Works matching DE "TUMOR microenvironment"

Results: 5000

Senescence-associated secretory phenotype in lung cancer: remodeling the tumor microenvironment for metastasis and immune suppression.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1605085

By:

Chen, Chen;
Chen, Ji;
Zhang, Yanling;
Zhang, Qijun;
Shi, Haixia

Publication type:

Article

Transcriptional profiling reveals H.pylori -associated genes induced inflammatory cell infiltration and chemoresistance in gastric cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1592558

By:

Tan, Jinshui;
Wu, Zhengxin;
Liu, Yuankun;
Wang, Wei;
Qin, Wenjuan;
Pan, Guangchao;
Xiong, Yubo;
Ma, Jingsong;
Zhao, Jiabao;
Zhou, Huiwen;
Liu, ZhengJin;
Lu, Haijie;
Zhuo, Huiqin;
Hong, Xuehui

Publication type:

Article

Investigation of GPR137C as a promising novel marker for the progression of prostate cancer through G4 screen and bioinformatics analyses.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1576835

By:

Hou, Yue;
Lu, Haowen;
Chen, Saisai;
Mao, Likai;
Huang, Xuan;
Xu, Feng;
Shu, Chuanjun

Publication type:

Article

The potential of ME1 in guiding immunotherapeutic strategies for ovarian cancer: insights from pan-cancer research.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1571842

By:

Wei, Jiahui;
Wang, Ming;
Xu, Shuiqing;
Tusufuhan, Paizigul;
Wu, Yumei

Publication type:

Article

Novel strategies to overcome tumor immunotherapy resistance using CAR NK cells.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1550652

By:

Guo, Jun-Hui;
Afzal, Ali;
Ahmad, Sadia;
Saeed, Ghazala;
Rehman, Amna;
Saddozai, Umair Ali Khan;
Liu, Lei;
Guo, Shi-Hao;
Ji, Xin-Ying;
Khawar, Muhammad Babar

Publication type:

Article

Research progress of colorectal cancer in genomic and transcriptomic at multi-level.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1533817

By:

Wen, Qinglian;
Han, Shuangyan;
Cui, Yongxia

Publication type:

Article

胶质母细胞瘤微环境中巨噬细胞极化影响因素的研究进展.

Published in:

Journal of Clinical Neurosurgery / Linchuang Shenjingwaike Zazhi, 2025, v. 22, n. 2, p. 219, doi. 10.3969/j.issn.1672-7770.2025.02.017

By:

杨晓雄;
刘轩辰;
张晋伟;
吉宏明;
王春红

Publication type:

Article

Integrated Analysis of Single‐Cell and Bulk RNA‐Sequencing Defines N7‐Methylguanosine (m7G)‐Mediated Modifications' Role in Prognosis and the Tumor Immune Microenvironment in Hepatocellular Carcinoma.

Published in:

Cancer Medicine, 2025, v. 14, n. 11, p. 1, doi. 10.1002/cam4.70992

By:

Liang, Jiahua;
Ma, Mingjian;
Xu, Borui;
Zhong, Cheng;
Zeng, Guangyan;
Lu, Huijiao;
Lai, Jiaming;
Chen, Jiancong

Publication type:

Article

GABRP Mediates GABA‐A Receptor to Shape Tumor Immunosuppressive Microenvironment and Promote Tumor Immune Escape and Corresponding Targeted Therapy.

Published in:

Cancer Medicine, 2025, v. 14, n. 11, p. 1, doi. 10.1002/cam4.70946

By:

Cen, Wu;
Fu, Genyuan;
Wang, Xiaoyu;
Wei, Ruting;
Zhou, Xingwang;
Teng, Wei;
Ling, Yuanguo;
Tang, Jiaze;
Wang, Zhongan;
Chu, Liangzhao

Publication type:

Article

Fibrotic Fortresses and Therapeutic Frontiers: Pancreatic Stellate Cells and the Extracellular Matrix in Pancreatic Cancer.

Published in:

Cancer Medicine, 2025, v. 14, n. 11, p. 1, doi. 10.1002/cam4.70788

By:

Sigirli, Sila;
Karakas, Didem

Publication type:

Article

A macrophage-predominant immunosuppressive microenvironment and therapeutic vulnerabilities in advanced salivary gland cancer.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60421-0

By:

Zuljan, Erika;
von der Emde, Benjamin;
Piwonski, Iris;
Pestana, Ana;
Klinghammer, Konrad;
Mock, Andreas;
Horak, Peter;
Heining, Christoph;
Klauschen, Frederick;
Pretzell, Ina;
Boerries, Melanie;
Brandts, Christian H.;
Kreutzfeldt, Simon;
Teleanu, Maria-Veronica;
Hübschmann, Daniel;
Morris, Luc G. T.;
Heiland, Max;
Keller, Ulrich;
Conrad, Thomas;
Glimm, Hanno

Publication type:

Article

Utilizing cohort-level and individual networks to predict best response in patients with metastatic triple negative breast cancer.

