Works matching DE "TRANSGENIC mice"

Results: 5000

Early onset and enhanced growth of autochthonous mammary carcinomas in C3-deficient Her2/neu transgenic mice.

Published in:

OncoImmunology, 2013, v. 2, n. 9, p. e26137-1, doi. 10.4161/onci.26137

By:

Bandini, Silvio;
Curcio, Claudia;
Macagno, Marco;
Quaglino, Elena;
Arigoni, Maddalena;
Lanzardo, Stefania;
Hysi, Albana;
Barutello, Giuseppina;
Consolino, Lorena;
Longo, Dario Livio;
Musiani, Piero;
Forni, Guido;
Iezzi, Manuela;
Cavallo, Federica

Publication type:

Article

miR-101a-3p Impairs Synaptic Plasticity and Contributes to Synucleinopathy.

Published in:

Journal of Parkinson's Disease, 2023, v. 13, n. 2, p. 179, doi. 10.3233/JPD-225055

By:

Xylaki, Mary;
Paiva, Isabel;
Al-Azzani, Mohammed;
Gerhardt, Ellen;
Jain, Gaurav;
Islam, Md Rezaul;
Vasili, Eftychia;
Wassouf, Zinah;
Schulze-Hentrich, Julia M.;
Fischer, André;
Outeiro, Tiago Fleming

Publication type:

Article

Effects of Gut Microbiota Alterations on Motor, Gastrointestinal, and Behavioral Phenotype in a Mouse Model of Parkinson's Disease.

Published in:

Journal of Parkinson's Disease, 2022, v. 12, n. 5, p. 1479, doi. 10.3233/JPD-223165

By:

Radisavljevic, Nina;
Cirstea, Mihai;
Bauer, Kylynda;
Lo, Christine;
Metcalfe-Roach, Avril;
Bozorgmehr, Tahereh;
Bar-Yoseph, Haggai;
Brett Finlay, B.

Publication type:

Article

Quantitative Profiling of Synuclein Species: Application to Transgenic Mouse Models of Parkinson's Disease.

Published in:

Journal of Parkinson's Disease, 2020, v. 10, n. 2, p. 613, doi. 10.3233/JPD-191835

By:

Singh, Serena;
Khayachi, Anouar;
Milnerwood, Austen J.;
DeMarco, Mari L.

Publication type:

Article

Behavioral Deficits and Striatal DA Signaling in LRRK2 p.G2019S Transgenic Rats: A Multimodal Investigation Including PET Neuroimaging.

Published in:

Journal of Parkinson's Disease, 2014, v. 4, n. 3, p. 483, doi. 10.3233/JPD-140344

By:

Walker, Matthew D.;
Volta, Mattia;
Cataldi, Stefano;
Dinelle, Katherine;
Beccano-Kelly, Dayne;
Munsie, Lise;
Kornelsen, Rick;
Mah, Chenoa;
Chou, Patrick;
Co, Kimberley;
Khinda, Jaskaran;
Mroczek, Marta;
Bergeron, Sabrina;
Yu, Katrina;
Cao, Li Ping;
Funk, Natalja;
Ott, Thomas;
Galter, Dagmar;
Riess, Olaf;
Biskup, Saskia

Publication type:

Article

Dietary olive oil induces cannabinoid CB2 receptor expression in adipose tissue of ApcMin/+ transgenic mice.

Published in:

Nutrition & Healthy Aging, 2016, v. 4, n. 1, p. 73, doi. 10.3233/NHA-160008

By:

Notarnicola, Maria;
Tutino, Valeria;
Tafaro, Angela;
Bianco, Giusy;
Guglielmi, Emilia;
Caruso, Maria Gabriella

Publication type:

Article

Effects of vincristine on the properties of low threshold mechanoreceptors and high threshold mechanoreceptors in the hindpaw glabrous skin of mice.

Published in:

Molecular Brain, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13041-025-01223-9

By:

Yamada, Akihiro;
Yamada, Ayaka I.;
Ling, Jennifer;
Gu, Jianguo G.

