Works matching IS 18607179 AND DT 2021 AND VI 16 AND IP 6

Results: 15

Front Cover: Synthesis and Structure−Activity Relationships of Imidazopyridine/Pyrimidine‐ and Furopyridine‐Based Anti‐infective Agents against Trypanosomiases (6/2021).

Published in:

ChemMedChem, 2021, v. 16, n. 6, p. 898, doi. 10.1002/cmdc.202100141

By:

G. Silva, Daniel;
Junker, Anna;
M. G. de Melo, Shaiani;
Fumagalli, Fernando;
Robert Gillespie, J.;
Molasky, Nora;
S. Buckner, Frederick;
Matheeussen, An;
Caljon, Guy;
Maes, Louis;
S. Emery, Flavio

Publication type:

Article

A Quick Route to Multiple Highly Potent SARS‐CoV‐2 Main Protease Inhibitors*.

Published in:

ChemMedChem, 2021, v. 16, n. 6, p. 942, doi. 10.1002/cmdc.202000924

By:

Yang, Kai S.;
Ma, Xinyu R.;
Ma, Yuying;
Alugubelli, Yugendar R.;
Scott, Danielle A.;
Vatansever, Erol C.;
Drelich, Aleksandra K.;
Sankaran, Banumathi;
Geng, Zhi Z.;
Blankenship, Lauren R.;
Ward, Hannah E.;
Sheng, Yan J.;
Hsu, Jason C.;
Kratch, Kaci C.;
Zhao, Baoyu;
Hayatshahi, Hamed S.;
Liu, Jin;
Li, Pingwei;
Fierke, Carol A.;
Tseng, Chien‐Te K.

Publication type:

Article

The tale of proteolysis targeting chimeras (PROTACs) for Leucine‐Rich Repeat Kinase 2 (LRRK2).

Published in:

ChemMedChem, 2021, v. 16, n. 6, p. 959, doi. 10.1002/cmdc.202000872

By:

Konstantinidou, Markella;
Oun, Asmaa;
Pathak, Pragya;
Zhang, Bidong;
Wang, Zefeng;
ter Brake, Frans;
Dolga, Amalia M.;
Kortholt, Arjan;
Dömling, Alexander

Publication type:

Article

Identification of Novel Fragments Binding to the PDZ1‐2 Domain of PSD‐95.

Published in:

ChemMedChem, 2021, v. 16, n. 6, p. 949, doi. 10.1002/cmdc.202000865

By:

Zang, Jie;
Ye, Fei;
Solbak, Sara M. Ø.;
Høj, Lars J.;
Zhang, Mingjie;
Bach, Anders

Publication type:

Article

Novel Pyridine‐Based Hydroxamates and 2′‐Aminoanilides as Histone Deacetylase Inhibitors: Biochemical Profile and Anticancer Activity.

Published in:

ChemMedChem, 2021, v. 16, n. 6, p. 989, doi. 10.1002/cmdc.202000854

By:

Zwergel, Clemens;
Di Bello, Elisabetta;
Fioravanti, Rossella;
Conte, Mariarosaria;
Nebbioso, Angela;
Mazzone, Roberta;
Brosch, Gerald;
Mercurio, Ciro;
Varasi, Mario;
Altucci, Lucia;
Valente, Sergio;
Mai, Antonello

Publication type:

Article

Inhibitors Targeting STAT5 Signaling in Myeloid Leukemias: New Tetrahydroquinoline Derivatives with Improved Antileukemic Potential.

Published in:

ChemMedChem, 2021, v. 16, n. 6, p. 1034, doi. 10.1002/cmdc.202000841

By:

Polomski, Marion;
Brachet‐Botineau, Marie;
Juen, Ludovic;
Viaud‐Massuard, Marie‐Claude;
Gouilleux, Fabrice;
Prié, Gildas

Publication type:

Article

Theranostics Through the Synergistic Cooperation of Heterometallic Complexes.

Published in:

ChemMedChem, 2021, v. 16, n. 6, p. 932, doi. 10.1002/cmdc.202000833

By:

Redrado, Marta;
Fernández‐Moreira, Vanesa;
Gimeno, M. Concepción

Publication type:

Article

Stimuli‐Responsive Nanomaterials for Smart Tumor‐Specific Phototherapeutics.

