Works matching DE "HIGH throughput screening (Drug development)"

Results: 2950

LPS2336, a New TREK-1 Channel Activator Identified by High Throughput Screening.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 740, doi. 10.3390/biom15050740

By:

Boyer, Romane;
Bony, Romane;
Maugis, Maxence;
Schopp, Julien;
Leroux, Marion;
Michelin, Clément;
Gonthier, Laurie;
Grzeskiewicz, Quentin;
Jouannet, Alexandre;
Aissouni, Youssef;
Didier, Bruno;
Gulea, Mihaela;
Girard, Nicolas;
Cintrat, Jean-Christophe;
Dumeige, Antoine;
Busserolles, Jérôme;
Ducki, Sylvie;
Lolignier, Stéphane

Publication type:

Article

Letter: New Horizons in Biomarker Discovery: Assay Technologies for Personalized Drug Development.

Published in:

2025

By:

Singh, Dilpreet

Publication type:

Letter

Low-Cost Microfluidic Mixers: Are They up to the Task?

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 566, doi. 10.3390/pharmaceutics17050566

By:

Forrester, Jade;
Davidson, Callum G.;
Blair, May;
Donlon, Lynn;
McLoughlin, Daragh M.;
Obiora, Chukwuebuka R.;
Stockdale, Heather;
Thomas, Ben;
Nutman, Martina;
Brockbank, Sarah;
Rattray, Zahra;
Perrie, Yvonne

Publication type:

Article

Identification and Characterization of Antiviral Activity of Synthetic Compounds Against Mayaro Virus.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 5, p. 717, doi. 10.3390/ph18050717

By:

Andreolla, Ana Paula;
Koishi, Andrea Cristine;
Borges, Alessandra Abel;
Oliveira, Larissa Albuquerque de;
Oliveira, Viviane Guedes de;
Lima, Nerilson Marques;
Ávila, Eloah Pereira;
de Castro, Pedro Pôssa;
Amarante, Giovanni Wilson;
de Almeida, Mauro Vieira;
Bordignon, Juliano;
Duarte dos Santos, Claudia Nunes

Publication type:

Article

Identification of Bacterial Oligopeptidase B Inhibitors from Microbial Natural Products: Molecular Insights, Docking Studies, MD Simulations, and ADMET Predictions.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 5, p. 709, doi. 10.3390/ph18050709

By:

Mohamed, Malik Suliman;
Elsaman, Tilal;
Mohamed, Magdi Awadalla;
Eltayib, Eyman Mohamed;
Abdalla, Abualgasim Elgaili;
Idriss, Mona Timan

Publication type:

Article

Cell Ratio-Dependent Osteoblast–Endothelial Cell Crosstalk Promoting Osteogenesis–Angiogenesis Coupling via Regulation of Microfluidic Perfusion and Paracrine Signaling.

Published in:

Micromachines, 2025, v. 16, n. 5, p. 539, doi. 10.3390/mi16050539

By:

Wang, Yuexin;
Chen, Shu;
Fan, Wenwen;
Zhang, Sixian;
Chen, Xi

Publication type:

Article

A High-Throughput Cell-Based Luciferase Reporter Assay for Identifying Inhibitors of ASGR1.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4590, doi. 10.3390/ijms26104590

By:

Gan, Lingmin;
Zou, Haoyu;
Yang, Zhaoqi;
Wang, Juntao;
Sheng, Yunzhi;
Du, Pengfei;
Zhang, Shikun;
Feng, Zili

Publication type:

Article

Iranian Grape Waste: A High Potential Source for Screening of Bioethanol-Producing Microorganisms.

Published in:

Journal of Cell & Molecular Research, 2024, v. 16, n. 1, p. 1, doi. 10.22067/jcmr.2024.88136.1095

By:

Golestani, Robabeh;
Sang Atash, Masoumeh Mehraban;
Noshahri, Najme Gord;
Mehrjerdi, Mohammad Zare;
Yousefpoor, Yaser

Publication type:

Article

Immune-enrichment Predicts Response to Trastuzumab.

Published in:: Oncology (08909091), 2014, v. 28, n. 7, p. III
Publication type:: Article

基于网络药理学和分子对接技术探讨沙棘活性成分对非酒精性脂肪肝作用机制

Published in:

Chinese Nursing Research, 2023, v. 37, n. 16, p. 2853, doi. 10.12102/j.issn.1009-6493.2023.16.001

By:

高健;
吴胜男;
王晓静;
纪景馨;
张然;
程景民

Publication type:

Article

An Emerald in the Rough.

