Works matching DE "TUMOR suppressor genes"

Results: 5000

Epigenetic Therapies in Melanoma—Targeting DNA Methylation and Histone Modification.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1188, doi. 10.3390/biomedicines13051188

By:

Tigu, Adrian Bogdan;
Ivancuta, Andrei;
Uhl, Andrada;
Sabo, Alexandru Cristian;
Nistor, Madalina;
Mureșan, Ximena-Maria;
Cenariu, Diana;
Timis, Tanase;
Diculescu, Doru;
Gulei, Diana

Publication type:

Article

Circular Nucleic Acids Act as an Oncogenic MicroRNA Sponge to Inhibit Hepatocellular Carcinoma Progression.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1171, doi. 10.3390/biomedicines13051171

By:

Zhang, Qianyi;
Sun, Pengcheng;
Hu, Guang;
Yu, Xuanyao;
Zhang, Wen;
Feng, Xuan;
Yu, Lan;
Zhang, Pengfei

Publication type:

Article

Uncovering a Novel Role of ROR1 in the Epigenetic Regulation of Tumor Suppressor Gene CREB3L1 in Triple-Negative Breast Cancer Cells.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 734, doi. 10.3390/biom15050734

By:

Reed, Victoria L.;
Lalu, Eric;
Yoon, Leena;
Fultang, Norman;
Peethambaran, Bela

Publication type:

Article

Radon Exposure and Cancer Risk: Assessing Genetic and Protein Markers in Affected Populations.

Published in:

Biology (2079-7737), 2025, v. 14, n. 5, p. 506, doi. 10.3390/biology14050506

By:

Kashkinbayev, Yerlan;
Kazhiyakhmetova, Baglan;
Altaeva, Nursulu;
Bakhtin, Meirat;
Tarlykov, Pavel;
Saifulina, Elena;
Aumalikova, Moldir;
Ibrayeva, Danara;
Bolatov, Aidos

Publication type:

Article

Metachronous colorectal cancer risks after extended or segmental resection in MLH1, MSH2, and MSH6 Lynch syndrome: multicentre study from the Prospective Lynch Syndrome Database.

Published in:

British Journal of Surgery, 2025, v. 112, n. 4, p. 1, doi. 10.1093/bjs/znaf061

By:

Zalevskaja, K;
Ojala, K;
Petrov, A;
Haupt, S;
Sunde, L;
Bernstein, I;
Jenkins, M A;
Aretz, S;
Nielsen, M;
Capella, G;
Balaguer, F;
Evans, D G;
Burn, J;
Holinski-Feder, E;
Bertario, L;
Bonanni, B;
Lindblom, A;
Levi, Z;
Macrae, F;
Winship, I

Publication type:

Article

Advancements in Gene Therapy for Non-Small Cell Lung Cancer: Current Approaches and Future Prospects.

Published in:

Genes, 2025, v. 16, n. 5, p. 569, doi. 10.3390/genes16050569

By:

Ziółkowska-Suchanek, Iwona;
Rozwadowska, Natalia

Publication type:

Article

Dysregulation of Locus-Specific Repetitive Elements in TCGA Pan-Cancers.

Published in:

Genes, 2025, v. 16, n. 5, p. 528, doi. 10.3390/genes16050528

By:

Wang, Chao;
Liang, Chun

Publication type:

Article

The Basis for Targeting the Tumor Macrophage Compartment in Glioblastoma Immunotherapy.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1631, doi. 10.3390/cancers17101631

By:

Eckert, Thomas;
Walton, Chase;
Bell, Marcus;
Small, Coulter;
Rowland, Nathan C.;
Rivers, Charlotte;
Zukas, Alicia;
Lindhorst, Scott;
Fecci, Peter;
Strickland, Ben A.

Publication type:

Article

Molecular Mechanisms of Drug Resistance in Clear Cell Renal Cell Carcinoma.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1613, doi. 10.3390/cancers17101613

By:

Bianchi, Nicoletta;
Ancona, Pietro;
Aguiari, Gianluca

Publication type:

Article

The Central Role of Ribosomal Proteins in p53 Regulation.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1597, doi. 10.3390/cancers17101597

By:

Lindström, Mikael S.

