Works matching AU Mykhailiuk, Pavel K.

Results: 92

3‐Oxabicyclo[3.1.1]heptane as an Isostere of meta‐Benzene.

Published in:

Angewandte Chemie International Edition, 2025, v. 64, n. 25, p. 1, doi. 10.1002/anie.202505519

By:

Dibchak, Dmitry;
Mykhailiuk, Pavel K.

Publication type:

Article

3‐Oxabicyclo[3.1.1]heptane as an Isostere of meta‐Benzene.

Published in:

Angewandte Chemie, 2025, v. 137, n. 25, p. 1, doi. 10.1002/ange.202505519

By:

Dibchak, Dmitry;
Mykhailiuk, Pavel K.

Publication type:

Article

Diazoacetonitrile (N2CHCN): A Long Forgotten but Valuable Reagent for Organic Synthesis.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 1, p. 89, doi. 10.1002/chem.201903335

By:

Mykhailiuk, Pavel K.;
Koenigs, Rene M.

Publication type:

Article

Frontispiece: Diazoacetonitrile (N2CHCN): A Long Forgotten but Valuable Reagent for Organic Synthesis.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 1, p. 1, doi. 10.1002/chem.201903335

By:

Mykhailiuk, Pavel K.;
Koenigs, Rene M.

Publication type:

Article

Frontispiece: Diazoacetonitrile (N2CHCN): A Long Forgotten but Valuable Reagent for Organic Synthesis.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1002/chem.201903335

By:

Mykhailiuk, Pavel K.;
Koenigs, Rene M.

Publication type:

Article

In Situ Generation of Difluoromethyl Diazomethane for [3+2] Cycloadditions with Alkynes.

Published in:

Angewandte Chemie, 2015, v. 127, n. 22, p. 6658, doi. 10.1002/ange.201501529

By:

Mykhailiuk, Pavel K.

Publication type:

Article

Titelbild: In Situ Generation of Difluoromethyl Diazomethane for [3+2] Cycloadditions with Alkynes (Angew. Chem. 22/2015).

Published in:

Angewandte Chemie, 2015, v. 127, n. 22, p. 6471, doi. 10.1002/ange.201503577

By:

Mykhailiuk, Pavel K.

Publication type:

Article

Innenrücktitelbild: Controlling Biological Activity with Light: Diarylethene-Containing Cyclic Peptidomimetics (Angew. Chem. 13/2014).

Published in:

Angewandte Chemie, 2014, v. 126, n. 13, p. 3589, doi. 10.1002/ange.201401081

By:

Babii, Oleg;
Afonin, Sergii;
Berditsch, Marina;
Reiβer, Sabine;
Mykhailiuk, Pavel K.;
Kubyshkin, Vladimir S.;
Steinbrecher, Thomas;
Ulrich, Anne S.;
Komarov, Igor V.

Publication type:

Article

Controlling Biological Activity with Light: Diarylethene-Containing Cyclic Peptidomimetics.

Published in:

Angewandte Chemie, 2014, v. 126, n. 13, p. 3460, doi. 10.1002/ange.201310019

By:

Babii, Oleg;
Afonin, Sergii;
Berditsch, Marina;
Reiβer, Sabine;
Mykhailiuk, Pavel K.;
Kubyshkin, Vladimir S.;
Steinbrecher, Thomas;
Ulrich, Anne S.;
Komarov, Igor V.

Publication type:

Article

Design, Synthesis, and Application of a Trifluoromethylated Phenylalanine Analogue as a Label to Study Peptides by Solid-State 19F NMR Spectroscopy.

Published in:

Angewandte Chemie, 2013, v. 125, n. 25, p. 6632, doi. 10.1002/ange.201301344

By:

Tkachenko, Anton N.;
Radchenko, Dmytro S.;
Mykhailiuk, Pavel K.;
Afonin, Sergii;
Ulrich, Anne S.;
Komarov, Igor V.

Publication type:

Article

A 19F NMR Label to Substitute Polar Amino Acids in Peptides: A CF3-Substituted Analogue of Serine and Threonine.

