Works matching DE "ZYMOGENS"

Results: 198

Upregulation of an Artificial Zymogen by Proteolysis.

Published in:

Angewandte Chemie, 2016, v. 128, n. 38, p. 11759, doi. 10.1002/ange.201605010

By:

Liu, Zhe;
Lebrun, Vincent;
Kitanosono, Taku;
Mallin, Hendrik;
Köhler, Valentin;
Häussinger, Daniel;
Hilvert, Donald;
Kobayashi, Shu;
Ward, Thomas R.

Publication type:

Article

Molecular insights into the inhibitory mechanism of bi-functional bis-tryptoline triazole against β-secretase (BACE1) enzyme.

Published in:

Amino Acids, 2019, v. 51, n. 10-12, p. 1593, doi. 10.1007/s00726-019-02797-0

By:

Narang, Simranjeet Singh;
Goyal, Deepti;
Goyal, Bhupesh

Publication type:

Article

Insights into the regulation of the matriptaseprostasin proteolytic system.

Published in:

Biochemical Journal, 2020, v. 477, n. 22, p. 4349, doi. 10.1042/BCJ20200630

By:

Holt-Danborg, Lasse;
Skovbjerg, Signe;
Goderum, Kristian W.;
Nonboe, Annika W.;
Stankevic, Evelina;
Frost, Ásdis K.;
Vitved, Lars;
Jensen, Jan K.;
Vogel, Lotte K.

Publication type:

Article

Inhibition of an active zymogen protease: the zymogen form of matriptase is regulated by HAI-1 and HAI-2.

Published in:

Biochemical Journal, 2020, v. 477, n. 9, p. 1779, doi. 10.1042/BCJ20200182

By:

Skovbjerg, Signe;
Holt-Danborg, Lasse;
Nonboe, Annika W.;
Zebin Hong;
Frost, Ásdís K.;
Schar, Christine R.;
Thomas, Cecilia C.;
Vitved, Lars;
Jensen, Jan K.;
Vogel, Lotte K.

Publication type:

Article

Transcriptomic response study of brittle star Ophiothrix exigua to sediment burial.

Published in:

Hydrobiologia, 2023, v. 850, n. 16, p. 3645, doi. 10.1007/s10750-023-05271-x

By:

Wang, Xiaogu;
Li, Yujie;
Meng, Fanxu

Publication type:

Article

Discovery of Benzyl Tetraphosphonate Derivative as Inhibitor of Human Factor Xia.

Published in:

ChemistryOpen, 2020, v. 9, n. 11, p. 1161, doi. 10.1002/open.202000277

By:

Kar, Srabani;
Mottamal, Madhusoodanan;
Al‐Horani, Rami A.

Publication type:

Article

Personality, immune response and reproductive success: an appraisal of the pace-of-life syndrome hypothesis.

Published in:

Journal of Animal Ecology, 2017, v. 86, n. 4, p. 932, doi. 10.1111/1365-2656.12684

By:

Monceau, Karine;
Dechaume‐Moncharmont, François‐Xavier;
Moreau, Jérôme;
Lucas, Camille;
Capoduro, Rémi;
Motreuil, Sébastien;
Moret, Yannick;
Ardia, Daniel

Publication type:

Article

Activity and post-prandial regulation of digestive enzyme activity along the Pacific hagfish (Eptatretus stoutii) alimentary canal.

Published in:

PLoS ONE, 2019, v. 14, n. 4, p. 1, doi. 10.1371/journal.pone.0215027

By:

Weinrauch, Alyssa M.;
Schaefer, Christina M.;
Goss, Greg G.

Publication type:

Article

Crystal structures of human procathepsin H.

Published in:

PLoS ONE, 2018, v. 13, n. 7, p. 1, doi. 10.1371/journal.pone.0200374

By:

Hao, Yue;
Purtha, Whitney;
Cortesio, Christa;
Rui, Huan;
Gu, Yan;
Chen, Hao;
Sickmier, E. Allen;
Manzanillo, Paolo;
Huang, Xin

Publication type:

Article

Cigarette toxin 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces experimental pancreatitis through α7 nicotinic acetylcholine receptors (nAChRs) in mice.