Published in:

NPJ Precision Oncology, 2025, v. 9, n. 1, p. 1, doi. 10.1038/s41698-025-00959-w

By:

Bottomly, Daniel;
Zheng, Christina;
Creason, Allison L.;
Mitri, Zahi I.;
Mills, Gordon B.;
McWeeney, Shannon K.

Publication type:

Article

SGSM1 as a pan-cancer biomarker: multi-omics insights into immune regulation, prognostic value, and therapeutic implications.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02940-2

By:

Wu, Dali;
Zhong, Guanghui;
Liu, Yufeng;
Li, Cuilian;
Yan, Lingfei;
Luo, Yang;
Li, Qing;
Liu, Dawei;
Wang, Tao

Publication type:

Article

Mechanisms of organotropism in breast cancer and predicting metastasis to distant organs using deep learning.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02905-5

By:

Xiao, Meizhu;
Fu, Zhijin;
Li, Yanjiao;
Zhang, Min;
Zhang, Denan;
Liu, Lei;
Jin, Qing;
Chen, Xiujie;
Xie, Hongbo

Publication type:

Article

Circulating chemokines and leukocytes and their impact on breast cancer prognosis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02881-w

By:

de Araújo, Rogério Agenor;
da Luz, Felipe Andrés Cordero;
da Costa Marinho, Eduarda;
Nascimento, Camila Piqui;
da Silva, Ana Cristina Araújo Lemos;
dos Reis Monteiro, Maria Luíza Gonçalves;
Silva, Marcelo José Barbosa

Publication type:

Article

Trends and hotspots in targeted therapy resistance research for renal cell carcinoma: a bibliometric and visualization analysis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02772-0

By:

Wang, Ziqian;
Xie, Xiaodu;
Wang, Ze;
Tang, Peng;
Chen, Jian;
Xu, Jing;
Zhang, Junying;
Xiao, Haiyang;
Zheng, Chongliang;
Jiang, Jun;
Liu, Qiuli;
Lan, Weihua

Publication type:

Article

Engineered allogeneic stem cells orchestrate T lymphocyte–driven immunotherapy in immunosuppressive leptomeningeal brain metastasis.

Published in:

JNCI: Journal of the National Cancer Institute, 2025, v. 117, n. 6, p. 1151, doi. 10.1093/jnci/djaf006

By:

Kanaya, Nobuhiko;
Seddiq, Waleed;
Chen, Kok-Siong;
Kajiwara, Yoshinori;
Lama, Lucia Moreno;
Borges, Paulo;
Kuroda, Shinji;
Wakimoto, Hiroaki;
Shah, Khalid

Publication type:

Article

Emerging Immunotherapy Targets in Early Drug Development.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5394, doi. 10.3390/ijms26115394

By:

Morchón-Araujo, Daniel;
Catani, Greta;
Mirallas, Oriol;
Pretelli, Giulia;
Sánchez-Pérez, Vicky;
Vieito, María;
Braña, Irene;
Pujol-Borrell, Ricardo;
Garralda, Elena;
Hernando-Calvo, Alberto

Publication type:

Article

Dysregulation of the Bone Marrow Microenvironment in Pediatric Tumors: The Role of Extracellular Vesicles in Acute Leukemias and Neuroblastoma.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5380, doi. 10.3390/ijms26115380

By:

D'Amico, Giovanna;
Starace, Rita;
Della Lastra, Martina;
Marimpietri, Danilo;
Dander, Erica;
Morandi, Fabio;
Airoldi, Irma

Publication type:

Article

Molecular Imaging: Unveiling Metabolic Abnormalities in Pancreatic Cancer.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5242, doi. 10.3390/ijms26115242

By:

Wang, Huanyu;
Gui, Yang;
Lv, Ke

Publication type:

Article

Ion Channel–Extracellular Matrix Interplay in Colorectal Cancer: A Network-Based Approach to Tumor Microenvironment Remodeling.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5147, doi. 10.3390/ijms26115147

By:

Terzi, Alberta;
Maqoud, Fatima;
Guido, Davide;
Mallardi, Domenica;
Aloisio, Michelangelo;
Ura, Blendi;
Gualandi, Nicolò;
Russo, Francesco;
Giannelli, Gianluigi

Publication type:

Article

Tumor Microenvironment in Melanoma Brain Metastasis: A New Potential Target?

