Title: Structure‐Pattern‐Based Total Synthesis.
Authors: Gerlinger, Christa K. G.; Gaich, Tanja
Abstract: In this article the concept of structure‐pattern‐recognition and its application to total synthesis is summarized. By applying this synthetic strategy to the two biogenetically unrelated natural product families Sarpagine and Stemona alkaloids, a drastic increase of synthetic efficiency could be achieved. To highlight its potential, this strategy is compared with some elegant target‐oriented syntheses. The importance of strategic planning and synthesis design is clearly demonstrated.
Subjects: NATURAL products; ALKALOIDS; BIOMIMETIC synthesis; STRATEGIC planning
Publication: Chemistry - A European Journal, 2019, Vol 25, Issue 46, p10782
ISSN: 0947-6539
Publication type: Academic Journal
DOI: 10.1002/chem.201901308

Structure‐Pattern‐Based Total Synthesis.

Gerlinger, Christa K. G.; Gaich, Tanja