Published in:

PLoS ONE, 2018, v. 13, n. 6, p. 1, doi. 10.1371/journal.pone.0197362

By:

Alahmari, A. A.;
Sreekumar, B.;
Patel, V.;
Ashat, M.;
Alexandre, M.;
Uduman, A. K.;
Akinbiyi, E. O.;
Ceplenski, A.;
Shugrue, C. A.;
Kolodecik, T. R.;
Tashkandi, N.;
Messenger, S. W.;
Groblewski, G. E.;
Gorelick, F. S.;
Thrower, E. C.

Publication type:

Article

Simultaneous demonstration of gelatinolytic activity, morphology, and immunohistochemical reaction using zymography film.

Published in:

Medical Molecular Morphology, 2013, v. 46, n. 4, p. 193, doi. 10.1007/s00795-013-0021-4

By:

Kanomata, Naoki;
Hasebe, Takahiro;
Moriya, Takuya;
Ochiai, Atsushi

Publication type:

Article

Segment-Specific Expression of MMP/TIMP in the Oviduct of Llama (Lama glama) and Gelatinolytic Activity in the Oviductal Fluid.

Published in:

International Journal of Morphology, 2017, v. 35, n. 2, p. 615, doi. 10.4067/S0717-95022017000200038

By:

Zampini, Renato;
Apichela, Silvana;
Sari, Luciana;
Angiono, Georgina;
Lombardo, Daniel;
Miceli, Dora;
Argañaraz, Martin

Publication type:

Article

Prognostic and predictive value of cathepsin X in serum from colorectal cancer patients.

Published in:

BMC Cancer, 2014, v. 14, p. 1, doi. 10.1186/1471-2407-14-259

By:

Vižin, Tjaša;
Christensen, Ib Jarle;
Wilhelmsen, Michael;
Nielsen, Hans Jørgen;
Kos, Janko

Publication type:

Article

Prognostic and predictive value of cathepsin X in serum from colorectal cancer patients.

Published in:

BMC Cancer, 2014, v. 14, n. 1, p. 1, doi. 10.1186/1471-2407-14-259

By:

Vižin, Tjaša;
Christensen, Ib Jarle;
Wilhelmsen, Michael;
Nielsen, Hans Jørgen;
Kos, Janko

Publication type:

Article

Prophenoloxidase Activation Is Required for Survival to Microbial Infections in Drosophila.

Published in:

PLoS Pathogens, 2014, v. 10, n. 5, p. 1, doi. 10.1371/journal.ppat.1004067

By:

Binggeli, Olivier;
Neyen, Claudine;
Poidevin, Mickael;
Lemaitre, Bruno

Publication type:

Article

Curcumin inhibits BACE1 expression through the interaction between ERβ and NFκB signaling pathway in SH-SY5Y cells.

Published in:

Molecular & Cellular Biochemistry, 2020, v. 463, n. 1/2, p. 161, doi. 10.1007/s11010-019-03638-0

By:

Huang, Pan;
Zheng, Nan;
Zhou, Hai-bing;
Huang, Jian

Publication type:

Article

Sodium retention in the nephrotic syndrome and the non-enzymatic function of prostasin.

Published in:

2022

By:

Svenningsen, Per

Publication type:

Editorial

Enhancement of Streptomyces transglutaminase activity and pro-peptide cleavage efficiency by introducing linker peptide in the C-terminus of the pro-peptide.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2013, v. 40, n. 3/4, p. 317, doi. 10.1007/s10295-012-1221-y

By:

Chen, Kangkang;
Liu, Song;
Wang, Guangsheng;
Zhang, Dongxu;
Du, Guocheng;
Chen, Jian;
Shi, Zhongping

Publication type:

Article

Evaluation of Cell Death Potential of Lepidium sativum Seed Extracts in MCF-7 Cells and Molecular Docking-based Correlation of Identified Bioactive Components with Human Caspase-6 Protein.

Published in:

Indian Journal of Pharmaceutical Education & Research, 2022, v. 56, n. 1, p. 166, doi. 10.5530/ijper.56.1.19

By:

R., Rajasekaran;
P. K., Suresh

Publication type:

Article

Bioinformatics analysis of structures and ligand-bindings of predicted zymogen granule protein observed on Bali cattle (Bos javanicus) saliva.

