Results
Title

The effect of highly selective vagotomy on the relationship between gastric mucosal blood flow and acid secretion in man.

Authors

Knight, S. E.; McIsaac, R. L.; Fielding, L. P.

Abstract

Previous work has shown that the duodenal ulcer population can be defined by a lower ratio between gastric mucosal blood flow and acid secretion (during pentagastrin stimulation) than is found in normal subjects. The results of the present investigation have shown that the ratio is restored to normality by highly selective vagotomy. This suggests that increased tonic activity of the vagus on the parietal cell is one of the important disorders in duodenal ulceration.

Publication

British Journal of Surgery, 1978, Vol 65, Issue 10, p721

ISSN

0007-1323

Publication type

Academic Journal

DOI

10.1002/bjs.1800651014