Title: Hydroxychloroquine and Risk of Diabetes in Patients With Rheumatoid Arthritis.
Authors: Wasko, Mary Chester M.; Hubert, Helen B.; Lingala, Vijaya Bharathi; Elliott, Jennifer R.; Luggen, Michael E.; Fries, James F.; Ward, Michael M.
Abstract: This article offers a study to determine if the use of hydroxychloroquine in patients with rheumatoid arthritis can lessen the incidence of diabetes among this population. Antimalarials such as this drug have a long-standing safe and inexpensive history for treatment of autoimmune diseases and may improve glucose tolerance and prevent diabetes. The results of the study showed that among patients with rheumatoid arthritis, the use of hydroxychloroquine is associated with a reduced risk of diabetes. The study will follow up on the patients for 20 years.
Subjects: DIABETES prevention; ANTIMALARIALS; RHEUMATOID arthritis; AUTOIMMUNE diseases; BLOOD sugar; CLINICAL trial registries; HEALTH outcome assessment; PATIENTS
Publication: JAMA: Journal of the American Medical Association, 2007, Vol 298, Issue 2, p187
ISSN: 0098-7484
Publication type: Academic Journal
DOI: 10.1001/jama.298.2.187

Hydroxychloroquine and Risk of Diabetes in Patients With Rheumatoid Arthritis.

Wasko, Mary Chester M.; Hubert, Helen B.; Lingala, Vijaya Bharathi; Elliott, Jennifer R.; Luggen, Michael E.; Fries, James F.; Ward, Michael M.