Published in:

Journal of Advanced Veterinary & Animal Research, 2021, v. 8, n. 2, p. 224, doi. 10.5455/javar.2021.h506

By:

Kisworo, Djoko;
Depamede, Sulaiman Ngongu

Publication type:

Article

Structural insights into the role of the prosegment binding loop in a papain‐superfamily cysteine protease from Treponema denticola.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2025, v. 81, n. 2, p. 53, doi. 10.1107/S2053230X25000378

By:

Clark, N. D.;
Li, C.;
Malkowski, M. G.

Publication type:

Article

Protective effects of activated protein C (APC) on free groin flaps after secondary venous stasis in the rat model.

Published in:

Clinical Hemorheology & Microcirculation, 2015, v. 59, n. 4, p. 335, doi. 10.3233/CH-131803

By:

Wallmichrath, J.;
Knab, R.;
Baumeister, R. G. H.;
Holzbach, T.;
Giunta, R. E.;
Frick, A.

Publication type:

Article

Characterization and molecular docking study of cathepsin L inhibitory peptides (SnuCalCpIs) from Calotropis procera R. Br.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-09854-x

By:

Kwon, Chang Woo;
Yeo, Subin;
Chang, Pahn-Shick

Publication type:

Article

The Role of Cutinsomes in Plant Cuticle Formation.

Published in:

Cells (2073-4409), 2020, v. 9, n. 8, p. 1778, doi. 10.3390/cells9081778

By:

Stępiński, Dariusz;
Kwiatkowska, Maria;
Wojtczak, Agnieszka;
Polit, Justyna Teresa;
Domínguez, Eva;
Heredia, Antonio;
Popłońska, Katarzyna

Publication type:

Article

PDGFR and IGF-1R Inhibitors Induce a G2/M Arrest and Subsequent Cell Death in Human Glioblastoma Cell Lines.

Published in:

Cells (2073-4409), 2018, v. 7, n. 9, p. 131, doi. 10.3390/cells7090131

By:

Carrasco-Garcia, Estefania;
Martinez-Lacaci, Isabel;
Mayor-López, Leticia;
Tristante, Elena;
Carballo-Santana, Mar;
García-Morales, Pilar;
Ventero Martin, Maria Paz;
Fuentes-Baile, Maria;
Rodriguez-Lescure, Álvaro;
Saceda, Miguel

Publication type:

Article

Cysteine Proteases: Modes of Activation and Future Prospects as Pharmacological Targets.

Published in:

Frontiers in Pharmacology, 2016, p. 1, doi. 10.3389/fphar.2016.00107

By:

Verma, Sonia;
Dixit, Rajnikant;
Pandey, Kailash C.

Publication type:

Article

Loss of tolerance to glycoprotein 2 isoforms 1 and 4 is associated with Crohn's disease of the pouch.

Published in:

Alimentary Pharmacology & Therapeutics, 2018, v. 48, n. 11/12, p. 1251, doi. 10.1111/apt.15034

By:

Cummings, Donelle;
Cruise, Michael;
Lopez, Rocio;
Roggenbuck, Dirk;
Jairath, Vipul;
Wang, Yinghong;
Shen, Bo;
Rieder, Florian

Publication type:

Article

Chemical zymogens for the protein cysteinome.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32609-1

By:

Montasell, Mireia Casanovas;
Monge, Pere;
Carmali, Sheiliza;
Dias Loiola, Livia Mesquita;
Andersen, Dante Guldbrandsen;
Løvschall, Kaja Borup;
Søgaard, Ane Bretschneider;
Kristensen, Maria Merrild;
Pütz, Jean Maurice;
Zelikin, Alexander N.

Publication type:

Article

Molecular and in vivo studies of a glutamate-class prolyl-endopeptidase for coeliac disease therapy.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32215-1

By:

del Amo-Maestro, Laura;
Mendes, Soraia R.;
Rodríguez-Banqueri, Arturo;
Garzon-Flores, Laura;
Girbal, Marina;
Rodríguez-Lagunas, María José;
Guevara, Tibisay;
Franch, Àngels;
Pérez-Cano, Francisco J.;
Eckhard, Ulrich;
Gomis-Rüth, F. Xavier

Publication type:

Article

Tiny but Mighty: Vipera ammodytes meridionalis (Eastern Long-Nosed Viper) Ontogenetic Venom Variations in Procoagulant Potency and the Impact on Antivenom Efficacies.

