Works matching DE "TUMOR microenvironment"

Results: 5000

Deciphering the cellular and molecular landscape of cervical cancer progression through single-cell and spatial transcriptomics.

Published in:

NPJ Precision Oncology, 2025, v. 9, n. 1, p. 1, doi. 10.1038/s41698-025-00948-z

By:

Xia, Peng;
Zhou, Juanhong;
Shen, Rong;
Wang, Degui

Publication type:

Article

Increased STAT3 Phosphorylation in CD4 + T-Cells of Treated Patients with Chronic Lymphocytic Leukemia and Changes in Circulating Regulatory T-Cell Subsets Relative to Tumor Mass Distribution Value and Disease Duration.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1204, doi. 10.3390/biomedicines13051204

By:

Dreisinger, Mojca;
Roškar, Zlatko;
Goropevšek, Aleš;
Zakelšek, Andreja;
Čurič, Sara;
Živko, Nada;
Bevc, Sebastjan;
Homšak, Evgenija

Publication type:

Article

DBI as a Novel Immunotherapeutic Candidate in Colorectal Cancer: Dissecting Genetic Risk and the Immune Landscape via GWAS, eQTL, and pQTL.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1115, doi. 10.3390/biomedicines13051115

By:

Tian, Ting;
Han, Huan;
Huang, Jingtao;
Ma, Jun'e;
Ran, Ruoxi

Publication type:

Article

Lipid-Metabolism-Related Gene Signature Predicts Prognosis and Immune Microenvironment Alterations in Endometrial Cancer.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1050, doi. 10.3390/biomedicines13051050

By:

Wu, Zhangxin;
Nie, Yufei;
Kong, Deshui;
Xue, Lixiang;
He, Tianhui;
Zhang, Kuaile;
Zhang, Jie;
Shang, Chunliang;
Guo, Hongyan

Publication type:

Article

The Prognostic Impact of the Tumor Immune Microenvironment in Synovial Sarcoma: An Immunohistochemical Analysis Using Digital Pathology and Conventional Interpretation.

Published in:

Journal of Personalized Medicine, 2025, v. 15, n. 5, p. 169, doi. 10.3390/jpm15050169

By:

Medina-Ceballos, Emilio;
Giner, Francisco;
Machado, Isidro;
Heras-Morán, Begoña;
Espino, Mónica;
Navarro, Samuel;
Llombart-Bosch, Antonio

Publication type:

Article

Survivin Interference and SurVaxM as an Adjunct Therapy for Glioblastoma Multiforme.

Published in:

Cells (2073-4409), 2025, v. 14, n. 10, p. 755, doi. 10.3390/cells14100755

By:

Elliott, Willie James;
Gurramkonda, Nandini;
Guda, Maheedhara R.;
Tsung, Andrew J.;
Velpula, Kiran K.

Publication type:

Article

Modeling Tumor Microenvironment Complexity In Vitro: Spheroids as Physiologically Relevant Tumor Models and Strategies for Their Analysis.

Published in:

Cells (2073-4409), 2025, v. 14, n. 10, p. 732, doi. 10.3390/cells14100732

By:

Shah, Shrey;
D'Souza, Gerard G. M.

Publication type:

Article

Unconventional T Cells' Role in Cancer: Unlocking Their Hidden Potential to Guide Tumor Immunity and Therapy.

Published in:

Cells (2073-4409), 2025, v. 14, n. 10, p. 720, doi. 10.3390/cells14100720

By:

Pinco, Paola;
Facciotti, Federica

Publication type:

Article

Exosome-Mediated Chemoresistance in Cancers: Mechanisms, Therapeutic Implications, and Future Directions.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 685, doi. 10.3390/biom15050685

By:

Liu, Gengqi;
Liu, Jingang;
Li, Silu;
Zhang, Yumiao;
He, Ren

Publication type:

Article

The Role of Cancer Organoids in Ferroptosis, Pyroptosis, and Necroptosis: Functions and Clinical Implications.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 659, doi. 10.3390/biom15050659

By:

Lu, Dingci;
Xia, Bingqian;
Feng, Tianquan;
Qi, Gui;
Ma, Zhaowu

Publication type:

Article

Bolstering CD8 + T Cells' Antitumor Immunity: A Promising Strategy to Improve the Response to Advanced Prostate Cancer Treatment.

