Transition‐Metal‐Catalyzed Addition of Organosulfur Compounds to Alkynes and Alkenes: Catalysis and Catalyst Poisons.

Yamamoto, Yuki; Ogawa, Akiya

The addition of heteroatom compounds to alkynes and alkenes is an atom‐efficient method of carbon‐heteroatom bond formation and is widely used as a fundamental synthetic method for the construction of functional molecules. Nevertheless, examples of transition‐metal‐catalyzed addition reactions of group 16 heteroatom compounds to carbon‐carbon unsaturated bonds have been limited due to the widespread belief that organic sulfur and selenium compounds are representative catalyst poisons. In recent decades, however, several seminal catalytic reactions of sulfur compounds have been developed, providing important insights into catalysis and poisons. Therefore, this paper focuses on the transition‐metal‐catalyzed addition of organosulfur compounds to alkynes and alkenes, gains comprehensive insights into the catalysis and catalyst poisons, and proposes concepts for the development of transition‐metal‐catalyzed reactions of group 16 heteroatom compounds.

CATALYST poisoning; ORGANOSULFUR compounds; TRANSITION metal catalysts; ORGANOCATALYSIS; ORGANOSELENIUM compounds; ALKYNES; ALKENES; SULFUR compounds

Chemistry - A European Journal, 2023, Vol 29, Issue 64, p1

0947-6539

Academic Journal

10.1002/chem.202302432