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Novel Functional, Health, and Genetic Determinants of Cognitive Terminal Decline: Kuakini Honolulu Heart Program/Honolulu-Asia Aging Study.
Published in:
2022
By:
- Margrett, Jennifer A;
- Schofield, Thomas;
- Martin, Peter;
- Poon, Leonard W;
- Masaki, Kamal;
- Donlon, Timothy A;
- Kallianpur, Kalpana J;
- Willcox, Bradley J
Publication type:
journal article
FOXO3, a Resilience Gene: Impact on Lifespan, Healthspan, and Deathspan.
Published in:
2022
By:
- Donlon, Timothy A;
- Morris, Brian J;
- Masaki, Kamal H;
- Chen, Randi;
- Davy, Phillip M C;
- Kallianpur, Kalpana J;
- Nakagawa, Kazuma;
- Owens, Jesse B;
- Willcox, D Craig;
- Allsopp, Richard C;
- Willcox, Bradley J
Publication type:
journal article
Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity.
Published in:
2018
By:
- Donlon, Timothy A;
- Morris, Brian J;
- Chen, Randi;
- Masaki, Kamal H;
- Allsopp, Richard C;
- Willcox, D Craig;
- Tiirikainen, Maarit;
- Willcox, Bradley J
Publication type:
journal article
Minimal Shortening of Leukocyte Telomere Length Across Age Groups in a Cross-Sectional Study for Carriers of a Longevity-Associated FOXO3 Allele.
Published in:
2018
By:
- Davy, Philip M C;
- Willcox, D Craig;
- Shimabukuro, Michio;
- Donlon, Timothy A;
- Torigoe, Trevor;
- Suzuki, Makoto;
- Higa, Moritake;
- Masuzaki, Hiroaki;
- Sata, Masataka;
- Chen, Randi;
- Murkofsky, Rachel L;
- Morris, Brian J;
- Lim, Eunjung;
- Allsopp, Richard C;
- Willcox, Bradley J
Publication type:
journal article
Association of Polymorphisms in Connective Tissue Growth Factor and Epidermal Growth Factor Receptor Genes With Human Longevity.
Published in:
2017
By:
- Donlon, Timothy A.;
- Morris, Brian J.;
- Qimei He;
- Randi Chen;
- Masaki, Kamal H.;
- Allsopp, Richard C.;
- Willcox, Craig;
- Tranah, Gregory J.;
- Parimi, Neeta;
- Evans, Daniel S.;
- Flachsbart, Friederike;
- Nebel, Almut;
- Duk-Hwan Kim;
- Joobae Park;
- Willcox, Bradley J.;
- He, Qimei;
- Chen, Randi;
- Willcox, D Craig;
- Kim, Duk-Hwan;
- Park, Joobae
Publication type:
journal article
Longevity-Associated FOXO3 Genotype and its Impact on Coronary Artery Disease Mortality in Japanese, Whites, and Blacks: A Prospective Study of Three American Populations.
Published in:
2017
By:
- Willcox, Bradley J.;
- Morris, Brian J.;
- Tranah, Gregory J.;
- Randi Chen;
- Masaki, Kamal H.;
- Qimei He;
- Willcox, D. Craig;
- Allsopp, Richard C.;
- Moisyadi, Stefan;
- Gerschenson, Mariana;
- Davy, Philip M. C.;
- Poon, Leonard W.;
- Rodriguez, Beatriz;
- Newman, Anne B.;
- Harris, Tamara B.;
- Cummings, Steven R.;
- Yongmei Liu;
- Parimi, Neeta;
- Evans, Daniel S.;
- Donlon, Timothy A.
Publication type:
journal article
Genetic analysis of TOR complex gene variation with human longevity: a nested case-control study of American men of Japanese ancestry.
Published in:
2015
By:
- Morris, Brian J;
- Donlon, Timothy A;
- He, Qimei;
- Grove, John S;
- Masaki, Kamal H;
- Elliott, Ayako;
- Willcox, D Craig;
- Allsopp, Richard;
- Willcox, Bradley J
Publication type:
journal article
Genetic Analysis of TOR Complex Gene Variation With Human Longevity: A Nested Case–Control Study of American Men of Japanese Ancestry.
Published in:
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2015, v. 70, n. 2, p. 133, doi. 10.1093/gerona/glu021
By:
- Morris, Brian J.;
- Donlon, Timothy A.;
- He, Qimei;
- Grove, John S.;
- Masaki, Kamal H.;
- Elliott, Ayako;
- Willcox, D. Craig;
- Allsopp, Richard;
- Willcox, Bradley J.
