Results
Title

Brain Stimulation With Cognitive Remediation Might Slow Cognitive Decline in Depression.

Authors

Anderer, Samantha

Abstract

A recent study published in JAMA Psychiatry suggests that a combination of cognitive remediation and noninvasive brain stimulation using low-level electrical currents may help slow cognitive decline in older adults with major depression, a risk factor for dementia. The study involved 375 older adults with remitted major depressive disorder or mild cognitive impairment who received active cognitive remediation exercises and direct current stimulation targeting the prefrontal cortex. Results showed that those who received the combined treatment experienced a slower cognitive decline compared to those in the sham intervention group, with positive effects lasting up to 6 years, particularly on executive function and verbal memory.

Subjects

COGNITIVE remediation; MILD cognitive impairment; BRAIN stimulation; MENTAL depression; COGNITION disorders

Publication

JAMA: Journal of the American Medical Association, 2025, Vol 333, Issue 1, p12

ISSN

0098-7484

Publication type

Academic Journal

DOI

10.1001/jama.2024.24259