Works matching Jack W. Szostak

Results: 97

RNA‐Catalyzed RNA Ligation within Prebiotically Plausible Model Protocells.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 43, p. 1, doi. 10.1002/chem.202301376

By:

DasGupta, Saurja;
Zhang, Stephanie J.;
Smela, Merrick P.;
Szostak, Jack W.

Publication type:

Article

Electrostatic Localization of RNA to Protocell Membranes by Cationic Hydrophobic Peptides.

Published in:

Angewandte Chemie, 2015, v. 127, n. 40, p. 11901, doi. 10.1002/ange.201505742

By:

Kamat, Neha P.;
Tobé, Sylvia;
Hill, Ian T.;
Szostak, Jack W.

Publication type:

Article

Optimal Codon Choice Can Improve the Efficiency and Fidelity of N-Methyl Amino Acid Incorporation into Peptides by In-Vitro Translation.

Published in:

Angewandte Chemie, 2011, v. 123, n. 14, p. 3222, doi. 10.1002/ange.201007686

By:

Subtelny, Alexander O.;
Hartman, Matthew C. T.;
Szostak, Jack W.

Publication type:

Article

Construction of artificial chromosomes in yeast.

Published in:

Nature, 1983, v. 305, n. 5931, p. 189, doi. 10.1038/305189a0

By:

Murray, Andrew W.;
Szostak, Jack W.

Publication type:

Article

Is there left-handed DNA at the ends of yeast chromosomes?

Published in:

Nature, 1983, v. 302, n. 5903, p. 84, doi. 10.1038/302084a0

By:

Walmsley, Richard M.;
Szostak, Jack W.;
Petes, Thomas D.

Publication type:

Article

The Origin of Life on Earth and the Design of Alternative Life Forms.

Published in:

Molecular Frontiers Journal, 2017, v. 1, n. 2, p. 121, doi. 10.1142/S2529732517400132

By:

Szostak, Jack W.

Publication type:

Article

The eightfold path to non-enzymatic RNA replication.

Published in:

Journal of Systems Chemistry, 2012, v. 3, n. 1, p. 1, doi. 10.1186/1759-2208-3-2

By:

Szostak, Jack W.

Publication type:

Article

ON THE ORIGIN OF LIFE.

Published in:

Medicina (Buenos Aires), 2016, v. 76, n. 4, p. 199

By:

SZOSTAK, JACK W.

Publication type:

Article

Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging.

Published in:

Nature Medicine, 2006, v. 12, n. 10, p. 1133, doi. 10.1038/nm1006-1133

By:

Blackburn, Elizabeth H.;
Greider, Carol W.;
Szostak, Jack W.

Publication type:

Article

In search of the RNA world on Mars.

Published in:

Geobiology, 2021, v. 19, n. 3, p. 307, doi. 10.1111/gbi.12433

By:

Mojarro, Angel;
Jin, Lin;
Szostak, Jack W.;
Head, James W.;
Zuber, Maria T.

Publication type:

Article

Preparation of Large Monodisperse Vesicles.

Published in:

PLoS ONE, 2009, v. 4, n. 4, p. 1, doi. 10.1371/journal.pone.0005009

By:

Zhu, Ting F.;
Szostak, Jack W.

Publication type:

Article

Enzymatic Primer-Extension with Glycerol-Nucleoside Triphosphates on DNA Templates.

Published in:

PLoS ONE, 2009, v. 4, n. 3, p. 1, doi. 10.1371/journal.pone.0004949

By:

Chen, Jesse J.;
Ching-Hsuan Tsai;
Xin Cai;
Horhota, Allen T.;
McLaughlin, Larry W.;
Szostak, Jack W.

Publication type:

Article

Virtual Circular Genome Model for Prebiotically Plausible Nonenzymatic RNA Replication.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.0R822

By:

Ding, Dian;
Zhou, Lijun;
Szostak, Jack W.

Publication type:

Article

Selection of cyclic peptide aptamers to HCV IRES RNA using mRNA display.

