Works matching DE "TRIPTERYGIUM wilfordii"

Results: 66

Metabolism: Potential obesity drug from vine.

Published in:: Nature, 2015, v. 521, n. 7553, p. 397, doi. 10.1038/521397d
Publication type:: Article

Chemical Constituents and Cytotoxic Activity of a Fungal Endophyte from Tripterygium wilfordii.

Published in:

Chemistry of Natural Compounds, 2015, v. 51, n. 5, p. 997, doi. 10.1007/s10600-015-1476-4

By:

Yang, Zhong-Duo;
Xue, Peng-Hui;
Shu, Zong-Mei

Publication type:

Article

Secondary Metabolites and Biological Activities of Talaromyces sp. LGT-2, an Endophytic Fungus from Tripterygium Wilfordii.

Published in:

Iranian Journal of Pharmaceutical Research, 2016, v. 15, n. 3, p. 453

By:

Qiu-Hong Zhao;
Zhong-Duo Yang;
Zong-Mei Shu;
Yong-Gang Wang;
Ming-Gang Wang

Publication type:

Article

Protective effect of celastrol on myocardial ischemia-reperfusion injury.

Published in:

Anatolian Journal of Cardiology / Anadolu Kardiyoloji Dergisi, 2017, v. 18, n. 6, p. 384, doi. 10.14744/AnatolJCardiol.2017.7866

By:

Xiaoyan Li;
Nan Wu;
Lu Zou;
Dalin Jia

Publication type:

Article

The Effect of Triptolide in Rheumatoid Arthritis: From Basic Research towards Clinical Translation.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 2, p. 376, doi. 10.3390/ijms19020376

By:

Fan, Danping;
Guo, Qingqing;
Shen, Jiawen;
Zheng, Kang;
Lu, Cheng;
Zhang, Ge;
Lu, Aiping;
He, Xiaojuan

Publication type:

Article

Molecular Cloning and Characterization of DXS and DXR Genes in the Terpenoid Biosynthetic Pathway of Tripterygium wilfordii.

Published in:

International Journal of Molecular Sciences, 2015, v. 16, n. 10, p. 25516, doi. 10.3390/ijms161025516

By:

Yuru Tong;
Ping Su;
Yujun Zhao;
Meng Zhang;
Xiujuan Wang;
Yujia Liu;
Xianan Zhang;
Wei Gao;
Luqi Huang

Publication type:

Article

Celastrol Attenuates Inflammatory and Neuropathic Pain Mediated by Cannabinoid Receptor Type 2.

Published in:

International Journal of Molecular Sciences, 2014, v. 15, n. 8, p. 13637, doi. 10.3390/ijms150813637

By:

Longhe Yang;
Yanting Li;
Jie Ren;
Chenggang Zhu;
Jin Fu;
Donghai Lin;
Yan Qiu

Publication type:

Article

Comparison of tripterygium wilfordii multiglycosides and tacrolimus in the treatment of idiopathic membranous nephropathy: a prospective cohort study.

Published in:

2015

By:

Shanshan Liu;
Xiayu Li;
Heng Li;
Qian Liang;
Jun Chen;
Jianghua Chen;
Liu, Shanshan;
Li, Xiayu;
Li, Heng;
Liang, Qian;
Chen, Jun;
Chen, Jianghua

Publication type:

journal article

Cloning and functional characterization of an isopentenyl diphosphate isomerase gene from Tripterygium wilfordii.

Published in:

Biotechnology & Applied Biochemistry, 2016, v. 63, n. 6, p. 863, doi. 10.1002/bab.1427

By:

Tong, Yuru;
Zhang, Meng;
Su, Ping;
Zhao, Yujun;
Wang, Xiujuan;
Zhang, Xianan;
Gao, Wei;
Huang, Luqi

Publication type:

Article

Celastrol pretreatment as a therapeutic option against cisplatin-induced nephrotoxicity.

