Works matching DE "BINDING sites"

Results: 5000

The Role of NMDA Receptor Binding Sites in Ethanol Place Conditioning.

Published in:

2004

By:

Boyce-Rustay, Janel M.;
Cunningham, Christopher L.

Publication type:

Journal Article

A new labdane diterpenoid, in vitro and in silico cytotoxicity, and protease inhibitory effects of phytochemicals from Juniperus polycarposK. Koch leaves.

Published in:

Natural Product Research, 2025, v. 39, n. 11, p. 3053, doi. 10.1080/14786419.2024.2323542

By:

Naderian, Moslem;
Hafez Ghoran, Salar;
Abdjan, Muhammad Ikhlas;
Sabahi, Zahra;
Moein, Soheila;
Jassbi, Amir Reza;
Moein, Mahmoodreza

Publication type:

Article

The Study of Regioselective Acylation of Geniposide by Using Whole-Cell Biocatalysts in Organic Solvents.

Published in:

Catalysts (2073-4344), 2025, v. 15, n. 5, p. 428, doi. 10.3390/catal15050428

By:

Yang, Rongling;
Huang, Ziling;
Zhao, Xiangjie;
Luo, Hongzhen;
Tong, Yuli;
Li, Xiaoyan;
Zhu, Chun;
Wang, Yu;
Sun, Yang

Publication type:

Article

High Affinity Aptamers and Their Specificity for Azaspiracid-2 Using Capture-SELEX.

Published in:

Marine Drugs, 2025, v. 23, n. 5, p. 183, doi. 10.3390/md23050183

By:

Yang, Jiaping;
Li, Xinhao;
Sun, Weiqin;
Cui, Yunyi;
Chen, Han;
Yang, Yao;
Sun, Mingjuan;
Wang, Lianghua

Publication type:

Article

Impedimetric Detection of Breast Cancer‐Related BRCA1 Gene Using Molecular Imprinted Polymer Modified ITO Electrode.

Published in:

Polymers for Advanced Technologies, 2025, v. 36, n. 5, p. 1, doi. 10.1002/pat.70189

By:

Majd, Samira Mansouri;
Mirzapour, Fatemeh;
Shamsipur, Mojtaba

Publication type:

Article

PAX3 Regulatory Signatures and Gene Targets in Melanoma Cells.

Published in:

Genes, 2025, v. 16, n. 5, p. 577, doi. 10.3390/genes16050577

By:

Moore, Stephen P. G.;
Ganesh Krishnan, Shripushkar;
Jaswanth Kothari, Rutu;
Prince, Noah B.;
Kenny, Colin;
Zhang, Chao;
Lang, Deborah

Publication type:

Article

NAC1/ACOX2 Axis as a Novel Therapeutic Target for Endometriosis-Related Ovarian Neoplasms.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4938, doi. 10.3390/ijms26104938

By:

Sonia, Shahataj Begum;
Nakayama, Kentaro;
Razia, Sultana;
Nakayama, Naomi;
Ishikawa, Masako;
Yamashita, Hitomi;
Kanno, Kosuke;
Takeshita, Haruo;
Zahan, Umme Farzana;
Sohel, Hasibul Islam;
Kyo, Satoru

Publication type:

Article

Genome-Wide Characterization of WRKY Gene Family in Camellia chekiangoleosa Identifies Potential Regulatory Components in Pigment Biosynthesis Pathways.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4622, doi. 10.3390/ijms26104622

By:

Liu, Zhenyu;
Peng, Yixuan;
Qu, Yanshu;
Huang, Bin;
Gong, Chun;
Wen, Qiang

Publication type:

Article

A Novel KGD-Based αIIbβ3 Antagonist Prevents Arterial Thrombosis While Preserving Hemostasis and Avoiding Thrombocytopenia.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4530, doi. 10.3390/ijms26104530

By:

Kuo, Yu-Ju;
Chung, Ching-Hu;
Chen, Chun-Chao;
Liu, Ju-Chi;
Chiou, Kuan-Rau;
Sheu, Joen-Rong;
Chuang, Woei-Jer;
Huang, Tur-Fu

Publication type:

Article

DNA‐Binding Properties of Non‐Intercalating Water‐Soluble Organometallic Ir(III) Luminophores.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 30, p. 1, doi. 10.1002/chem.202500290

By:

Alkhaibari, Ibrahim S.;
Horton, Peter N.;
Coles, Simon J.;
Buurma, Niklaas J.;
Pope, Simon J. A.