Publication type:

Article

Epac1 increases myosin regulatory light-chain phosphorylation, energetic cost of contraction, and susceptibility to heart failure.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0325986

By:

Ohnuki, Yoshiki;
Suita, Kenji;
Ishikawa, Misao;
Mototani, Yasumasa;
Nariyama, Megumi;
Ito, Aiko;
Matsuo, Ichiro;
Hayakawa, Yoshio;
Morii, Akinaka;
Mitsubayashi, Takao;
Saeki, Yasutake;
Ishikawa, Yoshihiro;
Okumura, Satoshi

Publication type:

Article

Establishment of a mouse lung cancer organoid model and its applications for therapeutic screening.

Published in:

Biological Procedures Online, 2025, v. 27, n. 1, p. 1, doi. 10.1186/s12575-025-00284-3

By:

Liu, Yajing;
Ning, Jingyuan;
Wang, Donglai

Publication type:

Article

Severe enterovirus A71 pathogenesis and immune responses in human nucleolin transgenic mice.

Published in:

Medical Microbiology & Immunology, 2025, v. 214, n. 1, p. 1, doi. 10.1007/s00430-025-00842-2

By:

Hsiao, Nien-En;
Wang, Ya-Fang;
Lin, Yi-Chen;
Chou, Wei-Ting;
Hsu, Li-Jin;
Wang, Shih-Min;
Wang, Jen-Ren;
Lai, Ming-Derg;
Chen, Shun-Hua;
Chang, Chuan-Fa

Publication type:

Article

Characterization of prion strains and peripheral prion infectivity patterns in E200K genetic CJD patients.

Published in:

Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-025-02903-5

By:

Barrio, Tomás;
Douet, Jean-Yves;
Žáková, Dana;
Eraña, Hasier;
Huor, Alvina;
Cassard, Hervé;
Alzuguren, Oihane;
Lugan, Séverine;
Aron, Naïma;
Péran, Patrice;
Castilla, Joaquín;
Andréoletti, Olivier

Publication type:

Article

RANKL Drives Bone Metastasis in Mammary Cancer: Protective Effects of Anti-Resorptive Treatments.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 4990, doi. 10.3390/ijms26114990

By:

Gkikopoulou, Evi;
Syrigos, Christos-Chrysovalantis;
Mantogiannakou, Ioanna;
Petraki, Chrysa-Eleni;
Stathopoulou, Melina;
Dragolia, Melina;
Rinotas, Vagelis;
Ntafis, Vasileios;
Rauner, Martina;
Douni, Eleni

Publication type:

Article

Mouse SPAG6L, a Key Cytoskeleton Modulator Essential for Male Germ Cell Development, Is Not Required for Sertoli Cell Function.

Published in:

Cells (2073-4409), 2025, v. 14, n. 11, p. 783, doi. 10.3390/cells14110783

By:

Li, Tao;
Li, Wei;
Zheng, Cheng;
Dufour, Jannette M.;
Walker, William H.;
Yuan, Shuiqiao;
Zhang, Zhibing

Publication type:

Article

Generation and characterization of BAC transgenic mouse lines expressing a fluorescent protein in trigeminal and dorsal root ganglion neurons.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0321014

By:

Banerjee, Piu;
Sato, Takuya;
Iwasato, Takuji

Publication type:

Article

Reduction in myofilament Ca2+ sensitivity partially ameliorates the cardiac phenotype in hypertrophic cardiomyopathy linked to a TnT-R92Q mutation.

Published in:

Frontiers in Physiology, 2025, p. 1, doi. 10.3389/fphys.2025.1600117

By:

Langa, Paulina;
Bacon, Angelie;
Warren, Chad M.;
Chowdhury, Shamim A. K.;
Halas, Monika;
Fernandes, Aurelia A.;
McCauley, Mark D.;
Goldspink, Paul H.;
Solaro, R. John;
Wolska, Beata M.

Publication type:

Article

Bidirectional modulation of Alzheimer's disease via gut microbiota: rescue by fecal transplantation from healthy donors and aggravation by colitis-associated dysbiosis.