Published in:

Biology (2079-7737), 2025, v. 14, n. 5, p. 544, doi. 10.3390/biology14050544

By:

Dang, Beijing;
Liang, Lixin;
Li, Zhijun;
Luo, Junli;
Zhong, Shangwei

Publication type:

Article

The impact of gliomas on the normal brain microenvironment: a pilot study.

Published in:

Journal of Histotechnology, 2025, v. 48, n. 2, p. 93, doi. 10.1080/01478885.2024.2408505

By:

Riha, Nicole;
Moore, Jacen S.;
Criswell, Sheila

Publication type:

Article

Pathways and outputs orchestrated in tumor microenvironment cells by hypoxia-induced tumor-derived exosomes in pan-cancer.

Published in:

Cellular Oncology (2211-3428), 2025, v. 48, n. 3, p. 539, doi. 10.1007/s13402-025-01042-z

By:

Capik, Ozel;
Karatas, Omer Faruk

Publication type:

Article

Unraveling the immune evasion mechanisms in the tumor microenvironment of head and neck squamous cell carcinoma.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1597202

By:

Zhao, Xuri;
Zhu, Yaping;
He, Youya;
Gu, Weiyan;
Zhou, Qi;
Jin, Bei;
Chen, Shenguo;
Lin, Haisheng

Publication type:

Article

Molecular subtypes based on ferroptosis-related genes and tumor microenvironment infiltration characterization in small cell lung cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1574434

By:

Wang, Xin;
Xu, Zhenyi;
Lin, Zhen;
Wu, Dawei;
Tang, Yu;
Pei, Zhihua;
Gao, Yibo;
He, Jie

Publication type:

Article

Intercellular communication between FAP+ fibroblasts and SPP1+ macrophages in prostate cancer via multi-omics.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1560998

By:

Wu, Tingting;
Li, Xinyu;
Zheng, Fei;
Liu, Hanchao;
Yu, Yang

Publication type:

Article

Tumor-infiltrating immune cells state-implications for various breast cancer subtypes.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1550003

By:

Xu, Tianshuang;
Zhang, Hongjun;
Yang, Burton B.;
Qadir, Javeria;
Yuan, Hui;
Ye, Ting

Publication type:

Article

Neutrophil-Camouflaged Stealth Liposomes for Photothermal-Induced Tumor Immunotherapy Through Intratumoral Bacterial Activation.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 614, doi. 10.3390/pharmaceutics17050614

By:

Chen, Xinxin;
Sun, Jiang;
Ye, Tingxian;
Li, Fanzhu

Publication type:

Article

Nano-Drug Delivery Systems for Bone Metastases: Targeting the Tumor–Bone Microenvironment.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 603, doi. 10.3390/pharmaceutics17050603

By:

Bakir, Mohamad;
Dawalibi, Ahmad;
Mufti, Mohammad Alaa;
Behiery, Ayman;
Mohammad, Khalid S.

Publication type:

Article

Harnessing the Power of Nanocarriers to Exploit the Tumor Microenvironment for Enhanced Cancer Therapy.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 5, p. 746, doi. 10.3390/ph18050746

By:

Aldhubiab, Bandar;
Almuqbil, Rashed M.;
Nair, Anroop B.

Publication type:

Article

Sindbis Virus Platform Provides an Oncolytic-Virus-Mediated and Immunotherapeutic Strategy to Overcome the Challenging Microenvironment of Pancreatic Cancer.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 5, p. 725, doi. 10.3390/ph18050725

By:

Opp, Silvana;
Pampeno, Christine;
Hurtado, Alicia;
Meruelo, Daniel

Publication type:

Article

Competitive Endogenous RNA Network Involving Immune Subgroups, Infiltration, and lncRNAs in Prostate Cancer.

Published in:

Genes, 2025, v. 16, n. 5, p. 527, doi. 10.3390/genes16050527

By:

Niu, Wenkang;
Zhang, Tingting;
Ma, Lei

Publication type:

Article

Gut Bacteria-Based Cancer Therapy and Anti-Solid Tumor Mechanisms.

Published in:

Microbiology Research, 2025, v. 16, n. 5, p. 92, doi. 10.3390/microbiolres16050092

By:

Zhang, Tianzhu;
Yu, Xiao-Mei;
Yang, Shang-Tian;
Zhou, Wen-Wen

Publication type:

Article

The Spatial Proximity of CD8 + FoxP3 + PD-1 + Cells to Tumor Cells: A More Accurate Predictor of Immunotherapy Outcomes in Advanced Non-Small-Cell Lung Cancer.

