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- Title
Frontispiece: Reductive Aldol‐type Reactions in the Synthesis of Pharmaceuticals.
- Authors
Runikhina, Sofiya; Eremin, Dmitry; Chusov, Denis
- Abstract
Keywords: aldol; C-C bond formation; condensation; hydrogenation; reductive alkylation EN aldol C-C bond formation condensation hydrogenation reductive alkylation 1 1 1 11/09/21 20211105 NES 211105 The aldol-type reaction became one of the forefathers of C-C bond formation reactions. Aldol, C-C bond formation, condensation, hydrogenation, reductive alkylation This Review focuses on reductive aldol-type alkylation methods implemented to the synthesis of ten approved drug substances.
- Subjects
DRUGS; ALDOLS; ALKYLATION; ASYMMETRIC synthesis; HYDROGENATION; CONDENSATION
- Publication
Chemistry - A European Journal, 2021, Vol 27, Issue 62, p1
- ISSN
0947-6539
- Publication type
Academic Journal
- DOI
10.1002/chem.202101768