Works matching DE "RAS proteins"

Results: 978

Site-specific monoubiquitination activates Ras by impeding GTPase-activating protein function.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 1, p. 46, doi. 10.1038/nsmb.2430

By:

Baker, Rachael;
Lewis, Steven M;
Sasaki, Atsuo T;
Wilkerson, Emily M;
Locasale, Jason W;
Cantley, Lewis C;
Kuhlman, Brian;
Dohlman, Henrik G;
Campbell, Sharon L

Publication type:

Article

Grb-ing hold of insulin signaling.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 8, p. 803, doi. 10.1038/nsmb0809-803

By:

Ceccarelli, Derek F. J.;
Sicheri, Frank

Publication type:

Article

Tumor suppressor p53 restricts Ras stimulation of RhoA and cancer cell motility.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 3, p. 215, doi. 10.1038/nsmb1208

By:

Xia, Mingxuan;
Land, Hartmut

Publication type:

Article

Elevation of Intracellular cAMP Levels by Dominant Active Heterotrimeric G Protein Alpha Subunits ScGP-A and ScGP-C in Homobasidiomycete, Schiophyllum commune.

Published in:

Bioscience, Biotechnology & Biochemistry, 2004, v. 68, n. 5, p. 1017, doi. 10.1271/bbb.68.1017

By:

Yamagishi, Kenji;
Kimura, Toshiyuki;
Suzuki, Masahiro;
Shinmoto, Hiroshi;
Yamaki, Ko-ji

Publication type:

Article

High Pressure Promotes Binding of the Allosteric Inhibitor Zn2+‐Cyclen in Crystals of Activated H‐Ras.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 35, p. 1, doi. 10.1002/chem.202400304

By:

Girard, Eric;
Lopes, Pedro;
Spoerner, Michael;
Dhaussy, Anne‐Claire;
Prangé, Thierry;
Kalbitzer, Hans Robert;
Colloc'h, Nathalie

Publication type:

Article

Des3PI: a fragment-based approach to design cyclic peptides targeting protein–protein interactions.

Published in:

Journal of Computer-Aided Molecular Design, 2022, v. 36, n. 8, p. 605, doi. 10.1007/s10822-022-00468-z

By:

Delaunay, Maxence;
Ha-Duong, Tâp

Publication type:

Article

Biographies.

Published in:: Cancer & Metastasis Reviews, 2021, v. 40, n. 3, p. 657, doi. 10.1007/s10555-021-09984-0
Publication type:: Article

Guest editorial/preface.

Published in:

2020

By:

Tímár, József

Publication type:

Editorial

Novel regulation of Ras proteins by direct tyrosine phosphorylation and dephosphorylation.

Published in:

Cancer & Metastasis Reviews, 2020, v. 39, n. 4, p. 1067, doi. 10.1007/s10555-020-09918-2

By:

Buday, László;
Vas, Virág

Publication type:

Article

Dynamically encoded reactivity of Ras enzymes: opening new frontiers for drug discovery.

Published in:

Cancer & Metastasis Reviews, 2020, v. 39, n. 4, p. 1075, doi. 10.1007/s10555-020-09917-3

By:

Pálfy, Gyula;
Menyhárd, Dóra K.;
Perczel, András

Publication type:

Article

Structure-based inhibitor design of mutant RAS proteins—a paradigm shift.

Published in:

Cancer & Metastasis Reviews, 2020, v. 39, n. 4, p. 1091, doi. 10.1007/s10555-020-09914-6

By:

Nyíri, Kinga;
Koppány, Gergely;
Vértessy, Beáta G.

Publication type:

Article

The effects of mutant Ras proteins on the cell signalome.

Published in:

Cancer & Metastasis Reviews, 2020, v. 39, n. 4, p. 1051, doi. 10.1007/s10555-020-09912-8

By:

Takács, Tamás;
Kudlik, Gyöngyi;
Kurilla, Anita;
Szeder, Bálint;
Buday, László;
Vas, Virag

Publication type:

Article

Small molecule inhibitors of RAS proteins with oncogenic mutations.

Published in:

Cancer & Metastasis Reviews, 2020, v. 39, n. 4, p. 1107, doi. 10.1007/s10555-020-09911-9

By:

Orgován, Zoltán;
Keserű, György M.

Publication type:

Article

Clinical report of a brain magnetic resonance imaging finding in Noonan syndrome.

Published in:

2021

By:

D'Amico, Alessandra;
Cipullo, Maria Brunella;
Falco, Mariateresa;
Ugga, Lorenzo;
Melis, Daniela

Publication type:

Case Study

Mechanism of farnesylated CAAX protein processing by the intramembrane protease Rce1.

