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Title

Titelbild: Squalenyl Hydrogen Sulfate Nanoparticles for Simultaneous Delivery of Tobramycin and an Alkylquinolone Quorum Sensing Inhibitor Enable the Eradication of P. aeruginosa Biofilm Infections (Angew. Chem. 26/2020).

Authors

Ho, Duy‐Khiet; Murgia, Xabier; De Rossi, Chiara; Christmann, Rebekka; Hüfner de Mello Martins, Antonio G.; Koch, Marcus; Andreas, Anastasia; Herrmann, Jennifer; Müller, Rolf; Empting, Martin; Hartmann, Rolf W.; Desmaele, Didier; Loretz, Brigitta; Couvreur, Patrick; Lehr, Claus‐Michael

Abstract

Titelbild: Squalenyl Hydrogen Sulfate Nanoparticles for Simultaneous Delivery of Tobramycin and an Alkylquinolone Quorum Sensing Inhibitor Enable the Eradication of P. aeruginosa Biofilm Infections (Angew. Keywords: biofilms; drug delivery; Pseudomonas aeruginosa; quorum sensing inhibitors; tobramycin EN biofilms drug delivery Pseudomonas aeruginosa quorum sensing inhibitors tobramycin 10285 10285 1 06/17/20 20200622 NES 200622 B Der simultane Transport b von Tobramycin- und Alkylchinolon-Inhibitoren durch ein selbstorganisiertes Nanopartikelsystem basierend auf Squalenylhydrogensulfat (SqNPs) stellt eine optimale therapeutische Maßnahme gegen Biofilminfektionen mit I P. aeruginosa i dar. Biofilms, drug delivery, Pseudomonas aeruginosa, quorum sensing inhibitors, tobramycin.

Subjects

QUORUM sensing; SULFURIC acid; TOBRAMYCIN; NANOPARTICLES; PSEUDOMONAS aeruginosa; MUPIROCIN

Publication

Angewandte Chemie, 2020, Vol 132, Issue 26, p10285

ISSN

0044-8249

Publication type

Academic Journal

DOI

10.1002/ange.202005838

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