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Title: Cover Feature: Rapid and Mild Lactamization Using Highly Electrophilic Triphosgene in a Microflow Reactor (Chem. Eur. J. 27/2021).
Authors: Fuse, Shinichiro; Komuro, Keiji; Otake, Yuma; Masui, Hisashi; Nakamura, Hiroyuki
Abstract: Amides, lactams, microreactors, peptides, synthetic methods Various lactams as well as a cyclic peptide containing acid- and/or heat-labile functional groups were synthesized in good to high yields without tedious purifications. Keywords: amides; lactams; microreactors; peptides; synthetic methods EN amides lactams microreactors peptides synthetic methods 7468 7468 1 05/17/21 20210512 NES 210512 B Rapid (0.5 to 10 s), mild, inexpensive, and less wasteful lactamization b was achieved using highly electrophilic triphosgene in a micro-flow reactor.
Subjects: PEPTIDOMIMETICS; LACTAMS
Publication: Chemistry - A European Journal, 2021, Vol 27, Issue 27, p7468
ISSN: 0947-6539
Publication type: Academic Journal
DOI: 10.1002/chem.202101330

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Cover Feature: Rapid and Mild Lactamization Using Highly Electrophilic Triphosgene in a Microflow Reactor (Chem. Eur. J. 27/2021).