Published in:

Angewandte Chemie, 2013, v. 125, n. 5, p. 1526, doi. 10.1002/ange.201208069

By:

Tkachenko, Anton N.;
Mykhailiuk, Pavel K.;
Afonin, Sergii;
Radchenko, Dmytro S.;
Kubyshkin, Vladimir S.;
Ulrich, Anne S.;
Komarov, Igor V.

Publication type:

Article

One‐Pot Synthesis of 6‐Aminopyrido[2,3‐d]pyrimidin‐7‐ones.

Published in:

European Journal of Organic Chemistry, 2018, v. 2018, n. 46, p. 6519, doi. 10.1002/ejoc.201801204

By:

Zinchenko, Anna M.;
Muzychka, Lyubov V.;
Kucher, Olexandr V.;
Sadkova, Iryna V.;
Mykhailiuk, Pavel K.;
Smolii, Oleg B.

Publication type:

Article

Synthesis of Bi- and Polyfunctional Isoxazoles from Amino Acid Derived Halogenoximes and Active Methylene Nitriles.

Published in:

European Journal of Organic Chemistry, 2018, v. 2018, n. 22, p. 2753, doi. 10.1002/ejoc.201800311

By:

Chalyk, Bohdan A.;
Hrebeniuk, Kateryna V.;
Gavrilenko, Konstantin S.;
Shablykin, Oleh V.;
Yanshyna, Oksana O.;
Bash, Daniil;
Mykhailiuk, Pavel K.;
Liashuk, Oleksandr S.;
Grygorenko, Oleksandr O.

Publication type:

Article

Synthesis of N-Nitroso CHF2-Pyrazolines and Their Transformation into CHF2-Isoxazolines and -Pyrazoles.

Published in:

European Journal of Organic Chemistry, 2017, v. 2017, n. 41, p. 6114, doi. 10.1002/ejoc.201700803

By:

Lebed, Pavlo S.;
Fenneteau, Johan;
Wu, Yong;
Cossy, Janine;
Mykhailiuk, Pavel K.

Publication type:

Article

Synthesis of 6-Azaspiro[4.3]alkanes: Innovative Scaffolds for Drug Discovery.

Published in:

European Journal of Organic Chemistry, 2017, v. 2017, n. 31, p. 4530, doi. 10.1002/ejoc.201700536

By:

Chalyk, Bohdan A.;
Isakov, Andrei A.;
Butko, Maryna V.;
Hrebeniuk, Kateryna V.;
Savych, Olena V.;
Kucher, Olexandr V.;
Gavrilenko, Konstantin S.;
Druzhenko, Tetiana V.;
Yarmolchuk, Vladimir S.;
Zozulya, Sergey;
Mykhailiuk, Pavel K.

Publication type:

Article

Difluoromethyl Nitrile Oxide (CF2HCNO): A Neglected Chemical Reagent.

Published in:

European Journal of Organic Chemistry, 2017, v. 2017, n. 27, p. 3935, doi. 10.1002/ejoc.201700764

By:

Khutorianskyi, Andrii;
Chalyk, Bohdan;
Borysko, Petro;
Kondratiuk, Anna;
Mykhailiuk, Pavel K.

Publication type:

Article

Synthesis of CF2H-Substituted Pyrazolines by [3+2] Cycloaddition between CF2HCHN2 and Electron-Deficient Alkenes.

Published in:

European Journal of Organic Chemistry, 2017, v. 2017, n. 2, p. 266, doi. 10.1002/ejoc.201601462

By:

Li, Jue;
Yu, Xin‐Ling;
Cossy, Janine;
Lv, Song‐Yang;
Zhang, Hai‐Long;
Su, Fu;
Mykhailiuk, Pavel K.;
Wu, Yong

Publication type:

Article

Synthesis of Fluoroalkyl Pyrazoles from In-Situ-Generated C2F5CHN2 and Electron-Deficient Alkenes.