Published in:

Bio-IT World, 2010, v. 9, n. 1, p. 24

By:

DAVIES, KEVIN

Publication type:

Article

High Throughput Screening Retools for the Future.

Published in:

Bio-IT World, 2009, v. 8, n. 1, p. 20

By:

Glaser, Vicki

Publication type:

Article

PerkinElmer's Path to Biodiscovery.

Published in:: 2008
Publication type:: Interview

The Galileo Code.

Published in:

Bio-IT World, 2005, v. 4, n. 2, p. 24

By:

Davies, Kevin

Publication type:

Article

New Software for HTS.

Published in:

Bio-IT World, 2005, v. 4, n. 2, p. 16

By:

Uehling, Mark D.

Publication type:

Article

Tackling ADME/Tox Workflow.

Published in:

Bio-IT World, 2005, v. 4, n. 2, p. 18

By:

Salamone, Salvatore

Publication type:

Article

Channeling HPLC.

Published in:

Bio-IT World, 2004, v. 3, n. 8, p. 56

By:

Frederickson, Robert M.

Publication type:

Article

Is Microfluidics Equipped for HTS?

Published in:

Bio-IT World, 2004, v. 3, n. 5, p. 70

By:

Boguslavsky, Julia

Publication type:

Article

Finding the Perfect Fit.

Published in:

Bio-IT World, 2004, v. 3, n. 4, p. 36

By:

Branca, Malorye A.

Publication type:

Article

Beckman Coulter Displays Affinity for Multi-Mode HTS.

Published in:: 2003
Publication type:: Product Review

Chemical Control of Yeast Cell Division by Cross-Linked Shells of Catechol-Grafted Polyelectrolyte Multilayers.

Published in:

Macromolecular Rapid Communications, 2013, v. 34, n. 17, p. 1351, doi. 10.1002/marc.201300444

By:

Lee, Juno;
Yang, Sung Ho;
Hong, Seok‐Pyo;
Hong, Daewha;
Lee, Haeshin;
Lee, Hee‐Yoon;
Kim, Yang‐Gyun;
Choi, Insung S.

Publication type:

Article

Controlling the Crystallisation and Hydration State of Crystalline Porous Organic Salts.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 64, p. 1, doi. 10.1002/chem.202302420

By:

O'Shaughnessy, Megan;
Padgham, Alex C.;
Clowes, Rob;
Little, Marc A.;
Brand, Michael C.;
Qu, Hang;
Slater, Anna G.;
Cooper, Andrew I.

Publication type:

Article

Chiroptical Recognition of Carboxylates with Charge‐Neutral Double‐Stranded Zinc(II) Helicates.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 61, p. 1, doi. 10.1002/chem.202301613

By:

Kalarikkal, Malavika G.;
Drechsler, Christoph;
Tusha, Gers;
Schäfer, Lars V.;
Van Craen, David

Publication type:

Article

Combining Molecular Quantum Mechanical Modeling and Machine Learning for Accelerated Reaction Screening and Discovery.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 60, p. 1, doi. 10.1002/chem.202301957

By:

Casetti, Nicholas;
Alfonso‐Ramos, Javier E.;
Coley, Connor W.;
Stuyver, Thijs

Publication type:

Article

A Small‐Molecule Probe with a Dual Function of miRNA Inhibition and Target identification.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 3, p. 1, doi. 10.1002/chem.202202013

By:

Wang, Weishan;
Deng, Jiafang;
Zhang, Yan;
Li, Jinbo

Publication type:

Article

Cover Feature: High‐Throughput Platform for Novel Reaction Discovery (Chem. Eur. J. 50/2022).

Published in:

2022

By:

Lu, Xiao;
Luo, Zhiji;
Huang, Ruili;
Lo, Donald C.;
Huang, Wenwei

Publication type:

Abstract

High‐Throughput Platform for Novel Reaction Discovery.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 50, p. 1, doi. 10.1002/chem.202201421

By:

Lu, Xiao;
Luo, Zhiji;
Huang, Ruili;
Lo, Donald C.;
Huang, Wenwei

Publication type:

Article

Catechol Moiety Integrated Tri‐Aryl Type AIEgen for Visual and Quantitative Boronic Acid Detection.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 3, p. 1, doi. 10.1002/chem.202103351

By:

Hu, Renjian;
Lin, Shiyun;
Wang, Mengshi;
Li, Ruoxin;
Shuai, Zhigang;
Wei, Yen

Publication type:

Article

Identifizierung und Strukturbestimmung eines niedermolekularen Aktivators der LFA-1/ICAM-1-Bindung.

