Works matching DE "HIGH throughput screening (Drug development)"

Results: 2782

Immune-enrichment Predicts Response to Trastuzumab.

Published in:: Oncology (08909091), 2014, v. 28, n. 7, p. III
Publication type:: Article

High-throughput identification and rational design of synergistic small-molecule pairs for combating and bypassing antibiotic resistance.

Published in:

PLoS Biology, 2017, v. 15, n. 6, p. 1, doi. 10.1371/journal.pbio.2001644

By:

Wambaugh, Morgan A.;
Shakya, Viplendra P. S.;
Lewis, Adam J.;
Mulvey, Matthew A.;
Brown, Jessica C. S.

Publication type:

Article

Computer‐Aided Synthesis Planning (CASP) and Machine Learning: Optimizing Chemical Reaction Conditions.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 55, p. 1, doi. 10.1002/chem.202401626

By:

Han, Yu;
Deng, Mingjing;
Liu, Ke;
Chen, Jia;
Wang, Yuting;
Xu, Yu‐Ning;
Dian, Longyang

Publication type:

Article

Front Cover: Discovering of Atomically Precise Metal Nanoclusters by High‐Throughput Syntheses Platform (Chem. Eur. J. 53/2024).

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 53, p. 1, doi. 10.1002/chem.202485301

By:

Tang, Li;
Wang, Li;
Wang, Bin;
Pei, Yong;
Wang, Shuxin

Publication type:

Article

Empowering Protein Engineering through Recombination of Beneficial Substitutions.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 16, p. 1, doi. 10.1002/chem.202303889

By:

Wang, Xinyue;
Li, Anni;
Li, Xiujuan;
Cui, Haiyang

Publication type:

Article

Controlling the Crystallisation and Hydration State of Crystalline Porous Organic Salts.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 64, p. 1, doi. 10.1002/chem.202302420

By:

O'Shaughnessy, Megan;
Padgham, Alex C.;
Clowes, Rob;
Little, Marc A.;
Brand, Michael C.;
Qu, Hang;
Slater, Anna G.;
Cooper, Andrew I.

Publication type:

Article

Chiroptical Recognition of Carboxylates with Charge‐Neutral Double‐Stranded Zinc(II) Helicates.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 61, p. 1, doi. 10.1002/chem.202301613

By:

Kalarikkal, Malavika G.;
Drechsler, Christoph;
Tusha, Gers;
Schäfer, Lars V.;
Van Craen, David

Publication type:

Article

Combining Molecular Quantum Mechanical Modeling and Machine Learning for Accelerated Reaction Screening and Discovery.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 60, p. 1, doi. 10.1002/chem.202301957

By:

Casetti, Nicholas;
Alfonso‐Ramos, Javier E.;
Coley, Connor W.;
Stuyver, Thijs

Publication type:

Article

A Small‐Molecule Probe with a Dual Function of miRNA Inhibition and Target identification.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 3, p. 1, doi. 10.1002/chem.202202013

By:

Wang, Weishan;
Deng, Jiafang;
Zhang, Yan;
Li, Jinbo

Publication type:

Article

High‐Throughput Screening of Heterogeneous Transition Metal Dual‐Atom Catalysts by Synergistic Effect for Nitrate Reduction to Ammonia.

Published in:

Advanced Functional Materials, 2023, v. 33, n. 32, p. 1, doi. 10.1002/adfm.202301493

By:

Shu, Zheng;
Chen, Hongfei;
Liu, Xing;
Jia, Huaxian;
Yan, Hejin;
Cai, Yongqing

Publication type:

Article

High‐Throughput Screening Thickness‐Dependent Resistive Switching in SrTiO3 Thin Films for Robust Electronic Synapse.

Published in:

Advanced Functional Materials, 2023, v. 33, n. 23, p. 1, doi. 10.1002/adfm.202213874

By:

Tang, Mingkai;
Dai, Liyufen;
Cheng, Mingqiang;
Zhang, Yuan;
Wang, Yanghe;
Zhong, Xiangli;
Wang, Jinbin;
An, Feng;
Ma, Ming;
Huang, Mingqiang;
Li, Changjian;
Li, Jiangyu;
Zhong, Gaokuo

Publication type:

Article

Integrated Microsystem Toward High‐Throughput Automated Green Synthesis and Raman Enhancement Performance Screening of Noble‐Metal@Cu‐MOF.