Published in:

Toxicology Research, 2019, v. 8, n. 5, p. 723, doi. 10.1039/c9tx00141g

By:

Boran, Tugce;
Gunaydin, Aysenur;
Jannuzzi, Ayse Tarbin;
Ozcagli, Eren;
Alpertunga, Buket

Publication type:

Article

Plasma metabolic profiling analysis of Strychnos nux-vomica Linn. and Tripterygium wilfordii Hook F-induced renal toxicity using metabolomics coupled with UPLC/Q-TOF-MS.

Published in:

Toxicology Research, 2018, v. 7, n. 6, p. 1153, doi. 10.1039/c8tx00115d

By:

Luo, Houmin;
Gu, Caiyun;
Liu, Chuanxin;
Wang, Yuming;
Wang, Hao;
Li, Yubo

Publication type:

Article

A MDR transporter contributes to the different extracellular production of sesquiterpene pyridine alkaloids between adventitious root and hairy root liquid cultures of Tripterygium wilfordii Hook.f.

Published in:

Plant Molecular Biology, 2017, v. 95, n. 1-2, p. 51, doi. 10.1007/s11103-017-0634-4

By:

Miao, Guo-peng;
Han, Juan;
Zhang, Ji-feng;
Zhu, Chuan-shu;
Zhang, Xing

Publication type:

Article

Advances in structural modifications of celastrol.

Published in:

ARKIVOC: Online Journal of Organic Chemistry, 2016, p. 172, doi. 10.3998/ark.5550190.p009.540

By:

Xiao-hua Cai;
Jun Jin;
Meng Huiyuan He

Publication type:

Article

Curative efficacy of vitamin D3 in combination with tripterygium wilfordii polyglycoside in patients with rheumatoid arthritis and its influences on indices of bone restoration.

Published in:

Journal of Hainan Medical University, 2019, v. 25, n. 6, p. 55

By:

Lei Cao;
Hong-Yan Wen

Publication type:

Article

(5R)-5-hydroxytriptolide (LLDT-8) prevents collagen-induced arthritis through OPG/RANK/RANKL signaling in a rat model of rheumatoid arthritis.

Published in:

Experimental & Therapeutic Medicine, 2016, v. 12, n. 5, p. 3101, doi. 10.3892/etm.2016.3739

By:

JI-ZHOU ZENG;
LI-FENG MA;
HAI MENG;
HAO-MIAO YU;
YA-KUI ZHANG;
AI GUO

Publication type:

Article

Tripterygium glycosides induce premature ovarian failure in rats by promoting p53 phosphorylation and activating the serine/threonine kinase 11-p53-p21 signaling pathway.

Published in:

Experimental & Therapeutic Medicine, 2015, v. 10, n. 1, p. 12, doi. 10.3892/etm.2015.2498

By:

TE LIU;
LINA ZHANG;
SUWEI WANG;
CHUAN CHEN;
JIN ZHENG

Publication type:

Article

Triptolide induces apoptosis of breast cancer cells via a mechanism associated with the Wnt/β-catenin signaling pathway.

Published in:

Experimental & Therapeutic Medicine, 2014, v. 8, n. 2, p. 505, doi. 10.3892/etm.2014.1729

By:

HONGMIN SHAO;
JINGHUA MA;
TIANHUA GUO;
RONGRONG HU

Publication type:

Article

Effects of Tripterygium glycosides on interleukin-17 and CD4+CD25+ CD127low regulatory T-cell expression in the peripheral blood of patients with ankylosing spondylitis.

Published in:

Biomedical Reports, 2014, v. 2, n. 4, p. 517, doi. 10.3892/br.2014.262

By:

WEI JI;
HONGGANG LI;
FENG GAO;
YAJUN CHEN;
LINGYU ZHONG;
DAN WANG

Publication type:

Article

Evaluation of anticancer activity of celastrol liposomes in prostate cancer cells.

