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Synthesis, biochemical characterization and in silico investigation of 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid derivatives: dual action mode inhibitors of urease and virulent bacterial stains.
Published in:
Biochemical Journal, 2022, v. 479, n. 19, p. 2035, doi. 10.1042/BCJ20220395
By:
- Irshad, Sajid;
- Ahmad, Saeed;
- Khan, Shafi Ullah;
- Khan, Mohsin Abbas;
- Ejaz, Syeda Abida;
- Rao, Huma;
- Khurshid, Umair;
- Ahmed, Aftab;
- Shahzad, Nadeem;
- Al-kahtani, Hamad M.;
- Waheed, Affan;
- Wani, Tanveer A.;
- Aborode, Abdullahi Tunde
Publication type:
Article
Regulation of CHK1 inhibitor resistance by a c-Rel and USP1 dependent pathway.
Published in:
Biochemical Journal, 2022, v. 479, n. 19, p. 2063, doi. 10.1042/BCJ20220102
By:
- Hunter, Jill E.;
- Campbell, Amy E.;
- Hannaway, Nicola L.;
- Kerridge, Scott;
- Luli, Saimir;
- Butterworth, Jacqueline A.;
- Sellier, Helene;
- Mukherjee, Reshmi;
- Dhillon, Nikita;
- Sudhindar, Praveen D.;
- Shukla, Ruchi;
- Brownridge, Philip J.;
- Bell, Hayden L.;
- Coxhead, Jonathan;
- Taylor, Leigh;
- Leary, Peter;
- Hasoon, Megan S. R.;
- Collins, Ian;
- Garrett, Michelle D.;
- Eyers, Claire E.
Publication type:
Article
Up-regulation of the PI3K/AKT and RHO/RAC/PAK signalling pathways in CHK1 inhibitor resistant Eµ-Myc lymphoma cells.
Published in:
Biochemical Journal, 2022, v. 479, n. 19, p. 2131, doi. 10.1042/BCJ20220103
By:
- Hunter, Jill E.;
- Campbell, Amy E.;
- Kerridge, Scott;
- Fraser, Callum;
- Hannaway, Nicola L.;
- Luli, Saimir;
- Ivanova, Iglika;
- Brownridge, Philip J.;
- Coxhead, Jonathan;
- Taylor, Leigh;
- Leary, Peter;
- Hasoon, Megan S. R.;
- Eyers, Claire E.;
- Perkins, Neil D.
Publication type:
Article
Claspin haploinsufficiency leads to defects in fertility, hyperplasia and an increased oncogenic potential.
Published in:
Biochemical Journal, 2022, v. 479, n. 19, p. 2115, doi. 10.1042/BCJ20220101
By:
- Madgwick, Suzanne;
- Luli, Saimir;
- Sellier, Helene;
- Butterworth, Jacqueline A.;
- Leslie, Jack;
- Moore, Adam J.;
- Corbin, Emma K.;
- Yemm, Adrian I.;
- Chiremba, Robson T.;
- Tiniakos, Dina;
- Oakley, Fiona;
- Perkins, Neil D.;
- Hunter, Jill E.
Publication type:
Article
PON2 mediates mitochondrial dysfunction in tracheal epithelial cells in response to a quorum sensing molecule N-(-3-oxododecanoyl)-L-homoserine lactone.
Published in:
Biochemical Journal, 2022, v. 479, n. 19, p. 2013, doi. 10.1042/BCJ20220100
By:
- Whitt, Aaron G.;
- Shuhan Meng;
- Jiu-Zhen Jin;
- Conroy, Lindsey R.;
- McNally, Lindsey A.;
- Burlison, Joseph A.;
- Hill, Bradford G.;
- Clem, Brian F.;
- White, Carl;
- Chi Li
Publication type:
Article
Mutation of the RelA(p65) Thr505 phosphosite disrupts the DNA replication stress response leading to CHK1 inhibitor resistance.
Published in:
Biochemical Journal, 2022, v. 479, n. 19, p. 2087, doi. 10.1042/BCJ20220089
By:
- Hunter, Jill E.;
- Campbell, Amy E.;
- Butterworth, Jacqueline A.;
- Sellier, Helene;
- Hannaway, Nicola L.;
- Luli, Saimir;
- Floudas, Achilleas;
- Kenneth, Niall S.;
- Moore, Adam J.;
- Brownridge, Philip J.;
- Thomas, Huw D.;
- Coxhead, Jonathan;
- Taylor, Leigh;
- Leary, Peter;
- Hasoon, Megan S. R.;
- Knight, Andrew M.;
- Garrett, Michelle D.;
- Collins, Ian;
- Eyers, Claire E.;
- Perkins, Neil D.
Publication type:
Article
Mechanisms of TNF-independent RIPK3-mediated cell death.
Published in:
Biochemical Journal, 2022, v. 479, n. 19, p. 2040, doi. 10.1042/BCJ20210724
By:
- Tummers, Bart;
- Green, Douglas R.
Publication type:
Article

Found: 7

Synthesis, biochemical characterization and in silico investigation of 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid derivatives: dual action mode inhibitors of urease and virulent bacterial stains.

Regulation of CHK1 inhibitor resistance by a c-Rel and USP1 dependent pathway.

Up-regulation of the PI3K/AKT and RHO/RAC/PAK signalling pathways in CHK1 inhibitor resistant Eµ-Myc lymphoma cells.

Claspin haploinsufficiency leads to defects in fertility, hyperplasia and an increased oncogenic potential.

PON2 mediates mitochondrial dysfunction in tracheal epithelial cells in response to a quorum sensing molecule N-(-3-oxododecanoyl)-L-homoserine lactone.

Mutation of the RelA(p65) Thr505 phosphosite disrupts the DNA replication stress response leading to CHK1 inhibitor resistance.

Mechanisms of TNF-independent RIPK3-mediated cell death.