Works matching DE "PHARMACEUTICAL chemistry"

Results: 5000

Structure-based design of potent and selective inhibitors of the HECT ligase NEDD4.

Published in:

Communications Chemistry, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42004-025-01557-4

By:

Maspero, Elena;
Cappa, Anna;
Weber, Janine;
Trifirò, Paolo;
Amici, Raffaella;
Bruno, Agostino;
Fagà, Giovanni;
Cecatiello, Valentina;
Fattori, Raimondo;
Leuzzi, Brian;
Taibi, Vincenzo;
Meroni, Giuseppe;
Pasi, Maurizio;
Romussi, Alessia;
Sartori, Luca;
Villa, Manuela;
Vultaggio, Stefania;
Cirò, Marco;
Soffientini, Paolo;
Lombardo, Lierin

Publication type:

Article

Efficient Synthesis of Tetrasubstituted Furans via Lipase-Catalyzed One-Pot Sequential Multicomponent Reaction.

Published in:

Catalysts (2073-4344), 2025, v. 15, n. 5, p. 482, doi. 10.3390/catal15050482

By:

Zeng, Yongqi;
Tang, Yong;
Xu, Minglu;
Wang, Dantong;
Wang, Zhi;
Gao, Yin;
Wang, Lei

Publication type:

Article

Recent Advances in the Synthesis of Quinolines: A Focus on Oxidative Annulation Strategies.

Published in:

Catalysts (2073-4344), 2025, v. 15, n. 5, p. 441, doi. 10.3390/catal15050441

By:

Liao, Mao-Lin;
Liu, Peng-Peng;
Yang, Jia-Cheng;
Li, Ping-Gui;
Zou, Liang-Hua

Publication type:

Article

Unveiling the Reaction Pathway of Oxidative Aldehyde Deformylation by a MOF-Based Cytochrome P450 Mimic.

Published in:

Catalysts (2073-4344), 2025, v. 15, n. 5, p. 436, doi. 10.3390/catal15050436

By:

Luo, Zehua;
Zhou, Wentian;
Chen, Junying;
Li, Yingwei

Publication type:

Article

Illuminating innovation: the AAPS Open editorial series of AAPS fellows and awardees.

Published in:

2025

By:

Su, Yongchao;
Ronaldson, Patrick;
Kumar, M. N. V. Ravi

Publication type:

Editorial

Nanoparticles and Nanomaterials: A Review from the Standpoint of Pharmacy and Medicine.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 655, doi. 10.3390/pharmaceutics17050655

By:

Petrov, Gleb V.;
Koldina, Alena M.;
Ledenev, Oleg V.;
Tumasov, Vladimir N.;
Nazarov, Aleksandr A.;
Syroeshkin, Anton V.

Publication type:

Article

Self-Assembled Cannabigerol-Based Nanoparticles: Design, Synthesis, and Antiproliferative Activity.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 636, doi. 10.3390/pharmaceutics17050636

By:

Amenta, Arianna;
Nordio, Giulia;
Piazzola, Francesco;
Di Paolo, Maria Luisa;
Milani, Fabio;
Giacomini, Martina;
Citarella, Andrea;
Ciriello, Umberto;
Paladino, Giuseppe;
Pellegrino, Sara;
Silvestri, Federica;
Fasano, Valerio;
Dalla Via, Lisa;
Passarella, Daniele

Publication type:

Article

From Patterns to Pills: How Informatics Is Shaping Medicinal Chemistry.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 612, doi. 10.3390/pharmaceutics17050612

By:

Trachtenberg, Alexander;
Akabayov, Barak

Publication type:

Article

Medicinal Chemistry Strategies in Targeting TGF-βR1 Kinase Domain: Unveiling Insights into Inhibitor Structure–Activity Relationship (SAR).

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 5, p. 716, doi. 10.3390/ph18050716

By:

Babiker, Nusaiba A.;
Nadeem, Soam;
Abu Kariem, Hasan;
Abdul Hameed, Afra;
Negmeldin, Ahmed T.;
El-labbad, Eman M.

Publication type:

Article

Nitropyridines in the Synthesis of Bioactive Molecules.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 5, p. 692, doi. 10.3390/ph18050692

By:

Starosotnikov, Alexey;
Bastrakov, Maxim

Publication type:

Article

Beyond Exosomes: An Ultrapurified Phospholipoproteic Complex (PLPC) as a Scalable Immunomodulatory Platform for Reprogramming Immune Suppression in Metastatic Cancer.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1658, doi. 10.3390/cancers17101658

By:

Gutierrez-Sandoval, Ramon;
Gutiérrez-Castro, Francisco;
Muñoz-Godoy, Natalia;
Rivadeneira, Ider;
Sobarzo, Adolay;
Iturra, Jordan;
Krakowiak, Francisco;
Alarcón, Luis;
Dorado, Wilson;
Lagos, Andy;
Montenegro, Diego;
Muñoz, Ignacio;
Aguilera, Rodrigo;
Toledo, Andres

Publication type:

Article

Gum Rosin in Medical and Pharmaceutical Applications: From Conventional Uses to Modern Advancements.