Published in:

Journal of Microencapsulation, 2014, v. 31, n. 5, p. 501, doi. 10.3109/02652048.2013.879932

By:

Wolfram, Joy;
Suri, Krishna;
Huang, Yi;
Molinaro, Roberto;
Borsoi, Carlotta;
Scott, Bronwyn;
Boom, Kathryn;
Paolino, Donatella;
Fresta, Massimo;
Wang, Jianghua;
Ferrari, Mauro;
Celia, Christian;
Shen, Haifa

Publication type:

Article

Quercetin ameliorates liver injury induced with Tripterygium glycosides by reducing oxidative stress and inflammation.

Published in:

Canadian Journal of Physiology & Pharmacology, 2015, v. 93, n. 6, p. 427, doi. 10.1139/cjpp-2015-0038

By:

Wang, Junming;
Miao, Mingsan;
Zhang, Yueyue;
Liu, Ruixin;
Li, Xaobing;
Cui, Ying;
Qu, Lingbo

Publication type:

Article

The synergistic effect of treatment with triptolide and MK-801 in the rat neuropathic pain model.

Published in:

Molecular Pain, 2017, v. 13, p. 1, doi. 10.1177/1744806917746564

By:

Jian Wang;
Yu Qiao;
Ri-Sheng Yang;
Chun-Kui Zhang;
Huang-Hui Wu;
Jia-Ji Lin;
Ting Zhang;
Tao Chen;
Yun-Qing Li;
Yu-Lin Dong;
Jin-Lian Li

Publication type:

Article

Triptolide: A new star for treating human malignancies.

Published in:

2018

By:

Yan, Ping;
Sun, Xiaotian

Publication type:

journal article

Probing the function of protein farnesyltransferase in Tripterygium wilfordii.

Published in:

Plant Cell Reports, 2019, v. 38, n. 2, p. 211, doi. 10.1007/s00299-018-2363-9

By:

Su, Ping;
Gao, Linhui;
Liu, Shuang;
Guan, Hongyu;
Wang, Jian;
Zhang, Yifeng;
Zhao, Yujun;
Hu, Tianyuan;
Tu, Lichan;
Zhou, Jiawei;
Ma, Baowei;
Liu, Xihong;
Huang, Luqi;
Gao, Wei

Publication type:

Article

Tripterygium wilfordii mitigates hyperglycemia‑induced upregulated Wnt/β-catenin expression and kidney injury in diabetic rats.

Published in:

Experimental & Therapeutic Medicine, 2018, v. 15, n. 4, p. 3874, doi. 10.3892/etm.2018.5901

By:

Chang, Baochao;
Chen, Weidong;
Zhang, Yan;
Yang, Ping;
Liu, Lei

Publication type:

Article

Phylogeographic and phylogenetic analysis for Tripterygium species delimitation.

Published in:

Ecology & Evolution (20457758), 2017, v. 7, n. 20, p. 8612, doi. 10.1002/ece3.3344

By:

Ma, Baowei;
Hu, Tianyuan;
Li, Pei;
Yuan, Qingjun;
Lin, Zhaoshou;
Tu, Yuhe;
Li, Jia;
Zhang, Xianan;
Wu, Xiaoyi;
Wang, Xiujuan;
Huang, Luqi;
Gao, Wei

Publication type:

Article

Neuroprotective effects of DAHP and Triptolide in focal cerebral ischemia via apoptosis inhibition and PI3K/Akt/mTOR pathway activation.

Published in:

Frontiers in Neuroanatomy, 2015, v. 9, p. 1, doi. 10.3389/fnana.2015.00048

By:

Weiyun Li;
Yang Yang;
Zhiying Hu;
Shucai Ling;
Marong Fang

Publication type:

Article

Identification of Genes Involved in the Biosynthesis of Tripterygium wilfordii Hook.f. Secondary Metabolites by Suppression Subtractive Hybridization.