Published in:

Frontiers in Neuroscience, 2025, p. 1, doi. 10.3389/fnins.2025.1593854

By:

Zhou, Chenglong;
Feng, Xin;
Liu, Huina;
Cai, Ting;
Li, Yihong;
Fan, Huadong

Publication type:

Article

Autophagy across tissues of aging mice.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0325505

By:

Carosi, Julian M.;
Martin, Alexis;
Hein, Leanne K.;
Hassiotis, Sofia;
Hattersley, Kathryn J.;
Turner, Bradley J.;
Fourrier, Célia;
Bensalem, Julien;
Sargeant, Timothy J.

Publication type:

Article

Anti-pyroglutamate-3 Aβ immunotherapy engages microglia and inhibits amyloid accumulation in transgenic mouse models of Aβ amyloidosis.

Published in:

Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-025-02892-5

By:

Liao, Fan;
Calvo-Rodriguez, Maria;
Chhaya, Meha;
Sefrin, Julian P;
Charych, Erik I;
Mezler, Mario;
Clausznitzer, Diana;
McGlame, Emily J;
Zhao, Karen;
Rodgers, Allison;
Cao, Yang;
Secker, Philipp F;
Fernandez Garcia-Agudo, Laura;
Huang, Lili;
Klein, Corinna;
Dellovade, Tammy;
Karran, Eric

Publication type:

Article

Trans amplifying mRNA vaccine expressing consensus spike elicits broad neutralization of SARS CoV 2 variants.

Published in:

NPJ Vaccines, 2025, v. 10, n. 1, p. 1, doi. 10.1038/s41541-025-01166-1

By:

Gontu, Abhinay;
Misra, Sougat;
Chothe, Shubhada K.;
Ramasamy, Santhamani;
Jakka, Padmaja;
Byukusenge, Maurice;
LaBella, Lindsey C.;
Nair, Meera Surendran;
Jayarao, Bhushan M.;
Archetti, Marco;
Nissly, Ruth H.;
Kuchipudi, Suresh V.

Publication type:

Article

Structural and Functional Analysis of the Human IQSEC2 S1474Qfs*133 Mutation.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 635, doi. 10.3390/biom15050635

By:

Israel, Yonat;
Lowenkamp, Aaron;
Shokhen, Michael;
Netser, Shai;
Wagner, Shlomo;
Zarowin, Joseph;
Orth, Shaun;
Borisov, Veronika;
Lache, Orit;
Levy, Nina S.;
Levy, Andrew P.

Publication type:

Article

Increased Circulating Extracellular Superoxide Dismutase Attenuates Platelet–Neutrophil Interactions.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2025, v. 72, n. 6, p. 653, doi. 10.1165/rcmb.2024-0292OC

By:

Sul, Christina;
Lewis, Caitlin V.;
Posey, Janelle;
Jordan, Mariah;
Colon Hidalgo, Daniel;
Porfilio, Timothy;
Elajaili, Hanan;
McCormack, Genevieve;
Burciaga, Samuel;
Delaney, Cassidy;
Nozik, Eva S.

Publication type:

Article

Ovalbumin-specific regulatory T cells differentiated from the naïve phenotype (CD44loCD62Lhi) in mesenteric lymph nodes stably suppress enteropathy even in severe food-allergic mice.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0324105

By:

Shibahara, Kyoko;
Hoshino, Tomohiro;
Nakanishi, Haruka;
Nishitsuji, Kosuke;
Soga, Kohei;
Bamba, Yoshiyo;
Hachimura, Satoshi;
Nakajima-Adachi, Haruyo

Publication type:

Article

Transgene Mapping in Animals: What to Choose?

