Works matching IS 18607179 AND DT 2021 AND VI 16 AND IP 7

Results: 15

Phenotypic Discovery of SB1501, an Anti‐obesity Agent, through Modulating Mitochondrial Activity.

Published in:

ChemMedChem, 2021, v. 16, n. 7, p. 1104, doi. 10.1002/cmdc.202100062

By:

Jo, Ala;
Kim, Mingi;
Kim, Jong In;
Ha, Jaeyoung;
Hwang, Yoon Soo;
Nam, Hyunsung;
Hwang, Injae;
Kim, Jae Bum;
Park, Seung Bum

Publication type:

Article

Front Cover: Improving Antibody‐Tubulysin Conjugates through Linker Chemistry and Site‐Specific Conjugation (ChemMedChem 7/2021).

Published in:

ChemMedChem, 2021, v. 16, n. 7, p. 1047, doi. 10.1002/cmdc.202100185

By:

Hamilton, Joseph Z.;
Pires, Thomas A.;
Mitchell, Jamie A.;
Cochran, Julia H.;
Emmerton, Kim K.;
Zaval, Margo;
Stone, Ivan J.;
Anderson, Martha E.;
Jin, Steven;
Waight, Andrew B.;
Lyon, Robert P.;
Senter, Peter D.;
Jeffrey, Scott C.;
Burke, Patrick J.

Publication type:

Article

Rational Design and Synthesis of Selective PRMT4 Inhibitors: A New Chemotype for Development of Cancer Therapeutics**.

Published in:

ChemMedChem, 2021, v. 16, n. 7, p. 1116, doi. 10.1002/cmdc.202100018

By:

Sutherland, Mathew;
Li, Alice;
Kaghad, Anissa;
Panagopoulos, Dimitrios;
Li, Fengling;
Szewczyk, Magdalena;
Smil, David;
Scholten, Cora;
Bouché, Léa;
Stellfeld, Timo;
Arrowsmith, Cheryl H.;
Barsyte, Dalia;
Vedadi, Masoud;
Hartung, Ingo V.;
Steuber, Holger;
Britton, Robert;
Santhakumar, Vijayaratnam

Publication type:

Article

Matrix Metalloproteinase 13 Inhibitors for Modulation of Osteoclastogenesis: Enhancement of Solubility and Stability.

Published in:

ChemMedChem, 2021, v. 16, n. 7, p. 1133, doi. 10.1002/cmdc.202000911

By:

Knapinska, Anna M.;
Singh, Chandani;
Drotleff, Gary;
Blanco, Daniela;
Chai, Cedric;
Schwab, Jason;
Herd, Anu;
Fields, Gregg B.

Publication type:

Article

Structure‐Based Drug Design of Phenazopyridine Derivatives as Inhibitors of Rev1 Interactions in Translesion Synthesis.

Published in:

ChemMedChem, 2021, v. 16, n. 7, p. 1126, doi. 10.1002/cmdc.202000893

By:

McPherson, Kerry Silva;
Zaino, Angela M.;
Dash, Radha C.;
Rizzo, Alessandro A.;
Li, Yunfeng;
Hao, Bing;
Bezsonova, Irina;
Hadden, M. Kyle;
Korzhnev, Dmitry M.

Publication type:

Article

Improving Antibody‐Tubulysin Conjugates through Linker Chemistry and Site‐Specific Conjugation.

Published in:

ChemMedChem, 2021, v. 16, n. 7, p. 1077, doi. 10.1002/cmdc.202000889

By:

Hamilton, Joseph Z.;
Pires, Thomas A.;
Mitchell, Jamie A.;
Cochran, Julia H.;
Emmerton, Kim K.;
Zaval, Margo;
Stone, Ivan J.;
Anderson, Martha E.;
Jin, Steven;
Waight, Andrew B.;
Lyon, Robert P.;
Senter, Peter D.;
Jeffrey, Scott C.;
Burke, Patrick J.

Publication type:

Article

Scanning Protein Surfaces with DNA‐Encoded Libraries.