Publication type:

Article

Structure of a prokaryotic fumarate transporter reveals the architecture of the SLC26 family.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 10, p. 803, doi. 10.1038/nsmb.3091

By:

Geertsma, Eric R;
Chang, Yung-Ning;
Shaik, Farooque R;
Neldner, Yvonne;
Pardon, Els;
Steyaert, Jan;
Dutzler, Raimund

Publication type:

Article

Linker Nups connect the nuclear pore complex inner ring with the outer ring and transport channel.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 10, p. 774, doi. 10.1038/nsmb.3084

By:

Fischer, Jessica;
Teimer, Roman;
Amlacher, Stefan;
Kunze, Ruth;
Hurt, Ed

Publication type:

Article

SEC-uring membrane fusion: a sneak peek at SNARE-complex assembly driven by Sec1-Munc18 proteins.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 10, p. 756, doi. 10.1038/nsmb.3094

By:

Collins, Brett M;
Martin, Jennifer L

Publication type:

Article

Allosteric enhancement of MAP kinase p38α's activity and substrate selectivity by docking interactions.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 8, p. 704, doi. 10.1038/nsmb.2861

By:

Tokunaga, Yuji;
Takeuchi, Koh;
Takahashi, Hideo;
Shimada, Ichio

Publication type:

Article

Dynamics of yeast histone H2A and H2B phosphorylation in response to a double-strand break.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 1, p. 103, doi. 10.1038/nsmb.2737

By:

Lee, Cheng-Sheng;
Lee, Kihoon;
Legube, Gaëlle;
Haber, James E

Publication type:

Article

Good cap/bad cap: how the cap-binding complex determines RNA fate.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 1, p. 9, doi. 10.1038/nsmb.2751

By:

Müller-McNicoll, Michaela;
Neugebauer, Karla M

Publication type:

Article

Structural basis for RNA recognition by a dimeric PPR-protein complex.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 12, p. 1377, doi. 10.1038/nsmb.2710

By:

Ke, Jiyuan;
Chen, Run-Ze;
Ban, Ting;
Zhou, X Edward;
Gu, Xin;
Tan, M H Eileen;
Chen, Chen;
Kang, Yanyong;
Brunzelle, Joseph S;
Zhu, Jian-Kang;
Melcher, Karsten;
Xu, H Eric

Publication type:

Article

Cks confers specificity to phosphorylation-dependent CDK signaling pathways.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 12, p. 1407, doi. 10.1038/nsmb.2707

By:

McGrath, Denise A;
Balog, Eva Rose M;
Kõivomägi, Mardo;
Lucena, Rafael;
Mai, Michelle V;
Hirschi, Alexander;
Kellogg, Douglas R;
Loog, Mart;
Rubin, Seth M

Publication type:

Article

Conformational dynamics of STIM1 activation.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 8, p. 918, doi. 10.1038/nsmb.2647

By:

Feske, Stefan;
Prakriya, Murali

Publication type:

Article

Binding thermodynamics of a glutamate transporter homolog.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 5, p. 634, doi. 10.1038/nsmb.2548

By:

Reyes, Nicolas;
Oh, SeCheol;
Boudker, Olga

Publication type:

Article

BID-induced structural changes in BAK promote apoptosis.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 5, p. 589, doi. 10.1038/nsmb.2563

By:

Moldoveanu, Tudor;
Grace, Christy R;
Llambi, Fabien;
Nourse, Amanda;
Fitzgerald, Patrick;
Gehring, Kalle;
Kriwacki, Richard W;
Green, Douglas R

Publication type:

Article

Pinpointing a puzzling polymerase.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 9, p. 865, doi. 10.1038/nsmb.2374

By:

Mosher, Rebecca A

Publication type:

Article

Dynamic and static components power unfolding in topologically closed rings of a AAA+ proteolytic machine.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 6, p. 616, doi. 10.1038/nsmb.2288

By:

Glynn, Steven E;
Nager, Andrew R;
Baker, Tania A;
Sauer, Robert T

Publication type:

Article

Real-time assembly landscape of bacterial 30S translation initiation complex.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 6, p. 609, doi. 10.1038/nsmb.2285

By:

Milón, Pohl;
Maracci, Cristina;
Filonava, Liudmila;
Gualerzi, Claudio O;
Rodnina, Marina V

Publication type:

Article

PABP and the poly(A) tail augment microRNA repression by facilitated miRISC binding.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 6, p. 603, doi. 10.1038/nsmb.2309

By:

Moretti, Francesca;
Kaiser, Constanze;
Zdanowicz-Specht, Agnieszka;
Hentze, Matthias W

Publication type:

Article

Structure of mammalian poly(ADP-ribose) glycohydrolase reveals a flexible tyrosine clasp as a substrate-binding element.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 6, p. 653, doi. 10.1038/nsmb.2305