Published in:

Plant Molecular Biology Reporter, 2015, v. 33, n. 4, p. 756, doi. 10.1007/s11105-014-0792-3

By:

Miao, Guo-peng;
Li, Wei;
Zhang, Bin;
Zhang, Zhan-feng;
Ma, Zhi-qing;
Feng, Jun-tao;
Zhang, Xing;
Zhu, Chuan-shu

Publication type:

Article

Effects of Plant Stress Signal Molecules on the Production of Wilforgine in an Endophytic Actinomycete Isolated from Tripterygium wilfordii Hook.f.

Published in:

Current Microbiology, 2015, v. 70, n. 4, p. 571, doi. 10.1007/s00284-014-0758-6

By:

Miao, Guo-peng;
Zhu, Chuan-shu;
Feng, Jun-tao;
Han, Li-rong;
Zhang, Xing

Publication type:

Article

The Comparative Study and Exploration on Mechanism of Tripterygium wilfordii Tablets, Tripterygium wilfordii Polyglycoside and Water Decoction of Tripterygium wilfordii.

Published in:

Medicinal Plant, 2014, v. 5, n. 8, p. 23

By:

FENG, Qun;
SUN, Rong

Publication type:

Article

Covalent Modification of a Cysteine Residue in the XPB Subunit of the General Transcription Factor TFIIH Through Single Epoxide Cleavage of the Transcription Inhibitor Triptolide.

Published in:

Angewandte Chemie International Edition, 2015, v. 54, n. 6, p. 1859, doi. 10.1002/anie.201408817

By:

He, Qing-Li;
Liu, Jun O.;
Titov, Denis V.;
Li, Jing;
Romo, Daniel;
Tan, Minjia;
Zhao, Yingming;
Ye, Zhaohui

Publication type:

Article

Tripchlorolide improves cognitive deficits by reducing amyloid β and upregulating synapse-related proteins in a transgenic model of Alzheimer's Disease.

Published in:

Journal of Neurochemistry, 2015, v. 133, n. 1, p. 38, doi. 10.1111/jnc.13056

By:

Zeng, Yuqi;
Zhang, Jian;
Zhu, Yuangui;
Zhang, Jing;
Shen, Hui;
Lu, Jianping;
Pan, Xiaodong;
Lin, Nan;
Dai, Xiaoman;
Zhou, Meng;
Chen, Xiaochun

Publication type:

Article

Tripchlorolide ameliorates experimental autoimmune encephalomyelitis by down-regulating ERK1/2-NF-κB and JAK/ STAT signaling pathways.

Published in:

Journal of Neurochemistry, 2015, v. 133, n. 1, p. 104, doi. 10.1111/jnc.13058

By:

Zhang, Jian;
Zeng, Yu‐qi;
Zhang, Jing;
Pan, Xiao‐dong;
Kang, De‐yong;
Huang, Tian‐wen;
Chen, Xiao‐chun

Publication type:

Article

Development and application of a comprehensive lipidomic analysis to investigate Tripterygium wilfordii-induced liver injury.

Published in:

Analytical & Bioanalytical Chemistry, 2016, v. 408, n. 16, p. 4341, doi. 10.1007/s00216-016-9533-9

By:

Xie, Tong;
Zhou, Xueping;
Wang, Shouchuan;
Lu, Yan;
Zhu, Huaxu;
Kang, An;
Deng, Haishan;
Xu, Jianya;
Shen, Cunsi;
Di, Liuqing;
Shan, Jinjun

Publication type:

Article

Preparation of high drug-loading celastrol nanosuspensions and their anti-breast cancer activities in vitro and in vivo.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-65773-9

By:

Huang, Tiantian;
Wang, Yian;
Shen, Yiping;
Ao, Hui;
Guo, Yifei;
Han, Meihua;
Wang, Xiangtao

Publication type:

Article

Genetic Transformation System for Woody Plant Tripterygium wilfordii and Its Application to Product Natural Celastrol.

