Works matching DE "JAK-STAT pathway"

Results: 1741

Wenqing Yin Attenuates the Allergic Contact Dermatitis Response by Inhibiting the JAK2/STAT1 and MAPK Signaling Pathways.

Published in:

Journal of Inflammation Research, 2025, v. 18, p. 7013, doi. 10.2147/JIR.S512868

By:

Ren, Mengyue;
Li, Siman;
Li, Shaoqiang;
Tan, Zhiwei;
Shi, Jun

Publication type:

Article

Upadacitinib for refractory Behçet's disease with myelodysplastic syndrome and trisomy 8/9: a case report and mechanistic insights.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1609884

By:

Wang, Yukai;
Tian, Feng;
Li, Hui

Publication type:

Article

Myricetin Restores Autophagy to Attenuate Lumbar Intervertebral Disk Degeneration Via Negative Regulation of the JAK2/STAT3 Pathway.

Published in:

Biochemical Genetics, 2025, v. 63, n. 3, p. 2743, doi. 10.1007/s10528-024-10838-x

By:

Mao, Tian;
Fan, Junchi

Publication type:

Article

AURKA promotes angiogenesis in uveal melanoma via activation of the JAK2/STAT3/VEGFA signaling pathway.

Published in:

Cancer Cell International, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12935-025-03836-5

By:

Ma, Qingyue;
Wang, Haowen;
Zhao, Xintong;
Gao, Xiaodi;
Zhang, Qian;
Liu, Yichong;
Ji, Yiqing;
Sun, Ying;
Lei, Ke;
Luo, Wenjuan

Publication type:

Article

CD70 CAR-T cells empowered by TS-2021 through ex vivo transduction show potent antitumor efficacy against glioblastoma.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03431-6

By:

Fang, Sheng;
Wu, Jiankun;
Liu, Yida;
Wang, Peiwen;
Yuan, Guiqiang;
Gao, Jiajia;
Zhang, Wenxin;
Zhang, Junwen;
Liu, Fusheng

Publication type:

Article

VSIG4 Promotes Tumour‐Associated Macrophage M2 Polarization and Immune Escape in Colorectal Cancer via Fatty Acid Oxidation Pathway.

Published in:

Clinical & Translational Medicine, 2025, v. 15, n. 5, p. 1, doi. 10.1002/ctm2.70340

By:

Liu, Jiafeng;
Zhang, WenXin;
Chen, Lu;
Wang, Xinhai;
Mao, Xiang;
Wu, Zimei;
Shi, Huanying;
Qi, Huijie;
Chen, Li;
Huang, Yuxin;
Li, Jiyifan;
Zhong, Mingkang;
Shi, Xiaojin;
Li, Qunyi;
Wang, Tianxiao

Publication type:

Article

Connection between circulating inflammatory cytokines and non-small cell lung cancer: integrated Mendelian randomization and gene function analysis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02817-4

By:

Niu, Ke;
Tang, Jing;
Zhong, Jianxin;
Zheng, Lin;
Zhu, Yayu;
Ling, Huijuan;
Liu, Yu;
Xu, Qing;
Qiu, Ping;
Chen, Liwen

Publication type:

Article

Probiotics ameliorate H. pylori-associated gastric β-catenin and COX-2 carcinogenesis signaling by regulating miR-185.

Published in:

Journal of Biomedical Science, 2025, v. 32, n. 1, p. 1, doi. 10.1186/s12929-025-01149-3

By:

Yang, Yao-Jong;
Wu, Chung-Tai;
Cheng, Hsiu-Chi;
Chen, Wei-Ying;
Tseng, Joseph T.;
Chang, Wei-Lun;
Sheu, Bor-Shyang

Publication type:

Article

Early intervention prevented intrauterine fetus death due to placental abruption in woman with JAK2V617F mutation-positive essential thrombocythemia.

Published in:

Ginekologia Polska, 2025, v. 96, n. 4, p. 324, doi. 10.5603/gpl.101184

By:

Handziuk, Artur;
Galli, Dominika;
Pralat, Aleksandra;
Kandula, Zuzanna;
Lewandowski, Krzysztof;
Markwitz, Wieslaw

Publication type:

Article

Natural Compounds in Cancer Therapy: Revealing the Role of Flavonoids in Renal Cell Carcinoma Treatment.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 620, doi. 10.3390/biom15050620

By:

Chen, Zixuan;
Liu, Min

Publication type:

Article

IL6/CCL2 from M2-polarized microglia promotes breast cancer brain metastasis and the reversal effect of β-elemene.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1547333

By:

Feng, Qian;
Li, Cai-Zhi;
Zou, Yi-Hua;
Wang, Xue-Yu;
Yang, Xia;
Zhang, Rong;
Liu, Zhong-Qiu;
Zhang, Rong-Rong

Publication type:

Article

Benefits of the Topical JAK Inhibitor Delgocitinib in a Patient With Pediatric Localized Scleroderma.