Published in:

ChemMedChem, 2021, v. 16, n. 7, p. 1048, doi. 10.1002/cmdc.202000869

By:

Kunig, Verena B. K.;
Potowski, Marco;
Klika Škopić, Mateja;
Brunschweiger, Andreas

Publication type:

Article

Synthesis of σ Receptor Ligands with a Spirocyclic System Connected with a Tetrahydroisoquinoline Moiety via Different Linkers.

Published in:

ChemMedChem, 2021, v. 16, n. 7, p. 1184, doi. 10.1002/cmdc.202000861

By:

Bergkemper, Melanie;
Schepmann, Dirk;
Wünsch, Bernhard

Publication type:

Article

Systematic Assessment of Fragment Identification for Multitarget Drug Design.

Published in:

ChemMedChem, 2021, v. 16, n. 7, p. 1088, doi. 10.1002/cmdc.202000858

By:

Brunst, Steffen;
Kramer, Jan S.;
Kilu, Whitney;
Heering, Jan;
Pollinger, Julius;
Hiesinger, Kerstin;
George, Sven;
Steinhilber, Dieter;
Merk, Daniel;
Proschak, Ewgenij

Publication type:

Article

Dual‐Mechanism Quenched Fluorogenic Probe Provides Selective and Rapid Detection of Cathepsin L Activity**.

Published in:

ChemMedChem, 2021, v. 16, n. 7, p. 1082, doi. 10.1002/cmdc.202000823

By:

Schleyer, Kelton A.;
Fetrow, Ben;
Zannes Fatland, Peter;
Liu, Jun;
Chaaban, Maya;
Ma, Biwu;
Cui, Lina

Publication type:

Article

Synthesis of New Tyrosol‐Based Phosphodiester Derivatives: Effect on Amyloid β Aggregation and Metal Chelation Ability.

Published in:

ChemMedChem, 2021, v. 16, n. 7, p. 1172, doi. 10.1002/cmdc.202000807

By:

Romanucci, Valeria;
Giordano, Maddalena;
De Tommaso, Gaetano;
Iuliano, Mauro;
Bernini, Roberta;
Clemente, Mariangela;
Garcia‐Viñuales, Sara;
Milardi, Danilo;
Zarrelli, Armando;
Di Fabio, Giovanni

Publication type:

Article

Experimental Methods for Evaluating the Bacterial Uptake of Trojan Horse Antibacterials.

Published in:

ChemMedChem, 2021, v. 16, n. 7, p. 1063, doi. 10.1002/cmdc.202000806

By:

Southwell, James W.;
Black, Conor M.;
Duhme‐Klair, Anne‐Kathrin

Publication type:

Article

Identification of Phenazine‐Based MEMO1 Small‐Molecule Inhibitors: Virtual Screening, Fluorescence Polarization Validation, and Inhibition of Breast Cancer Migration.

Published in:

ChemMedChem, 2021, v. 16, n. 7, p. 1163, doi. 10.1002/cmdc.202000797

By:

Labrecque, Courtney L.;
Hilton, Cassidy N.;
Airas, Justin;
Blake, Alexis;
Rubenstein, Kristen J.;
Parish, Carol A.;
Pollock, Julie A.

Publication type:

Article

Discovery of Halogenated Benzothiadiazine Derivatives with Anticancer Activity**.

Published in:

ChemMedChem, 2021, v. 16, n. 7, p. 1143, doi. 10.1002/cmdc.202000729

By:

Huwaimel, Bader I.;
Bhakta, Myla;
Kulkarni, Chaitanya A.;
Milliken, Alexander S.;
Wang, Feifei;
Peng, Aimin;
Brookes, Paul S.;
Trippier, Paul C.

Publication type:

Article

Artificial Intelligence Applied to the Rapid Identification of New Antimalarial Candidates with Dual‐Stage Activity.

Published in:

ChemMedChem, 2021, v. 16, n. 7, p. 1093, doi. 10.1002/cmdc.202000685

By:

Lima, Marilia N. N.;
Borba, Joyce V. B.;
Cassiano, Gustavo C.;
Mottin, Melina;
Mendonça, Sabrina S.;
Silva, Arthur C.;
Tomaz, Kaira C. P.;
Calit, Juliana;
Bargieri, Daniel Y.;
Costa, Fabio T. M.;
Andrade, Carolina H.

Publication type:

Article