Published in:

Frontiers in Plant Science, 2018, p. 1, doi. 10.3389/fpls.2017.02221

By:

Zhao, Yujun;
Zhang, Yifeng;
Su, Ping;
Yang, Jian;
Huang, Luqi;
Gao, Wei

Publication type:

Article

Licorice root extract and magnesium isoglycyrrhizinate protect against triptolide-induced hepatotoxicity via up-regulation of the Nrf2 pathway.

Published in:

Drug Delivery, 2018, v. 25, n. 1, p. 1213, doi. 10.1080/10717544.2018.1472676

By:

Tan, Qin-You;
Hu, Qian;
Zhu, Sheng-Nan;
Jia, Lu-Lu;
Xiao, Juan;
Su, Hua-Zhen;
Huang, Shao-Yuan;
Zhang, Jing;
Jin, Junfei

Publication type:

Article

Untargeted analysis of sesquiterpene pyridine alkaloids from the dried roots of Tripterygium wilfordii using high-performance liquid chromatography/electrospray ionization tandem mass spectrometry.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2015, v. 29, n. 10, p. 965, doi. 10.1002/rcm.7186

By:

Cai, Tian;
Luo, Ying‐Gang;
Zhou, Min;
Wang, Dan;
Wu, Zhi‐Jun;
Fang, Dong‐Mei;
Zhang, Guo‐Lin

Publication type:

Article

Evaluation of Immunosuppressive Activity of Demethylzeylasteral in a Beagle Dog Kidney Transplantation Model.

Published in:

Cell Biochemistry & Biophysics, 2015, v. 73, n. 3, p. 673, doi. 10.1007/s12013-015-0684-7

By:

An, Huimin;
Zhu, Yu;
Xu, Wenping;
Liu, Yujun;
Zhang, Jianping;
Lin, Zongming

Publication type:

Article

The Antagonistic Effect of Oral Contraceptives on the Tripterygium Wilfordii Polyglycoside-induced Gonad Toxicity: Experimental Study of Female SD Rats.

Published in:

Journal of International Reproductive Health/Family Planning, 2014, v. 33, n. 1, p. 11

By:

GU Jiang-hong;
JIN Ai-hong;
GONG Zhi-yong;
ZHU Zhen;
DU Lan-fang;
LI Ya-qin;
PENG Huang-qing

Publication type:

Article

Probing the Single Key Amino Acid Responsible for the Novel Catalytic Function of ent-Kaurene Oxidase Supported by NADPH-Cytochrome P450 Reductases in Tripterygium wilfordii.

Published in:

Frontiers in Plant Science, 2017, p. 1, doi. 10.3389/fpls.2017.01756

By:

Ping Su;
Hongyu Guan;
Yifeng Zhang;
Xing Wang;
Linhui Gao;
Yujun Zhao;
Tianyuan Hu;
Jiawei Zhou;
Baowei Ma;
Lichan Tu;
Yuru Tong;
Luqi Huang;
Wei Gao

Publication type:

Article

Triptolide inhibits cell proliferation and tumorigenicity of human neuroblastoma cells.

Published in:

Molecular Medicine Reports, 2015, v. 11, n. 2, p. 791, doi. 10.3892/mmr.2014.2814

By:

XIAOMIN YAN;
XIAO-XUE KE;
HAILONG ZHAO;
MENGYING HUANG;
RENJIAN HU;
HONGJUAN CUI

Publication type:

Article

Anti-inflammatory effects of triptolide by inhibiting the NF-κB signalling pathway in LPS-induced acute lung injury in a murine model.

Published in:

Molecular Medicine Reports, 2014, v. 10, n. 1, p. 447, doi. 10.3892/mmr.2014.2191

By:

XIAN WANG;
LEI ZHANG;
WEI DUAN;
BIN LIU;
PING GONG;
YUSONG DING;
XIONGWEN WU

Publication type:

Article

Molecular Cloning and Characterisation of Farnesyl Pyrophosphate Synthase from Tripterygium wilfordii.