Publication type:

Article

Different Mechanisms in Doxorubicin-Induced Neurotoxicity: Impact of BRCA Mutations.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4736, doi. 10.3390/ijms26104736

By:

Bhatt, Kriti S.;
Singh, Aman;
Marwaha, Gursharan S.;
Ravendranathan, Naresh;
Sandhu, Inderbir S.;
Kim, Kristen;
Singh, Eesha;
Frisbee, Jefferson C.;
Singh, Krishna K.

Publication type:

Article

Correction: Beylerli et al. MiRNAs as Noninvasive Biomarkers and Therapeutic Agents of Pituitary Adenomas. Int. J. Mol. Sci. 2020, 21 , 7287.

Published in:

2025

By:

Beylerli, Ozal;
Beeraka, Narasimha M.;
Gareev, Ilgiz;
Pavlov, Valentin;
Yang, Guang;
Liang, Yanchao;
Aliev, Gjumrakch

Publication type:

Correction Notice

Therapeutic Potential of Translational Readthrough at Disease‐Associated Premature Termination Codons From Tumor Suppressor Genes.

Published in:

IUBMB Life, 2025, v. 77, n. 5, p. 1, doi. 10.1002/iub.70018

By:

Torices, Leire;
Nunes‐Xavier, Caroline E.;
Pulido, Rafael

Publication type:

Article

Pathogenic TP53 mutations influence chemotherapy response and survival rate of patients with HPV-negative oral carcinomas.

Published in:: Vojnosanitetski Pregled: Military Medical & Pharmaceutical Journal of Serbia, 2022, v. 79, n. 11, p. 1063, doi. 10.2298/VSP200525068J
Publication type:: Article

Isochromosome der(17)(q10)t(15;17) in acute promyelocytic leukemia resulting in an additional copy of the RARA-PML and loss of one p53 gene: report of two cases and literature review.

Published in:

Vojnosanitetski Pregled: Military Medical & Pharmaceutical Journal of Serbia, 2019, v. 76, n. 9, p. 960, doi. 10.2298/VSP170824174D

By:

Djordjević, Vesna;
Fekete, Marija Denčić;
Jovanović, Jelica;
Virijević, Marijana;
Kurtović, Nada Kraguljac;
Jaković, Ljubomir;
Bogdanović, Andrija

Publication type:

Article

Identification of genes in toxicity pathways of trinucleotide-repeat RNA in C. elegans.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 8, p. 712, doi. 10.1038/nsmb.2858

By:

Garcia, Susana M D A;
Tabach, Yuval;
Lourenço, Guinevere F;
Armakola, Maria;
Ruvkun, Gary

Publication type:

Article

A pseudogene long-noncoding-RNA network regulates PTEN transcription and translation in human cells.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 4, p. 440, doi. 10.1038/nsmb.2516

By:

Johnsson, Per;
Ackley, Amanda;
Vidarsdottir, Linda;
Lui, Weng-Onn;
Corcoran, Martin;
Grandér, Dan;
Morris, Kevin V

Publication type:

Article

Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumors.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 12, p. 1331, doi. 10.1038/nsmb.2189

By:

Murga, Matilde;
Campaner, Stefano;
Lopez-Contreras, Andres J;
Toledo, Luis I;
Soria, Rebeca;
Montaña, Maria F;
D'Artista, Luana;
Schleker, Thomas;
Guerra, Carmen;
Garcia, Elena;
Barbacid, Mariano;
Hidalgo, Manuel;
Amati, Bruno;
Fernandez-Capetillo, Oscar

Publication type:

Article

Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 10, p. 1255, doi. 10.1038/nsmb.1916

By:

Dray, Eloïse;
Etchin, Julia;
Wiese, Claudia;
Saro, Dorina;
Williams, Gareth J.;
Hammel, Michal;
Xiong Yu;
Galkin, Vitold E.;
Dongqing Liu;
Miaw-Sheue Tsai;
Sy, Shirley M.-H.;
Schild, David;
Egelman, Edward;
Junjie Chen;
Sung, Patrick

Publication type:

Article

The C terminus of p53 binds the N-terminal domain of MDM2.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 8, p. 982, doi. 10.1038/nsmb.1872

By:

Poyurovsky, Masha V.;
Katz, Chen;
Laptenko, Oleg;
Beckerman, Rachel;
Lokshin, Maria;
Jinwoo Ahn;
Byeon, In-Ja L.;
Gabizon, Ronen;
Mattia, Melissa;
Zupnick, Andrew;
Brown, Lewis M.;
Friedler, Assaf;
Prives, Carol