Published in:

Pediatric Dermatology, 2025, v. 42, n. 3, p. 666, doi. 10.1111/pde.15844

By:

Yamamoto, Mayuko;
Nakajima, Kimiko;
Matsuda, Mayuko;
Takahashi, Aya;
Nakai, Kozo

Publication type:

Article

Dynamics of vector competence for dengue virus type 2 in rural and urban populations of Aedes albopictus: implications for infectious disease control.

Published in:

Parasites & Vectors, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13071-025-06826-8

By:

Khan, Jehangir;
Adil, Muhammad;
Junyan, Zhang;
Zhang, Dongjing;
Deng, Yidong;
Lv, Zhiyue;
Chen, Tao

Publication type:

Article

JAK-STAT inhibitors in noninfectious uveitis – A review.

Published in:

Indian Journal of Ophthalmology, 2025, v. 73, n. 6, p. 807, doi. 10.4103/IJO.IJO_61_25

By:

Pyare, Richa;
Shaikh, Nawazish;
Sen, Ahana;
Kene, Rakshita;
Bagri, Narendra;
Janarthanan, Mahesh;
Chawla, Rohan;
Ramanan, Athimalaipet V;
Dutta Majumder, Parthopratim

Publication type:

Article

The mechanisms of Brucea javanica in the treatment of oral squamous cell carcinoma: a network pharmacology, molecular docking, and experimental study.

Published in:

European Journal of Medical Research, 2025, v. 30, n. 1, p. 1, doi. 10.1186/s40001-025-02686-1

By:

Li, MingKang;
Zhan, Juan;
Lai, YiHan;
Ma, YuJie;
Wei, HongCheng;
Jiang, Lin;
Zha, JuanJuan;
Shao, YiSen;
Wang, Wei

Publication type:

Article

Regulation of programmed death ligand 1 expression by interferon‐γ and tumour necrosis factor‐α in canine tumour cell lines.

Published in:

Veterinary & Comparative Oncology, 2023, v. 21, n. 2, p. 279, doi. 10.1111/vco.12886

By:

Owaki, Ryo;
Deguchi, Tatsuya;
Konnai, Satoru;
Maekawa, Naoya;
Okagawa, Tomohiro;
Hosoya, Kenji;
Kim, Sangho;
Sunaga, Takafumi;
Okumura, Masahiro

Publication type:

Article

SIRT1 and ZNF350 as novel biomarkers for osteoporosis: a bioinformatics analysis and experimental validation.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09406-8

By:

Zhu, Naiqiang;
Hou, Jingyi;
Si, Jingyuan;
Yang, Ning;
Chen, Bin;
Wei, Xu;
Zhu, Liguo

Publication type:

Article

Egr-1 functions as a master switch regulator of remote ischemic preconditioning-induced cardioprotection.

Published in:

Basic Research in Cardiology, 2020, v. 115, n. 1, p. 1, doi. 10.1007/s00395-019-0763-9

By:

Billah, M.;
Ridiandries, A.;
Rayner, B. S.;
Allahwala, U. K.;
Dona, A.;
Khachigian, L. M.;
Bhindi, R.

Publication type:

Article

Cardioprotective effect of ghrelin against myocardial infarction-induced left ventricular injury via inhibition of SOCS3 and activation of JAK2/STAT3 signaling.

Published in:

Basic Research in Cardiology, 2018, v. 113, n. 2, p. 0, doi. 10.1007/s00395-018-0671-4

By:

Eid, Refaat A.;
Alkhateeb, Mahmoud A.;
Eleawa, Samy;
Al-Hashem, Fahaid H.;
Al-Shraim, Mubarak;
El-kott, Attalla Farag;
Zaki, Mohamed Samir Ahmed;
Dallak, Mohammad A.;
Aldera, Hussain

Publication type:

Article

The Great Atopic Dermatitis Treatment Debate: Biologics vs JAK Inhibitors.