Published in:

European Journal of Organic Chemistry, 2016, v. 2016, n. 33, p. 5485, doi. 10.1002/ejoc.201600947

By:

Mykhailiuk, Pavel K.;
Ishchenko, Aleksandr Yu.;
Stepanenko, Viatcheslav;
Cossy, Janine

Publication type:

Article

Front Cover: Synthesis of Fluoroalkyl Pyrazoles from In-Situ-Generated C2F5CHN2 and Electron-Deficient Alkenes (Eur. J. Org. Chem. 33/2016).

Published in:

European Journal of Organic Chemistry, 2016, v. 2016, n. 33, p. 5445, doi. 10.1002/ejoc.201670331

By:

Mykhailiuk, Pavel K.;
Ishchenko, Aleksandr Yu.;
Stepanenko, Viatcheslav;
Cossy, Janine

Publication type:

Article

2,2,2-Trifluoroethyl Oxalates in the One-Pot Parallel Synthesis of Hindered Aliphatic Oxamides.

Published in:

European Journal of Organic Chemistry, 2016, v. 2016, n. 12, p. 2120, doi. 10.1002/ejoc.201501579

By:

Bogolubsky, Andrey V.;
Moroz, Yurii S.;
Mykhailiuk, Pavel K.;
Pipko, Sergey E.;
Grishchenko, Alexander V.;
Zhemera, Anton V.;
Konovets, Anzhelika I.;
Doroschuk, Roman A.;
Dmytriv, Yurii V.;
Zaporozhets, Olga A.;
Tolmachev, Andrey

Publication type:

Article

2,2,2-Trifluoroethyl Oxalates in the One-Pot Parallel Synthesis of Hindered Aliphatic Oxamides (Eur. J. Org. Chem. 12/2016).

Published in:

European Journal of Organic Chemistry, 2016, v. 2016, n. 12, p. n/a, doi. 10.1002/ejoc.201690022

By:

Bogolubsky, Andrey V.;
Moroz, Yurii S.;
Mykhailiuk, Pavel K.;
Pipko, Sergey E.;
Grishchenko, Alexander V.;
Zhemera, Anton V.;
Konovets, Anzhelika I.;
Doroschuk, Roman A.;
Dmytriv, Yurii V.;
Zaporozhets, Olga A.;
Tolmachev, Andrey

Publication type:

Article

New Life for Diazoacetonitrile (N2CHCN): in situ Generation and Practical Synthesis of CN-Pyrazoles (Eur. J. Org. Chem. 33/2015).

Published in:

European Journal of Organic Chemistry, 2015, v. 2015, n. 33, p. n/a, doi. 10.1002/ejoc.201501027

By:

Mykhailiuk, Pavel K.

Publication type:

Article

New Life for Diazoacetonitrile (N2CHCN): in situ Generation and Practical Synthesis of CN-Pyrazoles.

Published in:

European Journal of Organic Chemistry, 2015, v. 2015, n. 33, p. 7235, doi. 10.1002/ejoc.201501027

By:

Mykhailiuk, Pavel K.

Publication type:

Article

Multigram Synthesis of Fluoroalkyl-Substituted Pyrazole-4-carboxylic Acids.

Published in:

European Journal of Organic Chemistry, 2015, v. 2015, n. 4, p. 886, doi. 10.1002/ejoc.201403295

By:

Iminov, Rustam T.;
Mashkov, Alexander V.;
Vyzir, Ivan I.;
Chalyk, Bohdan A.;
Tverdokhlebov, Anton V.;
Mykhailiuk, Pavel K.;
Babichenko, Ludmila N.;
Tolmachev, Andrey A.;
Volovenko, Yulian M.;
Biitseva, Angelina;
Shishkin, Oleg V.;
Shishkina, Svetlana V.

Publication type:

Article

Enzyme-Catalyzed Kinetic Resolution of 2,2,2-Trifluoro-1-(heteroaryl)ethanols: Experimental and Docking Studies.

Published in:

European Journal of Organic Chemistry, 2014, v. 2014, n. 34, p. 7692, doi. 10.1002/ejoc.201403013

By:

Kucher, Olexandr V.;
Kolodiazhnaya, Anastasiya O.;
Smolii, Oleg B.;
Prisuazhnyk, Dmytro V.;
Tolmacheva, Katerina A.;
Zaporozhets, Olga A.;
Moroz, Yurii S.;
Mykhailiuk, Pavel K.;
Tolmachev, Andrey A.