Published in:

FASEB Journal, 2008, v. 22, p. 338, doi. 10.1096/fasebj.22.2_supplement.338

By:

Litovchick, Alexander;
Szostak, Jack W.

Publication type:

Article

Selective Nonenzymatic Formation of Biologically Common RNA Hairpins.

Published in:

Angewandte Chemie International Edition, 2025, v. 64, n. 5, p. 1, doi. 10.1002/anie.202417370

By:

Wu, Long‐Fei;
Zhang, Junting;
Cornwell‐Arquitt, Robert;
Hendrix, David A.;
Radakovic, Aleksandar;
Szostak, Jack W.

Publication type:

Article

Structure–Activity Relationships in Nonenzymatic Template‐Directed RNA Synthesis.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 42, p. 22925, doi. 10.1002/anie.202109714

By:

Giurgiu, Constantin;
Fang, Ziyuan;
Aitken, Harry R. M.;
Kim, Seohyun Chris;
Pazienza, Lydia;
Mittal, Shriyaa;
Szostak, Jack W.

Publication type:

Article

Evolution ex vivo.

Published in:

Nature, 1993, v. 361, n. 6408, p. 119, doi. 10.1038/361119a0

By:

Szostak, Jack W.

Publication type:

Article

The beginning of the ends.

Published in:

Nature, 1989, v. 337, n. 6205, p. 303, doi. 10.1038/337303a0

By:

Szostak, Jack W.

Publication type:

Article

Telomeric repeat from T. thermophila cross hybridizes with human telomeres.

Published in:

Nature, 1988, v. 332, n. 6165, p. 656, doi. 10.1038/332656a0

By:

Allshire, Robin C.;
Gosden, John R.;
Cross, Sally H.;
Cranston, Gwen;
Rout, Derek;
Sugawara, Neal;
Szostak, Jack W.;
Fantes, Peter A.;
Hastie, Nicholas D.

Publication type:

Article

Selective Nonenzymatic Formation of Biologically Common RNA Hairpins.

Published in:

Angewandte Chemie, 2025, v. 137, n. 5, p. 1, doi. 10.1002/ange.202417370

By:

Wu, Long‐Fei;
Zhang, Junting;
Cornwell‐Arquitt, Robert;
Hendrix, David A.;
Radakovic, Aleksandar;
Szostak, Jack W.

Publication type:

Article

Ribozyme-catalysed amino-acid transfer reactions.

Published in:

Nature, 1996, v. 381, n. 6581, p. 442, doi. 10.1038/381442a0

By:

Lohse, Peter A.;
Szostak, Jack W.

Publication type:

Article

A DNA metalloenzyme with DNA ligase activity.

Published in:

Nature, 1995, v. 375, n. 6532, p. 611, doi. 10.1038/375611a0

By:

Cuenoud, Bernard;
Szostak, Jack W.

Publication type:

Article

In vitro evolution of new ribozymes with polynucleotide kinase activity.

Published in:

Nature, 1994, v. 371, n. 6492, p. 31, doi. 10.1038/371031a0

By:

Lorsch, Jon R.;
Szostak, Jack W.

Publication type:

Article

An RNA motif that binds ATP.

Published in:

Nature, 1993, v. 364, n. 6437, p. 550, doi. 10.1038/364550a0

By:

Sassanfar, Mandana;
Szostak, Jack W.

Publication type:

Article

Ribozyme-catalyzed tRNA aminoacylation.

Published in:

Nature Structural Biology, 2000, v. 7, n. 1, p. 28

By:

Lee, Nick;
Bessho, Yoshitaka;
Wei, Kenneth;
Szostak, Jack W.;
Suga, Hiroaki

Publication type:

Article

In Vitro Selection of Specific Ligand-binding Nucleic Acids.

Published in:

Angewandte Chemie International Edition, 1992, v. 31, n. 8, p. 979, doi. 10.1002/anie.199209791

By:

Famulok, Michael;
Szostak, Jack W.

