Title: Cover Feature: Controlling Regioselectivity in Palladium‐Catalyzed C−H Activation/Aryl–Aryl Coupling of 4‐Phenylamino[2.2]paracyclophane (Chem. Eur. J. 61/2020).
Authors: Zippel, Christoph; Spuling, Eduard; Hassan, Zahid; Polamo, Mika; Nieger, Martin; Bräse, Stefan
Abstract: Keywords: [2.2]paracyclophane; aryl-aryl coupling; Buchwald-Hartwig amination; C-H activation; cyclophanes; palladium EN [2.2]paracyclophane aryl-aryl coupling Buchwald-Hartwig amination C-H activation cyclophanes palladium 13746 13746 1 11/06/20 20201102 NES 201102 B C-H activation is targeted b in the cover image. This work reports the palladium-catalyzed preferential and exclusively I para i - site-selective C-H activation/aryl-aryl bond formation with a preference over I N i -arylation under Buchwald-Hartwig amination reaction conditions of 4- I N i -phenylamino[2.2]paracyclophane. [2.2]paracyclophane, aryl-aryl coupling, Buchwald-Hartwig amination, C-H activation, cyclophanes, palladium.
Subjects: CYCLOPHANES; AMINATION
Publication: Chemistry - A European Journal, 2020, Vol 26, Issue 61, p13746
ISSN: 0947-6539
Publication type: Academic Journal
DOI: 10.1002/chem.202004087

Cover Feature: Controlling Regioselectivity in Palladium‐Catalyzed C−H Activation/Aryl–Aryl Coupling of 4‐Phenylamino[2.2]paracyclophane (Chem. Eur. J. 61/2020).

Zippel, Christoph; Spuling, Eduard; Hassan, Zahid; Polamo, Mika; Nieger, Martin; Bräse, Stefan