Published in:

Materials (1996-1944), 2025, v. 18, n. 10, p. 2266, doi. 10.3390/ma18102266

By:

Siboro, Sonita Afrita Purba;
Salma, Sabrina Aufar;
Syuhada;
Putri, Kurnia Sari Setio;
Yuliati, Frita;
Lee, Won-Ki;
Lim, Kwon-Taek

Publication type:

Article

Recent Developments and Perspectives in Palladium‐Catalyzed Multi‐Component Reactions.

Published in:

European Journal of Organic Chemistry, 2025, v. 28, n. 19, p. 1, doi. 10.1002/ejoc.202401429

By:

Rinu, Pulluparambil Xavier Thresia;
Saranya, Salim;
Anilkumar, Gopinathan

Publication type:

Article

Extended Family of Thiophosphoryl-Appended Pd(II) Pincer Complexes with a Deprotonated Amide Core: Synthesis and Biological Evaluation.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4536, doi. 10.3390/ijms26104536

By:

Aleksanyan, Diana V.;
Churusova, Svetlana G.;
Konovalov, Aleksandr V.;
Rybalkina, Ekaterina Yu.;
Laletina, Lidia A.;
Ryzhmanova, Yana V.;
Nelyubina, Yulia V.;
Soloveva, Svetlana A.;
Lyubimov, Sergey E.;
Peregudov, Alexander S.;
Klemenkova, Zinaida S.;
Kozlov, Vladimir A.

Publication type:

Article

Vanadium 8-hydroxyquinoline derivatives in medicine: current state and future outlook.

Published in:

BioMetals, 2025, v. 38, n. 3, p. 711, doi. 10.1007/s10534-025-00683-9

By:

Kohanfekr, Tahmineh;
Gholamrezazadeh, Camelia;
Hosseini, Hasan Ali

Publication type:

Article

Integrated bioinformatics and network pharmacology to identify and validate macrophage polarization related hub genes in the treatment of osteoarthritis with Astragalus membranaceus.

Published in:

Journal of Orthopaedic Surgery & Research, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13018-025-05799-9

By:

Zang, Hui;
Wang, Liuyan;
Wu, Yang;
Chang, Junfei;
Liu, Wanjun

Publication type:

Article

Investigating inspection practices of pharmaceutical manufacturing facilities in selected Arab countries: views of inspectors and pharmaceutical industry employees.

Published in:

Eastern Mediterranean Health Journal, 2013, v. 19, n. 11, p. 919, doi. 10.26719/2013.19.11.919

By:

Garg, S.;
Hasan, R.;
Scahill, S.;
Babar, Z. Ud-Din

Publication type:

Article

Molecular mechanism of Codonopsis pilosula in the prevention and treatment of immune thrombocytopenia based on network pharmacology and molecular docking.

Published in:

Chinese Nursing Research, 2024, v. 38, n. 9, p. 1505, doi. 10.12102/j.issn.1009-6493.2024.09.001

By:

ZHU Ruifang;
CHEN Yulu;
WANG Qian;
ZHANG Jun;
ZHANG Shuwen;
LYU Yaru;
HAN Shifan;
WANG Hongwei

Publication type:

Article

GD2抗体达妥昔单抗β 治疗神经母细胞瘤护理专家共识.

Published in:

Chinese Nursing Research, 2024, v. 38, n. 6, p. 941, doi. 10.12102/j.issn.1009-6493.2024.06.001

By:

王春立;
武莹;
何梦雪;
苏玲;
张洪燕;
郭欣;
程方方;
李丹;
孙丹;
王翠

Publication type:

Article

基于网络药理学和分子对接技术探讨沙棘活性成分对非酒精性脂肪肝作用机制

Published in:

Chinese Nursing Research, 2023, v. 37, n. 16, p. 2853, doi. 10.12102/j.issn.1009-6493.2023.16.001

By:

高健;
吴胜男;
王晓静;
纪景馨;
张然;
程景民

Publication type:

Article

Think Twice Before Prescribing Custom-Compounded Bioidentical Hormone Therapy.

Published in:

2014

By:

Pinkerton, JoAnn V.

Publication type:

Journal Article

Risks and Effectiveness of Compounded Bioidentical Hormone Therapy: A Case Series.

Published in:

2014

By:

Davis, Ruth;
Batur, Pelin;
Thacker, Holly L

Publication type:

Journal Article

High Throughput Screening Retools for the Future.