Published in:

Advanced Functional Materials, 2023, v. 33, n. 11, p. 1, doi. 10.1002/adfm.202211845

By:

Fan, Chuan;
Luo, Yong;
Tian, Meng;
Zhou, Mengyun;
Wang, Lirong;
Xu, Tailin;
Zhang, Xueji

Publication type:

Article

High‐Throughput Screening Assisted Discovery of a Stable Layered Anti‐Ferromagnetic Semiconductor: CdFeP2Se6.

Published in:

Advanced Functional Materials, 2023, v. 33, n. 9, p. 1, doi. 10.1002/adfm.202210965

By:

Kothakonda, Manish;
Zhu, Yanglin;
Guan, Yingdong;
He, Jingyang;
Kidd, Jamin;
Zhang, Ruiqi;
Ning, Jinliang;
Gopalan, Venkatraman;
Xie, Weiwei;
Mao, Zhiqiang;
Sun, Jianwei

Publication type:

Article

Off‐Stoichiometry Quaternary Heusler‐Like Semiconductors with Magnetism and Disorder.

Published in:

Advanced Functional Materials, 2022, v. 32, n. 51, p. 1, doi. 10.1002/adfm.202209233

By:

Ruan, Yurong;
Zhong, Ke;
Zhang, Ying;
Zhang, Fang;
Zhang, Yubo;
Zhang, Wenqing

Publication type:

Article

High‐Entropy Catalyst—A Novel Platform for Electrochemical Water Splitting.

Published in:

Advanced Functional Materials, 2022, v. 32, n. 47, p. 1, doi. 10.1002/adfm.202207536

By:

Zhai, Yiyue;
Ren, Xiangrong;
Wang, Bolun;
Liu, Shengzhong

Publication type:

Article

A Nanoplasmonic Portable Molecular Interaction Platform for High‐Throughput Drug Screening.

Published in:

Advanced Functional Materials, 2022, v. 32, n. 46, p. 1, doi. 10.1002/adfm.202203635

By:

Fan, Hongli;
Huang, Liping;
Li, Rui;
Chen, Mingqian;
Huang, Junjie;
Xu, Hao;
Hu, Wenjun;
Liu, Gang L.

Publication type:

Article

Discovery of Efficient Visible‐light Driven Oxygen Evolution Photocatalysts: Automated High‐Throughput Computational Screening of MA2Z4.

Published in:

Advanced Functional Materials, 2022, v. 32, n. 45, p. 1, doi. 10.1002/adfm.202207415

By:

Lin, Chao;
Feng, Xiang;
Legut, Dominik;
Liu, Xiaopeng;
Seh, Zhi Wei;
Zhang, Ruifeng;
Zhang, Qianfan

Publication type:

Article

Graphene‐Based Nucleants for Protein Crystallization.

Published in:

Advanced Functional Materials, 2022, v. 32, n. 42, p. 1, doi. 10.1002/adfm.202202596

By:

Govada, Lata;
Rubio, Noelia;
Saridakis, Emmanuel;
Balaskandan, Kalpana;
Leese, Hannah S.;
Li, Yanmin;
Wang, Beijia;
Shaffer, Milo S. P.;
Chayen, Naomi

Publication type:

Article

Two‐Dimensional Perovskites with Tunable Room‐Temperature Phosphorescence.

Published in:

Advanced Functional Materials, 2022, v. 32, n. 39, p. 1, doi. 10.1002/adfm.202204579

By:

Wu, Yilei;
Lu, Shuaihua;
Zhou, Qionghua;
Ju, Ming‐Gang;
Zeng, Xiao Cheng;
Wang, Jinlan

Publication type:

Article

Artificial Intelligence‐Assisted High‐Throughput Screening of Printing Conditions of Hydrogel Architectures for Accelerated Diabetic Wound Healing.