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4705, doi. 10.3390/ijms26104705

By:

Smirnov, Alexander;
Makarenko, Maksim;
Yunusova, Anastasia

Publication type:

Article

Tissue- and age-specific DNA replication patterns at the CTG/CAG-expanded human myotonic dystrophy type 1 locus.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 9, p. 1079, doi. 10.1038/nsmb.1876

By:

Cleary, John D;
Tomé, Stéphanie;
López Castel, Arturo;
Panigrahi, Gagan B;
Foiry, Laurent;
Hagerman, Katharine A;
Sroka, Hana;
Chitayat, David;
Gourdon, Geneviève;
Pearson, Christopher E

Publication type:

Article

Viral pathogenesis: Turning virus spread on its head.

Published in:

Nature Reviews Microbiology, 2008, v. 6, n. 6, p. 413, doi. 10.1038/nrmicro1914

By:

Jones, Susan

Publication type:

Article

HMGB1 Mediates Endogenous TLR2 Activation and Brain Tumor Regression.

Published in:

PLoS Medicine, 2009, v. 6, n. 1, p. e1000010, doi. 10.1371/journal.pmed.1000010

By:

Curtin, James F;
Liu, Naiyou;
Candolfi, Marianela;
Xiong, Weidong;
Assi, Hikmat;
Yagiz, Kader;
Edwards, Matthew R;
Michelsen, Kathrin S;
Kroeger, Kurt M;
Liu, Chunyan;
Muhammad, A. K. M. Ghulam;
Clark, Mary C;
Arditi, Moshe;
Comin-Anduix, Begonya;
Ribas, Antoni;
Lowenstein, Pedro R;
Castro, Maria G

Publication type:

Article

Persistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer disease.

Published in:

2005

By:

Jankowsky, Joanna L.;
Slunt, Hilda H.;
Gonzales, Victoria;
Savonenko, Alena V.;
Wen, Jason C.;
Jenkins, Nancy A.;
Copeland, Neal G.;
Younkin, Linda H.;
Lester, Henry A.;
Younkin, Steven G.;
Borchelt, David R.

Publication type:

journal article

Breaking up (amyloid) is hard to do.

Published in:

2005

By:

Gandy, Sam;
Heppner, Frank L.

Publication type:

journal article

β-Galactosidase detection as an indicator of endogenous PTHrP in cartilage.

Published in:

Biotechnic & Histochemistry, 2008, v. 83, n. 2, p. 89, doi. 10.1080/10520290802127834

By:

Chen, X-S;
Troiano, Nw;
Kacena, Ma

Publication type:

Article

Cationic Carbosilane Dendritic Systems as Promising Anti‐Amyloid Agents in Type 2 Diabetes.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 34, p. 7609, doi. 10.1002/chem.202000091

By:

Lozano‐Cruz, Tania;
Alcarraz‐Vizán, Gema;
Mata, F. Javier;
Pablo, Sara;
Ortega, Paula;
Duarte, Yorley;
Bravo‐Moraga, Felipe;
González‐Nilo, Fernando D.;
Novials, Anna;
Gómez, Rafael

Publication type:

Article

Mammalian sex determination-insights from humans and mice.

Published in:

Chromosome Research, 2012, v. 20, n. 1, p. 215, doi. 10.1007/s10577-012-9274-3

By:

Eggers, Stefanie;
Sinclair, Andrew

Publication type:

Article

Imaging of changes in copper trafficking and redistribution in a mouse model of Niemann-Pick C disease using positron emission tomography.

Published in:

BioMetals, 2019, v. 32, n. 2, p. 293, doi. 10.1007/s10534-019-00185-5

By:

Baguña Torres, Julia;
Yu, Zilin;
Bordoloi, Jayanta;
Sunassee, Kavitha;
Smith, David;
Smith, Claire;
Chen, Oscar;
Purchase, Rupert;
Tuschl, Karin;
Spencer, John;
Platt, Frances;
Blower, Philip J.

Publication type:

Article

Diffusion MRI in 2‐Month‐Old Mouse Brain Predicts Alzheimer's Pathology Genotype.

Published in:

NMR in Biomedicine, 2025, v. 38, n. 4, p. 1, doi. 10.1002/nbm.70018

By:

Falangola, Maria Fatima;
Granger, Bryan;
Voltin, Joshua;
Nietert, Paul J.;
Berto, Stefano;
Jensen, Jens H.