Publication type:
Article
Who Are the Okinawans? Ancestry, Genome Diversity, and Implications for the Genetic Study of Human Longevity From a Geographically Isolated Population.
Published in:
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2014, v. 69, n. 12, p. 1474, doi. 10.1093/gerona/glt203
By:
- Bendjilali, Nasrine;
- Hsueh, Wen-Chi;
- He, Qimei;
- Willcox, D. Craig;
- Nievergelt, Caroline M.;
- Donlon, Timothy A.;
- Kwok, Pui-Yan;
- Suzuki, Makoto;
- Willcox, Bradley J.
Publication type:
Article
Association Analyses of Insulin Signaling Pathway Gene Polymorphisms With Healthy Aging and Longevity in Americans of Japanese Ancestry.
Published in:
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2014, v. 69A, n. 3, p. 270, doi. 10.1093/gerona/glt082
By:
- Morris, Brian J.;
- Donlon, Timothy A.;
- He, Qimei;
- Grove, John S.;
- Masaki, Kamal H.;
- Elliott, Ayako;
- Willcox, D. Craig;
- Willcox, Bradley J.
Publication type:
Article
FOXO3 Gene Variants and Human Aging: Coding Variants May Not Be Key Players.
Published in:
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2012, v. 67, n. 11, p. 1132, doi. 10.1093/gerona/gls067
By:
- Donlon, Timothy A.;
- Curb, J. David;
- He, Qimei;
- Grove, John S.;
- Masaki, Kamal H.;
- Rodriguez, Beatriz;
- Elliott, Ayako;
- Willcox, D. Craig;
- Willcox, Bradley J.
Publication type:
Article
A Prospective Study of High-Density Lipoprotein Cholesterol, Cholesteryl Ester Transfer Protein Gene Variants, and Healthy Aging in Very Old Japanese-American Men.
Published in:
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2008, v. 63, n. 11, p. 1235, doi. 10.1093/gerona/63.11.1235
By:
- Koropatnick, Tanya A.;
- Kimbell, Jennifer;
- Chen, Randi;
- Grove, John S.;
- Donlon, Timothy A.;
- Masaki, Kamal H.;
- Rodriguez, Beatriz L.;
- Wilcox, Bradley J.;
- Yano, Katsuhiko;
- Curb, J. David
Publication type:
Article
Genes That Extend Lifespan May Do So by Mitigating the Increased Risk of Death Posed by Having Hypertension.
Published in:
American Journal of Hypertension, 2023, v. 36, n. 12, p. 631, doi. 10.1093/ajh/hpad070
By:
- Morris, Brian J;
- Donlon, Timothy A
Publication type:
Article
Association with Longevity of Phosphatidylinositol 3-Kinase Regulatory Subunit 1 Gene Variants Stems from Protection against Mortality Risk in Men with Cardiovascular Disease.
Published in:
Gerontology, 2022, v. 68, n. 2, p. 162, doi. 10.1159/000515390
By:
- Donlon, Timothy A.;
- Chen, Randi;
- Masaki, Kamal H.;
- Willcox, Bradley J.;
- Morris, Brian J.
Publication type:
Article
FOXO3: A Major Gene for Human Longevity--A Mini-Review.
Published in:
2015
By:
- Morris, Brian J.;
- Willcox, Donald Craig;
- Donlon, Timothy a.;
- Willcox, Bradley J.
Publication type:
journal article
Association of the Cyclin D1 A870G Polymorphism With Advanced Colorectal Cancer.
Published in:
JAMA: Journal of the American Medical Association, 2003, v. 290, n. 21, p. 2843, doi. 10.1001/jama.290.21.2843
By:
- Marchand, Loïc Le;
- Seifried, Ann;
- Lum-Jones, Annette;
- Donlon, Timothy;
- Wilkens, Lynne R.
Publication type:
Article
Azoospermia Secondary to a Novel X-Autosomal Reciprocal Translocation: 46,Y, t(X:16)(p22.1:p11.2).
Published in:
2020
By:
- Choi, Lindsey;
- Levy, Gary;
- Donlon, Timothy;
- Sterbis, Joseph;
- Pier, Bruce
Publication type:
journal article
Does FOXO3 longevity genotype explain the conflicting data on late‐life hypertension and risk of Alzheimer's disease?