Published in:

ChemMedChem, 2021, v. 16, n. 6, p. 919, doi. 10.1002/cmdc.202000831

By:

Zhou, Bo;
Guo, Zhengxi;
Lin, Zhaoxin;
Jiang, Bang‐Ping;
Shen, Xing‐Can

Publication type:

Article

Heteroaromatic Inhibitors of the Astacin Proteinases Meprin α, Meprin β and Ovastacin Discovered by a Scaffold‐Hopping Approach.

Published in:

ChemMedChem, 2021, v. 16, n. 6, p. 976, doi. 10.1002/cmdc.202000822

By:

Tan, Kathrin;
Jäger, Christian;
Körschgen, Hagen;
Geissler, Stefanie;
Schlenzig, Dagmar;
Buchholz, Mirko;
Stöcker, Walter;
Ramsbeck, Daniel

Publication type:

Article

Explicit Treatment of Non‐Michaelis‐Menten and Atypical Kinetics in Early Drug Discovery*.

Published in:

ChemMedChem, 2021, v. 16, n. 6, p. 899, doi. 10.1002/cmdc.202000791

By:

Srinivasan, Bharath

Publication type:

Article

Design and Synthesis of DDR1 Inhibitors with a Desired Pharmacophore Using Deep Generative Models.

Published in:

ChemMedChem, 2021, v. 16, n. 6, p. 955, doi. 10.1002/cmdc.202000786

By:

Yoshimori, Atsushi;
Asawa, Yasunobu;
Kawasaki, Enzo;
Tasaka, Tomohiko;
Matsuda, Seiji;
Sekikawa, Toru;
Tanabe, Satoshi;
Neya, Masahiro;
Natsugari, Hideaki;
Kanai, Chisato

Publication type:

Article

Development of an Improved Guanidine‐Based Rac1 Inhibitor with in vivo Activity against Non‐Small Cell Lung Cancer.

Published in:

ChemMedChem, 2021, v. 16, n. 6, p. 1011, doi. 10.1002/cmdc.202000763

By:

Ciarlantini, Matías S.;
Barquero, Andrea;
Bayo, Juan;
Wetzler, Diana;
Dodes Traian, Martín M.;
Bucci, Hernán A.;
Fiore, Esteban J.;
Gandolfi Donadío, Lucía;
Defelipe, Lucas;
Turjanski, Adrián;
Ramírez, Javier A.;
Mazzolini, Guillermo;
Comin, Maria J.

Publication type:

Article

Synthesis and Biological Evaluation of 10‐Substituted Camptothecin Derivatives with Improved Water Solubility and Activity.

Published in:

ChemMedChem, 2021, v. 16, n. 6, p. 1000, doi. 10.1002/cmdc.202000753

By:

Yang, Xue‐Yan;
Zhao, Hong‐Yi;
Lei, Hao;
Yuan, Bo;
Mao, Shuai;
Xin, Minghang;
Zhang, San‐Qi

Publication type:

Article

Synthesis of Hydroxylated Biphenyl Derivatives Bearing an α,β‐Unsaturated Ketone as a Lead Structure for the Development of Drug Candidates against Malignant Melanoma.

Published in:

ChemMedChem, 2021, v. 16, n. 6, p. 1022, doi. 10.1002/cmdc.202000709

By:

Dettori, Maria Antonietta;
Pisano, Marina;
Rozzo, Carla;
Delogu, Giovanna;
Fabbri, Davide

Publication type:

Article

Synthesis and Structure−Activity Relationships of Imidazopyridine/Pyrimidine‐ and Furopyridine‐Based Anti‐infective Agents against Trypanosomiases.

Published in:

ChemMedChem, 2021, v. 16, n. 6, p. 966, doi. 10.1002/cmdc.202000616

By:

Silva, Daniel G.;
Junker, Anna;
Melo, Shaiani M. G.;
Fumagalli, Fernando;
Gillespie, J. Robert;
Molasky, Nora;
Buckner, Frederick S.;
Matheeussen, An;
Caljon, Guy;
Maes, Louis;
Emery, Flavio S.

Publication type:

Article