Publication type:

Article

Role for the MOV10 RNA helicase in Polycomb-mediated repression of the INK4a tumor suppressor.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 7, p. 862, doi. 10.1038/nsmb.1824

By:

Messaoudi-Aubert, Selma El;
Nicholls, James;
Maertens, Goedele N.;
Brookes, Sharon;
Bernstein, Emily;
Peters, Gordon

Publication type:

Article

miR-29 miRNAs activate p53 by targeting p85α and CDC42.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 1, p. 23, doi. 10.1038/nsmb.1533

By:

Seong-Yeon Park;
Jung Hyun Lee;
Minju Ha;
Jin-Wu Nam;
Kim, V. Narry

Publication type:

Article

A YY1–INO80 complex regulates genomic stability through homologous recombination–based repair.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 12, p. 1165, doi. 10.1038/nsmb1332

By:

Su Wu;
Yujiang Shi;
Mulligan, Peter;
Gay, Frédérique;
Landry, Joseph;
Huifei Liu;
Ju Lu;
Qi, Hank H.;
Weijia Wang;
Nickoloff, Jac A.;
Wu, Carl;
Yang Shi

Publication type:

Article

Splicing oncogenes.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 3, p. 174, doi. 10.1038/nsmb0307-174

By:

Hu, Anchang;
Fu, Xiang-Dong

Publication type:

Article

Convergence of Mutation and Epigenetic Alterations Identifies Common Genes in Cancer That Predict for Poor Prognosis.

Published in:

PLoS Medicine, 2008, v. 5, n. 5, p. e114, doi. 10.1371/journal.pmed.0050114

By:

Chan, Timothy A.;
Glockner, Sabine;
Yi, Joo Mi;
Chen, Wei;
Neste, Leander Van;
Cope, Leslie;
Herman, James G.;
Velculescu, Victor;
Schuebel, Kornel E.;
Ahuja, Nita;
Baylin, Stephen B.

Publication type:

Article

Revisiting the Role of miRNAs in Neuropathology.

Published in:

Neurology India, 2025, v. 73, n. 1, p. 1, doi. 10.4103/neurol-india.Neurol-India-D-24-00920

By:

George, Vineetha;
Indira Chandran, Vineesh;
Gopala, Srinivas

Publication type:

Article

Disulfiram ameliorates bleomycin induced pulmonary inflammation and fibrosis in rats.

Published in:

Biotechnic & Histochemistry, 2023, v. 98, n. 8, p. 584, doi. 10.1080/10520295.2023.2261367

By:

Hamidi, Negar;
Feizi, Farideh;
Azadmehr, Abbas;
Zabihi, Ebrahim;
Khafri, Soraya;
Zarei-Behjani, Zeinab;
Babazadeh, Zahra

Publication type:

Article

Expression patterns of human DAB2IP protein in fetal tissues.

Published in:

Biotechnic & Histochemistry, 2012, v. 87, n. 5, p. 350, doi. 10.3109/10520295.2012.664658

By:

Liu, S;
Zhu, N;
Chen, H

Publication type:

Article

mRNA sequencing analysis and growth inhibitory effects of palbociclib on cell lines from canine histiocytic proliferative disorders.

Published in:

Veterinary & Comparative Oncology, 2022, v. 20, n. 3, p. 587, doi. 10.1111/vco.12812

By:

Hirabayashi, Miyuki;
Chambers, James K.;
Tani, Akiyoshi;
Tomiyasu, Hirotaka;
Motegi, Tomoki;
Rimpo, Kenji;
Nakayama, Hiroyuki;
Uchida, Kazuyuki

Publication type:

Article

Genetic variants of BRCA1 and BRCA2 genes in cats with mammary gland carcinoma.

Published in:

Veterinary & Comparative Oncology, 2021, v. 19, n. 2, p. 404, doi. 10.1111/vco.12685

By:

Govoni, Verônica Mollica;
Da Silva, Tereza Cristina;
Guerra, Juliana Mariotti;
Pereira, Isabel Veloso Alves;
Queiroga, Felisbina Luisa;
Cogliati, Bruno

Publication type:

Article

Common germline haplotypes and genotypes identified in BRCA2 exon 11 of dogs with mammary tumours and histopathological analyses.

