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Val109Asp Polymorphism of the Omentin-1 Gene and Incidence of Knee Osteoarthritis in a Chinese Han Population: A Correlation Analysis.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 5075, doi. 10.2147/DDDT.S340410
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- Article
Comparative Pharmacokinetics/Pharmacodynamics of Fixed-Dose Combination of Esomeprazole and Calcium Carbonate (AD-206) to the Conventional Esomeprazole.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 5099, doi. 10.2147/DDDT.S341271
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- Article
Pro-Angiogenic Effects of Essential Oil from Perilla frutescens and Its Main Component (Perillaldehyde) on Zebrafish Embryos and Human Umbilical Vein Endothelial Cells.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4985, doi. 10.2147/DDDT.S336826
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- Article
Cell-Penetrating Peptide-Modified Graphene Oxide Nanoparticles Loaded with Rictor siRNA for the Treatment of Triple-Negative Breast Cancer.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4961, doi. 10.2147/DDDT.S330059
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- Article
Simultaneous Determination of Loratadine and Its Metabolite Desloratadine in Beagle Plasma by LC-MS/MS and Application for Pharmacokinetics Study of Loratadine Tablets and Omeprazole‑Induced Drug–Drug Interaction.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 5109, doi. 10.2147/DDDT.S328106
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- Article
Progestin-Primed Ovarian Stimulation with Clomiphene Citrate Supplementation May Be More Feasible for Young Women with Diminished Ovarian Reserve Compared with Standard Progestin-Primed Ovarian Stimulation: A Retrospective Study.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 5087, doi. 10.2147/DDDT.S338748
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- Article
Protective Effects of Mogroside V on Oxidative Stress Induced by H<sub>2</sub>O<sub>2</sub> in Skin Fibroblasts.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4901, doi. 10.2147/DDDT.S337524
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- Article
Network Pharmacology and Experimental Validation to Reveal the Pharmacological Mechanisms of Liuwei Dihuang Decoction Against Intervertebral Disc Degeneration.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4911, doi. 10.2147/DDDT.S338439
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- Article
In vitro Preparation and Evaluation of Sustained-Release Microcapsules of Salvianolic Acid [Retraction].
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- Drug Design, Development & Therapy, 2021, v. 15, p. 5133, doi. 10.2147/DDDT.S354555
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- Article
Lactobacillus fermentum CQPC08 Attenuates Exercise-Induced Fatigue in Mice Through Its Antioxidant Effects and Effective Intervention of Galactooligosaccharide.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 5151, doi. 10.2147/DDDT.S317456
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- Article
Knockdown of TRIM8 Protects HK-2 Cells Against Hypoxia/Reoxygenation-Induced Injury by Inhibiting Oxidative Stress-Mediated Apoptosis and Pyroptosis via PI3K/Akt Signal Pathway.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4973, doi. 10.2147/DDDT.S333372
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- Article
Identification of Active Ingredients of Huangqi Guizhi Wuwu Decoction for Promoting Nerve Function Recovery After Ischemic Stroke Using HT22 Live-Cell-Based Affinity Chromatography Combined with HPLC-MS/MS.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 5165, doi. 10.2147/DDDT.S333418
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- Article
Drug Repurposing: Deferasirox Inhibits the Anti-Apoptotic Activity of Mcl-1.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 5035, doi. 10.2147/DDDT.S323077
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- Article
Establishment of Sunitinib-Resistant Xenograft Model of Renal Cell Carcinoma and the Identification of Drug-Resistant Hub Genes and Pathways.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 5061, doi. 10.2147/DDDT.S343718
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- Article
Dynamics of Endocytosis and Degradation of Antibody-Drug Conjugate T-DM1 in HER2 Positive Cancer Cells.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 5135, doi. 10.2147/DDDT.S344052
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- Article
Effects of Dezocine and Sufentanil on Th1/Th2 Balance in Breast Cancer Patients Undergoing Surgery.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4925, doi. 10.2147/DDDT.S326891
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- Article
Ventilagolin Suppresses Migration, Invasion and Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma Cells by Downregulating Pim-1.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4885, doi. 10.2147/DDDT.S327270
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- Article
Downregulation of IRF2 Alleviates Sepsis-Related Acute Kidney Injury in vitro and in vivo.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 5123, doi. 10.2147/DDDT.S334518
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- Article
Effect of Different Concentrations of Esmolol on Perioperative Hemodynamics and Analgesia in Patients Undergoing Colectomy: A Prospective, Randomized Controlled Study.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 5025, doi. 10.2147/DDDT.S337201
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- Article
New Progress in Improving the Delivery Methods of Bisphosphonates in the Treatment of Bone Tumors.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4939, doi. 10.2147/DDDT.S337925
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- Article
Bio-Guided Isolation of Two New Hypoglycemic Triterpenoid Saponins from Polygonum capitatum.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 5001, doi. 10.2147/DDDT.S341354
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- Article
Artemisinin Improves Acetylcholine-Induced Vasodilatation in Rats with Primary Hypertension.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4489, doi. 10.2147/dddt.s330721
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- Article
(Rose Bengal)/(Eosin Yellow)-Gold-Polypyrrole Hybrids: A Design for Dual Photo-Active Nano-System with Ultra-High Loading Capacity.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 5011, doi. 10.2147/DDDT.S338922
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- Article
Therapeutic Effects and Safe Uses of Plant-Derived Polyphenolic Compounds in Cardiovascular Diseases: A Review.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4713, doi. 10.2147/DDDT.S327238
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- Article
Transdermal Delivery of Telmisartan: Formulation, in vitro, ex vivo, Iontophoretic Permeation Enhancement and Comparative Pharmacokinetic Study in Rats.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4603, doi. 10.2147/DDDT.S327860