Publication type:

Article

Structure–Activity Relationships in Nonenzymatic Template‐Directed RNA Synthesis.

Published in:

Angewandte Chemie, 2021, v. 133, n. 42, p. 23107, doi. 10.1002/ange.202109714

By:

Giurgiu, Constantin;
Fang, Ziyuan;
Aitken, Harry R. M.;
Kim, Seohyun Chris;
Pazienza, Lydia;
Mittal, Shriyaa;
Szostak, Jack W.

Publication type:

Article

Template‐Directed Copying of RNA by Non‐enzymatic Ligation.

Published in:

Angewandte Chemie, 2020, v. 132, n. 36, p. 15812, doi. 10.1002/ange.202004934

By:

Zhou, Lijun;
O'Flaherty, Derek K.;
Szostak, Jack W.

Publication type:

Article

The Mechanism of Nonenzymatic Template Copying with Imidazole‐Activated Nucleotides.

Published in:

Angewandte Chemie, 2019, v. 131, n. 32, p. 10926, doi. 10.1002/ange.201902050

By:

Walton, Travis;
Zhang, Wen;
Li, Li;
Tam, Chun Pong;
Szostak, Jack W.

Publication type:

Article

A Fluorescent G‐Quadruplex Sensor for Chemical RNA Copying.

Published in:

Angewandte Chemie, 2018, v. 130, n. 31, p. 9992, doi. 10.1002/ange.201805785

By:

Giurgiu, Constantin;
Wright, Tom H.;
O'Flaherty, Derek K.;
Szostak, Jack W.

Publication type:

Article

Der schmale Pfad tief in die Vergangenheit: auf der Suche nach der Chemie der Anfänge des Lebens.

Published in:

Angewandte Chemie, 2017, v. 129, n. 37, p. 11182, doi. 10.1002/ange.201704048

By:

Szostak, Jack W.

Publication type:

Article

Functional information: Molecular messages.

Published in:

Nature, 2003, v. 423, n. 6941, p. 689, doi. 10.1038/423689a

By:

Szostak, Jack W.

Publication type:

Article

RNA gets a grip on translation.

Published in:

Nature, 2002, v. 419, n. 6910, p. 890, doi. 10.1038/419890a

By:

Szostak, Jack W.

Publication type:

Article

In vitro evolution suggests multiple origins for the hammerhead ribozyme.

Published in:

Nature, 2001, v. 414, n. 6859, p. 82, doi. 10.1038/35102081

By:

Salehi-Ashtiani, Kourosh;
Szostak, Jack W.

Publication type:

Article

Functional proteins from a random-sequence library.

Published in:

Nature, 2001, v. 410, n. 6829, p. 715, doi. 10.1038/35070613

By:

Keefe, Anthony D.;
Szostak, Jack W.

Publication type:

Article

Synthesizing life.

Published in:

Nature, 2001, v. 409, n. 6818, p. 387, doi. 10.1038/35053176

By:

Szostak, Jack W.;
Bartel, David P.;
Luisi, P. Luigi

Publication type:

Article

Overcoming nucleotide bias in the nonenzymatic copying of RNA templates.

Published in:

Nucleic Acids Research, 2024, n. 22, p. 13515, doi. 10.1093/nar/gkae982

By:

Duzdevich, Daniel;
Carr, Christopher E;
Colville, Ben W F;
Aitken, Harry R M;
Szostak, Jack W

Publication type:

Article

Constraints on the emergence of RNA through non-templated primer extension with mixtures of potentially prebiotic nucleotides.

Published in:

Nucleic Acids Research, 2024, v. 52, n. 10, p. 5451, doi. 10.1093/nar/gkae355

By:

Jia, Xiwen;
Zhang, Stephanie J;
Zhou, Lijun;
Szostak, Jack W

Publication type:

Article

Transient states during the annealing of mismatched and bulged oligonucleotides.

