and Application to Medicinal Chemistry in the Treatment of Diabetes Mellitus.

Published in:

ChemMedChem, 2021, v. 16, n. 11, p. 1716, doi. 10.1002/cmdc.202100177

By:

Long, Nathan;
Le Gresley, Adam;
Wren, Stephen P.

Publication type:

Article

Hydroxypyridinethione Inhibitors of Human Insulin‐Degrading Enzyme.

Published in:

ChemMedChem, 2021, v. 16, n. 11, p. 1775, doi. 10.1002/cmdc.202100111

By:

Adamek, Rebecca N.;
Suire, Caitlin N.;
Stokes, Ryjul W.;
Brizuela, Monica K.;
Cohen, Seth M.;
Leissring, Malcolm A.

Publication type:

Article

E7766, a Macrocycle‐Bridged Stimulator of Interferon Genes (STING) Agonist with Potent Pan‐Genotypic Activity.

Published in:

ChemMedChem, 2021, v. 16, n. 11, p. 1740, doi. 10.1002/cmdc.202100068

By:

Kim, Dae‐Shik;
Endo, Atsushi;
Fang, Francis G.;
Huang, Kuan‐Chun;
Bao, Xingfeng;
Choi, Hyeong‐wook;
Majumder, Utpal;
Shen, Young Y.;
Mathieu, Steven;
Zhu, Xiaojie;
Sanders, Kristen;
Noland, Thomas;
Hao, Ming‐Hong;
Chen, Yu;
Wang, John Y.;
Yasui, So;
TenDyke, Karen;
Wu, Jiayi;
Ingersoll, Christy;
Loiacono, Kara A.

Publication type:

Article

Cyclopentadienyl‐Based Anticancer Drugs: Improvement of Cytotoxic Activity through Functionalisation of the π Ligand.

Published in:

ChemMedChem, 2021, v. 16, n. 11, p. 1804, doi. 10.1002/cmdc.202100060

By:

Absolonová, Monika;
Melounková, Lucie;
Vinklárek, Jaromír;
Honzíček, Jan;
Dostál, Libor;
Mrózek, Ondřej

Publication type:

Article

Using Theory To Extend the Scope of Azobenzene Drugs in Chemotherapy: Novel Combinations for a Specific Delivery.

Published in:

ChemMedChem, 2021, v. 16, n. 11, p. 1764, doi. 10.1002/cmdc.202100046

By:

Cerón‐Carrasco, José P.;
Jacquemin, Denis

Publication type:

Article

The European Federation for Medicinal Chemistry and Chemical Biology (EFMC) Best Practice Initiative: Phenotypic Drug Discovery.

Published in:

ChemMedChem, 2021, v. 16, n. 11, p. 1736, doi. 10.1002/cmdc.202100041

By:

Quancard, Jean;
Bach, Anders;
Cox, Brian;
Craft, Russell;
Finsinger, Dirk;
Guéret, Stéphanie M.;
Hartung, Ingo V.;
Laufer, Stefan;
Messinger, Josef;
Sbardella, Gianluca;
Koolman, Hannes F.

Publication type:

Article

Strategies towards Targeting Gαi/s Proteins: Scanning of Protein‐Protein Interaction Sites To Overcome Inaccessibility.

Published in:

ChemMedChem, 2021, v. 16, n. 11, p. 1696, doi. 10.1002/cmdc.202100039

By:

Nubbemeyer, Britta;
Pepanian, Anna;
Paul George, Ajay Abisheck;
Imhof, Diana

Publication type:

Article

Synthesis of Triphenylethylene‐Naphthalimide Conjugates as topoisomerase‐IIα inhibitor and HSA binder.

Published in:

ChemMedChem, 2021, v. 16, n. 11, p. 1821, doi. 10.1002/cmdc.202100034

By:

Rani, Sudesh;
Luxami, Vijay;
Paul, Kamaldeep

Publication type:

Article

A "Golden Age" for the discovery of new antileishmanial agents: Current status of leishmanicidal gold complexes and prospective targets beyond the trypanothione system.

Published in:

ChemMedChem, 2021, v. 16, n. 11, p. 1681, doi. 10.1002/cmdc.202100022

By:

Rosa, Leticia B.;
Aires, Rochanna L.;
Oliveira, Laiane S.;
Fontes, Josielle V.;
Miguel, Danilo C.;
Abbehausen, Camilla

Publication type:

Article

Drimane Derivatives as the First Examples of Covalent BH3 Mimetics that Target MCL‐1.

Published in:

ChemMedChem, 2021, v. 16, n. 11, p. 1788, doi. 10.1002/cmdc.202100011

By:

Daressy, Florian;
Malard, Florian;
Seguy, Line;
Guérineau, Vincent;
Apel, Cécile;
Dumontet, Vincent;
Robert, Aude;
Groo, Anne‐Claire;
Litaudon, Marc;
Bignon, Jérôme;
Desrat, Sandy;
Malzert‐Fréon, Aurélie;
Wiels, Joëlle;
Lescop, Ewen;
Roussi, Fanny

Publication type:

Article

Oxa Analogues of Nexturastat A Demonstrate Improved HDAC6 Selectivity and Superior Antileukaemia Activity.

Published in:

ChemMedChem, 2021, v. 16, n. 11, p. 1798, doi. 10.1002/cmdc.202001011

By:

Pflieger, Marc;
Sönnichsen, Melf;
Horstick‐Muche, Nadine;
Yang, Jing;
Schliehe‐Diecks, Julian;
Schöler, Andrea;
Borkhardt, Arndt;
Hamacher, Alexandra;
Kassack, Matthias U.;
Hansen, Finn K.;
Bhatia, Sanil;
Kurz, Thomas

Publication type:

Article

The Acid/Base Characterization of Molecules with Epigenetic Activity.

Published in:

ChemMedChem, 2021, v. 16, n. 11, p. 1744, doi. 10.1002/cmdc.202001009

By:

Santibáñez‐Morán, Marisa G.;
Medina‐Franco, José L.

Publication type:

Article

Development of a High‐Affinity Antibody‐Binding Peptide for Site‐Specific Modification.

Published in:

ChemMedChem, 2021, v. 16, n. 11, p. 1813, doi. 10.1002/cmdc.202000977

By:

Muguruma, Kyohei;
Osawa, Rento;
Fukuda, Akane;
Ishikawa, Naoto;
Fujita, Konomi;
Taguchi, Akihiro;
Takayama, Kentaro;
Taniguchi, Atsuhiko;
Ito, Yuji;
Hayashi, Yoshio

Publication type:

Article

Assessment of CYP2C9 Structural Models for Site of Metabolism Prediction.

Published in:

ChemMedChem, 2021, v. 16, n. 11, p. 1754, doi. 10.1002/cmdc.202000964

By:

Zhang, Xiaoxiao;
Xu, Minjie;
Wu, Zengrui;
Liu, Guixia;
Tang, Yun;
Li, Weihua

Publication type:

Article