Published in:

Current Oncology, 2025, v. 32, n. 5, p. 262, doi. 10.3390/curroncol32050262

By:

Hu, Zijuan;
Hu, Zhihuang;
Chen, Keji;
Huang, Huixia;
Zhong, Xinyang;
Wang, Yaxian;
Chen, Jiayu;
He, Xuefeng;
Shi, Di;
Zeng, Yupeng;
Li, Jiwei;
Zhou, Xiaoyan;
Wei, Ping

Publication type:

Article

Human Herpes Virus Genotype and Immunological Gene Expression Profile in Prostate Cancer with Prominent Inflammation.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4945, doi. 10.3390/ijms26104945

By:

Todorova, Elena;
Kavrakova, Anita;
Derimachkovski, Goran;
Georgieva, Bilyana;
Odzhakov, Feodor;
Bachurska, Svitlana;
Terziev, Ivan;
Boyadzhieva, Maria-Elena;
Valkov, Trifon;
Popov, Elenko;
Slavov, Chavdar;
Tourtourikov, Ivan;
Mitev, Vanyo;
Todorova, Albena

Publication type:

Article

CD71-Mediated Effects of Soluble Vasorin on Tumor Progression, Angiogenesis and Immunosuppression.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4913, doi. 10.3390/ijms26104913

By:

Zhao, Yuechao;
Xiao, Can;
Li, Shaohua;
Huang, Aixue;
Li, Hui;
Dong, Jie;
Qu, Qiaoping;
Liu, Xuemei;
Gao, Bo;
Shao, Ningsheng

Publication type:

Article

Inhibition of MCP1 (CCL2) Enhances Antitumor Activity of NK Cells Against HCC Cells Under Hypoxia.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4900, doi. 10.3390/ijms26104900

By:

Lee, Hwan Hee;
Kim, Juhui;
Park, Eunbi;
Kang, Hyojeung;
Cho, Hyosun

Publication type:

Article

Targeting Pathways in Neuroblastoma: Advances in Treatment Strategies and Clinical Outcomes.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4722, doi. 10.3390/ijms26104722

By:

Benchia, Diana;
Bîcă, Ovidiu Daniel;
Sârbu, Ioan;
Savu, Bogdan;
Farcaș, Diana;
Miron, Ingrith;
Postolache, Anca Lavinia;
Cojocaru, Elena;
Abbo, Olivier;
Ciongradi, Carmen Iulia

Publication type:

Article

Proteomic Analysis of Invasive Breast Cancer Cells Treated with CBD Reveals Proteins Associated with the Reversal of Their Epithelial-Mesenchymal Transition Induced by IL-1β.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4721, doi. 10.3390/ijms26104721

By:

García-Morales, Lázaro;
Ríos-Castro, Emmanuel;
Ramírez, José Tapia;
Meza, Isaura

Publication type:

Article

Signature Gene Mutations in Colorectal Cancer: Potential Neoantigens for Cancer Vaccines.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4559, doi. 10.3390/ijms26104559

By:

Yoon, Jaegoo;
Moon, Haeun;
Jeon, Yuna;
Choe, Soohyun;
Yoon, Hyunho

Publication type:

Article

Graphene Nanocomposites in the Targeting Tumor Microenvironment: Recent Advances in TME Reprogramming.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4525, doi. 10.3390/ijms26104525

By:

Kolokithas-Ntoukas, Argiris;
Mouikis, Andreas;
Angelopoulou, Athina

Publication type:

Article

3D In Vitro Glioma‐Neuron‐Astrocyte Biomimetic Composites Recapitulate Key Molecular Mechanisms Linked to Glioblastoma Multiforme Pathophysiology.

Published in:

Advanced Functional Materials, 2025, v. 35, n. 22, p. 1, doi. 10.1002/adfm.202419211

By:

Mier, Mateo S. Andrade;
Türker, Esra;
Faber, Jessica;
Friedrich, Mike;
Lamberger, Zan;
Weigelt, Jeannette;
Suwannakot, Panthipa;
Gantert, Benedikt;
Singh, Abhinav;
Moessler, Vanessa;
Sodmann, Annemarie;
Murenu, Nicoletta;
Schenk, Joachim;
Schaefer, Natascha;
Blunk, Torsten;
Boccaccini, Aldo R.;
Lühmann, Tessa C.;
Tessmar, Jörg;
Crook, Jeremy M.;
Tomaskovic‐Crook, Eva

Publication type:

Article

VSV-CHIKV activates antitumor immunity by inducing pyroptosis in a melanoma model.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02788-6

By:

Wu, Fan;
Zhan, Ying;
Wang, Siyu;
Wang, Xiaoke;
Hui, Min;
Zhang, Jian;
Zhang, Jing;
Yang, Hongxu;
Lei, Yingfeng;
Yu, Shibin

Publication type:

Article

A phase II study of induction PD-1 blockade (nivolumab) in patients with surgically completely resectable mismatch repair deficient endometrial cancer (NIVEC).