By:

Kim, In-Kwon;
Kiefer, James R;
Ho, Chris M W;
Stegeman, Roderick A;
Classen, Scott;
Tainer, John A;
Ellenberger, Tom

Publication type:

Article

Diverse HIV viruses are targeted by a conformationally dynamic antiviral.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 4, p. 411, doi. 10.1038/nsmb.2253

By:

Caines, Matthew E C;
Bichel, Katsiaryna;
Price, Amanda J;
McEwan, William A;
Towers, Greg J;
Willett, Brian J;
Freund, Stefan M V;
James, Leo C

Publication type:

Article

Mechanism of ubiquitylation by dimeric RING ligase RNF4.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 9, p. 1052, doi. 10.1038/nsmb.2108

By:

Plechanovová, Anna;
Jaffray, Ellis G.;
McMahon, Stephen A.;
Johnson, Kenneth A.;
Navrátilová, Iva;
Naismith, James H.;
Hay, Ronald T.

Publication type:

Article

Modular mechanism of Wnt signaling inhibition by Wnt inhibitory factor 1.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 8, p. 886, doi. 10.1038/nsmb.2081

By:

Malinauskas, Tomas;
Aricescu, A. Radu;
Weixian Lu;
Siebold, Christian;
Jones, E. Yvonne

Publication type:

Article

Structure of the no-go mRNA decay complex Dom34-Hbs1 bound to a stalled 80S ribosome.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 6, p. 715, doi. 10.1038/nsmb.2057

By:

Becker, Thomas;
Armache, Jean-Paul;
Jarasch, Alexander;
Anger, Andreas M.;
Villa, Elizabeth;
Sieber, Heidemarie;
Motaal, Basma Abdel;
Mielke, Thorsten;
Berninghausen, Otto;
Beckmann, Roland

Publication type:

Article

Implications of molecular heterogeneity for the cooperativity of biological macromolecules.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 6, p. 732, doi. 10.1038/nsmb.2052

By:

Solomatin, Sergey V.;
Greenfeld, Max;
Herschlag, Daniel

Publication type:

Article

Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 5, p. 564, doi. 10.1038/nsmb.2054

By:

Rochel, Natacha;
Ciesielski, Fabrice;
Godet, Julien;
Moman, Edelmiro;
Roessle, Manfred;
Peluso-Iltis, Carole;
Moulin, Martine;
Haertlein, Michael;
Callow, Phil;
Mély, Yves;
Svergun, Dmitri I.;
Moras, Dino

Publication type:

Article

Structural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 5, p. 604, doi. 10.1038/nsmb.2021

By:

Nguyen, Tina T.;
Shih-Chung Chang;
Evnouchidou, Irini;
York, Ian A.;
Zikos, Christos;
Rock, Kenneth L.;
Goldberg, Alfred L.;
Stratikos, Efstratios;
Stern, Lawrence J.

Publication type:

Article

Structure of the VP16 transactivator target in the Mediator.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 4, p. 410, doi. 10.1038/nsmb.1999

By:

Milbradt, Alexander G.;
Kulkarni, Madhura;
Tingfang Yi;
Takeuchi, Koh;
Sun, Zhen-Yu J.;
Luna, Rafael E.;
Selenko, Philipp;
Näär, Anders M.;
Wagner, Gerhard

Publication type:

Article

Defining an allosteric circuit in the cysteine protease domain of Clostridium difficile toxins.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 3, p. 364, doi. 10.1038/nsmb.1990

By:

Shen, Aimee;
Lupardus, Patrick J.;
Gersch, Malte M.;
Puri, Aaron W.;
Albrow, Victoria E.;
Garcia, K Christopher;
Bogyo, Matthew

Publication type:

Article

The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 10, p. 1266, doi. 10.1038/nsmb.1909

By:

Qing Li;
Jianxun Qi;
Wei Zhang;
Vavricka, Christopher J.;
Yi Shi;
Jinhua Wei;
Enguang Feng;
Jingshan Shen;
Jilong Chen;
Di Liu;
Jianhua He;
Jinghua Yan;
Hong Liu;
Hualiang Jiang;
Maikun Teng;
Xuebing Li;
Gao, George F.

Publication type:

Article

Nonspecifically bound proteins spin while diffusing along DNA.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 12, p. 1224, doi. 10.1038/nsmb.1716

By:

Blainey, Paul C.;
Guobin Luo;
Kou, S. C.;
Mangel, Walter F.;
Verdine, Gregory L.;
Biman Bagchi;
X. Sunney Xie

Publication type:

Article

Two-sided ubiquitin binding explains specificity of the TAB2 NZF domain.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 12, p. 1328, doi. 10.1038/nsmb.1731

By:

Kulathu, Yogesh;
Akutsu, Masato;
Bremm, Anja;
Hofmann, Kay;
Komander, David

Publication type:

Article

How do transcription factors select specific binding sites in the genome?