Published in:

Bio-IT World, 2009, v. 8, n. 1, p. 20

By:

Glaser, Vicki

Publication type:

Article

THE SEARCH FOR Unusual Suspects.

Published in:: Bio-IT World, 2008, v. 7, n. 1, p. 26
Publication type:: Article

Software Solutions for MEDICINAL CHEMISTRY.

Published in:

Bio-IT World, 2007, v. 6, n. 3, p. 22

By:

Glaser, Vicki

Publication type:

Article

The Galileo Code.

Published in:

Bio-IT World, 2005, v. 4, n. 2, p. 24

By:

Davies, Kevin

Publication type:

Article

Tackling ADME/Tox Workflow.

Published in:

Bio-IT World, 2005, v. 4, n. 2, p. 18

By:

Salamone, Salvatore

Publication type:

Article

How to Find a New TB Drug.

Published in:

Bio-IT World, 2005, v. 4, n. 1, p. 17

By:

Uehling, Mark D.

Publication type:

Article

Beckman Coulter Displays Affinity for Multi-Mode HTS.

Published in:: 2003
Publication type:: Product Review

Diversification of Simple Arenes into Complex (Amino)cyclitols.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 6, p. 1, doi. 10.1002/chem.202303262

By:

Angelini, Elisa;
Martinelli, Matteo;
Roà, Eugenio;
Ungarean, Chad N.;
Salome, Christophe;
Lefebvre, Quentin;
Bournez, Colin;
Fessard, Thomas C.;
Sarlah, David

Publication type:

Article

Copper‐Mediated N‐Trifluoromethylation of O‐Benzoylhydroxylamines.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 6, p. 1, doi. 10.1002/chem.202303314

By:

Fleetwood, Thomas D.;
Kerr, William J.;
Mason, Joseph

Publication type:

Article

Photo‐Induced C−H Methylation Reactions.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 72, p. 1, doi. 10.1002/chem.202302542

By:

Li, Qian‐Yu;
He, Yuhang;
Lin, Yu‐Mei;
Gong, Lei

Publication type:

Article

Late‐Stage C−H Activation of Drug (Derivative) Molecules with Pd(ll) Catalysis.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 71, p. 1, doi. 10.1002/chem.202302620

By:

Shim, Su Yong

Publication type:

Article

Highly Enantioselective Synthesis of Pharmaceuticals at Chiral‐Encoded Metal Surfaces.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 61, p. 1, doi. 10.1002/chem.202302054

By:

Somsri, Supattra;
Suwankaisorn, Banyong;
Yomthong, Krissanapat;
Srisuwanno, Wanmai;
Klinyod, Sorasak;
Kuhn, Alexander;
Wattanakit, Chularat

Publication type:

Article

Determination of the Handedness of Urea Inclusion Compounds.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 59, p. 1, doi. 10.1002/chem.202302217

By:

Wang, Bo;
Xu, Chaofan;
Liang, Wenli;
Pongkulapa, Pasaorn;
Lin, Yiqing

Publication type:

Article

The Role of Inverted Ligand Field in the Electronic Structure and Reactivity of Octahedral Formal Platinum (IV) Complexes**.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 59, p. 1, doi. 10.1002/chem.202301669

By:

Ienco, Andrea;
Ruffo, Francesco;
Manca, Gabriele

Publication type:

Article

Gold(I)‐N‐Heterocyclic Carbene Synthons in Organometallic Synthesis.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 58, p. 1, doi. 10.1002/chem.202301961

By:

Scattolin, Thomas;
Tonon, Giovanni;
Botter, Eleonora;
Guillet, Sebastien G.;
Tzouras, Nikolaos V.;
Nolan, Steven P.

Publication type:

Article

Hydrofluorination of Alkynes: From (E) to (Z).

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 58, p. 1, doi. 10.1002/chem.202301896

By:

Gauthier, Raphaël;
Paquin, Jean‐François

Publication type:

Article

Next Generation of Fluorometric Protease Assays: 7‐Nitrobenz‐2‐oxa‐1,3‐diazol‐4‐yl‐amides (NBD‐Amides) as Class‐Spanning Protease Substrates.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 50, p. 1, doi. 10.1002/chem.202301855

By:

Maus, Hannah;
Müller, Patrick;
Meta, Mergim;
Hoba, Sabrina N.;
Hammerschmidt, Stefan J.;
Zimmermann, Robert A.;
Zimmer, Collin;
Fuchs, Natalie;
Schirmeister, Tanja;
Barthels, Fabian

Publication type:

Article

Synthesis and Biological Evaluation of Simplified Ansellone Analogues with Lipophilic Side Chains as HIV Latency‐Reversing Agents.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 44, p. 1, doi. 10.1002/chem.202300677

By:

Yanagihara, Mizushi;
Kishimoto, Naoki;
Nakahara, Kanae;
Abe, Towa;
Miura, Satoshi;
Lin, Bangzhong;
Fumimoto, Megumi;
Haruta, Junichi;
Misumi, Shogo;
Arisawa, Mitsuhiro;
Murai, Kenichi

Publication type:

Article

A Mild Synthesis of Aryl Triflates Enabling the Late‐Stage Modification of Drug Analogs and Complex Peptides.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 42, p. 1, doi. 10.1002/chem.202301421

By:

Schiesser, Stefan;
Ceklarz, Joanna;
Kollback, Johanna;
Borowiec, Lucie;
Fagerlund, Julia;
Vahdat, Shakiba;
Lindhagen, Marika;
Dwichandra Putra, Okky

Publication type:

Article

De‐Novo Design of pre‐miR‐21 Maturation Inhibitors: Synthesis and Activity Assessment.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 40, p. 1, doi. 10.1002/chem.202300825

By:

Shcheholeva, Iryna;
Fernández‐Remacha, Daniel;
Estrada‐Tejedor, Roger;
Duca, Maria;
Michelet, Véronique

Publication type:

Article

Cover Feature: Synthesis and Structure‐Activity Relationship Studies of C(13)‐Desmethylene‐(−)‐Zampanolide Analogs (Chem. Eur. J. 36/2023).

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 36, p. 1, doi. 10.1002/chem.202301652

By:

Brütsch, Tobias M.;
Cotter, Etienne;
Lucena‐Agell, Daniel;
Redondo‐Horcajo, Mariano;
Davies, Carolina;
Pfeiffer, Bernhard;
Pagani, Sandro;
Berardozzi, Simone;
Fernando Díaz, J.;
Miller, John H.;
Altmann, Karl‐Heinz

Publication type:

Article

Iron‐Catalyzed Deoxynitrogenation of Carboxylic Acids with Cyanamides to Access Nitriles.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 31, p. 1, doi. 10.1002/chem.202300217

By:

Li, Mengsheng;
Zhang, Jing

Publication type:

Article

Frontispiece: Atroposelective Synthesis of Heterobiaryls through Ring Formation.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 27, p. 1, doi. 10.1002/chem.202382761

By:

Sun, Huai‐Ri;
Sharif, Atif;
Chen, Jie;
Zhou, Ling

Publication type:

Article

Diversification of Indoles and Pyrroles by Molecular Editing: New Frontiers in Heterocycle‐to‐Heterocycle Transmutation.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 24, p. 1, doi. 10.1002/chem.202300096

By:

Liu, Fernanda;
Anand, Lakshita;
Szostak, Michal

Publication type:

Article

Cover Feature: Optimization of the Lead Compound NVP‐BHG712 as a Colorectal Cancer Inhibitor (Chem. Eur. J. 23/2023).

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 23, p. 1, doi. 10.1002/chem.202300918

By:

Tröster, Alix;
DiPrima, Michael;
Jores, Nathalie;
Kudlinzki, Denis;
Sreeramulu, Sridhar;
Gande, Santosh L.;
Linhard, Verena;
Ludig, Damian;
Schug, Alexander;
Saxena, Krishna;
Reinecke, Maria;
Heinzlmeir, Stephanie;
Leisegang, Matthias S.;
Wollenhaupt, Jan;
Lennartz, Frank;
Weiss, Manfred S.;
Kuster, Bernhard;
Tosato, Giovanna;
Schwalbe, Harald

Publication type:

Article

The Aldol‐Tishchenko Reaction of Butanone, Cyclobutanone and a 3‐Pentanone Derived Sulfinylimine and DFT Calculations of the Stereo‐determining Step.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 22, p. 1, doi. 10.1002/chem.202203029

By:

Alcock, Emma;
Mackey, Pamela;
Turlik, Aneta;
Bhatt, Khushi;
Light, Mark E.;
Houk, Kendall N.;
McGlacken, Gerard P.

Publication type:

Article

Diastereoselectivity Switch During Alkene Reductions: Diastereodivergent Syntheses of Molecular Fossils via MHAT or Homogeneous Catalytic Hydrogenation Reactions.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 20, p. 1, doi. 10.1002/chem.202203731

By:

Maior, Christian R. S.;
Costa, Paulo C. S.;
Ligiéro, Carolina B. P.;
de Moraes, Lygia S.;
Sousa, Gustavo R.;
Lima, Sidney G.;
Esteves, Pierre M.;
Miranda, Paulo C. M. L.

Publication type:

Article

Carbotrifluoromethylations of C−C Multiple Bonds (Excluding Aryl‐ and Alkynyltrifluoromethylations).

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 19, p. 1, doi. 10.1002/chem.202203499

By:

Aradi, Klára;
Kiss, Loránd

Publication type:

Article