Results
Title

Bullous pemphigoid, malignant acanthosis nigricans, and erysipeloid carcinoma in a woman with gastric adenocarcinoma.

Authors

Al‐Zahawi, Saman; Sadeghi, Yasaman; Azhari, Vahidesadat; Mahmoudi, Hamidreza; Daneshpazhooh, Maryam

Abstract

Key Clinical Message: Bullous pemphigoid did not follow the course of Gastric Carcinoma relapse and remisson, unlike the malignant acanthosis nigricans which was in alignment with the paraneoplastic effect of the Gastric Carcinoma. Acanthosis nigricans (AN) is a dermatosis characterized by the presence of hyperpigmented, velvety cutaneous thickening in the flexural areas, posterior neck, and occasionally the extensor surfaces of hand, face, and oral mucosa. AN is commonly associated with insulin resistance, drugs, and rarely internal malignancy (malignant AN). Bullous pemphigoid (BP) is an autoimmune blistering disease characterized by tense blisters involving the skin of mainly elderly patients. The association of BP and malignancy is not well established and the co‐existence of BP with AN has not been reported. Here we report a 58‐year‐old, event‐free gastric adenocarcinoma with three types of skin findings with different pathogenesis‐ BP, malignant AN, and erysipelas‐like metastasis.

Subjects

BULLOUS pemphigoid; ACANTHOSIS nigricans; STOMACH cancer; ADENOCARCINOMA; ORAL mucosa; OLDER patients; AUTOIMMUNE diseases

Publication

Clinical Case Reports, 2024, Vol 12, Issue 1, p1

ISSN

2050-0904

Publication type

Academic Journal

DOI

10.1002/ccr3.8351