Published in:

Veterinary & Comparative Oncology, 2018, v. 16, n. 3, p. 379, doi. 10.1111/vco.12389

By:

Maués, T.;
El‐jaick, K. B.;
Costa, F. B.;
Araujo, G. E. F.;
Soares, M. V. G.;
Moreira, A. S.;
Ferreira, M. L. G.;
Ferreira, A. M. R.

Publication type:

Article

Prognostic significance of hypermethylation of death‐associated protein kinase (DAPK) gene CpG island in dogs with high‐grade B‐cell lymphoma.

Published in:

Veterinary & Comparative Oncology, 2018, v. 16, n. 3, p. 409, doi. 10.1111/vco.12395

By:

Sato, M.;
Mochizuki, H.;
Goto‐koshino, Y.;
Fujiwara‐igarashi, A.;
Takahashi, M.;
Ohno, K.;
Tsujimoto, H.

Publication type:

Article

Properties of the feline tumour suppressor reduced expression in immortalized cells ( REIC/Dkk-3).

Published in:

Veterinary & Comparative Oncology, 2017, v. 15, n. 4, p. 1181, doi. 10.1111/vco.12254

By:

Ochiai, K.;
Oda, H.;
Shono, S.;
Kato, Y.;
Sugihara, S.;
Nakazawa, S.;
Azakami, D.;
Michishita, M.;
Onozawa, E.;
Bonkobara, M.;
Sako, T.;
Shun‐Ai, L.;
Ueki, H.;
Watanabe, M.;
Omi, T.

Publication type:

Article

Characterization of HOX gene expression in canine mammary tumour cell lines from spontaneous tumours.

Published in:

Veterinary & Comparative Oncology, 2015, v. 13, n. 3, p. 322, doi. 10.1111/vco.12062

By:

DeInnocentes, P.;
Perry, A. L.;
Graff, E. C.;
Lutful Kabir, F. M.;
Curtis Bird, R.

Publication type:

Article

Epigenetic Anti‐Cancer Treatment With a Stabilized Carbocyclic Decitabine Analogue.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 26, p. 1, doi. 10.1002/chem.202200640

By:

Traube, Franziska R.;
Brás, Natércia F.;
Roos, Wynand P.;
Sommermann, Corinna C.;
Diehl, Tamara;
Mayer, Robert J.;
Ofial, Armin R.;
Müller, Markus;
Zipse, Hendrik;
Carell, Thomas

Publication type:

Article

Dual-Targeting Nanovesicles for In Situ Intracellular Imaging of and Discrimination between Wild-type and Mutant p53.

Published in:

Angewandte Chemie, 2016, v. 128, n. 2, p. 729, doi. 10.1002/ange.201510142

By:

Qian, Ruocan;
Cao, Yue;
Long, Yi ‐ Tao

Publication type:

Article

Dead-End protein expression, function, and mutation in cancer: a systematic review.

Published in:

2025

By:

Faraji, Homa;
Banakar, Farnaz;
Sadri, Arash;
Ebrahim-Habibi, Azadeh

Publication type:

Literature Review

Protein kinase C iota (PKCι) and pVHL are both needed for lysosomal degradation of α5 integrin in renal carcinoma cells.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10272-1

By:

Schurr, Alissa F.;
Dave, Chandni S.;
Shah, Prachi J.;
Meth, Jennifer L.;
Jaramillo, Alexandria S.;
Bartley, Kelly;
Schoenfeld, Alan R.

Publication type:

Article

Aberrant DNA methylation of EDNRB, MGMT and TIMP3 gene promoters in saliva of head and neck carcinoma patients as a diagnostic tool.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10250-7

By:

Shekhawat, Jyoti Kanwar;
Sharma, Jyoti;
Choudhury, Bikram;
Chugh, Ankita;
Purohit, Purvi;
Sharma, Praveen;
Banerjee, Mithu

Publication type:

Article

Role of artificial intelligence in cancer detection using protein p53: A Review.

Published in:

Molecular Biology Reports, 2024, v. 52, n. 1, p. 1, doi. 10.1007/s11033-024-10051-4

By:

Patil, Manisha R.;
Bihari, Anand

Publication type:

Article

DNA hypermethylation of tumor suppressor genes among oral squamous cell carcinoma patients: a prominent diagnostic biomarker.