Published in:

Nucleic Acids Research, 2024, v. 52, n. 5, p. 2174, doi. 10.1093/nar/gkae091

By:

Todisco, Marco;
Ding, Dian;
Szostak, Jack W

Publication type:

Article

Enhanced nonenzymatic RNA copying with in-situ activation of short oligonucleotides.

Published in:

Nucleic Acids Research, 2023, v. 51, n. 13, p. 6528, doi. 10.1093/nar/gkad439

By:

Ding, Dian;
Zhang, Stephanie J;
Szostak, Jack W

Publication type:

Article

Hybridization kinetics of out-of-equilibrium mixtures of short RNA oligonucleotides.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 17, p. 9647, doi. 10.1093/nar/gkac784

By:

Todisco, Marco;
Szostak, Jack W

Publication type:

Article

Kinetic explanations for the sequence biases observed in the nonenzymatic copying of RNA templates.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 1, p. 35, doi. 10.1093/nar/gkab1202

By:

Ding, Dian;
Zhou, Lijun;
Giurgiu, Constantin;
Szostak, Jack W

Publication type:

Article

Competition between bridged dinucleotides and activated mononucleotides determines the error frequency of nonenzymatic RNA primer extension.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 7, p. 3681, doi. 10.1093/nar/gkab173

By:

Duzdevich, Daniel;
Carr, Christopher E;
Ding, Dian;
Zhang, Stephanie J;
Walton, Travis S;
Szostak, Jack W

Publication type:

Article

Structural interpretation of the effects of threo-nucleotides on nonenzymatic template-directed polymerization.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 2, p. 646, doi. 10.1093/nar/gkaa1215

By:

Zhang, Wen;
Kim, Seohyun Chris;
Tam, Chun Pong;
Lelyveld, Victor S;
Bala, Saikat;
Chaput, John C;
Szostak, Jack W

Publication type:

Article

Deep sequencing of non-enzymatic RNA primer extension.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 12, p. e70, doi. 10.1093/nar/gkaa400

By:

Duzdevich, Daniel;
Carr, Christopher E;
Szostak, Jack W

Publication type:

Article

DNA polymerase activity on synthetic N3′→P5′ phosphoramidate DNA templates.

Published in:

Nucleic Acids Research, 2019, v. 47, n. 17, p. 8941, doi. 10.1093/nar/gkz707

By:

Lelyveld, Victor S;
O'Flaherty, Derek K;
Zhou, Lijun;
Izgu, Enver Cagri;
Szostak, Jack W

Publication type:

Article

Divergent prebiotic synthesis of pyrimidine and 8-oxo-purine ribonucleotides.

Published in:

Nature Communications, 2017, v. 8, n. 5, p. 15270, doi. 10.1038/ncomms15270

By:

Stairs, Shaun;
Nikmal, Arif;
Bučar, Dejan-Krešimir;
Zheng, Shao-Liang;
Szostak, Jack W.;
Powner, Matthew W.

Publication type:

Article

Collaboration between primitive cell membranes and soluble catalysts.

Published in:

Nature Communications, 2016, v. 7, n. 3, p. 11041, doi. 10.1038/ncomms11041

By:

Adamala, Katarzyna P.;
Engelhart, Aaron E.;
Szostak, Jack W.

Publication type:

Article

Comparative analysis of LIN28-RNA binding sites identified at single nucleotide resolution.

Published in:

RNA Biology, 2017, v. 14, n. 12, p. 1756, doi. 10.1080/15476286.2017.1356566

By:

Ransey, Elizabeth;
Björkbom, Anders;
Lelyveld, Victor S.;
Biecek, Przemyslaw;
Pantano, Lorena;
Szostak, Jack W.;
Sliz, Piotr

Publication type:

Article

Origins of life: Systems chemistry on early Earth.

Published in:

Nature, 2009, v. 459, n. 7244, p. 171, doi. 10.1038/459171a

By:

Szostak, Jack W.

Publication type:

Article