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- Title
Structure‐Pattern‐Based Total Synthesis.
- Authors
Gerlinger, Christa K. G.; Gaich, Tanja
- Abstract
In this article the concept of structure‐pattern‐recognition and its application to total synthesis is summarized. By applying this synthetic strategy to the two biogenetically unrelated natural product families Sarpagine and Stemona alkaloids, a drastic increase of synthetic efficiency could be achieved. To highlight its potential, this strategy is compared with some elegant target‐oriented syntheses. The importance of strategic planning and synthesis design is clearly demonstrated.
- Subjects
NATURAL products; ALKALOIDS; BIOMIMETIC synthesis; STRATEGIC planning
- Publication
Chemistry - A European Journal, 2019, Vol 25, Issue 46, p10782
- ISSN
0947-6539
- Publication type
Academic Journal
- DOI
10.1002/chem.201901308