Publication type:

Article

Design and Synthesis of a Monofluoro-Substituted Aromatic Amino Acid as a Conformationally Restricted 19F NMR Label for Membrane-Bound Peptides.

Published in:

European Journal of Organic Chemistry, 2014, v. 2014, n. 17, p. 3584, doi. 10.1002/ejoc.201301737

By:

Tkachenko, Anton N.;
Mykhailiuk, Pavel K.;
Radchenko, Dmytro S.;
Babii, Oleg;
Afonin, Sergii;
Ulrich, Anne S.;
Komarov, Igor V.

Publication type:

Article

Synthesis of Trifluoromethyl-Substituted 3-Azabicyclo[ n.1.0]alkanes: Advanced Building Blocks for Drug Discovery.

Published in:

European Journal of Organic Chemistry, 2014, v. 2014, n. 17, p. 3592, doi. 10.1002/ejoc.201402158

By:

Artamonov, Olexiy S.;
Slobodyanyuk, Evgeniy Y.;
Volochnyuk, Dmitriy M.;
Komarov, Igor V.;
Tolmachev, Andrey A.;
Mykhailiuk, Pavel K.

Publication type:

Article

One-Pot Synthesis of CF3-Substituted Pyrazolines/Pyrazoles from Electron-Deficient Alkenes/Alkynes and CF3CHN2 Generated in situ: Optimized Synthesis of Tris(trifluoromethyl)pyrazole.

Published in:

European Journal of Organic Chemistry, 2014, v. 2014, n. 12, p. 2487, doi. 10.1002/ejoc.201301852

By:

Slobodyanyuk, Evgeniy Y.;
Artamonov, Olexiy S.;
Shishkin, Oleg V.;
Mykhailiuk, Pavel K.

Publication type:

Article

Synthesis and Characterization of β-Trifluoromethyl-Substituted Pyrrolidines.

Published in:

European Journal of Organic Chemistry, 2013, v. 2013, n. 15, p. 3086, doi. 10.1002/ejoc.201300121

By:

Yarmolchuk, Vladimir S.;
Shishkin, Oleg V.;
Starova, Viktoriia S.;
Zaporozhets, Olga A.;
Kravchuk, Olga;
Zozulya, Sergey;
Komarov, Igor V.;
Mykhailiuk, Pavel K.

Publication type:

Article

A Convenient Route to 1-Alkyl-5-trifluoromethyl-1,2,3-triazole-4-carboxylic Acids Employing a Diazo Transfer Reaction.

Published in:

European Journal of Organic Chemistry, 2013, v. 2013, n. 14, p. 2891, doi. 10.1002/ejoc.201300030

By:

Iminov, Rustam T.;
Mashkov, Alexander V.;
Chalyk, Bohdan A.;
Mykhailiuk, Pavel K.;
Tverdokhlebov, Anton V.;
Tolmachev, Andrey A.;
Volovenko, Yulian M.;
Shishkin, Oleg V.;
Shishkina, Svetlana V.

Publication type:

Article

Synthesis of Trifluoromethyl-Substituted Proline Analogues as.

Published in:

Angewandte Chemie International Edition, 2008, v. 47, n. 31, p. 5765, doi. 10.1002/anie.200801022

By:

Mykhailiuk, Pavel K.;
Afonin, Sergii;
Palamarchuk, Gennady V.;
Shishkin, Oleg V.;
Ulrich, Anne S.;
Komarov, Igor V.

Publication type:

Article

Frontispiece: Difluorodiazoethane (CF2HCHN2): A New Reagent for the Introduction of the Difluoromethyl Group.

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 24, p. N.PAG, doi. 10.1002/chem.201982461

By:

Mykhailiuk, Pavel K.;
Koenigs, Rene M.

Publication type:

Article

Difluorodiazoethane (CF2HCHN2): A New Reagent for the Introduction of the Difluoromethyl Group.