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082406
By:
- Chen, Randi;
- Morris, Brian J;
- Donlon, Timothy A;
- Ross, G. Webster;
- Kallianpur, Kalpana J;
- Willcox, Bradley J;
- Allsopp, Richard C;
- Nakagawa, Kazuma;
- Masaki, Kamal H
Publication type:
Article
FOXO3 longevity genotype protects elderly men with late‐life hypertension from Alzheimer's disease – Kuakini Honolulu Heart Program.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 11, p. 1, doi. 10.1002/alz.059903
By:
- Chen, Randi;
- Morris, Brian J;
- Donlon, Timothy A;
- Ross, G Webster;
- Willcox, Bradley J;
- Allsopp, Richard C;
- Nakagawa, Kazuma;
- Masaki, Kamal H
Publication type:
Article
Treatment of myelodysplastic syndromes with recombinant human granulocyte colony-stimulating factor. A phase I-II trial.
Published in:
1989
By:
- Negrin, Robert S.;
- Haeuber, Douglas H.;
- Nagler, Arnon;
- Olds, Lynne C.;
- Donlon, Timothy;
- Souza, Lawrence M.;
- Greenberg, Peter L.;
- Negrin, R S;
- Haeuber, D H;
- Nagler, A;
- Olds, L C;
- Donlon, T;
- Souza, L M;
- Greenberg, P L
Publication type:
journal article
In silico analysis of human renin gene–gene interactions and neighborhood topologically associated domains suggests breakdown of insulators contribute to ageing-associated diseases.
Published in:
Biogerontology, 2019, v. 20, n. 6, p. 857, doi. 10.1007/s10522-019-09834-1
By:
- Donlon, Timothy A.;
- Morris, Brian J.
Publication type:
Article
Shorter Men Live Longer: Association of Height with Longevity and <i>FOXO3</i> Genotype in American Men of Japanese Ancestry.
Published in:
PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0094385
By:
- He, Qimei;
- Morris, Brian J.;
- Grove, John S.;
- Petrovitch, Helen;
- Ross, Webster;
- Masaki, Kamal H.;
- Rodriguez, Beatriz;
- Chen, Randi;
- Donlon, Timothy A.;
- Willcox, D. Craig;
- Willcox, Bradley J.
Publication type:
Article
Common ALDH2 genetic variants predict development of hypertension in the SAPPHIRe prospective cohort: Gene-environmental interaction with alcohol consumption.
Published in:
BMC Cardiovascular Disorders, 2012, v. 12, n. 1, p. 58, doi. 10.1186/1471-2261-12-58
By:
- Yi-Cheng Chang;
- Yen-Feng Chiu;
- I-Te Lee;
- Low-Tone Ho;
- Yi-Jen Hung;
- Chao A Hsiung;
- Quertermous, Thomas;
- Donlon, Timothy;
- Wei-Jei Lee;
- Po-Chu Lee;
- Che-Hong Chen;
- Mochly-Rosen, Daria;
- Chuang, Lee-Ming
Publication type:
Article
Optimizing Human Health Span and Life Span: Insights From Okinawa and Hawaii.
Published in:
Annual Review of Gerontology & Geriatrics, 2013, v. 33, n. 1, p. 135, doi. 10.1891/0198-8794.33.135
By:
- Wilicox, Bradley J.;
- Suzuki, Makoto;
- Donlon, Timothy A.;
- Qimei He;
- Grove, John S.;
- Masaki, Kamal H.;
- Willcox, D. Craig
Publication type:
Article
Association of a common polymorphism in the human GH1 gene with colorectal neoplasia.
Published in:
2002
By:
- Le Marchand, Loïc;
- Donlon, Timothy;
- Seifried, Ann;
- Kaaks, Rudolf;
- Rinaldi, Sabina;
- Wilkens, Lynne R.;
- Le Marchand, Loïc
Publication type:
journal article
Immunohistochemical and cytogenetic studies indicate that malignant angioendotheliomatosis is a primary intravascular (angiotropic) lymphoma.
Published in:
1990
By:
- Molina, Arturo;
- Lombard, Charles;
- Donlon, Timothy;
- Bangs, Charles D.;
- Dorfman, Ronald F.;
- Molina, A;
- Lombard, C;
- Donlon, T;
- Bangs, C D;
- Dorfman, R F
Publication type:
journal article
Proteomic basis of mortality resilience mediated by FOXO3 longevity genotype.