Published in:

PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0125415

By:

Zhao, Yu-Jun;
Chen, Xin;
Zhang, Meng;
Su, Ping;
Liu, Yu-Jia;
Tong, Yu-Ru;
Wang, Xiu-Juan;
Huang, Lu-Qi;
Gao, Wei

Publication type:

Article

Activation of Nrf2 Protects against Triptolide-Induced Hepatotoxicity.

Published in:

PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0100685

By:

Li, Jia;
Shen, Feihai;
Guan, Cuiwen;
Wang, Wenwen;
Sun, Xiaozhe;
Fu, Xinlu;
Huang, Min;
Jin, Jing;
Huang, Zhiying

Publication type:

Article

Overexpression and RNA interference of <italic>TwDXR</italic> regulate the accumulation of terpenoid active ingredients in <italic>Tripterygium wilfordii</italic>.

Published in:

Biotechnology Letters, 2018, v. 40, n. 2, p. 419, doi. 10.1007/s10529-017-2484-1

By:

Zhang, Yifeng;
Zhao, Yujun;
Wang, Jiadian;
Hu, Tianyuan;
Tong, Yuru;
Zhou, Jiawei;
Song, Yadi;
Gao, Wei;
Huang, Luqi

Publication type:

Article

Safety Profiles of Tripterygium wilfordii Hook F: A Systematic Review and Meta-Analysis.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00402

By:

Chi Zhang;
Ping-Ping Sun;
Hong-Tao Guo;
Yan Liu;
Jian Li;
Xiao-Juan He;
Ai-Ping Lu;
Chukwujekwu, Jude Chinedu;
Ponnusamy, Baskaran

Publication type:

Article

Celastrol ameliorates ulcerative colitis-related colorectal cancer in mice via suppressing inflammatory responses and epithelial-mesenchymal transition.

Published in:

Frontiers in Pharmacology, 2015, v. 6, p. 1, doi. 10.3389/fphar.2015.00320

By:

Lianjie Lin;
Yan Sun;
Dongxu Wang;
Shihang Zheng;
Jing Zhang;
Changqing Zheng

Publication type:

Article

Study of molecular mechanisms underlying the medicinal plant Tripterygium wilfordii-derived compound celastrol in treating diabetic nephropathy based on network pharmacology and molecular docking.

Published in:

Biocell, 2023, v. 47, n. 8, p. 1853, doi. 10.32604/biocell.2023.029353

By:

FENGMEI QIAN;
PEIYAO REN;
LI ZHAO;
DANNA ZHENG;
WENFANG HE;
JUAN JIN

Publication type:

Article

Systematic understanding the mechanisms of Tripterygium wilfordii on atherosclerosis and pharmacodynamics research in Apo E-/-mice model.

Published in:

Pharmacognosy Magazine, 2018, v. 14, n. 58, p. 624, doi. 10.4103/pm.pm_556_17

By:

Liang, Jingyan;
Chen, Lu;
Pan, Yang;
Qian, Yayun;
Wei, Lifu;
Zhang, Yumeng;
He, Kaiming;
Liu, Yanqing;
Wang, Yingge

Publication type:

Article

Further Study of Influence of Panax notoginseng on Intestinal Absorption Characteristics of Triptolide and Tripterine in Rats with Tripterygium wilfordii.

Published in:

Pharmacognosy Magazine, 2018, v. 14, n. 53, p. 95, doi. 10.4103/pm.pm_67_17

By:

Li, Yiqun;
Zhang, Benyong;
Liu, Mengzhu;
Zhang, Xinlong;
Shi, Donglei;
Guo, Liwei;
Duan, Jinao;
Zhou, Xueping;
Zhu, Huaxu;
Zhang, Qichun

Publication type:

Article