Publication type:

Article

Further refining the boundaries of the hippocampus CA2 with gene expression and connectivity: Potential subregions and heterogeneous cell types.

Published in:

Hippocampus, 2023, v. 33, n. 3, p. 150, doi. 10.1002/hipo.23508

By:

Bienkowski, Michael S.

Publication type:

Article

Chronic stress has different immediate and delayed effects on hippocampal calretinin‐ and somatostatin‐positive cells.

Published in:

Hippocampus, 2021, v. 31, n. 2, p. 221, doi. 10.1002/hipo.23285

By:

Ortiz, J. Bryce;
Newbern, Jason;
Conrad, Cheryl D.

Publication type:

Article

Spatial reference memory in GluR-A-deficient mice using a novel hippocampal-dependent paddling pool escape task.

Published in:

Hippocampus, 2004, v. 14, n. 2, p. 216, doi. 10.1002/hipo.10168

By:

W.B. Schmitt;
R.M.J. Deacon;
D. Reisel;
R. Sprengel;
P.H. Seeburg;
J.N.P. Rawlins;
D.M. Bannerman

Publication type:

Article

Morphological and electrophysiological properties of serotonin neurons with NMDA modulation in the mesencephalic locomotor region of neonatal ePet-EYFP mice.

Published in:

Experimental Brain Research, 2019, v. 237, n. 12, p. 3333, doi. 10.1007/s00221-019-05675-z

By:

Ge, Renkai;
Chen, Ke;
Cheng, Yi;
Dai, Yue

Publication type:

Article

Differential regulation of axon outgrowth and reinnervation by neurotrophin-3 and neurotrophin-4 in the hippocampal formation.

Published in:

Experimental Brain Research, 2010, v. 205, n. 2, p. 215, doi. 10.1007/s00221-010-2355-7

By:

Hechler, Daniel;
Boato, Francesco;
Nitsch, Robert;
Hendrix, Sven

Publication type:

Article

Retrogradely transported siRNA silences human mutant SOD1 in spinal cord motor neurons.

Published in:

Experimental Brain Research, 2009, v. 195, n. 1, p. 1, doi. 10.1007/s00221-009-1742-4

By:

Rizvanov, Albert;
Mukhamedyarov, Marat;
Palotás, András;
Islamov, Rustem

Publication type:

Article

β3-Adrenergic receptor overexpression in cardiomyocytes preconditions mitochondria to withstand ischemia–reperfusion injury.

Published in:

Basic Research in Cardiology, 2024, v. 119, n. 5, p. 773, doi. 10.1007/s00395-024-01072-y

By:

Fernández-Tocino, Miguel;
Pun-Garcia, Andrés;
Gómez, Mónica;
Clemente-Moragón, Agustín;
Oliver, Eduardo;
Villena-Gutierrez, Rocío;
Trigo-Anca, Sofía;
Díaz-Guerra, Anabel;
Sanz-Rosa, David;
Prados, Belén;
del Campo, Lara;
Andrés, Vicente;
Fuster, Valentín;
de la Pompa, José Luis;
Cádiz, Laura;
Ibañez, Borja

Publication type:

Article

Inducible cardiac-specific overexpression of cyclooxygenase-2 (COX-2) confers resistance to ischemia/reperfusion injury.

Published in:

Basic Research in Cardiology, 2019, v. 114, n. 5, p. N.PAG, doi. 10.1007/s00395-019-0741-2

By:

Guo, Yiru;
Nong, Yibing;
Tukaye, Deepali Nivas;
Rokosh, Gregg;
Du, Junjie;
Zhu, Xiaoping;
Book, Michael;
Tomlin, Alex;
Li, Qianhong;
Bolli, Roberto

Publication type:

Article

Increased calpain-1 in mitochondria induces dilated heart failure in mice: role of mitochondrial superoxide anion.