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 24, p. 6053, doi. 10.1002/chem.201804953

By:

Mykhailiuk, Pavel K.;
Koenigs, Rene M.

Publication type:

Article

Cover Feature: Synthesis of Functionalized Difluorocyclopropanes: Unique Building Blocks for Drug Discovery (Chem. Eur. J. 47/2018).

Published in:

2018

By:

Bychek, Roman M.;
Levterov, Vadym V.;
Sadkova, Iryna V.;
Tolmachev, Andrey A.;
Mykhailiuk, Pavel K.

Publication type:

Cover Art

Synthesis of Functionalized Difluorocyclopropanes: Unique Building Blocks for Drug Discovery.

Published in:

Chemistry - A European Journal, 2018, v. 24, n. 47, p. 12291, doi. 10.1002/chem.201705708

By:

Bychek, Roman M.;
Levterov, Vadym V.;
Sadkova, Iryna V.;
Tolmachev, Andrey A.;
Mykhailiuk, Pavel K.

Publication type:

Article

Cover Feature: Saturated Heterocyclic Aminosulfonyl Fluorides: New Scaffolds for Protecting‐Group‐Free Synthesis of Sulfonamides (Chem. Eur. J. 33/2018).

Published in:

Chemistry - A European Journal, 2018, v. 24, n. 33, p. 8243, doi. 10.1002/chem.201802690

By:

Zhersh, Sergey A.;
Blahun, Oleksandr P.;
Sadkova, Iryna V.;
Tolmachev, Andrey A.;
Moroz, Yurii S.;
Mykhailiuk, Pavel K.

Publication type:

Article

Saturated Heterocyclic Aminosulfonyl Fluorides: New Scaffolds for Protecting‐Group‐Free Synthesis of Sulfonamides.

Published in:

Chemistry - A European Journal, 2018, v. 24, n. 33, p. 8343, doi. 10.1002/chem.201801140

By:

Zhersh, Sergey A.;
Blahun, Oleksandr P.;
Sadkova, Iryna V.;
Tolmachev, Andrey A.;
Moroz, Yurii S.;
Mykhailiuk, Pavel K.

Publication type:

Article

Cover Feature: Synthesis of Multifunctional Spirocyclic Azetidines and Their Application in Drug Discovery (Chem. Eur. J. 21/2018).

Published in:

Chemistry - A European Journal, 2018, v. 24, n. 21, p. 5398, doi. 10.1002/chem.201800624

By:

Kirichok, Alexander A.;
Shton, Irina O.;
Pishel, Irina M.;
Zozulya, Sergey A.;
Borysko, Petro O.;
Kubyshkin, Vladimir;
Zaporozhets, Olha A.;
Tolmachev, Andrei A.;
Mykhailiuk, Pavel K.

Publication type:

Article

Synthesis of Multifunctional Spirocyclic Azetidines and Their Application in Drug Discovery.

Published in:

Chemistry - A European Journal, 2018, v. 24, n. 21, p. 5444, doi. 10.1002/chem.201800193

By:

Kirichok, Alexander A.;
Shton, Irina O.;
Pishel, Irina M.;
Zozulya, Sergey A.;
Borysko, Petro O.;
Kubyshkin, Vladimir;
Zaporozhets, Olha A.;
Tolmachev, Andrei A.;
Mykhailiuk, Pavel K.

Publication type:

Article

Synthesis of Spirocyclic Pyrrolidines: Advanced Building Blocks for Drug Discovery.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 66, p. 16695, doi. 10.1002/chem.201704330

By:

Chalyk, Bohdan A.;
Butko, Maryna V.;
Yanshyna, Oksana O.;
Gavrilenko, Konstantin S.;
Druzhenko, Tetiana V.;
Mykhailiuk, Pavel K.

Publication type:

Article

Front Cover: Synthesis of Spirocyclic Pyrrolidines: Advanced Building Blocks for Drug Discovery (Chem. Eur. J. 66/2017).

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 66, p. 16691, doi. 10.1002/chem.201704329

By:

Chalyk, Bohdan A.;
Butko, Maryna V.;
Yanshyna, Oksana O.;
Gavrilenko, Konstantin S.;
Druzhenko, Tetiana V.;
Mykhailiuk, Pavel K.