Published in:

Patient Care (Online), 2025, p. 2

By:

Halsey, Grace

Publication type:

Article

The PRL2 phosphatase up-regulates miR-21 through activation of the JAK2/STAT3 pathway to down-regulate the PTEN tumor suppressor.

Published in:

Biochemical Journal, 2025, v. 482, n. 7, p. 341, doi. 10.1042/BCJ20240626

By:

Qinglin Li;
Yunpeng Bai;
Cavender, Sarah M.;
Yiming Miao;
Meke, Frederick Nguele;
Lasse-Opsahl, Emily L.;
Peipei Zhu;
Doody, Gina M.;
Tao, W. Andy;
Zhong-Yin Zhang

Publication type:

Article

Understanding interleukin 11 as a disease gene and therapeutic target.

Published in:

Biochemical Journal, 2023, v. 480, n. 23, p. 1987, doi. 10.1042/BCJ20220160

By:

Cook, Stuart A.

Publication type:

Article

MaBoSS 2.0: an environment for stochastic Boolean modeling.

Published in:

Bioinformatics, 2017, v. 33, n. 14, p. 2226, doi. 10.1093/bioinformatics/btx123

By:

Stoll, Gautier;
Caron, Barthélémy;
Viara, Eric;
Dugourd, Aurélien;
Zinovyev, Andrei;
Naldi, Aurélien;
Kroemer, Guido;
Barillot, Emmanuel;
Calzone, Laurence

Publication type:

Article

Detection of Inflammatory Signaling in Individuals with Bardet-Biedl Syndrome Presenting Symptoms of Polycystic Kidney Disease.

Published in:

Jentashapir Journal of Cellular & Molecular Biology, 2024, v. 15, n. 2, p. 1, doi. 10.5812/jcp-140747

By:

Khouzani, Mohammad Shiravi;
Kandasamy, Krishnaveni

Publication type:

Article

ACSM3 Suppresses Ovarian Cancer Progression by Inactivating the IFN‐γ/JAK/STAT3 Signaling Pathway.

Published in:

Advanced Biology, 2025, v. 9, n. 3, p. 1, doi. 10.1002/adbi.202400093

By:

Wang, Juan;
Sun, Yanqiu;
Wu, Ruixue

Publication type:

Article

Hydrazinocurcumin Induced Autophagy and Affected Cell Proliferation by Downregulating the JAK/STAT3 Signaling Pathway in Skin Squamous Cell Carcinoma.

Published in:

Advanced Biology, 2023, v. 7, n. 10, p. 1, doi. 10.1002/adbi.202300009

By:

Mao, Qifen;
Xia, Xufen;
Luo, Hongbin;
Jin, Li;
Li, Ying;
Zhu, Jinjun;
Wang, Yuan;
Shangguan, Zuifei;
Xu, Jiangyan

Publication type:

Article

Viral IL-10 can promote the proliferation, migration and invasion of nasopharyngeal carcinoma cells and inhibit their apoptosis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-01937-1

By:

Qiu, Qin;
Yang, Xingyu;
Li, Xiaojiang;
Ren, Yanxin;
Huang, Ning

Publication type:

Article

Modulation of esophageal squamous cell carcinoma progression: the impact of CCR7 on JAK2/STAT3 signaling pathway.

Published in:

Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-024-01289-2

By:

Zhang, Xuewen;
An, Yuji;
Mai, Dongmei;
Huang, Wan;
Zeng, Weian

Publication type:

Article

Modulation of esophageal squamous cell carcinoma progression: the impact of CCR7 on JAK2/STAT3 signaling pathway.

Published in:

Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-024-01289-2

By:

Zhang, Xuewen;
An, Yuji;
Mai, Dongmei;
Huang, Wan;
Zeng, Weian

Publication type:

Article

Repurposing FDA-approved compounds to target JAK2 for colon cancer treatment.

Published in:

Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-024-01050-9

By:

Chandrasekhar, Bavya;
Gor, Ravi;
Ramalingam, Satish;
Thiagarajan, Anuradha;
Sohn, Honglae;
Madhavan, Thirumurthy

Publication type:

Article

The Role of CXCL13 in GC‐1 Cell Cycle Arrest Induced by Titanium Dioxide Nanoparticles Through JAK2/STAT3 Signaling Pathway.

