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Title

Water‐Soluble Non‐Classical Benzene Mimetics.

Authors

Levterov, Vadym V.; Panasyuk, Yaroslav; Pivnytska, Valentyna O.; Mykhailiuk, Pavel K.

Abstract

A new generation of saturated benzene mimetics, 2‐oxabicyclo[2.1.1]hexanes, was developed. These compounds were designed as analogues of bicyclo[1.1.1]pentane with an improved water solubility. Crystallographic analysis of 2‐oxabicyclo[2.1.1]hexanes revealed that they occupy a novel chemical space, but, at the same time, resemble the motif of meta‐disubstituted benzenes.

Subjects

BENZENE; PENTANE; HEXANE; SOLUBILITY

Publication

Angewandte Chemie, 2020, Vol 132, Issue 18, p7228

ISSN

0044-8249

Publication type

Academic Journal

DOI

10.1002/ange.202000548

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