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5018, doi. 10.3390/ijms26115018

By:

Caruso, Gerardo;
Garcia Moreira, Cristofer Gonzalo;
Iaboni, Edvige;
Tripodo, Massimo;
Ferrarotto, Rosamaria;
Abbritti, Rosaria Viola;
Conte, Luana;
Caffo, Maria

Publication type:

Article

Modulation of the Antitumor Response to Metformin, Caffeine, and Sodium Dichloroacetate by the Hypoxic Microenvironment in Lung Cancer Cells.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5014, doi. 10.3390/ijms26115014

By:

Garcia-Martin, Misael Osmar;
Castillejos-Lopez, Manuel;
Prado-Garcia, Heriberto;
Romero-Garcia, Susana;
Huerta-Cruz, Juan Carlos;
Choreño-Parra, José Alberto;
Gonzalez-Avila, Georgina;
Colín-Godínez, Luz A.;
Paz-Gomez, Daniel;
Carlos-Reyes, Ángeles;
Ruiz, Victor;
Romero, Yair;
Flores-Soto, Edgar;
Rodríguez-Silverio, Juan;
Lara-Lemus, Roberto;
Velázquez-Cruz, Rafael;
Salinas-Lara, Citlaltepetl;
Torres-Espíndola, Luz María;
Gálvez, Arnoldo Aquino

Publication type:

Article

Molecular Insights into Pleural Mesothelioma: Unveiling Pathogenic Mechanisms and Therapeutic Opportunities.

Published in:

Diagnostics (2075-4418), 2025, v. 15, n. 11, p. 1323, doi. 10.3390/diagnostics15111323

By:

Zahiu, Teodora;
Mihu, Carmen Mihaela;
Bosca, Bianca A.;
Mărginean, Mariana;
Mocan, Lavinia Patricia;
Ștefan, Roxana-Adelina;
Suflețel, Rada Teodora;
Mihu, Carina;
Melincovici, Carmen Stanca

Publication type:

Article

Prognostic Significance of Macrophage Phenotypes in Peri-Tumoral Normal Tissue of Early-Stage Breast Cancer.

Published in:

Cells (2073-4409), 2025, v. 14, n. 11, p. 828, doi. 10.3390/cells14110828

By:

Hirschmann, Marcel;
Schnellhardt, Sören;
Rübner, Matthias;
Segelhorst, Sarah;
Ott, Oliver;
Erber, Ramona;
Daniel, Christoph;
Büttner-Herold, Maike;
Gass, Paul;
Fietkau, Rainer;
Distel, Luitpold

Publication type:

Article

Metabolic Reprogramming Triggered by Fluoride in U-87 Glioblastoma Cells: Implications for Tumor Progression?

Published in:

Cells (2073-4409), 2025, v. 14, n. 11, p. 800, doi. 10.3390/cells14110800

By:

Żwierełło, Wojciech;
Maruszewska, Agnieszka;
Skórka-Majewicz, Marta;
Wszołek, Agata;
Gutowska, Izabela

Publication type:

Article

CYR61 as a Potential Biomarker and Target in Cancer Prognosis and Therapies.

Published in:

Cells (2073-4409), 2025, v. 14, n. 11, p. 761, doi. 10.3390/cells14110761

By:

Schenker, Andrew J.;
Ortiz-Hernández, Greisha L.

Publication type:

Article

Identification of a novel anoikis-related gene signature to predict prognosis and tumor microenvironment in intrahepatic cholangiocarcinoma carcinoma.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02840-5

By:

Zhou, Xuan;
Wei, Bai;
Wang, Yan;
Liu, Mingjie;
Guo, Xiangru;
Duan, Yuting

Publication type:

Article

TCF19 expression and significance analysis in breast cancer: integrated bioinformatics analysis and histological validation.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02546-8

By:

Yu, Haiyang;
Wei, Jingjing;
Chen, Qinhao;
Pan, Yueyin;
Qian, Xiaojun;
Pan, Jing;
Sun, Yubei

Publication type:

Article

LINC02888 promotes HGSOC progression and immune evasion via PPIB-mediated stabilization of LAPTM5 mRNA and inhibition of RIG-I-like receptor signaling.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06650-9

By:

Rui, BingJie;
Yang, YanFeng;
Geng, DanBo;
Kuang, ZiTeng;
Mu, TianLi;
Liu, YuXi;
Ren, Bo;
He, RunZe;
Zhang, XiaoWei;
Zhang, YuCi;
Wang, Min

Publication type:

Article

Composite B‑cell lymphoma and extranodal natural killer/T‑cell lymphoma presenting with distinct clone evolution and tumor microenvironment: A report of two cases.