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 11, p. 1118, doi. 10.1038/nsmb1109-1118

By:

Pan, Yongping;
Tsai, Chung-Jung;
Ma, Buyong;
Nussinov, Ruth

Publication type:

Article

Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 7, p. 698, doi. 10.1038/nsmb.1607

By:

Bishop, Benjamin;
Aricescu, A. Radu;
Harlos, Karl;
O'Callaghan, Chris A.;
Jones, E. Yvonne;
Siebold, Christian

Publication type:

Article

Cancer-associated regulation of alternative splicing.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 6, p. 670, doi. 10.1038/nsmb.1608

By:

Venables, Julian P.;
Klinck, Roscoe;
Koh, ChuShin;
Gervais-Bird, Julien;
Bramard, Anne;
Inkel, Lyna;
Durand, Mathieu;
Couture, Sonia;
Froehlich, Ulrike;
Lapointe, Elvy;
Lucier, Jean-François;
Thibault, Philippe;
Rancourt, Claudine;
Tremblay, Karine;
Prinos, Panagiotis;
Chabot, Benoit;
Elela, Sherif Abou

Publication type:

Article

Antidepressant specificity of serotonin transporter suggested by three LeuT–SSRI structures.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 6, p. 652, doi. 10.1038/nsmb.1602

By:

Zhou, Zheng;
Zhen, Juan;
Karpowich, Nathan K.;
Law, Christopher J.;
Reith, Maarten E. A.;
Wang, Da-Neng

Publication type:

Article

S16 throws a conformational switch during assembly of 30S 5′ domain.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 4, p. 438, doi. 10.1038/nsmb.1585

By:

Ramaswamy, Priya;
Woodson, Sarah A

Publication type:

Article

Helix sliding in the stalk coiled coil of dynein couples ATPase and microtubule binding.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 3, p. 325, doi. 10.1038/nsmb.1555

By:

Kon, Takahide;
Imamula, Kenji;
Roberts, Anthony J.;
Ohkura, Reiko;
Knight, Peter J.;
Gibbons, I. R.;
Burgess, Stan A.;
Sutoh, Kazuo

Publication type:

Article

Helix movement is coupled to displacement of the second extracellular loop in rhodopsin activation.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 2, p. 168, doi. 10.1038/nsmb.1549

By:

Ahuja, Shivani;
Hornak, Viktor;
Yan, Elsa C Y;
Syrett, Natalie;
Goncalves, Joseph A;
Hirshfeld, Amiram;
Ziliox, Martine;
Sakmar, Thomas P;
Sheves, Mordechai;
Reeves, Philip J;
Smith, Steven O;
Eilers, Markus

Publication type:

Article

Ligands bind to Sortilin in the tunnel of a ten-bladed β-propeller domain.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 1, p. 96, doi. 10.1038/nsmb.1543

By:

Quistgaard, Esben M.;
Madsen, Peder;
Grøftehauge, Morten K.;
Nissen, Poul;
Petersen, Claus M.;
Thirup, Søren S.

Publication type:

Article

How does Plasmodium falciparum stick to CSA? Let's see in the crystal.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 9, p. 895, doi. 10.1038/nsmb0908-895

By:

Bentley, Graham A.;
Gamain, Benoît

Publication type:

Article

Structure of the DBL3x domain of pregnancy-associated malaria protein VAR2CSA complexed with chondroitin sulfate A.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 9, p. 932, doi. 10.1038/nsmb.1479

By:

Singh, Kavita;
Gittis, Apostolos G.;
Phuc Nguyen;
Gowda, D. Channe;
Miller, Louis H.;
Garboczi, David N.

Publication type:

Article

Reply to “The binding stoichiometry of CIN85 SH3 domain A and Cbl-b”.

Published in:

2008

By:

Jozic, Daniela;
Cárdenes, Nayra;
Deribe, Yonathan Lissanu;
Moncalián, Gabriel;
Hoeller, Daniela;
Groemping, Yvonne;
Dikic, Ivan;
Rittinger, Katrin;
Bravo, Jerónimo

Publication type:

Letter

A second binding site for double-stranded RNA in TLR3 and consequences for interferon activation.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 7, p. 761, doi. 10.1038/nsmb.1453

By:

Pirher, Nina;
Ivičak, Karolina;
Pohar, Jelka;
Benčina, Mojca;
Jerala, Roman

Publication type:

Article