Published in:

Toxins, 2024, v. 16, n. 9, p. 396, doi. 10.3390/toxins16090396

By:

Qiao, Zichen;
Jones, Lee;
Bourke, Lachlan A.;
Seneci, Lorenzo;
Chowdhury, Abhinandan;
Violette, Aude;
Fourmy, Rudy;
Soria, Raul;
Aldridge, Matt;
Fry, Bryan G.

Publication type:

Article

Blood Lines: Intraspecific and Interspecific Variations in Anticoagulant Actions of Agkistrodon Viperid Venoms.

Published in:

Toxins, 2024, v. 16, n. 7, p. 291, doi. 10.3390/toxins16070291

By:

Coimbra, Francisco C. P.;
Sanchez, Elda E.;
Lomonte, Bruno;
Gutiérrez, José María;
Calvete, Juan J.;
Fry, Bryan G.

Publication type:

Article

The Clot Thickens: Differential Coagulotoxic and Cardiotoxic Activities of Anguimorpha Lizard Venoms.

Published in:

Toxins, 2024, v. 16, n. 6, p. 283, doi. 10.3390/toxins16060283

By:

Dobson, James;
Chowdhury, Abhinandan;
Tai-A-Pin, Jeremie;
van der Ploeg, Harold;
Gillett, Amber;
Fry, Bryan G.

Publication type:

Article

Zymophagy: Selective Autophagy of Secretory Granules.

Published in:

International Journal of Cell Biology, 2012, p. 1, doi. 10.1155/2012/396705

By:

Vaccaro, Maria I.

Publication type:

Article

Conserved Prosegment Residues Stabilize a Late-Stage Folding Transition State of Pepsin Independently of Ground States.

Published in:

PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0101339

By:

Dee, Derek R.;
Horimoto, Yasumi;
Yada, Rickey Y.

Publication type:

Article

Examination of the Ligand-Binding and Enzymatic Properties of a Bilin-Binding Protein from the Poisonous Caterpillar Lonomia obliqua.

Published in:

PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0095424

By:

Veiga, Ana B. G.;
Ribeiro, José M. C.;
Francischetti, Ivo M. B.;
Xu, Xueqing;
Guimarães, Jorge A.;
Andersen, John F.

Publication type:

Article

Human Cancer Cells Retain Modest Levels of Enzymatically Active Matriptase Only in Extracellular Milieu following Induction of Zymogen Activation.

Published in:

PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0092244

By:

Chu, Li-Ling;
Xu, Yuan;
Yang, Jie-Ru;
Hu, Yi-An;
Chang, Hsiang-Hua;
Lai, Hong-Yu;
Tseng, Chun-Che;
Wang, Hue-Yu;
Johnson, Michael D.;
Wang, Jehng-Kang;
Lin, Chen-Yong

Publication type:

Article

Detection of Active Matriptase Using a Biotinylated Chloromethyl Ketone Peptide.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077146

By:

Godiksen, Sine;
Soendergaard, Christoffer;
Friis, Stine;
Jensen, Jan K.;
Bornholdt, Jette;
Sales, Katiuchia Uzzun;
Huang, Mingdong;
Bugge, Thomas H.;
Vogel, Lotte K.

Publication type:

Article

The Proline-Rich Motif of the proDer p 3 Allergen Propeptide Is Crucial for Protease-Protease Interaction.

Published in:

PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0068014

By:

Dumez, Marie-Eve;
Herman, Julie;
Campisi, Vincenzo;
Bouaziz, Ahlem;
Rosu, Frédéric;
Luxen, André;
Vandenberghe, Isabel;
de Pauw, Edwin;
Frère, Jean-Marie;
Matagne, André;
Chevigné, Andy;
Galleni, Moreno

Publication type:

Article

Cold Adaptation, Ca2+ Dependency and Autolytic Stability Are Related Features in a Highly Active Cold-Adapted Trypsin Resistant to Autoproteolysis Engineered for Biotechnological Applications.

Published in:

PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0072355

By:

Olivera-Nappa, Alvaro;
Reyes, Fernando;
Andrews, Barbara A.;
Asenjo, Juan A.

Publication type:

Article

Effect of Nutrient Restriction and Re-Feeding on Calpain Family Genes in Skeletal Muscle of Channel Catfish (Ictalurus punctatus).

