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A host receptor enables type 1 pilus-mediated pathogenesis of Escherichia coli pyelonephritis.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009314
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Gnotobiotic rainbow trout (Oncorhynchus mykiss) model reveals endogenous bacteria that protect against Flavobacterium columnare infection.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009302
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Baseline T cell immune phenotypes predict virologic and disease control upon SARS-CoV infection in Collaborative Cross mice.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009287
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The NF-κB regulator Bcl-3 restricts terminal differentiation and promotes memory cell formation of CD8<sup>+</sup> T cells during viral infection.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009249
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Human FcRn expression and Type I Interferon signaling control Echovirus 11 pathogenesis in mice.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009252
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Temporally integrated single cell RNA sequencing analysis of PBMC from experimental and natural primary human DENV-1 infections.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009240
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Infection of porcine small intestinal enteroids with human and pig rotavirus A strains reveals contrasting roles for histo-blood group antigens and terminal sialic acids.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009237
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Ebola virus triggers receptor tyrosine kinase-dependent signaling to promote the delivery of viral particles to entry-conducive intracellular compartments.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009275
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Functional analyses of epidemic Clostridioides difficile toxin B variants reveal their divergence in utilizing receptors and inducing pathology.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009197
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Hematopoietic cell-mediated dissemination of murine cytomegalovirus is regulated by NK cells and immune evasion.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009255
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Strain-specific genome evolution in Trypanosoma cruzi, the agent of Chagas disease.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009254
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Single cell resolution of SARS-CoV-2 tropism, antiviral responses, and susceptibility to therapies in primary human airway epithelium.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009292
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Kaposi's sarcoma-associated herpesvirus processivity factor (PF-8) recruits cellular E3 ubiquitin ligase CHFR to promote PARP1 degradation and lytic replication.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009261
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Bartonella type IV secretion effector BepC induces stress fiber formation through activation of GEF-H1.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009065
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Bartonella effector protein C mediates actin stress fiber formation via recruitment of GEF-H1 to the plasma membrane.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1008548
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Lentiviral transduction facilitates RNA interference in the nematode parasite Nippostrongylus brasiliensis.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009286
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Nucleosome landscape reflects phenotypic differences in Trypanosoma cruzi life forms.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009272
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High genetic variability of Schmallenberg virus M-segment leads to efficient immune escape from neutralizing antibodies.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009247
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A multi-omics approach to Epstein-Barr virus immortalization of B-cells reveals EBNA1 chromatin pioneering activities targeting nucleotide metabolism.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009208
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Rapid adaptation to human protein kinase R by a unique genomic rearrangement in rhesus cytomegalovirus.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009088
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Reliable, scalable functional genetics in bloodstream-form Trypanosoma congolense in vitro and in vivo.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009224
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G protein-coupled receptors: The choreographers of innate immunity in Caenorhabditis elegans.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009151
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Multiple roles of PP2A binding motif in hepatitis B virus core linker and PP2A in regulating core phosphorylation state and viral replication.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009230
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SARS-CoV-2 variants with mutations at the S1/S2 cleavage site are generated in vitro during propagation in TMPRSS2-deficient cells.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009233
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Outer membrane permeabilization by the membrane attack complex sensitizes Gram-negative bacteria to antimicrobial proteins in serum and phagocytes.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009227
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Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009246
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An Alba-domain protein required for proteome remodelling during trypanosome differentiation and host transition.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009239
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A host cell long noncoding RNA NR_033736 regulates type I interferon-mediated gene transcription and modulates intestinal epithelial anti-Cryptosporidium defense.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009241
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Interferon regulatory factor 1 (IRF1) and anti-pathogen innate immune responses.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009220
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Inositol phosphates promote HIV-1 assembly and maturation to facilitate viral spread in human CD4<sup>+</sup> T cells.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009190
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Bacterial nucleomodulins: A coevolutionary adaptation to the eukaryotic command center.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009184
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MEK/ERK signaling is a critical regulator of high-risk human papillomavirus oncogene expression revealing therapeutic targets for HPV-induced tumors.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009216
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Phase separation and DAXX redistribution contribute to LANA nuclear body and KSHV genome dynamics during latency and reactivation.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009231
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Activation of EphA2-EGFR signaling in oral epithelial cells by Candida albicans virulence factors.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009221
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In vivo antagonistic role of the Human T-Cell Leukemia Virus Type 1 regulatory proteins Tax and HBZ.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009219
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Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen dysregulates expression of MCL-1 by targeting FBW7.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009179
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The coronavirus proofreading exoribonuclease mediates extensive viral recombination.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009226
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Naturally occurring substitution in one amino acid in VHSV phosphoprotein enhances viral virulence in flounder.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009213
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In vivo nanoscale analysis of the dynamic synergistic interaction of Bacillus thuringiensis Cry11Aa and Cyt1Aa toxins in Aedes aegypti.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009199
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A novel sialic acid-binding adhesin present in multiple species contributes to the pathogenesis of Infective endocarditis.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009222
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Hydroxychloroquine-mediated inhibition of SARS-CoV-2 entry is attenuated by TMPRSS2.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009212
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Enhanced biofilm and extracellular matrix production by chronic carriage versus acute isolates of Salmonella Typhi.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009209
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Relationship between CD4 T cell turnover, cellular differentiation and HIV persistence during ART.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009214
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Dissecting genetic and sex-specific sources of host heterogeneity in pathogen shedding and spread.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009196
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K18-hACE2 mice develop respiratory disease resembling severe COVID-19.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009195
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Immunological design of commensal communities to treat intestinal infection and inflammation.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009191
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Intra-host changes in Kaposi sarcoma-associated herpesvirus genomes in Ugandan adults with Kaposi sarcoma.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1008594
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Extensive proteomic and transcriptomic changes quench the TCR/CD3 activation signal of latently HIV-1 infected T cells.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1008748
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T-bet-dependent ILC1- and NK cell-derived IFN-γ mediates cDC1-dependent host resistance against Toxoplasma gondii.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1008299
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A novel mode of control of nickel uptake by a multifunctional metallochaperone.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009193
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