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Controlled Ligand Exchange Between Ruthenium Organometallic Cofactor Precursors and a Naïve Protein Scaffold Generates Artificial Metalloenzymes Catalysing Transfer Hydrogenation.
- Published in:
- Angewandte Chemie, 2021, v. 133, n. 19, p. 11014, doi. 10.1002/ange.202015834
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- Publication type:
- Article
"NAD‐display": Ultrahigh‐Throughput in Vitro Screening of NAD(H) Dehydrogenases Using Bead Display and Flow Cytometry.
- Published in:
- Angewandte Chemie, 2021, v. 133, n. 16, p. 9097, doi. 10.1002/ange.202013486
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- Article
Mapping catalytic promiscuity in the alkaline phosphatase superfamily.
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- Pure & Applied Chemistry, 2009, v. 81, n. 4, p. 731, doi. 10.1351/PAC-CON-08-10-20
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- Article
Reverse evolution leads to genotypic incompatibility despite functional and active-site convergence.
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- eLife, 2015, p. 1, doi. 10.7554/eLife.06492
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- Publication type:
- Article
Isothermal DNA amplification using the T4 replisome: circular nicking endonuclease-dependent amplification and primase-based whole-genome amplification.
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- Nucleic Acids Research, 2010, v. 38, n. 22, p. e201, doi. 10.1093/nar/gkq795
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- Article
An efficient method to assemble linear DNA templates for in vitro screening and selection systems.
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- Nucleic Acids Research, 2009, v. 37, n. 18, p. e122, doi. 10.1093/nar/gkp589
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- Article
Droplet-based screening of phosphate transfer catalysis reveals how epistasis shapes MAP kinase interactions with substrates.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28396-4
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- Article
Engineering the protein dynamics of an ancestral luciferase.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23450-z
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- Article
Vector redesign and in‐droplet cell‐growth improves enrichment and recovery in live Escherichia coli.
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- Microbial Biotechnology, 2022, v. 15, n. 11, p. 2845, doi. 10.1111/1751-7915.14144
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- Article
High-throughput total RNA sequencing in single cells using VASA-seq.
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- Nature Biotechnology, 2022, v. 40, n. 12, p. 1780, doi. 10.1038/s41587-022-01361-8
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- Article
One-Pot Deracemization of sec-Alcohols: Enantioconvergent Enzymatic Hydrolysis of Alkyl Sulfates Using Stereocomplementary Sulfatases.
- Published in:
- Angewandte Chemie, 2013, v. 125, n. 11, p. 3359, doi. 10.1002/ange.201209946
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- Publication type:
- Article
Mikrotröpfchen in Mikrofluidiksystemen: eine Technik für Entdeckungen in der Chemie und Biologie.
- Published in:
- Angewandte Chemie, 2010, v. 122, n. 34, p. 5982, doi. 10.1002/ange.200906653
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- Publication type:
- Article
A Shorter Route to Antibody Binders via Quantitative in vitro Bead-Display Screening and Consensus Analysis.
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- Scientific Reports, 2016, p. 36391, doi. 10.1038/srep36391
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- Publication type:
- Article
spinDrop: a droplet microfluidic platform to maximise single-cell sequencing information content.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40322-w
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- Article
Plakoglobin is a mechanoresponsive regulator of naive pluripotency.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39515-0
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- Article
Mutations in <i>Mll2</i>, an H3K4 Methyltransferase, Result in Insulin Resistance and Impaired Glucose Tolerance in Mice.
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- PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0061870
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- Article
An optimized ATP/PP<sub>i</sub>-exchange assay in 96-well format for screening of adenylation domains for applications in combinatorial biosynthesis.
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- Biotechnology Journal, 2007, v. 2, n. 2, p. 232, doi. 10.1002/biot.200600220
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- Article
Intramolecular general acid catalysis of sulfate transfer — Nucleophilic attack by oxyanions on the SO<sub>3</sub><sup>–</sup> group.
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- Canadian Journal of Chemistry, 2005, v. 83, n. 9, p. 1629, doi. 10.1139/V05-172
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- Article
Ultrahigh‐Throughput Detection of Enzymatic Alcohol Dehydrogenase Activity in Microfluidic Droplets with a Direct Fluorogenic Assay.
