Title: Front Cover: Pd/Zn Co‐catalyzed Asymmetric Ring‐Opening Reactions of Aza/Oxabicyclic Alkenes with Oximes (Asian J. Org. Chem. 1/2019).
Authors: Shen, Guoli; Khan, Ruhima; Yang, Fan; Yang, Yong; Pu, Dongdong; Gao, Yang; Zhan, Yong; Luo, Yang; Fan, Baomin
Abstract: An asymmetric ring‐opening reaction of aza/oxabicyclic alkenes with aromatic oximes was established. The reaction was co‐catalyzed by Pd(OAc)2 and zinc triflate with (R)‐DIFLUORPHOS as the chiral ligand, affording cis‐stereoselective asymmetric ring‐opening products. A synthetic application of this method has been demonstrated by transforming the products to chiral amino alcohols and chiral vicinal diols. More information can be found in the Communication by Yong Yang, Baomin Fan et al. on page 97 in Issue 1, 2019 (DOI: 10.1002/ajoc.201800569).
Subjects: PALLADIUM catalysts; RING-opening reactions; ALKENES
Publication: Asian Journal of Organic Chemistry, 2019, Vol 8, Issue 1, p1
ISSN: 2193-5807
Publication type: Academic Journal
DOI: 10.1002/ajoc.201800696

Front Cover: Pd/Zn Co‐catalyzed Asymmetric Ring‐Opening Reactions of Aza/Oxabicyclic Alkenes with Oximes (Asian J. Org. Chem. 1/2019).

Shen, Guoli; Khan, Ruhima; Yang, Fan; Yang, Yong; Pu, Dongdong; Gao, Yang; Zhan, Yong; Luo, Yang; Fan, Baomin