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0059404

By:

Preziosa, Elena;
Liu, Shikai;
Terova, Genciana;
Gao, Xiaoyu;
Liu, Hong;
Kucuktas, Huseyin;
Terhune, Jeffery;
Liu, Zhanjiang

Publication type:

Article

Validation of Expression Patterns for Nine miRNAs in 204 Lymph-Node Negative Breast Cancers.

Published in:

PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0048692

By:

Jonsdottir, Kristin;
Janssen, Susanne R.;
Da Rosa, Fabiana C.;
Gudlaugsson, Einar;
Skaland, Ivar;
Baak, Jan P. A.;
Janssen, Emiel A. M.

Publication type:

Article

Activation of Soluble Adenylyl Cyclase Protects against Secretagogue Stimulated Zymogen Activation in Rat Pancreaic Acinar Cells.

Published in:

PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0041320

By:

Kolodecik, Thomas R.;
Shugrue, Christine A.;
Thrower, Edwin C.;
Levin, Lonny R.;
Buck, Jochen;
Gorelick, Fred S.

Publication type:

Article

A Novel Function of Noc2 in Agonist-Induced Intracellular Ca2+ Increase during Zymogen-Granule Exocytosis in Pancreatic Acinar Cells.

Published in:

PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0037048

By:

Ogata, Sho;
Miki, Takashi;
Seino, Susumu;
Tamai, Seiichi;
Kasai, Haruo;
Nemoto, Tomomi

Publication type:

Article

Molecular characterization of EcCLP1, a new putative cathepsin L protease from Echinococcus canadensis.

Published in:

Parasite (1252607X), 2024, v. 31, p. 1, doi. 10.1051/parasite/2024036

By:

Naidich, Ariel;
Gutierrez, Ariana M.;
Camicia, Federico

Publication type:

Article

Angiogenesis and remodelling in human thoracic aortic aneurysms.

Published in:

Cardiovascular Research, 2014, v. 104, n. 1, p. 147, doi. 10.1093/cvr/cvu196

By:

Kessler, Ketty;
Borges, Luciano F.;
Ho-Tin-Noé, Benoît;
Jondeau, Guillaume;
Michel, Jean-Baptiste;
Vranckx, Roger

Publication type:

Article

Caspase‐3: A primary target for natural and synthetic compounds for cancer therapy.

Published in:

Chemical Biology & Drug Design, 2021, v. 98, n. 1, p. 144, doi. 10.1111/cbdd.13860

By:

Yadav, Poonam;
Yadav, Ramakant;
Jain, Shweta;
Vaidya, Ankur

Publication type:

Article

Caspase-14 suppresses GCM1 acetylation and inhibits placental cell differentiation.

Published in:

FASEB Journal, 2013, v. 27, n. 7, p. 2818, doi. 10.1096/fj.12-224279

By:

Yi-Hung Wu;
Hsiao-Fan Lo;
Sih-Han Chen;
Hungwen Chen

Publication type:

Article

Boosting toxic protein biosynthesis: transient in vivo inactivation of engineered bacterial alkaline phosphatase.

Published in:

Microbial Cell Factories, 2020, v. 19, n. 1, p. N.PAG, doi. 10.1186/s12934-020-01424-y

By:

Krawczun, Natalia;
Bielawa, Marta;
Szemiako, Kasjan;
Łubkowska, Beata;
Sobolewski, Ireneusz;
Zylicz-Stachula, Agnieszka;
Skowron, Piotr M.

Publication type:

Article

Foliar application of sodium selenate induces regulation in yield formation, grain quality characters and 2-acetyl-1-pyrroline biosynthesis in fragrant rice.

Published in:

BMC Plant Biology, 2019, v. 19, n. 1, p. 1, doi. 10.1186/s12870-019-2104-4

By:

Luo, Haowen;
Du, Bin;
He, Longxin;
Zheng, Axiang;
Pan, Shenggang;
Tang, Xiangru

Publication type:

Article

Fractional killing arises from cell-to-cell variability in overcoming a caspase activity threshold.

Published in:

Molecular Systems Biology, 2015, v. 11, n. 5, p. n/a, doi. 10.15252/msb.20145584

By:

Roux, Jérémie;
Hafner, Marc;
Bandara, Samuel;
Sims, Joshua J;
Hudson, Hannah;
Chai, Diana;
Sorger, Peter K

Publication type:

Article