Published in:

Journal of Applied Toxicology, 2025, v. 45, n. 5, p. 830, doi. 10.1002/jat.4747

By:

Lei, Yuzhu;
Dong, Ruoyun;
Sun, Chenhao;
Hu, Yunhua;
Yan, Yizhong;
Song, Guanling;
Wang, Yan

Publication type:

Article

Synergistic inhibition of gastric cancer cell proliferation by concanavalin A and silibinin via attenuation of the JAK/STAT3 signaling pathway and molecular docking analysis.

Published in:

Hereditas, 2025, v. 162, n. 1, p. 1, doi. 10.1186/s41065-025-00438-z

By:

Hua, Gaoyan;
Zhao, Lisha;
Zeng, Xianjing;
Luo, Liang

Publication type:

Article

Exploration of the molecular mechanism of modified Danggui Liuhuang Decoction in treating central precocious puberty and its effects on hypothalamic-pituitary-gonadal axis hormones.

Published in:

Hereditas, 2025, v. 162, n. 1, p. 1, doi. 10.1186/s41065-025-00420-9

By:

Liu, Xiaqing;
Li, Pinggan;
Yang, Xiangna;
Xie, Ting;
Xu, Hua

Publication type:

Article

Tropisetron balances immune responses via TLR2, TLR4 and JAK2/STAT3 signalling pathway in LPS‐stimulated PBMCs.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2021, v. 128, n. 5, p. 669, doi. 10.1111/bcpt.13565

By:

Karimollah, Alireza;
Hemmatpur, Anahid;
Hosseini, Nafise;
Manshadi, Mahdi Dehghan

Publication type:

Article

Revealing Molecular Mechanisms of the Bioactive Saponins from Edible Root of Platycodon grandiflorum in Combating Obesity.

Published in:

Plants (2223-7747), 2024, v. 13, n. 8, p. 1123, doi. 10.3390/plants13081123

By:

Han, Bincheng;
Luo, Jinhai;
Xu, Baojun

Publication type:

Article

瘦素对牦牛乳腺上皮细胞中SOCS3和STAT3蛋白表达的影响及催乳素的作用.

Published in:

Journal of Nanjing Agricultural University / Nanjuing Nongye Daxue Xuebao, 2023, v. 46, n. 2, p. 360, doi. 10.7685/jnau.202110033

By:

董宝霞;
杨玉莹;
张勤文;
魏青;
荆海霞

Publication type:

Article

Primary immunodeficiency‐related genes in neonatal intensive care unit patients with various genetic immune abnormalities: a multicentre study in China.

Published in:

Clinical & Translational Immunology, 2021, v. 10, n. 3, p. 1, doi. 10.1002/cti2.1266

By:

Zhu, Tianwen;
Gong, Xiaohui;
Bei, Fei;
Ma, Li;
Sun, Jingjing;
Wang, Jian;
Qiu, Gang;
Sun, Jianhua;
Sun, Yu;
Zhang, Yongjun

Publication type:

Article

Porphyromonas gingivalis and Lactobacillus rhamnosus GG regulate the Th17/Treg balance in colitis via TLR4 and TLR2.

Published in:

Clinical & Translational Immunology, 2020, v. 9, n. 11, p. 1, doi. 10.1002/cti2.1213

By:

Jia, Lu;
Wu, Ruiqing;
Han, Nannan;
Fu, Jingfei;
Luo, Zhenhua;
Guo, Lijia;
Su, Yingying;
Du, Juan;
Liu, Yi

Publication type:

Article

Dual role of miR-155 and exosomal miR-155 in tumor angiogenesis: implications for cancer progression and therapy.

Published in:

European Journal of Medical Research, 2025, v. 30, n. 1, p. 1, doi. 10.1186/s40001-025-02618-z

By:

Hussain, Qusay Mohammed;
Al-Hussainy, Ali Fawzi;
Sanghvi, Gaurav;
Roopashree, R.;
Kashyap, Aditya;
Anand, D. Alex;
Panigrahi, Rajashree;
Shavazi, Nargiz;
Taher, Sada Ghalib;
Alwan, Mariem;
Jawad, Mahmood;
Mushtaq, Hiba

Publication type:

Article

HPV11E6/E7 induces nasal epithelial hyperplasia through JAK2/STAT3 signaling pathway.