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- Article
Toxicological Evaluation of a Probiotic-Based Delivery System for P8 Protein as an Anti-Colorectal Cancer Drug.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4761, doi. 10.2147/DDDT.S319930
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- Article
A Validated HPLC-MS/MS Method for Quantification of Methotrexate and Application for Therapeutic Drug Monitoring in Children and Adults with Non-Hodgkin Lymphoma.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4575, doi. 10.2147/DDDT.S335122
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- Article
Exploring the Underlying Mechanism of Shenyankangfu Tablet in the Treatment of Glomerulonephritis Through Network Pharmacology, Machine Learning, Molecular Docking, and Experimental Validation.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4585, doi. 10.2147/DDDT.S333209
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- Article
Efficacy of Pre-Treatment with Remimazolam on Prevention of Propofol-Induced Injection Pain in Patients Undergoing Abortion or Curettage: A Prospective, Double-Blinded, Randomized and Placebo-Controlled Clinical Trial.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4551, doi. 10.2147/DDDT.S334100
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- Article
Chemistry, Biosynthesis, Physicochemical and Biological Properties of Rubiadin: A Promising Natural Anthraquinone for New Drug Discovery and Development.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4527, doi. 10.2147/DDDT.S338548
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- Article
Prunella vulgaris L. Attenuates Experimental Autoimmune Thyroiditis by Inhibiting HMGB1/TLR9 Signaling.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4559, doi. 10.2147/DDDT.S325814
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- Article
The Efficacy and Safety of Remimazolam Tosilate versus Etomidate-Propofol in Elderly Outpatients Undergoing Colonoscopy: A Prospective, Randomized, Single-Blind, Non-Inferiority Trial.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4675, doi. 10.2147/DDDT.S339535
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- Article
Inhibition of Lipopolysaccharide-Induced Inflammatory Bone Loss by Saikosaponin D is Associated with Regulation of the RANKL/RANK Pathway.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4741, doi. 10.2147/DDDT.S334421
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- Article
Ruxolitinib for Treatment of Steroid-Refractory Graft-versus-Host Disease: Real-World Data from Chinese Patients.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4875, doi. 10.2147/DDDT.S338752
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- Article
Oroxin B Attenuates Ovariectomy-Induced Bone Loss by Suppressing Osteoclast Formation and Activity.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4811, doi. 10.2147/DDDT.S328238
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- Article
Methylcobalamin Protects Melanocytes from H<sub>2</sub>O<sub>2</sub>-Induced Oxidative Stress by Activating the Nrf2/HO-1 Pathway.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4837, doi. 10.2147/DDDT.S336066
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- Article
Activation of GPR18 by Resolvin D2 Relieves Pain and Improves Bladder Function in Cyclophosphamide-Induced Cystitis Through Inhibiting TRPV1.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4687, doi. 10.2147/DDDT.S329507
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- Article
The Pharmacokinetic Effect of Itraconazole and Voriconazole on Ripretinib in Beagle Dogs by UPLC-MS/MS Technique.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4865, doi. 10.2147/DDDT.S337864
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- Article
Anti-Inflammatory Effects of Curcumin in the Inflammatory Diseases: Status, Limitations and Countermeasures.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4503, doi. 10.2147/DDDT.S327378
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- Article
Berberine Influences the Survival of Fat Grafting by Inhibiting Autophagy and Apoptosis of Human Adipose Derived Mesenchymal Stem Cells.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4795, doi. 10.2147/DDDT.S337215
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- Article
Hearing Protection Outcomes of Analog Electrode Arrays Coated with Different Drug-Eluting Polymer Films Implanted into Guinea Pig Cochleae [Corrigendum].
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4759, doi. 10.2147/DDDT.S349645
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- Article
A New Strategy for the Rapid Identification and Validation of the Direct Targets of Aconitine-Induced Cardiotoxicity.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4649, doi. 10.2147/DDDT.S335461
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- Article
A Retrospective Cohort Study Evaluates Clinical Value of Anlotinib in Persistent, Metastatic, or Recurrent Cervical Cancer After Failure of First-Line Therapy.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4665, doi. 10.2147/DDDT.S335870
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- Article
Clinical Effect of Doxycycline Combined with Compound Sulfamethoxazole and Rifampicin in the Treatment of Brucellosis Spondylitis.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4733, doi. 10.2147/DDDT.S341242
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- Article
UPLC–MS/MS and Network Pharmacology-Based Analysis of Bioactive Anti-Depression Compounds in Betel Nut.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4827, doi. 10.2147/DDDT.S335312
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- Article
The Effect of Metformin on the Proliferation, Apoptosis and CD133 mRNA Expression of Colon Cancer Stem Cells by Upregulation of miR 342-3p.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4633, doi. 10.2147/DDDT.S336490
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- Article
New Insights of Anti-Hyperglycemic Agents and Traditional Chinese Medicine on Gut Microbiota in Type 2 Diabetes.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4849, doi. 10.2147/DDDT.S334325
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- Article
Unravelling the Protective Effects of Emodin Against Cyclophosphamide Induced Gonadotoxicity in Male Wistar Rats.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4403, doi. 10.2147/DDDT.S333383
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- Article
A review on the molecular basis underlying the protective effects of Andrographis paniculata and andrographolide against myocardial injury.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4615, doi. 10.2147/DDDT.S331027
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- Article
Mechanism of Yinqin Oral Liquid in the Treatment of Chronic Pharyngitis Based on Network Pharmacology.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 4413, doi. 10.2147/DDDT.S324139
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- Article