Published in:

Journal of Gynecologic Oncology, 2025, v. 36, n. 3, p. 1, doi. 10.3802/jgo.2025.36.e35

By:

Yong Jae Lee;
Yoo-Young Lee;
Jeong-Yeol Park;
Hyun-Woong Cho;
Myong Cheol Lim;
Mi Kyung Kim;
Jong-Min Lee;
Jung-Yun Lee

Publication type:

Article

Comprehensive Profiling of Acral Lentiginous Melanoma Reveals Downregulated Immune Activation Compared to Cutaneous Melanoma.

Published in:

Pigment Cell & Melanoma Research, 2025, v. 38, n. 3, p. 1, doi. 10.1111/pcmr.70027

By:

Wang, Stephanie J.;
Xiu, Joanne;
Butcher, Katherine M.;
DeClerck, Brittney K.;
Kim, Gene H.;
Moser, Justin;
Gibney, Geoffrey T.;
Hernandez‐Aya, Leonel F.;
Lutzky, Jose;
Abdulla, Farah;
Margolin, Kim A.;
Possik, Patrícia Abrão;
Robles‐Espinoza, Carla Daniela;
Ito, Fumito;
In, Gino K.

Publication type:

Article

HIF-1α and SOX2 expression in cervical squamous cell carcinoma.

Published in:

Vojnosanitetski Pregled: Military Medical & Pharmaceutical Journal of Serbia, 2019, v. 76, n. 12, p. 1253, doi. 10.2298/VSP171213043M

By:

Milenković, Svetlana V.;
Terzić, Tatjana;
Vraneš, Boris;
Soldatović, Ivan

Publication type:

Article

The neutral red assay can be used to evaluate cell viability during autophagy or in an acidic microenvironment in vitro.

Published in:

Biotechnic & Histochemistry, 2021, v. 96, n. 4, p. 302, doi. 10.1080/10520295.2020.1802065

By:

Gomez-Gutierrez, Jorge G.;
Bhutiani, Neal;
McNally, Molly W.;
Chuong, Phillip;
Yin, Wenyuan;
Jones, Meredith A.;
Zeiderman, Matthew R.;
Grizzle, William E.;
McNally, Lacey R.

Publication type:

Article

Cover Image.

Published in:

Veterinary & Comparative Oncology, 2024, v. 22, n. 4, p. 1, doi. 10.1111/vco.13031

By:

Eto, Shotaro;
Kato, Daiki;
Saeki, Kohei;
Iguchi, Takaaki;
Shiyu, Qin;
Kamoto, Satoshi;
Yoshitake, Ryohei;
Shinada, Masahiro;
Ikeda, Namiko;
Tsuboi, Masaya;
Chambers, James;
Uchida, Kazuyuki;
Nishimura, Ryohei;
Nakagawa, Takayuki

Publication type:

Article

Evaluation of Serum Level of Chemokine (C‐C Motif) Ligand 2 (CCL2) in Canine Urothelial Carcinomas, Mast Cell Tumours, and Insulinomas, and Its Correlation With Circulating Monocytes.

Published in:

Veterinary & Comparative Oncology, 2025, v. 23, n. 2, p. 300, doi. 10.1111/vco.13056

By:

Shimizu, Naomi;
Hamaide, Annick;
Noël, Stéphanie;
Clercx, Cécile;
Teske, Erik

Publication type:

Article

PD‐L1, PD‐1, and CTLA‐4 mRNA In Situ Expression by Canine Oral Melanoma Cells and Immune Cells of the Tumour Microenvironment.

Published in:

Veterinary & Comparative Oncology, 2025, v. 23, n. 2, p. 141, doi. 10.1111/vco.13039

By:

Foiani, Greta;
Melchiotti, Erica;
Capello, Katia;
Porcellato, Ilaria;
Brachelente, Chiara;
Iussich, Selina;
Giacobino, Davide;
Morello, Emanuela;
Martano, Marina;
Buracco, Paolo;
Vascellari, Marta

Publication type:

Article

Macrophage Colony Stimulating Factor (M‐CSF) and Interleukin‐34 (IL‐34) Expression in Canine Osteosarcoma in the Context of the Tumour Immune Microenvironment.

