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Mechanism of YJKL Decoction in Treating of PCOS Infertility by Integrative Approach of Network Pharmacology and Experimental Verification.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3853, doi. 10.2147/DDDT.S456656
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- Article
Sinomenine Alleviates Rheumatoid Arthritis by Suppressing the PI3K-Akt Signaling Pathway, as Demonstrated Through Network Pharmacology, Molecular Docking, and Experimental Validation.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3523, doi. 10.2147/DDDT.S475959
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- Article
Treatment of Melasma with Tranexamic Acid Essence Combined with Iontophoresis: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3659, doi. 10.2147/DDDT.S472922
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- Article
The Role of Plasma Trough Concentration of Voriconazole and Voriconazole N-Oxide in Its Hepatotoxicity in Adult Patients.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3617, doi. 10.2147/DDDT.S475706
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- Article
The Impact of Fentanyl on the Effective Dose of Remimazolam-Induced Sedation in Elderly Female Patients: An Up-and-Down Sequential Allocation Trial.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3729, doi. 10.2147/DDDT.S473662
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- Article
The Effect of Low-Dose Dexmedetomidine on Perioperative Neurocognitive Dysfunction in Elderly Patients Undergoing Endoscopic Retrograde Cholangiopancreatography (ERCP): A Randomized, Controlled, Double-Blind Trial.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3715, doi. 10.2147/DDDT.S470514
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- Article
The Effect of Lidocaine-Prilocaine Cream Combined with or Without Remimazolam on VAS and APAIS Anxiety Score in Patient Undergoing Spinal Anesthesia.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3429, doi. 10.2147/DDDT.S468486
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- Article
Transforming Healthcare with Nanomedicine: A SWOT Analysis of Drug Delivery Innovation.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3499, doi. 10.2147/DDDT.S470210
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- Article
Subanesthetic Dose of Esketamine Improves the Sedative and Analgesic Effects of Dexmedetomidine and Remifentanil in Liposuction Anesthesia: A Prospective, Double-Blinded, Randomized Controlled Trial.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3645, doi. 10.2147/DDDT.S470891
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- Article
Saikosaponins Targeting Programmed Cell Death as Anticancer Agents: Mechanisms and Future Perspectives.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3697, doi. 10.2147/DDDT.S470455
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- Article
Protective Effects of Chlorogenic Acid on Cerebral Ischemia/Reperfusion Injury Rats by Regulating Oxidative Stress-Related Nrf2 Pathway [Retraction].
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3547, doi. 10.2147/DDDT.S490477
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- Article
Cyanidin-3-O-Glucoside Improves Colonic Motility During Severe Acute Pancreatitis by Inhibiting the H<sub>2</sub>S-Regulated AMPK/mTOR Pathway [Retraction].
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3739, doi. 10.2147/DDDT.S492610
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- Article
Remimazolam in General Anesthesia: A Comprehensive Review of Its Applications and Clinical Efficacy.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3487, doi. 10.2147/DDDT.S474854
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- Article
Polydopamine-Based Biomaterials in Orthopedic Therapeutics: Properties, Applications, and Future Perspectives.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3765, doi. 10.2147/DDDT.S473007
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- Article
The Anti-Diabetic Effects of Medicinal Plants Belonging to the Liliaceae Family: Potential Alpha Glucosidase Inhibitors.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3595, doi. 10.2147/DDDT.S464100
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- Article
Therapeutic Potential of Natural Resources Against Endometriosis: Current Advances and Future Perspectives.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3667, doi. 10.2147/DDDT.S464910
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- Article
Metformin's Enigma: Bridging Gaps in Research on Potential Benefits & Associated Risks - A Critical Plea for Comprehensive Investigation [Letter].
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3643, doi. 10.2147/DDDT.S487044
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- Article
Flavopereirine Suppresses the Progression of Human Oral Cancer by Inhibiting the JAK-STAT Signaling Pathway via Targeting LASP1 [Letter].
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3923, doi. 10.2147/DDDT.S491658
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- Article
Comparison Between Esketamine and Alfentanil for Hysteroscopy: A Prospective, Double-Blind, Randomized Controlled Trial [Letter].
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3727, doi. 10.2147/DDDT.S491659
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- Article
Isolation and Quantification of Palmatine from Fibraurea tinctoria Lour: In Vitro Antioxidant Activity and In Silico Antidiabetic Activity Evaluation.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3443, doi. 10.2147/DDDT.S454091
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- Article
Erythrina subumbrans (Hassk) Merr. (Fabaceae) Inhibits Insulin Resistance in the Adipose Tissue of High Fructose-Induced Wistar Rats.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3825, doi. 10.2147/DDDT.S472660
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- Article
Enhance the Antimycobacterial Activity of Streptomycin with Ebselen as an Antibiotic Adjuvant Through Disrupting Redox Homeostasis.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3811, doi. 10.2147/DDDT.S475535
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- Article
Effects of Propofol, Low and High Doses of Remimazolam on Hemodynamic and Inflammatory Response in Laparoscopic Surgery [Letter].