Published in:

Advanced Functional Materials, 2022, v. 32, n. 38, p. 1, doi. 10.1002/adfm.202201843

By:

Chen, Baiqi;
Dong, Jianpei;
Ruelas, Marina;
Ye, Xiangyi;
He, Jinxu;
Yao, Ruijie;
Fu, Yuqiu;
Liu, Ying;
Hu, Jingpeng;
Wu, Tianyu;
Zhou, Cuiping;
Li, Yan;
Huang, Lu;
Zhang, Yu Shrike;
Zhou, Jianhua

Publication type:

Article

Toward the Rational Design of Mid‐Infrared Nonlinear Optical Materials with Targeted Properties via a Multi‐Level Data‐Driven Approach.

Published in:

Advanced Functional Materials, 2022, v. 32, n. 23, p. 1, doi. 10.1002/adfm.202200231

By:

Cai, Wenbing;
Abudurusuli, Ailijiang;
Xie, Congwei;
Tikhonov, Evgenii;
Li, Junjie;
Pan, Shilie;
Yang, Zhihua

Publication type:

Article

Next Generation Cell Culture Tools Featuring Micro‐ and Nanotopographies for Biological Screening (Adv. Funct. Mater. 3/2022).

Published in:

Advanced Functional Materials, 2022, v. 32, n. 3, p. 1, doi. 10.1002/adfm.202270023

By:

Carthew, James;
Abdelmaksoud, Hazem H.;
Cowley, Karla J.;
Hodgson‐Garms, Margeaux;
Elnathan, Roey;
Spatz, Joachim P.;
Brugger, Juergen;
Thissen, Helmut;
Simpson, Kaylene J.;
Voelcker, Nicolas H.;
Frith, Jessica E.;
Cadarso, Victor J.

Publication type:

Article

Next Generation Cell Culture Tools Featuring Micro‐ and Nanotopographies for Biological Screening.

Published in:

Advanced Functional Materials, 2022, v. 32, n. 3, p. 1, doi. 10.1002/adfm.202100881

By:

Carthew, James;
Abdelmaksoud, Hazem H.;
Cowley, Karla J.;
Hodgson‐Garms, Margeaux;
Elnathan, Roey;
Spatz, Joachim P.;
Brugger, Juergen;
Thissen, Helmut;
Simpson, Kaylene J.;
Voelcker, Nicolas H.;
Frith, Jessica E.;
Cadarso, Victor J.

Publication type:

Article

TiO2/MXene‐Assisted LDI‐MS for Urine Metabolic Profiling in Urinary Disease.

Published in:

Advanced Functional Materials, 2021, v. 31, n. 52, p. 1, doi. 10.1002/adfm.202106743

By:

Chen, Junyu;
Li, Yuze;
Jiang, Yuming;
Mao, Liucheng;
Lai, Mi;
Jiang, Lixia;
Liu, Huihui;
Nie, Zongxiu

Publication type:

Article

Single‐Cell Microgels for Diagnostics and Therapeutics.

Published in:

Advanced Functional Materials, 2021, v. 31, n. 44, p. 1, doi. 10.1002/adfm.202009946

By:

Dubay, Ryan;
Urban, Joseph N.;
Darling, Eric M.

Publication type:

Article

High‐Throughput Screening for Phase‐Change Memory Materials.

Published in:

Advanced Functional Materials, 2021, v. 31, n. 21, p. 1, doi. 10.1002/adfm.202009803

By:

Liu, Yu‐Ting;
Li, Xian‐Bin;
Zheng, Hui;
Chen, Nian‐Ke;
Wang, Xue‐Peng;
Zhang, Xu‐Lin;
Sun, Hong‐Bo;
Zhang, Shengbai

Publication type:

Article

Expanding the chemical diversity of CK2 inhibitors.

Published in:

Molecular & Cellular Biochemistry, 2008, v. 316, n. 1/2, p. 71

By:

Caroline Barette;
Jacques Einhorn;
Cathy Einhorn;
Jean-Noel Denis;
Gilles Bisson;
Laurence Lafanechere

Publication type:

Article

ChemFlow_py: a flexible toolkit for docking and rescoring.

Published in:

Journal of Computer-Aided Molecular Design, 2023, v. 37, n. 11, p. 565, doi. 10.1007/s10822-023-00527-z

By:

Monari, Luca;
Galentino, Katia;
Cecchini, Marco

Publication type:

Article

Integrated data-driven and experimental approaches to accelerate lead optimization targeting SARS-CoV-2 main protease.

