Results
Title

Intermolecular Hydroaminoalkylation of Alkynes.

Authors

Kaper, Tobias; Fischer, Malte; Thye, Hermann; Geik, Dennis; Schmidtmann, Marc; Beckhaus, Ruediger; Doye, Sven

Abstract

Intermolecular hydroaminoalkylation reactions of alkynes with secondary amines, which selectively give access to allylic amines with E configuration of the alkene unit, are achieved in the presence of titanium catalysts. Successful reactions of symmetrically substituted diaryland dialkylalkynes as well as a terminal alkyne take place with N-benzylanilines, N-alkylanilines, and N-alkylbenzylamines.

Subjects

ALKYNES; TITANIUM catalysts; SECONDARY amines; AMINES

Publication

Chemistry - A European Journal, 2021, Vol 27, Issue 23, p6899

ISSN

0947-6539

Publication type

Academic Journal

DOI

10.1002/chem.202100238