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Title

A Closed Chemobrionic System as a Biochemical Delivery Platform.

Authors

Angelis, Georgios; Zayed, Dimitris Nabil; Karioti, Anastasia; Lazari, Diamanto; Kanata, Eirini; Sklaviadis, Theodoros; Pampalakis, Georgios

Abstract

Inorganic cells bearing calcium silicate membranes were prepared and resembled closed chemical gardens. It was demonstrated that these inorganic cells can successfully be loaded with natural products, proteins and plasmid DNA, and their cargo can be released in a controlled manner. These cells demonstrated the ability of chemical gardens to act as platforms for the sustained delivery of biomolecules and are expected to introduce chemical gardens in the field of biosciences.

Subjects

NATURAL products; CALCIUM silicates; LIFE sciences; PLASMIDS; GARDENS; SILICATE cements (Dentistry)

Publication

Chemistry - A European Journal, 2019, Vol 25, Issue 56, p12916

ISSN

0947-6539

Publication type

Academic Journal

DOI

10.1002/chem.201903255

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