Published in:

Oncology Letters, 2025, v. 30, n. 1, p. N.PAG, doi. 10.3892/ol.2025.15066

By:

Wen, Qiuyue;
Li, Qiuhui;
Yang, Wei;
Chang, Xiaona;
Zhu, Fang;
Pan, Huaxiong;
Zhang, Liling

Publication type:

Article

Hotspots and frontiers of the relationship between gastric cancer and cancer-associated fibroblasts: a bibliometric analysis.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1576696

By:

Hu, Xiangcheng;
Ren, Lingling;
Zhu, Shuyuan;
Shen, Haiping;
Qian, Chengyong;
Chen, Guanglan;
Chen, Fangling

Publication type:

Article

The role of the gut microbiota in shaping the tumor microenvironment and immunotherapy of breast cancer.

Published in:

Frontiers in Microbiology, 2025, p. 1, doi. 10.3389/fmicb.2025.1591745

By:

Ren, Xiaoying;
Zheng, Lixiang;
Huang, Ling;
Zhao, Jiangbo

Publication type:

Article

CyTOF reveals platelet subtype changes predicting the efficacy of combined immunotherapy and targeted therapy in liver cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1538652

By:

Wang, Wenjing;
Liu, Dan;
Wang, Lilin;
Aishan, Maimaitijiang Wubuli;
Chen, Li;
Zheng, Sujun;
Lu, Junfeng

Publication type:

Article

Revolutionising cancer intervention: the repercussions of CAR-T cell therapy on modern oncology practices.

Published in:

Environmental Sciences Europe, 2025, v. 37, p. 1, doi. 10.1007/s12032-025-02783-5

By:

Kamli, Hossam;
Khan, Najeeb Ullah

Publication type:

Article

ATP‐Assisted Electron and Proton Transfer Boosting Redox Metabolism‐Induced Ferroptosis and Apoptosis for Cancer Therapy.

Published in:

Angewandte Chemie, 2025, v. 137, n. 24, p. 1, doi. 10.1002/ange.202504542

By:

An, Shangjie;
Zhen, Wenyao;
Wang, Yue;
Jia, Xiaodan;
Jiang, Xiue

Publication type:

Article

Mass Spectrometry Advances in Analysis of Glioblastoma.

Published in:

Mass Spectrometry Reviews, 2025, v. 44, n. 4, p. 630, doi. 10.1002/mas.21912

By:

Al Shboul, Sofian;
Singh, Ashita;
Kobetic, Renata;
Goodlett, David R.;
Brennan, Paul M.;
Hupp, Ted;
Dapic, Irena

Publication type:

Article

Melanoma innervation, noradrenaline and cancer progression in zebrafish xenograft model.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02523-8

By:

Lorenzini, Francesca;
Marines, Johanna;
Le Friec, Julien;
Do Khoa, Nam;
Nieto, Maria Angela;
Sanchez-Laorden, Berta;
Mione, Maria Caterina;
Fontenille, Laura;
Kissa, Karima

Publication type:

Article

A self-directed Trojanbot-enzymatic nanobot in neutrobot for active target therapy of glioblastoma.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60422-z

By:

Gao, Yuanyuan;
Mao, Meng;
Li, Yue;
Xuan, Mingjun;
Wu, Yingjie;
He, Qiang

Publication type:

Article

Single-cell and transcriptomic analyses reveal the role of PCDH17 in the non-inflammatory tumor microenvironment of pancreatic cancer.

Published in:

Frontiers in Endocrinology, 2025, p. 1, doi. 10.3389/fendo.2025.1559909

By:

Sun, Yong;
Wan, Hong;
Xiong, Jie;
Cao, Kun;
Yang, Dashuai;
Huang, Jun

Publication type:

Article

Impact of irae characteristics on efficacy of consolidative immunotherapy following chemoradiotherapy in locally advanced NSCLC.