Published in:

Journal of Computer-Aided Molecular Design, 2023, v. 37, n. 8, p. 339, doi. 10.1007/s10822-023-00509-1

By:

Varikoti, Rohith Anand;
Schultz, Katherine J.;
Kombala, Chathuri J.;
Kruel, Agustin;
Brandvold, Kristoffer R.;
Zhou, Mowei;
Kumar, Neeraj

Publication type:

Article

In silico identification and in vitro antiviral validation of potential inhibitors against Chikungunya virus.

Published in:

Journal of Computer-Aided Molecular Design, 2022, v. 36, n. 7, p. 521, doi. 10.1007/s10822-022-00463-4

By:

Verma, Jyoti;
Hasan, Abdul;
Sunil, Sujatha;
Subbarao, Naidu

Publication type:

Article

SAMPL7 protein-ligand challenge: A community-wide evaluation of computational methods against fragment screening and pose-prediction.

Published in:

Journal of Computer-Aided Molecular Design, 2022, v. 36, n. 4, p. 291, doi. 10.1007/s10822-022-00452-7

By:

Grosjean, Harold;
Işık, Mehtap;
Aimon, Anthony;
Mobley, David;
Chodera, John;
von Delft, Frank;
Biggin, Philip C

Publication type:

Article

Target identification for repurposed drugs active against SARS-CoV-2 via high-throughput inverse docking.

Published in:

Journal of Computer-Aided Molecular Design, 2022, v. 36, n. 1, p. 25, doi. 10.1007/s10822-021-00432-3

By:

Ribone, Sergio R.;
Paz, S. Alexis;
Abrams, Cameron F.;
Villarreal, Marcos A.

Publication type:

Article

High-throughput virtual screening and preclinical analysis identifies CB-1, a novel potent dual B-Raf/c-Raf inhibitor, effective against wild and mutant variants of B-Raf expression in colorectal carcinoma.

Published in:

Journal of Computer-Aided Molecular Design, 2021, v. 35, n. 12, p. 1165, doi. 10.1007/s10822-021-00426-1

By:

Al Shahrani, Mesfer;
Abohassan, Mohammad;
Y. Alshahrani, Mohammad;
Hakami, Abdulrahim R.;
Rajagopalan, Prasanna

Publication type:

Article

Congestion game scheduling for virtual drug screening optimization.

Published in:

Journal of Computer-Aided Molecular Design, 2018, v. 32, n. 2, p. 363, doi. 10.1007/s10822-017-0093-7

By:

Nikitina, Natalia;
Ivashko, Evgeny;
Tchernykh, Andrei

Publication type:

Article

Effects of histidine protonation and rotameric states on virtual screening of M. tuberculosis RmlC.

Published in:

Journal of Computer-Aided Molecular Design, 2013, v. 27, n. 3, p. 235, doi. 10.1007/s10822-013-9643-9

By:

Kim, Meekyum;
Nichols, Sara;
Wang, Yi;
McCammon, J.

Publication type:

Article

A reverse combination of structure-based and ligand-based strategies for virtual screening.

Published in:

Journal of Computer-Aided Molecular Design, 2012, v. 26, n. 3, p. 319, doi. 10.1007/s10822-012-9558-x

By:

Cortés-Cabrera, Álvaro;
Gago, Federico;
Morreale, Antonio

Publication type:

Article

Fragment-based drug discovery: what really works. An interview with Sandy Farmer of Boehringer Ingelheim.

Published in:

2011

By:

Warr, Wendy A.

Publication type:

Interview

Novel isoquinolone PDK1 inhibitors discovered through fragment-based lead discovery.

Published in:

Journal of Computer-Aided Molecular Design, 2011, v. 25, n. 7, p. 689, doi. 10.1007/s10822-011-9456-7

By:

Johnson, M. Catherine;
Qiyue Hu;
Lingardo, Laura;
Ferre, Rose Ann;
Greasley, Samantha;
Jiangli Yan;
Kath, John;
Ping Chen;
Ermolieff, Jacques;
Alton, Gordon

Publication type:

Article

Fragment-based drug discovery.

Published in:

Journal of Computer-Aided Molecular Design, 2009, v. 23, n. 8, p. 453, doi. 10.1007/s10822-009-9292-1

By:

Warr, Wendy A.

Publication type:

Article

Virtual screening applications: a study of ligand-based methods and different structure representations in four different scenarios.