Published in:

Basic Research in Cardiology, 2019, v. 114, n. 3, p. N.PAG, doi. 10.1007/s00395-019-0726-1

By:

Cao, Ting;
Fan, Shuai;
Zheng, Dong;
Wang, Grace;
Yu, Yong;
Chen, Ruizhen;
Song, Long-Sheng;
Fan, Guo-Chang;
Zhang, Zhuxu;
Peng, Tianqing

Publication type:

Article

Vinexin-β protects against cardiac hypertrophy by blocking the Akt-dependent signalling pathway.

Published in:

Basic Research in Cardiology, 2013, v. 108, n. 2, p. 1, doi. 10.1007/s00395-013-0338-0

By:

Chen, Ke;
Gao, Lu;
Liu, Yu;
Zhang, Yan;
Jiang, Ding-Sheng;
Wei, Xiang;
Zhu, Xue;
Zhang, Rui;
Chen, Yingjie;
Yang, Qinglin;
Kioka, Noriyuki;
Zhang, Xiao-Dong;
Li, Hongliang

Publication type:

Article

Role of endothelial Nox2 NADPH oxidase in angiotensin II-induced hypertension and vasomotor dysfunction.

Published in:

Basic Research in Cardiology, 2011, v. 106, n. 4, p. 527, doi. 10.1007/s00395-011-0179-7

By:

Murdoch, Colin;
Alom-Ruiz, Sara;
Wang, Minshu;
Zhang, Min;
Walker, Simon;
Yu, Bin;
Brewer, Alison;
Shah, Ajay

Publication type:

Article

Dissection of the voltage-activated potassium outward currents in adult mouse ventricular myocytes: I, I, I, I, and I.

Published in:

Basic Research in Cardiology, 2011, v. 106, n. 2, p. 189, doi. 10.1007/s00395-010-0134-z

By:

Liu, Jie;
Kim, Kyoung-Han;
London, Barry;
Morales, Michael;
Backx, Peter

Publication type:

Article

Stabilised beta-catenin in postnatal ventricular myocardium leads to dilated cardiomyopathy and premature death.

Published in:

Basic Research in Cardiology, 2010, v. 105, n. 5, p. 597, doi. 10.1007/s00395-010-0101-8

By:

Hirschy, Alain;
Croquelois, Adrien;
Perriard, Evelyne;
Schoenauer, Roman;
Agarkova, Irina;
Hoerstrup, Simon P.;
Taketo, Makoto M.;
Pedrazzini, Thierry;
Perriard, Jean-Claude;
Ehler, Elisabeth

Publication type:

Article

NO and PGI2 in coronary endothelial dysfunction in transgenic mice with dilated cardiomyopathy.

Published in:

Basic Research in Cardiology, 2008, v. 103, n. 5, p. 417, doi. 10.1007/s00395-008-0723-2

By:

Drelicharz, Lukasz;
Kozlovski, Valery;
Skorka, Tomasz;
Heinze-Paluchowska, Sylwia;
Jasinski, Andrzej;
Gebska, Anna;
Guzik, Tomasz;
Olszanecki, Rafal;
Wojnar, Leszek;
Mende, Ulrike;
Csanyi, Gabor;
Chlopicki, Stefan

Publication type:

Article

Transgenic upregulation of IK1 in the mouse heart is proarrhythmic.

Published in:

2007

By:

Piao, L.;
Li, J.;
McLerie, M.;
Lopatin, A.

Publication type:

Correction Notice

Transgenic upregulation of IK1 in the mouse heart is proarrhythmic.

Published in:

Basic Research in Cardiology, 2007, v. 102, n. 5, p. 416, doi. 10.1007/s00395-007-0659-y

By:

Lin Piao;
Jingdong Li;
McLerie, Meredith;
Lopatin, Anatoli N.

Publication type:

Article

Interstitial remodeling in β1-adrenergic receptor transgenic mice.

Published in:

Basic Research in Cardiology, 2007, v. 102, n. 2, p. 183, doi. 10.1007/s00395-006-0635-y

By:

Seeland, U.;
Selejan, S.;
Engelhardt, S.;
Müller, P.;
Lohse, M.;
Böhm, M.

Publication type:

Article