Published in:

Angewandte Chemie, 2014, v. 126, n. 17, p. 4410, doi. 10.1002/ange.201310240

By:

Hintersteiner, Martin;
Kallen, Jörg;
Schmied, Mario;
Graf, Christine;
Jung, Thomas;
Mudd, Gemma;
Shave, Steven;
Gstach, Hubert;
Auer, Manfred

Publication type:

Article

Rücktitelbild: Engineering of P450pyr Hydroxylase for the Highly Regio- and Enantioselective Subterminal Hydroxylation of Alkanes (Angew. Chem. 12/2014).

Published in:

Angewandte Chemie, 2014, v. 126, n. 12, p. 3348, doi. 10.1002/ange.201401084

By:

Yang, Yi;
Liu, Ji;
Li, Zhi

Publication type:

Article

Engineering of P450pyr Hydroxylase for the Highly Regio- and Enantioselective Subterminal Hydroxylation of Alkanes.

Published in:

Angewandte Chemie, 2014, v. 126, n. 12, p. 3184, doi. 10.1002/ange.201311091

By:

Yang, Yi;
Liu, Ji;
Li, Zhi

Publication type:

Article

Synthesis of Complex and Diverse Compounds through Ring Distortion of Abietic Acid.

Published in:

Angewandte Chemie, 2014, v. 126, n. 1, p. 224, doi. 10.1002/ange.201308743

By:

Rafferty, Ryan J.;
Hicklin, Robert W.;
Maloof, Katherine A.;
Hergenrother, Paul J.

Publication type:

Article

Selection criteria for drug-like compounds.

Published in:

Medicinal Research Reviews, 2003, v. 23, n. 3, p. 302, doi. 10.1002/med.10041

By:

Ingo Muegge

Publication type:

Article

Assessment of Bacterial Community Composition of Anaerobic Granular Sludge in Response to Short-Term Uranium Exposure.

Published in:

Microbial Ecology, 2018, v. 76, n. 3, p. 648, doi. 10.1007/s00248-018-1152-x

By:

Zeng, Taotao;
Zhang, Shiqi;
Gao, Xiang;
Wang, Guohua;
Lens, Piet N. L.;
Xie, Shuibo

Publication type:

Article

Development of a novel filter insert to enable high throughput testing of thermodynamic solubility.

Published in:

Chemical Engineering Research & Design: Transactions of the Institution of Chemical Engineers Part A, 2023, v. 200, p. 77, doi. 10.1016/j.cherd.2023.09.044

By:

Lopez, Mike

Publication type:

Article

Emerging microfluidic platforms for crystallization process development.

Published in:

Chemical Engineering Research & Design: Transactions of the Institution of Chemical Engineers Part A, 2023, v. 197, p. 908, doi. 10.1016/j.cherd.2023.08.021

By:

Chauhan, Rohit;
Minocha, Nitin;
Coliaie, Paria;
Singh, Priyanka G.;
Korde, Akshay;
Kelkar, Manish S.;
Langston, Marianne;
Liu, Chengxiang;
Nazemifard, Neda;
Patience, Daniel;
Skliar, Dimitri;
Nere, Nandkishor K.;
Singh, Meenesh R.

Publication type:

Article

Exploring the hydrogenation of furfural in the liquid phase by high-throughput screening of commercial catalysts: Effects of temperature, solvents, and promoters on the production of 2-methylfuran.

Published in:

Chemical Engineering Research & Design: Transactions of the Institution of Chemical Engineers Part A, 2023, v. 197, p. 968, doi. 10.1016/j.cherd.2023.08.010

By:

Giorgianni, Gianfranco;
Perathoner, Siglinda;
Centi, Gabriele;
Soo-Tang, Siu-Ha;
de Jong, Ed;
van der Waal, Jan C.;
Abate, Salvatore

Publication type:

Article

Use of an online surveillance system for screening drug interactions in prescriptions in community pharmacies.

Published in:

European Journal of Clinical Pharmacology, 2006, v. 62, n. 8, p. 661, doi. 10.1007/s00228-006-0149-4

By:

Heikkilä, Tiina;
Lekander, Tuula;
Raunio, Hannu

Publication type:

Article

Estimating the starting dose for entry into humans: principles and practice.

Published in:

European Journal of Clinical Pharmacology, 2002, v. 57, n. 12, p. 835, doi. 10.1007/s00228-001-0405-6

By:

Reigner, Bruno G.;
Blesch, Karen Smith

Publication type:

Article

A high-throughput screening strategy for nitrile-hydrolyzing enzymes based on ferric hydroxamate spectrophotometry.