Published in:

Molecular Biology Reports, 2024, v. 52, n. 1, p. 1, doi. 10.1007/s11033-024-10144-0

By:

Agarwal, Nistha;
Jha, Abhimanyu Kumar

Publication type:

Article

Anti-tumor potential of high salt in breast Cancer cell lines.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09925-4

By:

Sharma, Manoj;
Dey, Upalabdha;
Das, Anindhya Sundar;
Olymon, Kaushika;
Kumar, Aditya;
Mukhopadhyay, Rupak

Publication type:

Article

Association analysis of miRNA-146a and miRNA-196a polymorphism with breast cancer risk in Khyber Pakhtunkhwa, Pakistan: a preliminary study.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09765-2

By:

Hina, Gul I.;
Khan, Najeeb Ullah;
Muntaha, Sidra Tul;
Ullah, Asad;
Khan, Sherhayat;
Alanzi, Abdullah R.;
Ali, Ijaz;
Chen, Tianhui

Publication type:

Article

Overexpression of WT1 in all molecular subtypes of breast cancer and its impact on survival: exploring oncogenic and tumor suppressor roles of distinct WT1 isoforms.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09450-4

By:

Ben Haj Othmen, Hind;
Othman, Houcemeddine;
Khamessi, Oussema;
Bettaieb, Ilhem;
Gara, Sonia;
Kharrat, Maher

Publication type:

Article

CDKN2A promoter methylation enhances self-renewal of glioblastoma stem cells and confers resistance to carmustine.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09247-5

By:

Wang, Jing;
Xi, Yan-feng;
Zhao, Qi;
Guo, Jiang-hong;
Zhang, Zhen;
Zhang, Mao-bai;
Chang, Jiang;
Wu, Yue-qin;
Su, Wen

Publication type:

Article

EZH2-interacting lncRNAs contribute to gastric tumorigenesis; a review on the mechanisms of action.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09237-7

By:

Mohebbi, Hossein;
Esbati, Romina;
Hamid, Ran Abdalsalam;
Akhavanfar, Roozbeh;
Radi, Usama Kadem;
Siri, Goli;
Yazdani, Omid

Publication type:

Article

Adaption of tobacco rattle virus to its solanaceous hosts is related to the codon usage bias of the hosts and that of the viral 16 K gene.

Published in:

European Journal of Plant Pathology, 2023, v. 166, n. 1, p. 91, doi. 10.1007/s10658-023-02641-y

By:

Lin, Qi;
Zheng, Yuanting;
Yin, Yueyan;
Chen, Yi;
Li, Miaomiao;
Zheng, Hongying;
Chen, Jianping;
Yan, Fei;
Lu, Yuwen;
Xu, Shengchun

Publication type:

Article

Human artificial chromosome carrying 3p21.3-p22.2 region suppresses hTERT transcription in oral cancer cells.

Published in:

Chromosome Research, 2023, v. 31, n. 3, p. 1, doi. 10.1007/s10577-023-09726-8

By:

Ohira, Takahito;
Yoshimura, Kaho;
Kugoh, Hiroyuki

Publication type:

Article

Palladium and platinum complexes based on pyridine bases induced anticancer effectiveness via apoptosis protein signaling in cancer cells.

Published in:

BioMetals, 2024, v. 37, n. 4, p. 905, doi. 10.1007/s10534-023-00580-z

By:

El-bendary, Mohamed M.;
Akhdhar, Abdullah;
Al-Bogami, Abdullah S.;
Domyati, Doaa;
Kalantan, Abdulaziz A.;
Alzahrani, Faisal Ay;
Alamoudi, Samer M.;
Sheikh, Ryan A.;
Ali, Ehab M. M.

Publication type:

Article

A Japanese patient with Li-Fraumeni syndrome who had nine primary malignancies associated with a germline mutation of the p53 tumor-suppressor gene.

Published in:

International Journal of Clinical Oncology, 2008, v. 13, n. 1, p. 78, doi. 10.1007/s10147-007-0692-8

By:

Izawa, Naohiro;
Matsumoto, Seiichi;
Manabe, Jun;
Tanizawa, Taisuke;
Hoshi, Manabu;
Shigemitsu, Toshio;
Machinami, Rikuo;
Kanda, Hiroaki;
Takeuchi, Kengo;
Miki, Yoshio;
Arai, Masami;
Shirahama, Shuya;
Kawaguchi, Noriyoshi

Publication type:

Article