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Title: Investigation of fungicidal activity of 3-piperazine-bis(benzoxaborole) and its boronic acid analogue.
Authors: Wieczorek, Dorota; Lipok, Jacek; Borys, Krzysztof M.; Adamczyk ‐ Woźniak, Agnieszka; Sporzyński, Andrzej
Abstract: 3-Piperazine-bis(benzoxaborole) and its bis(phenylboronic acid) analogue were investigated in terms of their fungicidal activity. The study was carried out against five filamentous fungi: Aspergillus terreus, Fusarium dimerum, Fusarium solani, Penicillium ochrochloron and Aspergillus niger. 3-Piperazine-bis(benzoxaborole) revealed higher inhibitory activity towards the examined strains than standard antibiotic (amphotericin B), whereas bis(phenylboronic acid) proved to be inactive. The study unequivocally showed that the presence of the heterocyclic benzoxaborole system is essential for antifungal action of the examined compounds. Copyright © 2014 John Wiley & Sons, Ltd.
Subjects: FUNGICIDES; PIPERAZINE; BORONIC acids; ASPERGILLUS niger; FUSARIUM solani; ANTIBIOTICS
Publication: Applied Organometallic Chemistry, 2014, Vol 28, Issue 5, p347
ISSN: 0268-2605
Publication type: Academic Journal
DOI: 10.1002/aoc.3132

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Investigation of fungicidal activity of 3-piperazine-bis(benzoxaborole) and its boronic acid analogue.