Published in:

Applied Microbiology & Biotechnology, 2011, v. 89, n. 3, p. 817, doi. 10.1007/s00253-010-2977-5

By:

Yu-Cai He;
Cui-Luan Ma;
Jian-He Xu;
Li Zhou

Publication type:

Article

α- and β-tubulin from Phytophthora capsici KACC 40483: molecular cloning, biochemical characterization, and antimicrotubule screening.

Published in:

Applied Microbiology & Biotechnology, 2009, v. 82, n. 3, p. 513, doi. 10.1007/s00253-008-1821-7

By:

Koo, Bon-Sung;
Park, Haechul;
Kalme, Satish;
Park, Hye-Yeon;
Han, Jin;
Yeo, Yun-Soo;
Yoon, Sang-Hong;
Kim, Soo-Jin;
Lee, Chang-Muk;
Yoon, Moon-Young

Publication type:

Article

Semi-rational design of L-amino acid deaminase for production of pyruvate and d-alanine by Escherichia coli whole-cell biocatalyst.

Published in:

Amino Acids, 2021, v. 53, n. 9, p. 1361, doi. 10.1007/s00726-021-03067-8

By:

Liu, Ke;
Yu, Haoran;
Sun, Guoyun;
Liu, Yanfeng;
Li, Jianghua;
Du, Guocheng;
Lv, Xueqin;
Liu, Long

Publication type:

Article

Phage display biopanning and isolation of target-unrelated peptides: in search of nonspecific binders hidden in a combinatorial library.

Published in:

Amino Acids, 2016, v. 48, n. 12, p. 2699, doi. 10.1007/s00726-016-2329-6

By:

Bakhshinejad, Babak;
Zade, Hesam;
Shekarabi, Hosna;
Neman, Sara

Publication type:

Article

Increased thermostability of microbial transglutaminase by combination of several hot spots evolved by random and saturation mutagenesis.

Published in:

Amino Acids, 2012, v. 42, n. 2/3, p. 987, doi. 10.1007/s00726-011-1015-y

By:

Buettner, Karin;
Hertel, Thomas;
Pietzsch, Markus

Publication type:

Article

Assessment of deoxyhypusine hydroxylase as a putative, novel drug target.

Published in:

Amino Acids, 2010, v. 38, n. 2, p. 471, doi. 10.1007/s00726-009-0406-9

By:

Kerscher, B.;
Nzukou, E.;
Kaiser, A.

Publication type:

Article

Measuring residual transpiration in plants: a comparative analysis of different methods.

Published in:

Functional Plant Biology, 2023, v. 50, n. 12, p. 983, doi. 10.1071/FP23157

By:

Hasanuzzaman, Md.;
Chakraborty, Koushik;
Zhou, Meixue;
Shabala, Sergey

Publication type:

Article

A high-throughput method for measuring critical thermal limits of leaves by chlorophyll imaging fluorescence.

Published in:

Functional Plant Biology, 2021, v. 48, n. 6, p. 634, doi. 10.1071/FP20344

By:

Arnold, Pieter A.;
Briceño, Verónica F.;
Gowland, Kelli M.;
Catling, Alexandra A.;
Bravo, León A.;
Nicotra, Adrienne B.

Publication type:

Article

Impact of elevated CO<sub>2</sub> and heat stress on wheat pollen viability and grain production.

Published in:

Functional Plant Biology, 2021, v. 48, n. 5, p. 503, doi. 10.1071/FP20187

By:

Bokshi, Anowarul I.;
Tan, Daniel K. Y.;
Thistlethwaite, Rebecca J.;
Trethowan, Richard;
Kunz, Karolin

Publication type:

Article

Identification of inhibitors of human ChaC1, a cytoplasmic glutathione degrading enzyme through high throughput screens in yeast.

Published in:

Biochemical Journal, 2024, v. 481, n. 20, p. 1475, doi. 10.1042/BCJ20240447

By:

Suyal, Shradha;
Choudhury, Chinmayee;
Kaur, Deepinder;
Bachhawat, Anand K.

Publication type:

Article

A curated list of targeted optimized promiscuous ketoreductases (TOP-K).

Published in:

Biochemical Journal, 2023, v. 480, n. 13, p. 975, doi. 10.1042/BCJ20230051

By:

Shanbhag, Anirudh P.;
Rajagopal, Sreenath;
Ghatak, Arindam;
Katagihallimath, Nainesh;
Subramanian, Ramaswamy;
Datta, Santanu

Publication type:

Article