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- Title
Branched Fatty Acyl Esters of Hydroxyl Fatty Acids (FAHFAs), Appealing Beneficial Endogenous Fat against Obesity and Type‐2 Diabetes.
- Authors
Balas, Laurence; Feillet‐Coudray, Christine; Durand, Thierry
- Abstract
Abstract: After a brief overview of the biological significance of FAHFAs, the present Minireview highlights the different strategies developed for their chemical syntheses. The term “FAHFAs” has been introduced in 2014 for fatty acyl esters of hydroxyl fatty acids, found in adipocytes, with antidiabetic properties. However, many other natural products contain this type of branched lipids in their structure. This review was then extended to the synthesis of these subunits, even though the length of the lipid chains and the location of the ester linkages are different, since the developed strategies may be applied to the synthesis of “FAHFA”.
- Subjects
FATTY acids; TRIGLYCERIDES; CHEMICAL synthesis; CHEMICAL reactions; CARBOXYLIC acids; PALMITIC acid
- Publication
Chemistry - A European Journal, 2018, Vol 24, Issue 38, p9463
- ISSN
0947-6539
- Publication type
Academic Journal
- DOI
10.1002/chem.201800853