- Published in:
- ChemBioChem, 2021, v. 22, n. 23, p. 3292, doi. 10.1002/cbic.202100322
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- Article
Specificity Effects of Amino Acid Substitutions in Promiscuous Hydrolases: Context-Dependence of Catalytic Residue Contributions to Local Fitness Landscapes in Nearby Sequence Space.
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- ChemBioChem, 2017, v. 18, n. 11, p. 1001, doi. 10.1002/cbic.201600657
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- Article
Efficient Transfection of siRNA by Peptide Dendrimer-Lipid Conjugates.
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- ChemBioChem, 2016, v. 17, n. 23, p. 2223, doi. 10.1002/cbic.201600485
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- Article
Handicap-Recover Evolution Leads to a Chemically Versatile, Nucleophile-Permissive Protease.
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- ChemBioChem, 2015, v. 16, n. 13, p. 1866, doi. 10.1002/cbic.201500295
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- Article
Flexibility and Reactivity in Promiscuous Enzymes.
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- ChemBioChem, 2013, v. 14, n. 3, p. 285, doi. 10.1002/cbic.201200628
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- Article
SNAP Dendrimers: Multivalent Protein Display on Dendrimer-Like DNA for Directed Evolution.
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- ChemBioChem, 2011, v. 12, n. 14, p. 2208, doi. 10.1002/cbic.201100240
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- Article
Biochemistry: Enzymes under the nanoscope.
- Published in:
- Nature, 2008, v. 456, n. 7218, p. 45, doi. 10.1038/456045a
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- Article
Long‐Term Perfusion Culture of Monoclonal Embryonic Stem Cells in 3D Hydrogel Beads for Continuous Optical Analysis of Differentiation.
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- Small, 2019, v. 15, n. 5, p. N.PAG, doi. 10.1002/smll.201804576
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- Publication type:
- Article
Directed evolution of a histone acetyltransferase – enhancing thermostability, whilst maintaining catalytic activity and substrate specificity.
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- FEBS Journal, 2008, v. 275, n. 22, p. 5635, doi. 10.1111/j.1742-4658.2008.06689.x
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- Publication type:
- Article
Ultrahigh-throughput discovery of promiscuous enzymes by picodroplet functional metagenomics.
- Published in:
- Nature Communications, 2015, v. 6, n. 12, p. 10008, doi. 10.1038/ncomms10008
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- Publication type:
- Article
Controlled Ligand Exchange Between Ruthenium Organometallic Cofactor Precursors and a Naïve Protein Scaffold Generates Artificial Metalloenzymes Catalysing Transfer Hydrogenation.
- Published in:
- Angewandte Chemie International Edition, 2021, v. 60, n. 19, p. 10919, doi. 10.1002/anie.202015834
- By:
- Publication type:
- Article
"NAD‐display": Ultrahigh‐Throughput in Vitro Screening of NAD(H) Dehydrogenases Using Bead Display and Flow Cytometry.
- Published in:
- Angewandte Chemie International Edition, 2021, v. 60, n. 16, p. 9015, doi. 10.1002/anie.202013486
- By:
- Publication type:
- Article
Combining Medium Effects and Cofactor Catalysis: Metal-Coordinated Synzymes Accelerate Phosphate Transfer by 10<sup>8</sup>.
- Published in:
- Chemistry - A European Journal, 2009, v. 15, n. 45, p. 12371, doi. 10.1002/chem.200802616
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- Article
The biosynthesis, degradation, and function of cell wall β‐xylosylated xyloglucan mirrors that of arabinoxyloglucan.
- Published in:
- New Phytologist, 2023, v. 240, n. 6, p. 2353, doi. 10.1111/nph.19305
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- Article
Fluid Phase Endocytosis Contributes to Transfection of DNA by PEI-25.
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- Molecular Therapy, 2009, v. 17, n. 8, p. 1411, doi. 10.1038/mt.2009.121
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- Article
Split & mix assembly of DNA libraries for ultrahigh throughput on-bead screening of functional proteins.