Published in:

BMC Pulmonary Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12890-025-03742-6

By:

Wang, Xiufen;
Fu, Xuebing;
Liu, Qiaohong;
Li, Juan;
Ge, Yihui;
Zhang, Jian;
Wang, Shuyun;
Wang, Leirong;
Wang, Dahai;
Sun, Yanxin;
Gan, Yiling;
Sun, Haodong;
Wang, Zhen;
Sun, Yuping;
Gao, Aiqin

Publication type:

Article

Epigenetic regulation of histone modifications in glioblastoma: recent advances and therapeutic insights.

Published in:

Biomarker Research, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40364-025-00788-w

By:

Zhang, Li;
Yang, Yang;
Li, Yanchu;
Wang, Chenyu;
Bian, Chenbin;
Wang, Hongbin;
Wang, Feng

Publication type:

Article

Tumor-associated macrophages contribute to cholangiocarcinoma progression and chemoresistance through activation of ID1.

Published in:

Annals of Hepatology: Official Journal of the Mexican Association of Hepatology, 2025, v. 30, n. 1, p. 1, doi. 10.1016/j.aohep.2024.101773

By:

Yinghao Guo;
Shuangda Miao;
Yun Jin;
Qi Li;
Yihang Wang;
Xiaoxiao Zhang;
Jiangtao Li

Publication type:

Article

Peripheral blood‐derived immune cell counts as prognostic indicators and their relationship with DNA methylation subclasses in glioblastoma patients.

Published in:

Brain Pathology, 2025, v. 35, n. 4, p. 1, doi. 10.1111/bpa.13334

By:

Asey, Benedikt;
Pantel, Tobias F.;
Mohme, Malte;
Zghaibeh, Yahya;
Dührsen, Lasse;
Silverbush, Dana;
Schüller, Ulrich;
Drexler, Richard;
Ricklefs, Franz L.

Publication type:

Article

Prognostic and immune modulatory effects of ammonia-induced cell death in head and neck squamous cell carcinoma.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02508-0

By:

Chengqun, Qian;
Xijun, Wang;
Yangyang, Fan;
Xiaoqin, Yang;
Min, Cheng;
Jun, Xu

Publication type:

Article

Analysis of immune status and prognostic model incorporating lactate metabolism and immune-related genes in clear cell renal cell carcinoma.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02746-2

By:

Wu, Jun;
Wu, Yuqian;
Sun, Yefeng;
You, Jianhang;
Zhang, Wenjie;
Zhao, Tao

Publication type:

Article

High Midkine Expression Correlates with Poor Prognosis and Immune Cell Infiltration in Hepatocellular Carcinoma.

Published in:

International Journal of General Medicine, 2025, v. 18, p. 2567, doi. 10.2147/IJGM.S490409

By:

Yan, Lili;
Lv, Ji;
Xu, Meimei;
Jia, Hongyu;
Li, Shanshan

Publication type:

Article

Targeting PERP promotes anti-tumor immunity in HNSCC by regulating tumor immune microenvironment and metabolic homeostasis.

Published in:

Molecular Cancer, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12943-025-02360-4

By:

Wang, Xueying;
Tian, Yuxi;
Wu, Xiaohong;
Zhu, Yewen;
Chen, Huihong;
Wang, Zeyao;
Liu, Zihan;
Tan, Jiaqi;
Pan, Zhaoyu;
Cao, Jiaoyan;
Li, Zhenjiang;
Zhang, Xin;
Shi, Zhongjie;
Wang, Juncheng;
Liu, Tong

Publication type:

Article

Integrative multi-omics analysis reveals the LncRNA 60967.1–PLCD4–ATRA axis as a key regulator of colorectal cancer progression and immune response.

Published in:

Molecular Cancer, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12943-025-02359-x

By:

Chen, Yiyi;
Zhao, Ningning;
Xu, Lingna;
Jia, Xiya;
Liu, Fang;
Huang, Jian;
Li, Xuhua;
Wang, Yunfei;
Lai, Chuanxi;
Shen, Yanbin;
Wang, Fei;
Lv, Yiming;
Huang, Xuefeng;
Zhang, Fan;
Gu, Hongcang;
Dai, Sheng

Publication type:

Article

Integrated bioinformatics and functional studies identify CDK9 as a potential prognostic biomarker and therapeutic target in AML.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02841-4

By:

Xie, Zhibin;
Xia, Yang;
Li, Zhongyu;
Zhang, Mengmeng;
Tan, Yuanyuan;
Han, Yuqing;
Wang, Meng;
Zhang, Pingping;
Li, Jiajia

Publication type:

Article