Published in:
GeroScience, 2023, v. 45, n. 4, p. 2303, doi. 10.1007/s11357-023-00740-6
By:
- Donlon, Timothy A.;
- Morris, Brian J.;
- Chen, Randi;
- Lim, Eunjung;
- Morgen, Eric K.;
- Fortney, Kristen;
- Shah, Naisha;
- Masaki, Kamal H.;
- Willcox, Bradley J.
Publication type:
Article
Extreme longevity variants at the FOXO3 locus may moderate FOXO3 isoform levels.
Published in:
GeroScience, 2022, v. 44, n. 2, p. 1129, doi. 10.1007/s11357-021-00431-0
By:
- Frankum, Ryan;
- Jameson, Tom S. O.;
- Knight, Bridget A.;
- Stephens, Francis B.;
- Wall, Benjamin T.;
- Donlon, Timothy A.;
- Torigoe, Trevor;
- Willcox, Bradley J.;
- Willcox, D. Craig;
- Allsopp, Richard C.;
- Harries, Lorna W.
Publication type:
Article
Correction to: Extreme longevity variants at the FOXO3 locus may moderate FOXO3 isoform levels.
Published in:
2022
By:
- Frankum, Ryan;
- Jameson, Tom S. O.;
- Knight, Bridget A.;
- Stephens, Francis B.;
- Wall, Benjamin T.;
- Donlon, Timothy A.;
- Torigoe, Trevor;
- Willcox, Bradley J.;
- Willcox, D. Craig;
- Allsopp, Richard C.;
- Harries, Lorna W.
Publication type:
Correction Notice
Association Analysis of FOXO3 Longevity Variants With Blood Pressure and Essential Hypertension.
Published in:
American Journal of Hypertension, 2016, v. 29, n. 11, p. 1292, doi. 10.1093/ajh/hpv171
By:
- Morris, Brian J.;
- Chen, Randi;
- Donlon, Timothy A.;
- Evans, Daniel S.;
- Tranah, Gregory J.;
- Parimi, Neeta;
- Ehret, Georg B.;
- Newton-Cheh, Christopher;
- Seto, Todd;
- Willcox, D. Craig;
- Masaki, Kamal H.;
- Kei Kamide;
- Hirochika Ryuno;
- Ryosuke Oguro;
- Chikako Nakama;
- Mai Kabayama;
- Koichi Yamamoto;
- Ken Sugimoto;
- Kazunori Ikebe;
- Yukie Masui
Publication type:
Article
Genetic Variation in the Raptor Gene Is Associated With Overweight But Not Hypertension in American Men of Japanese Ancestry.
Published in:
American Journal of Hypertension, 2015, v. 28, n. 4, p. 508, doi. 10.1093/ajh/hpu188
By:
- Morris, Brian J.;
- Carnes, Bruce A.;
- Chen, Randi;
- Donlon, Timothy A.;
- He, Qimei;
- Grove, John S.;
- Masaki, Kamal H.;
- Elliott, Ayako;
- Willcox, Donald C.;
- Allsopp, Richard;
- Willcox, Bradley J.
Publication type:
Article
Genome-Wide Linkage Analysis of Lipids in Nondiabetic Chinese and Japanese From the SAPPHIRe Family Study
Published in:
American Journal of Hypertension, 2006, v. 19, n. 12, p. 1270, doi. 10.1016/j.amjhyper.2006.05.004
By:
- Hsiao, Chin-Fu;
- Chiu, Yen-Feng;
- Chiang, Fu-Tien;
- Ho, Low-Tone;
- Lee, Wen-Jane;
- Hung, Yi-Jen;
- Chen, Yii-Der I.;
- Donlon, Timothy A.;
- Jorgenson, Eric;
- Curb, David;
- Risch, Neil;
- Hsiung, Chao A.
Publication type:
Article
Midlife Risk Factors and Healthy Survival in Men.
Published in:
JAMA: Journal of the American Medical Association, 2006, v. 296, n. 19, p. 2343, doi. 10.1001/jama.296.19.2343
By:
- Willcox, Bradley J.;
- Qimei He;
- Chen, Randi;
- Yano, Katsuhiko;
- Masaki, Kamal H.;
- Grove, John S.;
- Donlon, Timothy A.;
- Willcox, D. Craig;
- Curb, J. David
Publication type:
Article
How much should we eat? The association between energy intake and mortality in a 36-year follow-up study of Japanese-American men.