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- Nucleic Acids Research, 2020, v. 48, n. 11, p. e63, doi. 10.1093/nar/gkaa270
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- Article
Combinatorial Synthesis of Structurally Diverse Triazole-Bridged Flavonoid Dimers and Trimers.
- Published in:
- Molecules, 2016, v. 21, n. 9, p. 1230, doi. 10.3390/molecules21091230
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- Article
Monodisperse Water-in-Oil-in-Water (W/O/W) Double Emulsion Droplets as Uniform Compartments for High-Throughput Analysis via Flow Cytometry.
- Published in:
- Micromachines, 2013, v. 4, n. 4, p. 402, doi. 10.3390/mi4040402
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- Publication type:
- Article
Evolution of enzyme catalysts caged in biomimetic gel-shell beads.
- Published in:
- Nature Chemistry, 2014, v. 6, n. 9, p. 791, doi. 10.1038/nchem.1996
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- Publication type:
- Article
A single mutation in the core domain of the lac repressor reduces leakiness.
- Published in:
- Microbial Cell Factories, 2013, v. 12, n. 1, p. 1, doi. 10.1186/1475-2859-12-67
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- Article
Mapping the Limits of Substrate Specificity of the Adenylation Domain of TycA.
- Published in:
- ChemBioChem, 2009, v. 10, n. 4, p. 671, doi. 10.1002/cbic.200800553
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- Article
Relating Chemical and Biological Diversity Space: A Tunable System for Efficient Gene Transfection.
- Published in:
- ChemBioChem, 2008, v. 9, n. 12, p. 1960, doi. 10.1002/cbic.200800003
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- Publication type:
- Article
The Human Histone Acetyltransferase P/CAF is a Promiscuous Histone Propionyltransferase.
- Published in:
- ChemBioChem, 2008, v. 9, n. 4, p. 499, doi. 10.1002/cbic.200700556
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- Publication type:
- Article
An Integrated Device for Monitoring Time-Dependent in vitro Expression From Single Genes in Picolitre Droplets.
- Published in:
- ChemBioChem, 2008, v. 9, n. 3, p. 439, doi. 10.1002/cbic.200700536
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- Publication type:
- Article
Cover Picture: A Covalent Chemical Genotype-Phenotype Linkage for in vitro Protein Evolution (ChemBioChem 18/2007).
- Published in:
- ChemBioChem, 2007, v. 8, n. 18, p. 2173, doi. 10.1002/cbic.200790064
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- Publication type:
- Article
A Covalent Chemical Genotype-Phenotype Linkage for in vitro Protein Evolution.
- Published in:
- ChemBioChem, 2007, v. 8, n. 18, p. 2191, doi. 10.1002/cbic.200700459
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- Publication type:
- Article
European Symposium of Bio-Organic Chemistry 2003 (ESBOC): The Evolution of Catalysis.
- Published in:
- ChemBioChem, 2004, v. 5, n. 2, p. 241, doi. 10.1002/cbic.200300796
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- Publication type:
- Article
Off-the-shelf proteins that rival tailor-made antibodies as catalysts.
- Published in:
- Nature, 1996, v. 383, n. 6595, p. 60, doi. 10.1038/383060a0
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- Publication type:
- Article
Investigating host-microbiome interactions by droplet based microfluidics.
- Published in:
- Microbiome, 2020, v. 8, n. 1, p. N.PAG, doi. 10.1186/s40168-020-00911-z
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- Publication type:
- Article
UMI-linked consensus sequencing enables phylogenetic analysis of directed evolution.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-19687-9
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- Publication type:
- Article
Accessing unexplored regions of sequence space in directed enzyme evolution via insertion/deletion mutagenesis.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17061-3
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- Publication type:
- Article
One-Pot Deracemization of sec-Alcohols: Enantioconvergent Enzymatic Hydrolysis of Alkyl Sulfates Using Stereocomplementary Sulfatases.
- Published in:
- Angewandte Chemie International Edition, 2013, v. 52, n. 11, p. 3277, doi. 10.1002/anie.201209946
- By:
- Publication type:
- Article