Carbohydrate Self‐Assembly at Surfaces: STM Imaging of Sucrose Conformation and Ordering on Cu(100).

Abb, Sabine; Tarrat, Nathalie; Cortés, Juan; Andriyevsky, Bohdan; Harnau, Ludger; Schön, J. Christian; Rauschenbach, Stephan; Kern, Klaus

Saccharides are ubiquitous biomolecules, but little is known about their interaction with, and assembly at, surfaces. By combining preparative mass spectrometry with scanning tunneling microscopy, we have been able to address the conformation and self‐assembly of the disaccharide sucrose on a Cu(100) surface with subunit‐level imaging. By employing a multistage modeling approach in combination with the experimental data, we can rationalize the conformation on the surface as well as the interactions between the sucrose molecules, thereby yielding models of the observed self‐assembled patterns on the surface.

BIOMOLECULES; MASS spectrometry; MOLECULAR self-assembly; COPPER surfaces; DISACCHARIDES; CARBOHYDRATES; SCANNING tunneling microscopy

Angewandte Chemie, 2019, Vol 131, Issue 25, p8424

0044-8249

Academic Journal

10.1002/ange.201901340