Published in:

Nature, 2013, v. 504, n. 7479, p. 301, doi. 10.1038/nature12754

By:

Manolaridis, Ioannis;
Kulkarni, Kiran;
Dodd, Roger B.;
Ogasawara, Satoshi;
Zhang, Ziguo;
Bineva, Ganka;
O'Reilly, Nicola;
Hanrahan, Sarah J.;
Thompson, Andrew J.;
Cronin, Nora;
Iwata, So;
Barford, David

Publication type:

Article

Stem cells: Dual response to Ras mutation.

Published in:

Nature, 2013, v. 504, n. 7478, p. 91, doi. 10.1038/nature12840

By:

Chu, S. Haihua;
Armstrong, Scott A.

Publication type:

Article

Drug discovery: Pocket of opportunity.

Published in:

Nature, 2013, v. 503, n. 7477, p. 475, doi. 10.1038/nature12835

By:

Bollag, Gideon;
Zhang, Chao

Publication type:

Article

Advances in Targeting KRAS G12C in Gastrointestinal Malignancies: Focus on KRAS G12C Inhibitors.

Published in:

touchREVIEWS in Oncology & Haematology, 2024, v. 20, n. 2, p. 25, doi. 10.17925/OHR.2024.20.2.7

By:

Hoyek, Celine;
Pirozzi, Angelo;
Jones, Jeremy;
Rimassa, Lorenza;
Sonbol, Mohamad B.;
Bekaii-Saab, Tanios

Publication type:

Article

ANÁLISE DE ESTRATÉGIAS TERAPÊUTICAS PARA O ONCOGENE KRAS EM CÂNCER DE PULMÃO DE CÉLULAS NÃO PEQUENAS.

Published in:

Revista Foco (Interdisciplinary Studies Journal), 2024, v. 17, n. 12, p. 1, doi. 10.54751/revistafoco.v17n12-029

By:

Guimarães da Silva, Jaeanne Fabian;
Marinho da Silva, Thavia Witoria;
Lima Neves, Walter Luiz;
de Oliveira Rezende, Gabriel

Publication type:

Article

RAS: Target for Cancer Therapy.

Published in:

Cancer Investigation, 2008, v. 26, n. 9, p. 948, doi. 10.1080/07357900802087275

By:

Saxena, Nandita;
Lahiri, Sitanshu Sekhar;
Hambarde, Shashank;
Tripathi, Rajendra Prasad

Publication type:

Article

Transcriptional Profile of Ki-Ras-Induced Transformation of Thyroid Cells.

Published in:

Cancer Investigation, 2007, v. 25, n. 4, p. 256, doi. 10.1080/07357900701206406

By:

Visconti, Roberta;
Federico, Antonella;
Coppola, Valeria;
Pentimalli, Francesca;
Berlingieri, Maria Teresa;
Pallante, Pierlorenzo;
Kruhoffer, Mogens;
Orntoft, Torben F.;
Fusco, Alfredo

Publication type:

Article

Farnesyltransferase Inhibitors in Breast Cancer Therapy.

Published in:

Cancer Investigation, 2002, v. 20, p. 30, doi. 10.1081/CNV-120014884

By:

Dy, Grace K.;
Adjei, Alex A.

Publication type:

Article

Single‐Molecule Bioelectronic Label‐Free Assay of both Protein and Genomic Markers of Pancreatic Mucinous Cysts' in Whole Blood Serum.

Published in:

Advanced Electronic Materials, 2021, v. 7, n. 9, p. 1, doi. 10.1002/aelm.202100304

By:

Macchia, Eleonora;
Sarcina, Lucia;
Driescher, Caroline;
Gounani, Zahra;
Tewari, Amit;
Osterbacka, Ronald;
Palazzo, Gerardo;
Tricase, Angelo;
Kovacs Vajna, Zsolt Miklos;
Viola, Fabrizio;
Modena, Francesco;
Caironi, Mario;
Torricelli, Fabrizio;
Esposito, Irene;
Torsi, Luisa

Publication type:

Article

Physico- and chemical biology using nanomanipulation and micromanipulation technologies.

Published in:

Biophysics & Physicobiology, 2022, v. 19, p. 1, doi. 10.2142/biophysico.bppb-v19.0044

By:

Akira Kitamura;
Ryo Iizuka

Publication type:

Article

Inhibition of Ras activity coordinates cell fusion with cell--cell contact during yeast mating.

Published in:

Journal of Cell Biology, 2018, v. 217, n. 4, p. 1467, doi. 10.1083/jcb.201708195

By:

Merlini, Laura;
Dudin, Omaya;
Michon, Laetitia;
Vincenzetti, Vincent;
Martin, Sophie G.;
Khalili, Bita

Publication type:

Article

RAS SF4 controls SOCE and ER-PM junctions through regulation of PI(4,5)P2.

