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Title

Thrombocytosis as a paraneoplastic syndrome in metastatic malignant peritoneal mesothelioma of biphasic morphology mimicking ovarian adenocarcinoma: A case report.

Authors

Alhamadh, Moustafa S.; Alanazi, Rakan B.; Wadaan, Osama Mohaamad; Alhabeeb, Abdulrahman Yousef; Alkaiyat, Mohammad; Aljarbou, Ohoud Zaid; Sabatin, Fouad

Abstract

Malignant peritoneal mesothelioma (MPM) is a rare malignancy, presenting with non‐specific and potentially‐misleading manifestations. It represents a diagnostic pitfall as it mimics ovarian carcinoma. Maintaining a low diagnostic threshold, obtaining a detailed history, and utilizing immunohistochemical markers to diagnose MPM is crucial as early diagnosis and treatment might improve survival. We report a case of multiple primary malignancies involving malignant peritoneal mesothelioma in a 55‐year‐old female with a remote history of radiotherapy for thyroid papillary adenocarcinoma. Her advanced disease made her unfit for chemotherapy and debulking surgery. She died of cardiac arrest 2 days after palliative care referral.

Subjects

MESOTHELIOMA; ADENOCARCINOMA; THROMBOCYTOSIS; CARDIAC arrest; PLEURA cancer; PALLIATIVE treatment; PARANEOPLASTIC syndromes

Publication

Clinical Case Reports, 2023, Vol 11, Issue 3, p1

ISSN

2050-0904

Publication type

Academic Journal

DOI

10.1002/ccr3.6974

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