Published in:
2004
By:
- Willcox BJ;
- Yano K;
- Chen R;
- Willcox DC;
- Rodriguez BL;
- Masaki KH;
- Donlon T;
- Tanaka B;
- Curb JD;
- Willcox, Bradley J;
- Yano, Katsuhiko;
- Chen, Randi;
- Willcox, D Craig;
- Rodriguez, Beatriz L;
- Masaki, Kamal H;
- Donlon, Timothy;
- Tanaka, Brandi;
- Curb, J David
Publication type:
journal article
How Much Should We Eat? The Association Between Energy Intake and Mortality in a 36-Year Follow-Up Study of Japanese-American Men.
Published in:
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2004, v. 59, n. 8, p. 789, doi. 10.1093/gerona/59.8.B789
By:
- Willcox, Bradley J.;
- Yano, Katsuhiko;
- Chen, Randi;
- Willcox, D. Craig;
- Rodriguez, Beatriz L.;
- Masaki, Kamal H.;
- Donlon, Timothy;
- Tanaka, Brandi;
- Curb, J. David
Publication type:
Article
Late-Life Factors Associated with Healthy Aging in Older Men.
Published in:
Journal of the American Geriatrics Society, 2014, v. 62, n. 5, p. 880, doi. 10.1111/jgs.12796
By:
- Bell, Christina L.;
- Chen, Randi;
- Masaki, Kamal;
- Yee, Priscilla;
- He, Qimei;
- Grove, John;
- Donlon, Timothy;
- Curb, J. David;
- Willcox, D. Craig;
- Poon, Leonard W.;
- Willcox, Bradley J.
Publication type:
Article
Circulating microRNA profile of long‐lived Okinawans identifies novel potential targets for optimizing lifespan and health span.
Published in:
Aging Cell, 2024, v. 23, n. 8, p. 1, doi. 10.1111/acel.14191
By:
- Noureddine, Sarah;
- Schneider, Augusto;
- Strader, Sydney;
- Zhu, Xiang;
- Dhahbi, Joseph;
- Allsopp, Richard;
- Willcox, D. Craig;
- Donlon, Timothy A.;
- Shimabukuro, Michio;
- Higa, Moritake;
- Suzuki, Makoto;
- Torigoe, Trevor;
- Ashiqueali, Sarah;
- Yadav, Hariom;
- Willcox, Bradley J.;
- Masternak, Michal M.
Publication type:
Article
FOXO3 longevity interactome on chromosome 6.
Published in:
Aging Cell, 2017, v. 16, n. 5, p. 1016, doi. 10.1111/acel.12625
By:
- Donlon, Timothy A.;
- Morris, Brian J.;
- Chen, Randi;
- Masaki, Kamal H.;
- Allsopp, Richard C.;
- Willcox, D. Craig;
- Elliott, Ayako;
- Willcox, Bradley J.
Publication type:
Article
The FoxO3 gene and cause-specific mortality.
Published in:
Aging Cell, 2016, v. 15, n. 4, p. 617, doi. 10.1111/acel.12452
By:
- Willcox, Bradley J.;
- Tranah, Gregory J.;
- Chen, Randi;
- Morris, Brian J.;
- Masaki, Kamal H.;
- He, Qimei;
- Willcox, D. Craig;
- Allsopp, Richard C.;
- Moisyadi, Stefan;
- Poon, Leonard W.;
- Rodriguez, Beatriz;
- Newman, Anne B.;
- Harris, Tamara B.;
- Cummings, Steven R.;
- Liu, Yongmei;
- Parimi, Neeta;
- Evans, Daniel S.;
- Davy, Phil;
- Gerschenson, Mariana;
- Donlon, Timothy A.
Publication type:
Article
Common PCSK1 Haplotypes Are Associated With Obesity in the Chinese Population.
Published in:
Obesity (19307381), 2010, v. 18, n. 7, p. 1404, doi. 10.1038/oby.2009.390
By:
- Yi-Cheng Chang;
- Yen-Feng Chiu;
- Kuang-Chung Shih;
- Ming-Wei Lin;
- Wayne Huey-Herng Sheu;
- Timothy Donlon;
- Jess David Curb;
- Yuh-Shan Jou;
- Tien-Jyun Chang;
- Hung-Yuan Li;
- Lee-Ming Chuang
Publication type:
Article
Determination of the breakpoint of the common α-thalassaemia deletion in Filipinos in Hawaii.
Published in:
British Journal of Haematology, 1999, v. 104, n. 2, p. 284, doi. 10.1046/j.1365-2141.1999.01175.x
By:
- Hunt, John A.;
- Lee, Lara;
- Donlon, Timothy A.;
- Hsia, Y. Edward;
- Hunt
Publication type:
Article

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