Published in:

European Journal of Medical Research, 2025, v. 30, n. 1, p. 1, doi. 10.1186/s40001-025-02496-5

By:

Zhang, Yi;
Tian, Kaisai;
Zheng, Liying;
Zhu, Gaohan;
Zhao, Runyu;
Zhou, Enhui;
Xue, Xiaocheng;
Huang, Shuixian;
Chen, Xiaoping;
Hu, Baoji;
Yao, Wenhao

Publication type:

Article

Uncover the Underlying Mechanism of Drug-Induced Myopathy by Using Systems Biology Approaches.

Published in:

International Journal of Genomics, 2017, p. 1, doi. 10.1155/2017/9264034

By:

Li, Dong;
Li, Aixin;
Zhou, Hairui;
Wang, Xi;
Li, Peng;
Bi, Sheng;
Teng, Yang

Publication type:

Article

A novel immune‑related lncRNA as a prognostic biomarker in HER2<sup>+</sup> breast cancer.

Published in:

Oncology Letters, 2024, v. 27, n. 6, p. N.PAG, doi. 10.3892/ol.2024.14402

By:

Li, Xinwei;
Meng, Yue;
Gu, Bing

Publication type:

Article

miR-451a suppression of IL-6R can inhibit proliferation and increase apoptosis through the JAK2/STAT3 pathway in multiple myeloma.

Published in:

Oncology Letters, 2020, v. 20, n. 6, p. N.PAG, doi. 10.3892/ol.2020.12202

By:

Zhong, Ling;
Xu, Zhuyu;
Jin, Xin;
He, Yuan;
Zhang, Jianbo;
Jiang, Tao;
Chen, Jiao

Publication type:

Article

SUMO4 small interfering RNA attenuates invasion and migration via the JAK2/STAT3 pathway in non-small cell lung cancer cells.

Published in:

Oncology Letters, 2020, v. 20, n. 5, p. 1, doi. 10.3892/ol.2020.12088

By:

JIN-XIAO LIANG;
WEI GAO;
XIAO-WEI ZENG;
GUO-PING CHENG;
LEI CAI;
KAI-YI TAO;
XUN YANG

Publication type:

Article

Downregulation of miR-19a inhibits the proliferation and promotes the apoptosis of osteosarcoma cells by regulating the JAK2/STAT3 pathway.

Published in:

Oncology Letters, 2020, v. 20, n. 5, p. 1, doi. 10.3892/ol.2020.12033

By:

JIANGQIANG CHEN;
ZUHUI CHEN

Publication type:

Article

Mechanisms of JAK-STAT signaling pathway mediated by CXCL8 gene silencing on epithelial-mesenchymal transition of human cutaneous melanoma cells.

Published in:

Oncology Letters, 2020, v. 20, n. 2, p. 1973, doi. 10.3892/ol.2020.11706

By:

Hu, Xiaorui;
Yuan, Lili;
Ma, Teng

Publication type:

Article

Identification of glioblastoma-specific prognostic biomarkers via an integrative analysis of DNA methylation and gene expression.

Published in:

Oncology Letters, 2020, v. 20, n. 2, p. 1619, doi. 10.3892/ol.2020.11729

By:

Mao, Yu Kun;
Liu, Zhi Bo;
Cai, Lin

Publication type:

Article

Prognostic value of key genes of the JAK-STAT signaling pathway in patients with cutaneous melanoma.

Published in:

Oncology Letters, 2020, v. 19, n. 3, p. 1928, doi. 10.3892/ol.2020.11287

By:

Pan, Fuqiang;
Wang, Qiaoqi;
Li, Sizhu;
Huang, Rui;
Wang, Xiangkun;
Liao, Xiwen;
Mo, Haiyan;
Zhang, Liming;
Zhou, Xiang

Publication type:

Article

Time-series clustering of cytokine expression after transarterial chemoembolization in patients with hepatocellular carcinoma.

Published in:

Oncology Letters, 2020, v. 19, n. 2, p. 1175, doi. 10.3892/ol.2019.11209

By:

Qi, Feng;
Wang, Lingxiao;
Huang, Peixin;
Zhao, Zhiying;
Yang, Biwei;
Xia, Jinglin

Publication type:

Article

Decreased expression of TXNIP predicts poor prognosis in patients with clear cell renal cell carcinoma.

Published in:

Oncology Letters, 2020, v. 19, n. 1, p. 763, doi. 10.3892/ol.2019.11165

By:

Gao, Yuan;
Qi, Jin-Chun;
Li, Xiaoyu;
Sun, Jian-Ping;
Ji, Hong;
Li, Qing-Huai

Publication type:

Article