Published in:

Journal of Cell Biology, 2017, v. 216, n. 7, p. 2011, doi. 10.1083/jcb.201606047

By:

Yu-Ju Chen;
Chi-Lun Chang;
Wan-Ru Lee;
Jen Liou

Publication type:

Article

RASSF4: Regulator of plasma membrane PI(4,5)P2.

Published in:

Journal of Cell Biology, 2017, v. 216, n. 7, p. 1879, doi. 10.1083/jcb.201706042

By:

Dickson, Eamonn J.

Publication type:

Article

VPS35 binds farnesylated N-Ras in the cytosol to regulate N-Ras trafficking.

Published in:

Journal of Cell Biology, 2016, v. 214, n. 4, p. 445, doi. 10.1083/jcb.201604061

By:

Mo Zhou;
Heidi Wiener;
Wenjuan Su;
Yong Zhou;
Liot, Caroline;
Ahearn, Ian;
Hancock, John F.;
Philips, Mark R.

Publication type:

Article

PI(3,5)P2 controls endosomal branched actin dynamics by regulating cortactin-actin interactions.

Published in:

Journal of Cell Biology, 2015, v. 210, n. 5, p. 753, doi. 10.1083/jcb.201412127

By:

Nan Hyung Hong;
Aidong Qi;
Weaver, Alissa M.

Publication type:

Article

Correction.

Published in:: 2012
Publication type:: Correction Notice

The Ras protein superfamily: Evolutionary tree and role of conserved amino acids.

Published in:

Journal of Cell Biology, 2012, v. 196, n. 2, p. 189, doi. 10.1083/jcb.201103008

By:

Rojas, Ana Maria;
Fuentes, Gloria;
Rausell, Antonio;
Valencia, Alfonso

Publication type:

Article

Palmitoylated Ras proteins traffic through recycling endosomes to the plasma membrane during exocytosis.

Published in:

Journal of Cell Biology, 2010, v. 191, n. 1, p. 23, doi. 10.1083/jcb.200911143

By:

Misaki, Ryo;
Morimatsu, Miki;
Uemura, Takefumi;
Waguri, Satoshi;
Miyoshi, Eiji;
Taniguchi, Naoyuki;
Matsuda, Michiyuki;
Taguchi, Tomohiko

Publication type:

Article

Ras-mediated activation of the TORC2-PKB pathway is critical for chemotaxis.

Published in:

Journal of Cell Biology, 2010, v. 190, n. 2, p. 233, doi. 10.1083/jcb.201001129

By:

Cai, Huaqing;
Das, Satarupa;
Kamimura, Yoichiro;
Long, Yu;
Parent, Carole A.;
Devreotes, Peter N.

Publication type:

Article

From autoinhibition to inhibition in trans: the Raf-1 regulatory domain inhibits Rok-α kinase activity.

Published in:

Journal of Cell Biology, 2009, v. 187, n. 3, p. 335, doi. 10.1083/jcb.200906178

By:

Niault, Théodora;
Sobczak, Izabela;
Meissl, Katrin;
Weitsman, Gregory;
Piazzolla, Daniela;
Maurer, Gabriele;
Kern, Florian;
Ehrenreiter, Karin;
Hamerl, Matthias;
Moarefi, Ismail;
Leung, Thomas;
Carugo, Oliviero;
Ng, Tony;
Baccarini, Manuela

Publication type:

Article

Different Rho GTPase-dependent signaling pathways initiate sequential steps in the consolidation of long-term potentiation.

Published in:

Journal of Cell Biology, 2009, v. 186, n. 1, p. 85, doi. 10.1083/jcb.200901084

By:

Rex, Christopher S.;
Chen, Lulu Y.;
Sharma, Anupam;
Liu, Jihua;
Babayan, Alex H.;
Gaily, Christine M.;
Lynch, Gary

Publication type:

Article

A clathrin-dependent pathway leads to KRas signaling on late endosomes en route to lysosomes.

Published in:

Journal of Cell Biology, 2009, v. 184, n. 6, p. 863, doi. 10.1083/jcb.200807186

By:

Lu, Albert;
Tebar, Francesc;
Alvarez-Moya, Blanca;
López-Alcalá, Cristina;
Calvo, Maria;
Enrich, Carlos;
Agell, Neus;
Nakamura, Takeshi;
Matsuda, Michiyuki;
Bachs, Oriol

Publication type:

Article

KRas takes a different route.