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3921, doi. 10.2147/DDDT.S489524
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- Article
Effect of Alleviating Preoperative Anxiety on Gastrointestinal Function Recovery After Laparoscopic High Ligation of the Hernia Sac in Children with Indirect Inguinal Hernia.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3477, doi. 10.2147/DDDT.S461097
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- Article
ED-71 Ameliorates Bone Loss in Type 2 Diabetes Mellitus by Enhancing Osteogenesis Through Upregulation of the Circadian Rhythm Coregulator BMAL1.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3903, doi. 10.2147/DDDT.S470684
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- Article
Comparison Between Esketamine and Alfentanil for Hysteroscopy: A Prospective, Double-Blind, Randomized Controlled Trial.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3629, doi. 10.2147/DDDT.S472651
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- Publication type:
- Article
Combining Network Pharmacology and Transcriptomics to Investigate the Mechanisms of Yujiang Paidu Decoction in the Treatment of Chronic Rhinosinusitis with Nasal Polyps.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3791, doi. 10.2147/DDDT.S461769
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- Article
Combinational Antitumor Strategies Based on the Active Ingredients of Toad Skin and Toad Venom.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3549, doi. 10.2147/DDDT.S469832
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- Article
Chemistry, Pharmacology and Therapeutic Potential of Decursin: A Promising Natural Lead for New Drug Discovery and Development.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3741, doi. 10.2147/DDDT.S476279
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- Article
CaMK II in Cardiovascular Diseases, Especially CaMK II-δ: Friends or Enemies.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3461, doi. 10.2147/DDDT.S473251
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- Article
Based on UPLC-Q-TOF/MS and Network Pharmacology to Explore the Mechanism of Qingre Lishi Decoction in the Treatment of Psoriasis.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3871, doi. 10.2147/DDDT.S467066
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- Article
Apigenin Attenuates Transverse Aortic Constriction-Induced Myocardial Hypertrophy: The Key Role of miR-185-5p/SREBP2-Mediated Autophagy.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3841, doi. 10.2147/DDDT.S464004
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- Article
A Randomized, Double-Blind, Parallel-Group Phase I Study Comparing the Pharmacokinetics, Safety, and Immunogenicity of CMAB015, a Candidate Secukinumab Biosimilar, with Its Reference Product Cosentyx<sup>®</sup> in Healthy Chinese Male Subjects.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3891, doi. 10.2147/DDDT.S470619
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- Article
Therapeutic Potential of Solanum Alkaloids with Special Emphasis on Cancer: A Comprehensive Review.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3063, doi. 10.2147/DDDT.S470925
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- Article
Impact of Lipids on Insulin Resistance: Insights from Human and Animal Studies.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3337, doi. 10.2147/DDDT.S468147
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- Article
Inflammation Can Be a High-Risk Factor for Mucosal Nonunion of MRONJ by Regulating SIRT1 Signaling When Treated with an Oncologic Dose of Zoledronate.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 2793, doi. 10.2147/DDDT.S456811
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- Article
Evaluating the Therapeutic Potential of Ublituximab in the Treatment of MS: Design, Development and Place in Therapy.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3025, doi. 10.2147/DDDT.S388410
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- Article
The Discovery of GIT1/β-Pix Inhibitors: Virtual Screening and Biological Evaluation of New Small-molecule Compounds with Anti-invasion Effect in Gastrointestinal Neoplasms.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3075, doi. 10.2147/DDDT.S461609
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- Article
Tangzhiping Decoction Improves Glucose and Lipid Metabolism and Exerts Protective Effects Against White Adipose Tissue Dysfunction in Prediabetic Mice.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 2951, doi. 10.2147/DDDT.S462603
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- Article
Study on the Underlying Mechanism of Yinhua Gout Granules in the Treatment of Gouty Arthritis by Integrating Transcriptomics and Network Pharmacology.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3089, doi. 10.2147/DDDT.S475442
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- Article
Therapeutic Effects of Qingchang Tongluo Decoction on Intestinal Fibrosis in Crohn's Disease: Network Pharmacology, Molecular Docking and Experiment Validation.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3269, doi. 10.2147/DDDT.S458811
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- Article
Schisandra chinensis Bee Pollen Extract Inhibits Proliferation and Migration of Hepatocellular Carcinoma HepG2 Cells via Ferroptosis-, Wnt-, and Focal Adhesion–Signaling Pathways.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 2745, doi. 10.2147/DDDT.S461581
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- Article
Antitumor Effects of Hydromorphone on Human Gastric Cancer Cells in vitro [Retraction].
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3267, doi. 10.2147/DDDT.S488449
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- Article
4-Amino-2-Trifluoromethyl-Phenyl Retinate Inhibits Proliferation, Invasion, and Migration of Breast Cancer Cells by Independently Regulating CRABP2 and FABP5 [Retraction].
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- Drug Design, Development & Therapy, 2024, v. 18, p. 2713, doi. 10.2147/DDDT.S484570
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- Article
Research Progress of Triptolide Against Fibrosis.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3255, doi. 10.2147/DDDT.S467929
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- Article
Chuanxiong Renshen Decoction Inhibits Alzheimer's Disease Neuroinflammation by Regulating PPARγ/NF-κB Pathway.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3209, doi. 10.2147/DDDT.S462266
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- Article
The Application Potential of the Regulation of Tregs Function by Irisin in the Prevention and Treatment of Immune-Related Diseases.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 3005, doi. 10.2147/DDDT.S465713
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- Article
Clinical Study of Flumazenil Antagonizing Remimazolam on Nausea and Vomiting After Gynecologic Day Surgery [Letter].
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- Drug Design, Development & Therapy, 2024, v. 18, p. 2919, doi. 10.2147/DDDT.S483180
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- Article
The Influence of Piriform Recess Instillation with Lidocaine Before Bronchoscopy on Post-General Anesthesia Cough: A Randomized Controlled Trial.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 2883, doi. 10.2147/DDDT.S458058
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- Article
Pharmacokinetics and Safety of Estradiol Valerate Tablet and Its Generic: A Phase 1 Bioequivalence Study in Healthy Chinese Postmenopausal Female Subjects.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 2891, doi. 10.2147/DDDT.S460681
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- Article