Title: Redox‐Neutral Tetrafluoroethylation of Aryl Alkynes with 1,1,2,2‐Tetrafluoroethane Sulfonic Acid Leading to α‐Tetrafluoroethylated Acetophenones.
Authors: Kawamoto, Takuji; Noguchi, Kohki; Takata, Ryotaro; Sasaki, Rio; Matsubara, Hiroshi; Kamimura, Akio
Abstract: The redox‐neutral tetrafluoroethylation of alkynes with 1,1,2,2‐tetrafluroroethanesulfonic acid (TFESA) and azobis(isobutyronitrile) (AIBN) proceeds via the formation of vinyl tetrafluoroethanesulfonates followed by a radical tetrafluoroethylation. Experimental and theoretical results support an intermolecular reaction.
Subjects: ACETOPHENONE; ALKYNES
Publication: Chemistry - A European Journal, 2021, Vol 27, Issue 37, p9529
ISSN: 0947-6539
Publication type: Academic Journal
DOI: 10.1002/chem.202100137

Redox‐Neutral Tetrafluoroethylation of Aryl Alkynes with 1,1,2,2‐Tetrafluoroethane Sulfonic Acid Leading to α‐Tetrafluoroethylated Acetophenones.

Kawamoto, Takuji; Noguchi, Kohki; Takata, Ryotaro; Sasaki, Rio; Matsubara, Hiroshi; Kamimura, Akio