Published in:

Journal of Cell Biology, 2009, v. 184, n. 6, p. 766, doi. 10.1083/jcb.1846iti1

By:

Short, Ben

Publication type:

Article

Rab13 regulates membrane trafficking between TGN and recycling endosomes in polarized epithelial cells.

Published in:

Journal of Cell Biology, 2008, v. 182, n. 5, p. 845, doi. 10.1083/jcb.200802176

By:

Nokes, Rita L.;
Fields, Ian C.;
Collins, Ruth N.;
Fölsch, Heike

Publication type:

Article

Better binding with a flick of the tail.

Published in:

Journal of Cell Biology, 2008, v. 182, n. 5, p. 818, doi. 10.1083/jcb.1825iti2

By:

Robinson, Richard;
Williams, Ruth

Publication type:

Article

p190RhoGAP is the convergence point of adhesion signals from α5ß1 integrin and syndecan-4.

Published in:

Journal of Cell Biology, 2008, v. 181, n. 6, p. 1013, doi. 10.1083/jcb.200711129

By:

Bass, Mark D.;
Morgan, Mark R.;
Roach, Kirsty A.;
Settleman, Jeffrey;
Goryachev, Andrew B.;
Humphries, Martin J.

Publication type:

Article

Regulation of atrial natriuretic peptide secretion by a novel Ras-like protein.

Published in:

Journal of Cell Biology, 2007, v. 179, n. 3, p. 527, doi. 10.1083/jcb.200707101

By:

Rybkin, Igor I.;
Mi-Sung Kim;
Bezprozvannaya, Svetlana;
Xiaoxia Qi;
Richardson, James A.;
Plato, Craig F.;
Hill, Joseph A.;
Bassel-Duby, Rhonda;
Olson, Eric N.

Publication type:

Article

Getting a G-RRP on regulated exocytosis in the heart.

Published in:

Journal of Cell Biology, 2007, v. 179, n. 3, p. 371, doi. 10.1083/jcb.200710021

By:

Glembotski, Christopher C.

Publication type:

Article

Darkness descends with two Rabs.

Published in:

Journal of Cell Biology, 2006, v. 175, n. 2, p. 199, doi. 10.1083/jcb.200608058

By:

Marks, Michael S.

Publication type:

Article

RLIP76 (RalBP1) is an R-Ras effector that mediates adhesion-dependent Rac activation and cell migration.

Published in:

Journal of Cell Biology, 2006, v. 174, n. 6, p. 877, doi. 10.1083/jcb.200603111

By:

Goldfinger, Lawrence E.;
Ptak, Celeste;
Jeffery, Erin D.;
Shabanowitz, Jeffrey;
Hunt, Donald F.;
Ginsberg, Mark H.

Publication type:

Article

Possible modifier genes in the variation of neurofibromatosis type 1 clinical phenotypes.

Published in:

Journal of Neurogenetics, 2018, v. 32, n. 2, p. 65, doi. 10.1080/01677063.2018.1456538

By:

Sharafi, Parisa;
Ayter, Sükriye

Publication type:

Article

Rab11 and Its Role in Neurodegenerative Diseases.

Published in:

ASN Neuro (Sage Publications, Ltd.), 2022, p. 1, doi. 10.1177/17590914221142360

By:

Sultana, Pinky;
Novotny, Jiri

Publication type:

Article

Rab11 and Its Role in Neurodegenerative Diseases.

Published in:

ASN Neuro (Sage Publications, Ltd.), 2022, v. 14, p. 1, doi. 10.1177/17590914221142360

By:

Sultana, Pinky;
Novotny, Jiri

Publication type:

Article

Stochastic analysis of MMR proteins and KRAS in biological fluids for pathological features prediction in colorectal adenocarcinoma patients.

Published in:

Oncolog-Hematolog, 2024, v. 69, n. 4, p. 24

By:

Bratei, Alexandru-Adrian;
van Staden, Raluca-Ioana

Publication type:

Article

乳腺癌组织 FOXP3、HMGA2、RASAL2 的表达及与临床病理特征和预后的关系.

Published in:

Progress in Modern Biomedicine, 2021, v. 21, n. 20, p. 3959, doi. 10.13241/j.cnki.pmb.2021.20.032

By:

李会芳;
侯永强;
王明军;
陈涛;
刘金彪

Publication type:

Article

vmiR-382-3p 靶向 RASA1 基因调控骨关节炎软骨细胞增殖和凋亡.

Published in:

Progress in Modern Biomedicine, 2020, v. 20, n. 13, p. 2440, doi. 10.13241/j.cnki.pmb.2020.13.008

By:

GILDAS ALOGO YING;
焦建宝;
梁东星;
任路通;
王一凡;
王康

Publication type:

Article