Results
Title

UV‐Induced 1,3,4‐Oxadiazole Formation from 5‐Substituted Tetrazoles and Carboxylic Acids in Flow.

Authors

Green, Luke; Livingstone, Keith; Bertrand, Sophie; Peace, Simon; Jamieson, Craig

Abstract

A range of 1,3,4‐oxadiazoles have been synthesized using a UV‐B activated flow approach starting from carboxylic acids and 5‐substituted tetrazoles. The application of UV light represents an attractive alternative to the traditional thermolytic approach and has demonstrated comparable efficiency and versatility, with a diverse substrate scope, including the incorporation of highly substituted amino acids.

Subjects

CARBOXYLIC acids; NITRILIMINES; THIADIAZOLES; TETRAZOLES; AMINO acids

Publication

Chemistry - A European Journal, 2020, Vol 26, Issue 65, p14866

ISSN

0947-6539

Publication type

Academic Journal

DOI

10.1002/chem.202002896