Published in:

Veterinary & Comparative Oncology, 2024, v. 22, n. 4, p. 480, doi. 10.1111/vco.12993

By:

Robinson, Christopher J.;
Moeller, Cambri E.;
Quick, Cally N.;
Goodermuth, Christine E.;
Carossino, Mariano;
Withers, Sita S.

Publication type:

Article

Comprehensive Analysis of the Tumour Immune Microenvironment in Canine Urothelial Carcinoma Reveals Immunosuppressive Mechanisms Induced by the COX–Prostanoid Cascade.

Published in:

Veterinary & Comparative Oncology, 2024, v. 22, n. 4, p. 500, doi. 10.1111/vco.12999

By:

Eto, Shotaro;
Kato, Daiki;
Saeki, Kohei;
Iguchi, Takaaki;
Shiyu, Qin;
Kamoto, Satoshi;
Yoshitake, Ryohei;
Shinada, Masahiro;
Ikeda, Namiko;
Tsuboi, Masaya;
Chambers, James;
Uchida, Kazuyuki;
Nishimura, Ryohei;
Nakagawa, Takayuki

Publication type:

Article

The role of companion animal models in radiopharmaceutical development and translation.

Published in:

Veterinary & Comparative Oncology, 2024, v. 22, n. 2, p. 165, doi. 10.1111/vco.12969

By:

Maitz, Charles A.;
Bryan, Jeffrey N.

Publication type:

Article

Inhibitory checkpoint molecule mRNA expression in canine soft tissue sarcoma.

Published in:

Veterinary & Comparative Oncology, 2023, v. 21, n. 4, p. 709, doi. 10.1111/vco.12934

By:

Stevenson, Valentina Beatriz;
Gudenschwager‐Basso, Erwin Kristobal;
Klahn, Shawna;
LeRoith, Tanya;
Huckle, William R.

Publication type:

Article

Tumour necrosis factor stimulated gene 6 intrinsically regulates PD‐L1 expressions in breast cancer cells, leading to modulation of tumour microenvironment.

Published in:

Veterinary & Comparative Oncology, 2023, v. 21, n. 2, p. 255, doi. 10.1111/vco.12884

By:

Lee, Jeong‐Hwa;
An, Ju‐Hyun;
Youn, Hwa‐Young

Publication type:

Article

Expression of the hedgehog signalling pathway and the effect of inhibition at the level of smoothened in canine osteosarcoma cell lines.

Published in:

Veterinary & Comparative Oncology, 2022, v. 20, n. 4, p. 778, doi. 10.1111/vco.12828

By:

Nam, Aryung;
Song, Woo‐Jin;
An, Ju‐Hyun;
Rebhun, Robert B.;
Youn, Hwa‐Young;
Seo, Kyoung‐Won

Publication type:

Article

Preliminary investigation of extracellular vesicles in mammary cancer of dogs and cats: Identification and characterization.

Published in:

Veterinary & Comparative Oncology, 2018, v. 16, n. 4, p. 489, doi. 10.1111/vco.12405

By:

Sammarco, A.;
Finesso, G.;
Cavicchioli, L.;
Ferro, S.;
Caicci, F.;
Zanetti, R.;
Sacchetto, R.;
Zappulli, V.

Publication type:

Article

NIR Light‐Activated and RGD‐Conjugated Ultrasmall Fe/PPy Nanopolymers for Enhanced Tumor Photothermal Ferrotherapy and MR Imaging.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 66, p. 1, doi. 10.1002/chem.202302125

By:

Zhang, Xu;
Wang, Teng;
Zhou, Zijian;
Zhao, Tingting;
Shen, Yuxian;
Fang, Weijun

Publication type:

Article

Confinement of Assemblies of Peptides by Chemical Reactions in Living Cells.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 14, p. 1, doi. 10.1002/chem.202203145

By:

Yang, Xuejiao;
Lu, Honglei;
Kong, Nan;
Wang, Huaimin

Publication type:

Article

Frontispiece: Tumor Microenvironment Responsive Single‐Atom Nanozymes for Enhanced Antitumor Therapy.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 15, p. 1, doi. 10.1002/chem.202281562

By:

Chang, Mengyu;
Hou, Zhiyao;
Wang, Man;
Li, Chunxia;
Al Kheraif, Abdulaziz A.;
Lin, Jun

Publication type:

Article