Published in:

Journal of Computer-Aided Molecular Design, 2007, v. 21, n. 10/11, p. 617, doi. 10.1007/s10822-007-9145-8

By:

Hristozov, Dimitar P.;
Oprea, Tudor I.;
Gasteiger, Johann

Publication type:

Article

Surrogate docking: structure-based virtual screening at high throughput speed.

Published in:

Journal of Computer-Aided Molecular Design, 2005, v. 19, n. 7, p. 483, doi. 10.1007/s10822-005-9002-6

By:

Sukjoon Yoon;
Smellie, Andrew;
Hartsough, David;
Filikov, Anton

Publication type:

Article

Selection criteria for drug-like compounds.

Published in:

Medicinal Research Reviews, 2003, v. 23, n. 3, p. 302, doi. 10.1002/med.10041

By:

Ingo Muegge

Publication type:

Article

Osteoarthritis—Slow but Steady Steps Forward.

Published in:

2021

By:

Gallagher, J. A.

Publication type:

Editorial

Use of an online surveillance system for screening drug interactions in prescriptions in community pharmacies.

Published in:

European Journal of Clinical Pharmacology, 2006, v. 62, n. 8, p. 661, doi. 10.1007/s00228-006-0149-4

By:

Heikkilä, Tiina;
Lekander, Tuula;
Raunio, Hannu

Publication type:

Article

Screening of a broad range of rice (Oryza sativa L.) germplasm for in vitro rapid plant regeneration and development of an early prediction system.

Published in:

In Vitro Cellular & Developmental Biology Plant, 2009, v. 45, n. 4, p. 414, doi. 10.1007/s11627-008-9174-6

By:

A. Dabul;
H. Belefant-Miller;
M. RoyChowdhury;
J. Hubstenberger;
A. Lorence;
G. Phillips

Publication type:

Article

A New Approach for Studying Poly(ADP-Ribose) Polymerase Inhibitors Using Permeabilized Adherent Cells.

Published in:

Biochemistry (00062979), 2024, v. 89, n. 9, p. 1619, doi. 10.1134/S0006297924090086

By:

Shram, Stanislav I.;
Shcherbakova, Tatyana A.;
Abramova, Tatyana V.;
Smirnovskaya, Maria S.;
Balandina, Anastasia I.;
Kulikov, Andrey V.;
Švedas, Vytas K.;
Silnikov, Vladimir N.;
Myasoedov, Nikolay F.;
Nilov, Dmitry K.

Publication type:

Article

Malaria Parasite Plasmodium falciparum Proteins on the Surface of Infected Erythrocytes as Targets for Novel Drug Discovery.

Published in:

Biochemistry (00062979), 2022, v. 87, n. 1, p. S192, doi. 10.1134/S0006297922140152

By:

Oleinikov, Andrew V.

Publication type:

Article

Enhancing the erythritol production of Yarrowia lipolytica by high-throughput screening based on highly sensitive artificial sensor and anchor protein cwp2.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2024, v. 51, p. 1, doi. 10.1093/jimb/kuae045

By:

Cui, Quan;
Liu, Hui;
Guo, Chuanzhuang;
Wang, Jianbin;
Liu, Yuehan;
Zhao, Yaqi;
Wang, Ruiming;
Li, Piwu;
Wang, Ting;
Wang, Junqing;
Li, Nan

Publication type:

Article

Performance evaluation of a low-throughput qPCR-based Legionella assay for utility as an onsite industrial water system monitoring method.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2024, v. 51, p. 1, doi. 10.1093/jimb/kuae030

By:

Corrigan, Alexsandra;
Niemaseck, Benjamin;
Moore, Mackenzie;
McIlwaine, Douglas;
Duguay, Jeremy

Publication type:

Article

Biosensors for the detection of chorismate and cis,cis-muconic acid in Corynebacterium glutamicum.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2024, v. 51, p. 1, doi. 10.1093/jimb/kuae024

By:

Velasquez-Guzman, Jeanette C;
Huttanus, Herbert M;
Morales, Demosthenes P;
Werner, Tara S;
Carroll, Austin L;
Guss, Adam M;
Yeager, Chris M;
Dale, Taraka;
Jha, Ramesh K

Publication type:

Article