Publication type:

Article

Synthesis of Spirocyclic Pyrrolidines: Advanced Building Blocks for Drug Discovery.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 66, p. 16782, doi. 10.1002/chem.201702362

By:

Chalyk, Bohdan A.;
Butko, Maryna V.;
Yanshyna, Oksana O.;
Gavrilenko, Konstantin S.;
Druzhenko, Tetiana V.;
Mykhailiuk, Pavel K.

Publication type:

Article

Frontispiece: Selective 19F-Labeling of Functionalized Carboxylic Acids with Difluoromethyl Diazomethane (CF2HCHN2).

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 54, p. n/a, doi. 10.1002/chem.201703446

By:

Mykhailiuk, Pavel K.;
Kishko, Igor;
Kubyshkin, Vladimir;
Budisa, Nediljko;
Cossy, Janine

Publication type:

Article

Selective 19F-Labeling of Functionalized Carboxylic Acids with Difluoromethyl Diazomethane (CF2HCHN2).

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 54, p. 13279, doi. 10.1002/chem.201703446

By:

Mykhailiuk, Pavel K.;
Kishko, Igor;
Kubyshkin, Vladimir;
Budisa, Nediljko;
Cossy, Janine

Publication type:

Article

Structure Analysis and Conformational Transitions of the Cell Penetrating Peptide Transportan 10 in the Membrane-Bound State.

Published in:

PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0099653

By:

Fanghänel, Susanne;
Wadhwani, Parvesh;
Strandberg, Erik;
Verdurmen, Wouter P. R.;
Bürck, Jochen;
Ehni, Sebastian;
Mykhailiuk, Pavel K.;
Afonin, Sergii;
Gerthsen, Dagmar;
Komarov, Igor V.;
Brock, Roland;
Ulrich, Anne S.

Publication type:

Article

Front Cover: Synthesis of 2,2‐Disubstituted Spirocyclic Pyrrolidines by Intramolecular Dieckmann Condensation (Eur. J. Org. Chem. 22/2019).

Published in:

European Journal of Organic Chemistry, 2019, v. 2019, n. 22, p. 3542, doi. 10.1002/ejoc.201900755

By:

Fominova, Kateryna;
Diachuk, Taras;
Sadkova, Iryna V.;
Mykhailiuk, Pavel K.

Publication type:

Article

Synthesis of 2,2‐Disubstituted Spirocyclic Pyrrolidines by Intramolecular Dieckmann Condensation.

Published in:

European Journal of Organic Chemistry, 2019, v. 2019, n. 22, p. 3553, doi. 10.1002/ejoc.201801750

By:

Fominova, Kateryna;
Diachuk, Taras;
Sadkova, Iryna V.;
Mykhailiuk, Pavel K.

Publication type:

Article

Generation of C2F5CHN2 In Situ and Its First Reaction: [3+2] Cycloaddition with Alkenes.

Published in:

Chemistry - A European Journal, 2014, v. 20, n. 17, p. 4942, doi. 10.1002/chem.201304840

By:

Mykhailiuk , Pavel K.

Publication type:

Article

Back Cover: Generation of C2F5CHN2 In Situ and Its First Reaction: [3+2] Cycloaddition with Alkenes (Chem. Eur. J. 17/2014).

Published in:

Chemistry - A European Journal, 2014, v. 20, n. 17, p. 5168, doi. 10.1002/chem.201490070

By:

Mykhailiuk , Pavel K.

Publication type:

Article

(5 S)-5-(Trifluoromethyl)pyrrolidin-2-one as a Promising Building Block for Fluoroorganic Chemistry.

Published in:

European Journal of Organic Chemistry, 2011, v. 2011, n. 9, p. 1782, doi. 10.1002/ejoc.201001362

By:

Bezdudny, Andrii V.;
Alekseenko, Anatoliy N.;
Mykhailiuk, Pavel K.;
Manoilenko, Olga V.;
Shishkin, Oleg V.;
Pustovit, Yurii M.

Publication type:

Article